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Sclerosing mucoepidermoid carcinoma of salivary glands

original article

open access

published version

Othman, Bacem Abdullah Essam Othman Khalele

;

Bradová, Martina

;

Simpson, Roderick H W

;

Laco, Jan

;

Agaimy, Abbas

;

Rito, Miguel

;

Ihrler, Stephan

;

Steiner, Petr

;

Grossmann, Petr

;

Hájková, Veronika

;

de Rezende, Gisele

;

Goma, Montse

;

Koljenovic, Senada

;

Fonseca, Isabel

;

Michal, Michal

;

Leivo, Ilmo

;

Skálová, Alena

2025

,

Springer

,

Virchows Archiv

,

487

(1)

Sclerosing mucoepidermoid carcinoma (SMEC) of the salivary glands is a rare variant of low-grade mucoepidermoid carcinoma with scanty cellular atypia characterized by marked fibrosis/sclerosis and a rich inflammatory ...

Sinonasal adenosquamous carcinomas arising in seromucinous hamartoma or respiratory epithelial adenomatoid hamartoma with atypical features: Report of five detailed clinicopathological and molecular characterisation of rare entity

original article

open access

published version

Bradová, Martina

;

Costes-Martineau, Valerie

;

Laco, Jan

;

Vaněček, Tomáš

;

Grossmann, Petr

;

Němcová, Jana

;

Pavlovský, Zdeněk

;

Skálová, Alena

;

Michal, Michal

2025

,

Blackwell Science

,

Histopathology

,

86

(4)

AIMS: Sinonasal adenosquamous carcinoma (ASC) is a rare tumour classified as a variant of squamous cell carcinoma, exhibiting both squamous and glandular differentiation. ASC has a poorer prognosis compared to sinonasal ...

Sinonasal adenoid cystic carcinomas accompanied by seromucinous hamartoma and/or atypical sinonasal glands arising from seromucinous hamartoma: insight into their histogenesis

original article

open access

published version

Bradová, Martina

;

Agaimy, Abbas

;

Laco, Jan

;

Martínek, Petr

;

Kormunda, Stanislav

;

Badoual, Cécile

;

Damjanov, Ivan

;

Leivo, Ilmo

;

Bacchi, Carlos E.

;

Comperat, Eva

;

Ihrler, Stephan

;

Rupp, Niels J.

;

Šíma, Radek

;

Šteiner, Petr

;

Vaněček, Tomáš

;

Mueller, Sarina

;

Ventelä, Sami

;

Skálová, Alena

;

Michal, Michal

2025

,

Springer

,

Virchows Archiv

,

486

(6)

The pathology of reactive, dysplastic, and neoplastic sinonasal seromucinous glands is complex, and their contribution to tumorigenesis of sinonasal carcinomas remains controversial. In our practice, we have observed the ...

Basal cell adenoma with S100 protein-positive "stroma": a distinct triphasic salivary gland neoplasm characterized by CTNNB1 mutation

original article

open access

published version

Skálová, Alena

;

Bradová, Martina

;

Laco, Jan

;

Vaněček, Tomáš

;

Hájková, Veronika

;

Martínek, Petr

;

Grendár, Marián

;

Querzoli, Giulia

;

Leivo, Ilmo

;

Michal, Michal

2026

,

Springer

,

Virchows Archiv

,

488

(2)

Basal cell adenoma (BCA) is a benign salivary neoplasm that exhibits a divergent spectrum of growth patterns, including cribriform, tubular, trabecular, membranous, and solid. A subset of BCAs is characterized by the ...

The Prognostic Role of Baseline and Early Dynamics of Peripheral Blood Cell Ratios in Metastatic Renal Cell Carcinoma Patients Treated With Nivolumab

original article

open access

published version

Fiala, Ondřej

;

Tkadlecová, Michaela

;

Kopecký, Jindřich

;

Hošek, Petr

;

Studentova, Hana

;

Vočka, Michal

;

Matějů, Martin

;

Lohynská, Radka

;

Šiková, Dominika

;

Stránský, Petr

;

Kučera, Radek

;

Zemankova, Anezka

;

Spisarova, Martina

;

Priester, Peter

;

Kouril, Jan

;

Büchler, Tomáš

;

Grmelova, Lucie

;

Melichar, Bohuslav

;

Poprach, Alexandr

2026

,

Iōannīs G. Delīnasios

,

In Vivo

,

40

(2)

BACKGROUND/AIM: Immune checkpoint inhibitors (ICI), including nivolumab, have become the cornerstone of systemic treatment in metastatic renal cell carcinoma (mRCC). Blood-derived biomarkers including neutrophil-to-lymphocyte ...

Molecular Profiling of Sinonasal Adenoid Cystic Carcinoma: Canonical and Noncanonical Gene Fusions and Mutation

original article

open access

published version

Skálová, Alena

;

Bradová, Martina

;

Agaimy, Abbas

;

Laco, Jan

;

Badual, Cécile

;

Ihrler, Stephan

;

Damjanov, Ivan

;

Rupp, Niels J.

;

Bacchi, Carlos E.

;

Mueller, Sarina

;

Ventelä, Sami

;

Zhang, Da

;

Comperat, Eva

;

Martínek, Petr

;

Šíma, Radek

;

Vaněček, Tomáš

;

Grossmann, Petr

;

Šteiner, Petr

;

Hájková, Veronika

;

Kovářová, Inka

;

Michal, Michal

;

Leivo, Ilmo

2025

,

Lippincott-Raven Publishers

,

American Journal of Surgical Pathology

,

49

(3)

Adenoid cystic carcinomas (AdCC) of salivary gland origin have long been categorized as fusion-defined carcinomas owing to the almost universal presence of the gene fusion MYB::NFIB, or less commonly MYBL1::NFIB. Sinonasal ...

Nonprocedural bleeding after left atrial appendage closure versus direct oral anticoagulants: A subanalysis of the randomized PRAGUE-17 trial

original article

open access

published version

Branny, Marian

;

Osmančík, Pavel

;

Kala, Petr

;

Poloczek, Martin

;

Heřman, Dalibor

;

Neužil, Petr

;

Hála, Pavel

;

Táborský, Miloš

;

Šťásek, Josef

;

Haman, Luděk

;

Chovančík, Jan

;

Červinka, Pavel

;

Holý, Jiří

;

Kovárník, Tomáš

;

Zemánek, David

;

Havránek, Štěpán

;

Vančura, Vlastimil

;

Peichl, Petr

;

Toušek, Petr

;

Hozman, Marek

;

Lekešová, Veronika

;

Jarkovský, Jiří

;

Nováčková, Martina

;

Benešová, Klára

;

Widimský, Petr

;

Reddy, Vivek Y

2023

,

Journal of Cardiovascular Electrophysiology

,

34

(9)

INTRODUCTION: Observational studies have shown low bleeding rates in patients with atrial fibrillation (AF) treated by left atrial appendage closure (LAAC); however, data from randomized studies are lacking. This study ...

Outcomes Of Patients With Myocardial Infarction And Cardiogenic Shock Treated With Culprit Vessel-Only Versus Multivessel Primary PCI

original article

open access

published version

Hlinomaz, Ota

;

Moťovská, Zuzana

;

Kala, Petr

;

Hromádka, Milan

;

Přeček, Jan

;

Mrózek, Jan

;

Červinka, Pavel

;

Kettner, Jiří

;

Matějka, Jan

;

Zohoor, Ahmad

;

Bis, Josef

;

Jarkovský, Jiří

2024

,

Hellenic Journal of Cardiology

,

76

(MAR-APR)

INTRODUCTION AND OBJECTIVES: Multivessel primary percutaneous coronary intervention (pPCI) is still often used in patients with ST-elevation myocardial infarction (STEMI) and cardiogenic shock (CS). The study aimed to ...

The Czech National MS Registry (ReMuS): Data trends in multiple sclerosis patients whose first disease-modifying therapies were initiated from 2013 to 2021

original article

open access

published version

Šťastná, Dominika

;

Drahota, Jiří

;

Lauer, Michal

;

Mazouchová, Aneta

;

Meňkyová, Ingrid

;

Adámková, Jana

;

Ampapa, Radek

;

Dufek, Michal

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Grunermelova, Marketa

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Hradilek, Pavel

;

Kubala Havrdová, Eva

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Mareš, Jan

;

Martínková, Alena

;

Pavelek, Zbyšek

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Peterka, Marek

;

Recmanová, Eva

;

Ročková, Petra

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Štětkářová, Ivana

;

Štourač, Pavel

;

Vachová, Marta

;

Horáková, Dana

2024

,

Palacký University

,

Biomedical Papers

,

168

(3)

AIMS: Multiple sclerosis treatment strategies are changing in the Czech Republic. According to data from 2013-2021, the proportion of patients starting high-efficacy disease-modifying therapies is increasing. In this survey, ...

Pembrolizumab versus Pembrolizumab plus Chemotherapy in Non-small Cell Lung Cancer with High PD-L1 Expression - Multicenter Real-world Evidence Study

original article

open access

published version

Svatoň, Martin

;

Knetki-Wroblewska, Magdalena

;

Hošek, Petr

;

Chowaniecova, Gabriela

;

Špaček, Jan

;

Fischer, Ondřej

;

Bílek, Ondřej

;

Hrnčiarik, Michal

;

Kauffmann-Guerrero, Diego

2025

,

Ivyspring International Publisher

,

Journal of Cancer

,

16

(10)

Background: Patients with non-small cell lung cancer (NSCLC) with PD-Ll expression ~ 50% can be treated with immunotherapy alone or with a combination of immunotherapy and chemotherapy. One of these options is treatment ...

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