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Mitochondrial Transfer Rescues Respiration to Support De Novo Pyrimidine Biosynthesis and Tumor Progression 

original article

open access

published version

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Dubišová, Mária

;

Boháčová, Klára

;

Nahácka, Zuzana

;

Kraus, Daniel

;

Novák, Jaromír

;

Dvořáková, Šárka

;

Brisudová, Petra

;

Danešová, Natálie

;

Selvi, Saba

;

Hrysiuk, Mariia

;

Endaya, Berwini Beduya

;

Botsios, Panagiotis

;

Le, Thi Dan Diem

;

Novotná, Monika

;

Vodenková, Soňa

;

Truksa, Jaroslav

;

Chalupský, Karel

;

Klíma, Kryštof

;

Procházka, Jan

;

Sedláček, Radislav

;

Mengarelli, Francesco

;

Orlando, Patrick

;

Tiano, Luca

;

Boukalová, Štěpána

;

Berridge, Michael V.

;

Zobalová, Renata

;

Neužil, Jiří

2026

,

American Association for Cancer Research

,

Cancer Research

,

86

(4)

Cancer cells with severe defects in mitochondrial DNA (mtDNA) can import mitochondria via horizontal mitochondrial transfer to restore respiration. Mitochondrial respiration is necessary for the activity of dihydroorotate ...

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Basal cell adenoma with S100 protein-positive "stroma": a distinct triphasic salivary gland neoplasm characterized by CTNNB1 mutation 

original article

open access

published version

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Skálová, Alena

;

Bradová, Martina

;

Laco, Jan

;

Vaněček, Tomáš

;

Hájková, Veronika

;

Martínek, Petr

;

Grendár, Marián

;

Querzoli, Giulia

;

Leivo, Ilmo

;

Michal, Michal

2026

,

Springer

,

Virchows Archiv

,

488

(2)

Basal cell adenoma (BCA) is a benign salivary neoplasm that exhibits a divergent spectrum of growth patterns, including cribriform, tubular, trabecular, membranous, and solid. A subset of BCAs is characterized by the ...

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SMARCA4-deficient carcinoma of the head and neck region: report of 8 new sinonasal and non-sinonasal cases and literature review 

original article

open access

published version

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Farkas, Mihaela

;

Agaimy, Abbas

;

Švajdler, Marián

;

Hauer, Lukáš

;

Martínek, Petr

;

Vaněček, Tomáš

;

Pivovarčíková, Kristýna

;

Prchlíková, Barbora

;

Simpson, Roderick H W

;

Gočárová, Klaudia

;

Vereš, Peter

;

Slavík, Petr

;

Behenská, Kristýna

;

Marjanovic, Ksenija

;

Michal, Michal

;

Skálová, Alena

;

Bradová, Martina

2026

,

Springer

,

Virchows Archiv

,

488

(5)

Neoplasms with inactivating mutations in SWI/SNF chromatin remodeling complex subunits gained attention in the head and neck (H&N) region due to their poor clinical outcomes. The sinonasal tract is a recognized "hot-spot" ...

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Hidden carriers: multidrug-resistant bacteria in hedgehogs from a wildlife rescue centre 

original article

open access

published version

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Masarikova, Martina

;

Papouskova, Aneta

;

Cejkova, Darina

;

Partovi Nasr, Minoo

;

Sukkar, Iva

;

Cizek, Alois

2026

,

Frontiers Media SA

,

Frontiers in Veterinary Science

,

13

(January)

Introduction Antimicrobial resistance (AMR) represents a growing One Health challenge at the human-animal-environment interface. Wildlife rescue centres may represent potential, underrecognized settings where resistant ...

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Familial Risks in 317 000 Patients With Prostate Cancer in Relation to Metastases and Survival-Guiding Diagnostics 

original article

open access

published version

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Hemminki, Kari Jussi

;

Zitrický, František

;

Sundquist, Kristina

;

Sundquist, Jan

;

Försti, Asta

;

Hemminki, Akseli

;

Hemminki, Otto

2026

,

Elsevier B.V.

,

European Urology Open Science

,

87

(May)

BackgroundSwedish nationwide family and cancer data offer the largest global resource for study of familial cancer. We focus here on familial risks in prostate cancer (PC) with questions on risk in individuals from families ...

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The Prognostic Role of Baseline and Early Dynamics of Peripheral Blood Cell Ratios in Metastatic Renal Cell Carcinoma Patients Treated With Nivolumab 

original article

open access

published version

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Creative Commons BY Icon

Creative Commons NC Icon

Creative Commons NC Icon

Fiala, Ondřej

;

Tkadlecová, Michaela

;

Kopecký, Jindřich

;

Hošek, Petr

;

Studentova, Hana

;

Vočka, Michal

;

Matějů, Martin

;

Lohynská, Radka

;

Šiková, Dominika

;

Stránský, Petr

;

Kučera, Radek

;

Zemankova, Anezka

;

Spisarova, Martina

;

Priester, Peter

;

Kouril, Jan

;

Büchler, Tomáš

;

Grmelova, Lucie

;

Melichar, Bohuslav

;

Poprach, Alexandr

2026

,

Iōannīs G. Delīnasios

,

In Vivo

,

40

(2)

BACKGROUND/AIM: Immune checkpoint inhibitors (ICI), including nivolumab, have become the cornerstone of systemic treatment in metastatic renal cell carcinoma (mRCC). Blood-derived biomarkers including neutrophil-to-lymphocyte ...

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Familial risks in prostate cancer between brothers and half-brothers as clues to germline genetic and environmental causes 

original article

open access

published version

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Hemminki, Kari Jussi

;

Zitrický, František

;

Sundquist, Kristina

;

Sundquist, Jan

;

Försti, Asta

;

Hemminki, Akseli

;

Hemminki, Oto

2026

,

Kluwer

,

Familial Cancer

,

25

(2)

Swedish family and cancer data constitute the largest source on familial cancer in the world. We analyze here familial risks in prostate cancer (PC) with focus on multiple affected brothers and comparation of full-brothers ...

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Integrated Genomic and Phenotypic Analyses Reveal Convergent Resistance Patterns in Clinical Candida tropicalis Isolates 

original article

open access

published version

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Chedraoui, Christy

;

Fattouh, Nour

;

El Hachem, Setrida

;

Sourenian, Tsolaire

;

El Bitar, Louna

;

El Moheb, Lama

;

Sleiman, Anna-Souraya

;

Bitar, Ibrahim

;

Husni, Rola

;

Khalaf, Roy A

2026

,

Blackwell

,

Mycoses

,

69

(5)

BACKGROUND: The incidence of Candida tropicalis isolation is increasing in hospital settings. High azole resistance and mortality rates make it a pathogen that requires further analysis. METHODS: Fourteen azole resistant ...

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O čem také přemýšlejí naši medici. Sborník studentských prací (2026) 

Thoughts of medical students. Collection of written projects (2026)

collection of papers

open access

published version

Gratis Apen Access Icon

Fiala, Luděk

;

Krejčová, Karolína

;

Krejčová, Kristýna

;

Batrakouli, Fani

;

Muliere, Pierluigi

;

Pulina, Francesca

;

Fraňková, Natálie

;

Pospíšil, Ondřej

;

Vavřina, Vojtěch

;

Jiráková, Natálie

;

Rybáková, Linda

;

Amin, Nisha Yara

;

Pfister, Nisha

;

Boudová, Nela

;

Fulnečková, Anna

;

Busse, Konrad

;

Čiháková, Tereza

;

Kulovaná, Tereza

;

Dagdeleni, Eirini

;

Kaza, Kristabel

;

Chan, Tiffany Chi Jing

;

Cordoba Rodriguez, Anna

;

Keřková, Sylvie

;

Parkánová, Michaela

;

Kešeláková, Markéta

;

Leupoldová, Miriam

;

Kocourková, Tereza

;

Neradová, Lucie

;

Spilková, Klára

;

Košek, Jindřich

;

Langová, Nela

;

Seichert, Metoděj

;

Krystlová, Yvona

;

Marková, Marie

;

Bryndačová, Leona

;

Kunftová, Karin

;

Štuksová, Carolina

;

Lust, Elina

;

Mecová, Martina

;

Němejcová, Viktorie

;

Morelli, Martina

;

Möbes, Lilli Sophie

;

Novák, Lukáš

;

Bláha, Jan

;

Novotná, Anna

;

Matějková, Anděla

;

Rezková, Vendula

;

Petrovičová, Andrea

;

Tausch, Jakub

;

Semiginovská, Klára Sofie

;

Pečenková, Michaela

;

Bauerová, Martina

;

Shafiei, Liyousa

;

Naderi Koupaei, Negin

;

Akhtari, Mohammadali

;

Nedela, Timo Joachim

;

Schneider, Simon

;

Školoudíková, Hana

;

Horský, Marek

;

Nekuda, Pavel

;

Plešmíd, Vojtěch

;

Šavlová, Eliška

;

Miller, Robert Joseph

;

Tenglerová, Nikola

;

Vobrubová, Julie

;

Vísnerová, Klára

;

Jankovcová, Klára-Marie

;

Broďániová, Barbora

;

Komínek, Adam

;

Hložková, Julie

;

Srkal, Jiří

;

Vršková, Lucie

;

Kaňková, Tereza

;

Miletín, Marek

;

Holub, Vojtěch

;

Šandová, Terezie

;

Šťavíčková, Nikola

;

Háčková, Anna

;

Hagenhoferová, Kateřina

;

Neuvirt, Maxim

;

Bubnenkov, Dmitrii

;

Drokin, Myron

;

Lee, Denis

2026

,

Plzeň

,

Psychiatrická klinika, Lékařská fakulta v Plzni Univerzity Karlovy

Výběr nejlepších esejí napsaných studenty Lékařské fakulty v Plzni Univerzity Karlovy pro předmět Lékařská psychologie a etika v akademickém roce 2025/2026.

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Comparative analysis of telomere length in peripheral blood of breast cancer BRCA1 mutation carriers and non-carriers 

original article

open access

published version

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Uttarilli, Anusha

;

Balounová, Kateřina

;

Tomášová, Kristýna

;

Hanak, Petr

;

Šašková, Kateřina

;

Vodička, Pavel

;

Vodičková, Ludmila

;

Hemminki, Kari Jussi

;

Lubinski, Jan

;

Kroupa, Michal

2026

,

Springer

,

Discover Oncology

,

17

(1)

INTRODUCTION: Breast cancer is the most prevalent malignancy among women worldwide. A significant portion of patients possess homologous recombination deficiency (HRD), often caused by BRCA1/2 mutations, which may sensitize ...

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Research Output Typejournal article (53)book (1)chapter (1)... View MoreDate Issued
2026 (55)
Faculty / University unitFaculty of Medicine in Pilsen (55)University Hospital in Pilsen (16)First Faculty of Medicine (10)Second Faculty of Medicine (8)University Hospital Hradec Králové (8)... View MoreDepartment / Institute / ClinicBiomedical Center (39)Department of Pathology (11)Department of Surgery (11)Department of Microbiology (10)Department of Oncology and Radiotherapy (5)... View More

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