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Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer

original article

open access

published version

Piccinno, Gianmarco

;

Thompson, Kelsey N.

;

Manghi, Paolo

;

Ghazi, Andrew R.

;

Thomas, Andrew Maltez

;

Blanco-Miguez, Aitor

;

Asnicar, Francesco

;

Mladenovic, Katarina

;

Pinto, Federica

;

Armanini, Federica

;

Puncochar, Michal

;

Piperni, Elisa

;

Heidrich, Vitor

;

Fackelmann, Gloria

;

Ferrero, Giulio

;

Tarallo, Sonia

;

Nguyen, Long H.

;

Yan, Yan

;

Keles, Nazim A.

;

Tuna, Bilge G.

;

Vymetálková, Veronika

;

Trompetto, Mario

;

Liška, Václav

;

Hucl, Tomáš

;

Vodička, Pavel

;

Bencsikova, Beatrix

;

Carnogurska, Martina

;

Popovici, Vlad

;

Marmorino, Federica

;

Cremolini, Chiara

;

Pardini, Barbara

;

Cordero, Francesca

;

Song, Mingyang

;

Chan, Andrew T.

;

Derosa, Lisa

;

Zitvogel, Laurence

;

Huttenhower, Curtis

;

Naccarati, Alessio

;

Budinska, Eva

;

Segata, Nicola

2025

,

Nature Medicine

,

31

(7)

Associations between the gut microbiome and colorectal cancer (CRC) have been uncovered, but larger and more diverse studies are needed to assess their potential clinical use. We expanded upon 12 metagenomic datasets of ...

Nucleotide composition shapes gene expression in Wolbachia pipientis: a role for MidA methyltransferase?

original article

open access

published version

Papaleo, Stella

;

Panelli, Simona

;

Bitar, Ibrahim

;

Sterzi, Lodovico

;

Nodari, Riccardo

;

Comandatore, Francesco

2025

,

American Society for Microbiology

,

mSystems

,

10

(9)

Wolbachia pipientis is an obligate intracellular bacterium, associated with several arthropods and filarial nematodes. Wolbachia establishes a variety of symbiotic relationships with its hosts, with consequent genomic ...

Genomic analysis of extended-spectrum beta-lactamase-producing E. coli from Czech diary calves and their caretakers

original article

open access

accepted version

Masarikova, Martina

;

Papouskova, Aneta

;

Sukkar, Iva

;

Laušová, Jarmila

;

Cejkova, Darina

;

Cizek, Alois

2025

,

Frontiers in Veterinary Science

,

12

(March)

INTRODUCTION: The increasing prevalence of antimicrobial resistance in livestock, particularly the dissemination of extended-spectrum beta-lactamase-producing Escherichia coli, poses a significant zoonotic and public health ...

Visual presentation of age differences in relative survival of hematological neoplasms in Sweden and the neighboring countries

original article

open access

published version

Hemminki, Kari Jussi

;

Zitrický, František

2025

,

Annals of Hematology

,

104

(3)

For many hematological malignancies (HMs) survival among older patients is compromised. We want to test the most up-to-date age-group-specific survival differences in five hematological malignancies, Hodgkin lymphoma (HL), ...

Percutaneous transthoracic needle biopsy of lung lesions is a safe method associated with a very low risk of pleural recurrence

original article

open access

published version

Svatoň, Martin

;

Havel, David

;

Burešová, Marcela

;

Baxa, Jan

;

Hošek, Petr

2025

,

Biomedical Papers

,

169

(1)

AIM: Percutaneous transthoracic needle biopsy (PTNB), an alternative to bronchoscopic confirmation of lung lesions, is today being associated with a risk of pneumothorax and hemorrhage. Further, there are no data on the ...

Epigenetic Characterization of Squamous Cell Carcinoma and Mucoepidermoid Carcinoma Based on DNA Methylation Data: An In-Silico Study

abstract in journal

open access

published version

Othman, Bacem Abdullah Essam Othman Khalele

;

Skálová, Alena

2025

,

Oxford

,

Elsevier Ltd.

,

EJC Skin Cancer

,

3

(S1)

Background: A recent study demonstrated that parotid squamous cell carcinomas (SCCs) are most potentially metastatic cutaneous SCCs. To define whether epigenetic alterations may explain the different molecular events between ...

Native and decellularized porcine vena cava: Histological analysis and in vitro repopulation

original article

open access

published version

Massaro, Maria Stefania

;

Pálek, Richard

;

Malečková, Anna

;

Grajciarová, Martina

;

Červenková, Lenka

;

Polák, Robert

;

Šarčević, Sima

;

Ševčík, Jan

;

Bolek, Lukáš

;

Tonar, Zbyněk

;

Liška, Václav

;

Moulisová, Vladimíra

2025

,

Biomaterials Advances

,

177

(December)

Current standards in vascular reconstruction imply the use of autologous or synthetic material. Despite being standard, autologous grafts are limited by pathologies already affecting the patient and possible complications ...

Fosfomycin-resistant Escherichia coli: a FosA10 case in Italy

original article

open access

published version

Mattioni Marchetti, Vittoria

;

Petrizzi, Ilaria

;

Venturelli, Irene

;

Cassetti, Tiziana

;

Meschiari, Marianna

;

Migliavacca, Roberta

;

Bitar, Ibrahim

2025

,

JAC-Antimicrobial Resistance

,

7

(2)

BACKGROUND: FosA10-producing Enterobacterales have an extremely low incidence in Europe. PATIENTS AND METHODS: In March 2024, an 83-year-old woman, hospitalized in the Modena Province, developed an infection with ...

Prognostic Role of Prostate-specific Antigen Isoforms and Their Early Kinetics in Patients With Metastatic Castration-resistant Prostate Cancer Receiving New Generation Androgen Receptor Targeted Agents

original article

open access

published version

Fiala, Ondřej

;

Hošek, Petr

;

Korunková, Hana

;

Tkadlecová, Michaela

;

Hora, Milan

;

Šiková, Dominika

;

Stránský, Petr

;

Fínek, Jindřich

;

Kučera, Radek

;

Windrichová, Jindra

;

Topolčan, Ondřej

2025

,

Iōannīs G. Delīnasios

,

In Vivo

,

39

(2)

BACKGROUND/AIM: New generation androgen receptor-targeting agents (ARTA) have been in the spotlight for their efficacy in metastatic castration-resistant prostate cancer (mCRPC). Prostate-specific antigen (PSA) represents ...

Prioritization of predisposition genes for familial non-medullary thyroid cancer by whole-genome sequencing

original article

open access

published version

Srivastava, Aayushi

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Skopelitou, Diamanto

;

Miao, Beiping

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Giagiobbe, Sara

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Paramasivam, Nagarajan

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Kumar, Abhishek

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Diquigiovanni, Chiara

;

Bonora, Elena

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Bandapalli, Obul Reddy

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Försti, Asta

;

Hemminki, Kari Jussi

2025

,

BioScientifica

,

European Journal of Endocrinology

,

192

(4)

OBJECTIVE: Thyroid cancer (TC) is the most common endocrine malignancy, with 90%-95% of the cases representing non-medullary thyroid cancer (NMTC). Familial cases account only for a few of all cases and the underlying ...

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