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Learning Support Systems: A Practical Guide to E-learning at CU

uncertified methodology

open access

draft

Ovesleová, Hana

;

Posavec-Malok, Dean

;

Javůrková, Jana

;

Polášková, Alexandra

;

Pěnička, Jaroslav

;

Nikl, Tomáš

;

Fuglík, Viktor

;

Švejda, Vít

;

Moravcová, Alžběta

2024

,

Praha

,

Univerzita Karlova, Nakladatelství Karolinum

This guide introduces the e-learning support tools that are used most frequently at Charles University and that you may encounter during your studies. It will also help you to avoid the most common obstacles associated ...

Mitochondrial Transfer Rescues Respiration to Support De Novo Pyrimidine Biosynthesis and Tumor Progression

original article

open access

published version

Dubišová, Mária

;

Boháčová, Klára

;

Nahácka, Zuzana

;

Kraus, Daniel

;

Novák, Jaromír

;

Dvořáková, Šárka

;

Brisudová, Petra

;

Danešová, Natálie

;

Selvi, Saba

;

Hrysiuk, Mariia

;

Endaya, Berwini Beduya

;

Botsios, Panagiotis

;

Le, Thi Dan Diem

;

Novotná, Monika

;

Vodenková, Soňa

;

Truksa, Jaroslav

;

Chalupský, Karel

;

Klíma, Kryštof

;

Procházka, Jan

;

Sedláček, Radislav

;

Mengarelli, Francesco

;

Orlando, Patrick

;

Tiano, Luca

;

Boukalová, Štěpána

;

Berridge, Michael V.

;

Zobalová, Renata

;

Neužil, Jiří

2026

,

American Association for Cancer Research

,

Cancer Research

,

86

(4)

Cancer cells with severe defects in mitochondrial DNA (mtDNA) can import mitochondria via horizontal mitochondrial transfer to restore respiration. Mitochondrial respiration is necessary for the activity of dihydroorotate ...

The Prognostic Role of Baseline and Early Dynamics of Peripheral Blood Cell Ratios in Metastatic Renal Cell Carcinoma Patients Treated With Nivolumab

original article

open access

published version

Fiala, Ondřej

;

Tkadlecová, Michaela

;

Kopecký, Jindřich

;

Hošek, Petr

;

Studentova, Hana

;

Vočka, Michal

;

Matějů, Martin

;

Lohynská, Radka

;

Šiková, Dominika

;

Stránský, Petr

;

Kučera, Radek

;

Zemankova, Anezka

;

Spisarova, Martina

;

Priester, Peter

;

Kouril, Jan

;

Büchler, Tomáš

;

Grmelova, Lucie

;

Melichar, Bohuslav

;

Poprach, Alexandr

2026

,

Iōannīs G. Delīnasios

,

In Vivo

,

40

(2)

BACKGROUND/AIM: Immune checkpoint inhibitors (ICI), including nivolumab, have become the cornerstone of systemic treatment in metastatic renal cell carcinoma (mRCC). Blood-derived biomarkers including neutrophil-to-lymphocyte ...

Comparative analysis of telomere length in peripheral blood of breast cancer BRCA1 mutation carriers and non-carriers

original article

open access

published version

Uttarilli, Anusha

;

Balounová, Kateřina

;

Tomášová, Kristýna

;

Hanak, Petr

;

Šašková, Kateřina

;

Vodička, Pavel

;

Vodičková, Ludmila

;

Hemminki, Kari Jussi

;

Lubinski, Jan

;

Kroupa, Michal

2026

,

Springer

,

Discover Oncology

,

17

(1)

INTRODUCTION: Breast cancer is the most prevalent malignancy among women worldwide. A significant portion of patients possess homologous recombination deficiency (HRD), often caused by BRCA1/2 mutations, which may sensitize ...

Does motherhood increase the risk of developing subsequent malignant neoplasms after childhood cancer treatment?

original article

open access

published version

Blagodárná, Sarah

;

Hošek, Petr

;

Jelínková, Kristýna

;

Korbelová, Lucie

;

Eckschlager, Tomáš

;

Lischke, Robert

;

Šrámková, Lucie

;

Kruseová, Jarmila

2026

,

Elsevier Ltd.

,

Cancer Epidemiology

,

101

(April)

BACKGROUND: Most young women who have survived childhood cancer express a desire to have children. Many of them are concerned about the potential adverse impact of pregnancy on their health, which has been affected by prior ...

Unraveling the telomere-mitochondrial axis in colorectal cancer: Results from a prospectively followed cohort

original article

open access

published version

Gil-Korilis, Adrián

;

Ergui-Arbizu, Jorge

;

Hanák, Petr

;

Danešová, Natálie

;

Tomášová, Kristýna

;

Valíčková, Anna

;

Horák, Josef

;

Gentiluomo, Manuel

;

Levý, Miroslav

;

Křivonosková, Soňa

;

Král, Jan

;

Jungwirth, Jiří

;

Vodičková, Ľudmila

;

Vymetálková, Veronika

;

Azqueta, Amaya

;

Campa, Daniele

;

Vodička, Pavel

;

Vodenková, Soňa

2026

,

North Shore-Long Island Jewish Research Institute

,

Molecular Medicine

,

32

(1)

Background Telomere shortening and mitochondrial dysfunction are well-known independent contributors to many diseases, but emerging evidence suggests a reciprocal relationship between the two processes. The role of the ...

Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer

original article

open access

published version

Piccinno, Gianmarco

;

Thompson, Kelsey N.

;

Manghi, Paolo

;

Ghazi, Andrew R.

;

Thomas, Andrew Maltez

;

Blanco-Miguez, Aitor

;

Asnicar, Francesco

;

Mladenovic, Katarina

;

Pinto, Federica

;

Armanini, Federica

;

Puncochar, Michal

;

Piperni, Elisa

;

Heidrich, Vitor

;

Fackelmann, Gloria

;

Ferrero, Giulio

;

Tarallo, Sonia

;

Nguyen, Long H.

;

Yan, Yan

;

Keles, Nazim A.

;

Tuna, Bilge G.

;

Vymetálková, Veronika

;

Trompetto, Mario

;

Liška, Václav

;

Hucl, Tomáš

;

Vodička, Pavel

;

Bencsikova, Beatrix

;

Carnogurska, Martina

;

Popovici, Vlad

;

Marmorino, Federica

;

Cremolini, Chiara

;

Pardini, Barbara

;

Cordero, Francesca

;

Song, Mingyang

;

Chan, Andrew T.

;

Derosa, Lisa

;

Zitvogel, Laurence

;

Huttenhower, Curtis

;

Naccarati, Alessio

;

Budinska, Eva

;

Segata, Nicola

2025

,

Nature Medicine

,

31

(7)

Associations between the gut microbiome and colorectal cancer (CRC) have been uncovered, but larger and more diverse studies are needed to assess their potential clinical use. We expanded upon 12 metagenomic datasets of ...

Genetic And Environmental Associations Of Nonspecific Chromosomal Aberrations

summarizing article

open access

published version

Hemminki, Kari Jussi

;

Niazi, Yasmeen

;

Vodičková, Ludmila

;

Vodička, Pavel

;

Försti, Asta

2025

,

Mutagenesis

,

40

(1)

Nonspecific structural chromosomal aberrations (CAs) are found in around 1% of circulating lymphocytes from healthy individuals but the frequency may be higher after exposure to carcinogenic chemicals or radiation. CAs ...

Nonprocedural bleeding after left atrial appendage closure versus direct oral anticoagulants: A subanalysis of the randomized PRAGUE-17 trial

original article

open access

published version

Branny, Marian

;

Osmančík, Pavel

;

Kala, Petr

;

Poloczek, Martin

;

Heřman, Dalibor

;

Neužil, Petr

;

Hála, Pavel

;

Táborský, Miloš

;

Šťásek, Josef

;

Haman, Luděk

;

Chovančík, Jan

;

Červinka, Pavel

;

Holý, Jiří

;

Kovárník, Tomáš

;

Zemánek, David

;

Havránek, Štěpán

;

Vančura, Vlastimil

;

Peichl, Petr

;

Toušek, Petr

;

Hozman, Marek

;

Lekešová, Veronika

;

Jarkovský, Jiří

;

Nováčková, Martina

;

Benešová, Klára

;

Widimský, Petr

;

Reddy, Vivek Y

2023

,

Journal of Cardiovascular Electrophysiology

,

34

(9)

INTRODUCTION: Observational studies have shown low bleeding rates in patients with atrial fibrillation (AF) treated by left atrial appendage closure (LAAC); however, data from randomized studies are lacking. This study ...

Polymorphisms in transcription factor binding sites and enhancer regions and pancreatic ductal adenocarcinoma risk

original article

open access

published version

Ünal, Pelin

;

Lu, Ye

;

Bueno-de-Mesquita, Bas

;

van Eijck, Casper H. J.

;

Talar-Wojnarowska, Renata

;

Szentesi, Andrea

;

Gazouli, Maria

;

Kreivenaite, Edita

;

Tavano, Francesca

;

Małecka-Wojciesko, Ewa

;

Erőss, Bálint

;

Oliverius, Martin

;

Bunduc, Stefania

;

Nóbrega Aoki, Mateus

;

Vodičková, Ludmila

;

Boggi, Ugo

;

Giaccherini, Matteo

;

Kondrackiene, Jurate

;

Chammas, Roger

;

Palmieri, Orazio

;

Theodoropoulos, George E.

;

Bijlsma, Maarten F.

;

Basso, Daniela

;

Mohelníková-Duchoňová, Beatrice

;

Souček, Pavel

;

Izbicki, Jakob R

;

Kiudelis, Vytautas

;

Vanella, Giuseppe

;

Arcidiacono, Paolo Giorgio

;

Włodarczyk, Barbara

;

Hackert, Thilo

;

Schöttker, Ben

;

Uzunoglu, Faik G.

;

Bambi, Franco

;

Goetz, Mara

;

Hlaváč, Viktor

;

Brenner, Hermann

;

Perri, Francesco

;

Carrara, Silvia

;

Landi, Stefano

;

Hegyi, Péter

;

Dijk, Frederike

;

Maiello, Evaristo

;

Capretti, Giovanni

;

Testoni, Sabrina Gloria Giulia

;

Petrone, Maria Chiara

;

Stocker, Hannah

;

Ermini, Stefano

;

Archibugi, Livia

;

Gentiluomo, Manuel

;

Cavestro, Giulia Martina

;

Pezzilli, Raffaele

;

Di Franco, Gregorio

;

Milanetto, Anna Caterina

;

Sperti, Cosimo

;

Neoptolemos, John P.

;

Morelli, Luca

;

Vokáčová, Klára

;

Pasquali, Claudio

;

Lawlor, Rita T

;

Bazzocchi, Francesca

;

Kupcinskas, Juozas

;

Capurso, Gabriele

;

Campa, Daniele

;

Canzian, Federico

2024

,

Henry Stewart Publications

,

Human Genomics

,

18

(February)

Genome-wide association studies (GWAS) are a powerful tool for detecting variants associated with complex traits and can help risk stratification and prevention strategies against pancreatic ductal adenocarcinoma (PDAC). ...

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