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Emerging Role of Circulating Cell-Free RNA as a Non-Invasive Biomarker for Hepatocellular Carcinoma

original article

open access

published version

Shetti, Dattatrya

;

Mallela, Venkata Ramana

;

Ye, Wenjing

;

Sharif Bagheri, Mahyar

;

Ambrożkiewicz, Filip

;

Trailin, Andriy

;

Liška, Václav

;

Hemminki, Kari Jussi

2024

,

Critical Reviews in Oncology/Hematology

,

200

(August)

Hepatocellular carcinoma (HCC) is a severe neoplastic disease associated with high morbidity and mortality rates. HCC is often detected at advanced stages leading to ineffective curative treatments. Recently, liquid biopsy ...

Concomitant antihypertensive medication and outcome of patients with metastatic castration-resistant prostate cancer receiving enzalutamide or abiraterone acetate

original article

open access

published version

Fiala, Ondřej

;

Hošek, Petr

;

Korunková, Hana

;

Hora, Milan

;

Kolář, Jiří

;

Šorejs, Ondřej

;

Topolčan, Ondřej

;

Filipovský, Jan

;

Liška, Václav

;

Santoni, Matteo

;

Buti, Sebastiano

;

Fínek, Jindřich

2024

,

Cancer Medicine

,

13

(1)

BACKGROUND: The introduction of novel hormonal therapies represented by enzalutamide (ENZ) and abiraterone acetate (ABI) has reached a great progress in the treatment of metastatic castration-resistant prostate cancer ...

Survival in Thyroid Cancer in Sweden From 1999 To 2018

original article

open access

published version

Zitrický, František

;

Koskinen, Anni

;

Sundquist, Kristina

;

Sundquist, Jan

;

Liška, Václav

;

Försti, Asta

;

Hemminki, Akseli

;

Hemminki, Kari Jussi

2024

,

Clinical Epidemiology

,

16

(2 October 2024)

INTRODUCTION: Thyroid cancer (TC) is diagnosed in several histological types which differ in their clinical characteristics and survival. We aim to describe how they influence TC survival in Sweden. METHODS: Cancer data ...

Small nucleolar RNA expression profiles: A potential prognostic biomarker for non-viral Hepatocellular carcinoma

original article

open access

published version

Mallela, Venkata Ramana

;

Kasi, Phanindra Babu

;

Shetti, Dattatrya

;

Trailin, Andriy

;

Červenková, Lenka

;

Pálek, Richard

;

Daum, Ondřej

;

Liška, Václav

;

Hemminki, Kari Jussi

;

Ambrożkiewicz, Filip

2024

,

Non-coding RNA Research

,

9

(4)

Hepatocellular carcinoma (HCC) is a challenging cancer with high mortality rates, limited predictability, and a lack of effective prognostic indicators. The relationship between small nucleolar RNAs (snoRNAs) and HCC is ...

Unraveling the telomere-mitochondrial axis in colorectal cancer: Results from a prospectively followed cohort

original article

open access

published version

Gil-Korilis, Adrián

;

Ergui-Arbizu, Jorge

;

Hanák, Petr

;

Danešová, Natálie

;

Tomášová, Kristýna

;

Valíčková, Anna

;

Horák, Josef

;

Gentiluomo, Manuel

;

Levý, Miroslav

;

Křivonosková, Soňa

;

Král, Jan

;

Jungwirth, Jiří

;

Vodičková, Ľudmila

;

Vymetálková, Veronika

;

Azqueta, Amaya

;

Campa, Daniele

;

Vodička, Pavel

;

Vodenková, Soňa

2026

,

North Shore-Long Island Jewish Research Institute

,

Molecular Medicine

,

32

(1)

Background Telomere shortening and mitochondrial dysfunction are well-known independent contributors to many diseases, but emerging evidence suggests a reciprocal relationship between the two processes. The role of the ...

Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer

original article

open access

published version

Piccinno, Gianmarco

;

Thompson, Kelsey N.

;

Manghi, Paolo

;

Ghazi, Andrew R.

;

Thomas, Andrew Maltez

;

Blanco-Miguez, Aitor

;

Asnicar, Francesco

;

Mladenovic, Katarina

;

Pinto, Federica

;

Armanini, Federica

;

Puncochar, Michal

;

Piperni, Elisa

;

Heidrich, Vitor

;

Fackelmann, Gloria

;

Ferrero, Giulio

;

Tarallo, Sonia

;

Nguyen, Long H.

;

Yan, Yan

;

Keles, Nazim A.

;

Tuna, Bilge G.

;

Vymetálková, Veronika

;

Trompetto, Mario

;

Liška, Václav

;

Hucl, Tomáš

;

Vodička, Pavel

;

Bencsikova, Beatrix

;

Carnogurska, Martina

;

Popovici, Vlad

;

Marmorino, Federica

;

Cremolini, Chiara

;

Pardini, Barbara

;

Cordero, Francesca

;

Song, Mingyang

;

Chan, Andrew T.

;

Derosa, Lisa

;

Zitvogel, Laurence

;

Huttenhower, Curtis

;

Naccarati, Alessio

;

Budinska, Eva

;

Segata, Nicola

2025

,

Nature Medicine

,

31

(7)

Associations between the gut microbiome and colorectal cancer (CRC) have been uncovered, but larger and more diverse studies are needed to assess their potential clinical use. We expanded upon 12 metagenomic datasets of ...

Native and decellularized porcine vena cava: Histological analysis and in vitro repopulation

original article

open access

published version

Massaro, Maria Stefania

;

Pálek, Richard

;

Malečková, Anna

;

Grajciarová, Martina

;

Červenková, Lenka

;

Polák, Robert

;

Šarčević, Sima

;

Ševčík, Jan

;

Bolek, Lukáš

;

Tonar, Zbyněk

;

Liška, Václav

;

Moulisová, Vladimíra

2025

,

Biomaterials Advances

,

177

(December)

Current standards in vascular reconstruction imply the use of autologous or synthetic material. Despite being standard, autologous grafts are limited by pathologies already affecting the patient and possible complications ...

Native and decellularized porcine vena cava: Biomechanical and microstructural comparison

original article

open access

published version

Massaro, Maria Stefania

;

Sommer, Gerhard

;

Pukaluk, Anna

;

Wolinski, Heimo

;

Pálek, Richard

;

Červenková, Lenka

;

Ševčík, Jan

;

Rampitsch, Katharina

;

Bolek, Lukáš

;

Liška, Václav

;

Holzapfel, Gerhard A

;

Moulisová, Vladimíra

2025

,

Elsevier Ltd.

,

Acta Biomaterialia

,

201

(July)

Tissue decellularization has emerged as a technique to provide an acellular, non-immunogenic scaffold that preserves the morphological features of native tissue. To study the possible effects of decellularization, investigating ...

Anatomical biliary reconstruction as an ultimum refugium for selective cases-History and current state of knowledge

summarizing article

open access

published version

Ševčík, Jan

;

Massaro, Maria Stefania

;

Pálek, Richard

;

Moulisová, Vladimíra

;

Liška, Václav

2024

,

Journal of Hepato-Biliary-Pancreatic Sciences

,

31

(11)

Reconstruction of extrahepatic bile ducts is a staple procedure of HPB surgery. The current standard for most cases is a nonanatomical bilioenteric reconstruction, a satisfactory option for the majority of patients. However, ...

Non-viral HCC miRNA profiling reveals miR-1972 as a potential positive prognostic marker

original article

open access

published version

Mallela, Venkata Ramana

;

Rajtmajerová, Marie

;

Ali, Esraa

;

Červenková, Lenka

;

Trailin, Andriy

;

Hošek, Petr

;

Pálek, Richard

;

Daum, Ondřej

;

Liška, Václav

;

Hemminki, Kari Jussi

;

Ambrożkiewicz, Filip

2025

,

Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

,

Non-coding RNA Research

,

15

(December)

Background & Aims: Hepatocellular carcinoma (HCC) is the third deadliest cancer worldwide. Its high mortality is primarily attributed to late-stage diagnosis. While mutations in driver genes, such as those encoding β-catenin ...

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