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Small nucleolar RNA expression profiles: A potential prognostic biomarker for non-viral Hepatocellular carcinoma

original article

open access

published version

Mallela, Venkata Ramana

;

Kasi, Phanindra Babu

;

Shetti, Dattatrya

;

Trailin, Andriy

;

Červenková, Lenka

;

Pálek, Richard

;

Daum, Ondřej

;

Liška, Václav

;

Hemminki, Kari Jussi

;

Ambrożkiewicz, Filip

2024

,

Non-coding RNA Research

,

9

(4)

Hepatocellular carcinoma (HCC) is a challenging cancer with high mortality rates, limited predictability, and a lack of effective prognostic indicators. The relationship between small nucleolar RNAs (snoRNAs) and HCC is ...

Emerging Role of Circulating Cell-Free RNA as a Non-Invasive Biomarker for Hepatocellular Carcinoma

original article

open access

published version

Shetti, Dattatrya

;

Mallela, Venkata Ramana

;

Ye, Wenjing

;

Sharif Bagheri, Mahyar

;

Ambrożkiewicz, Filip

;

Trailin, Andriy

;

Liška, Václav

;

Hemminki, Kari Jussi

2024

,

Critical Reviews in Oncology/Hematology

,

200

(August)

Hepatocellular carcinoma (HCC) is a severe neoplastic disease associated with high morbidity and mortality rates. HCC is often detected at advanced stages leading to ineffective curative treatments. Recently, liquid biopsy ...

Concomitant antihypertensive medication and outcome of patients with metastatic castration-resistant prostate cancer receiving enzalutamide or abiraterone acetate

original article

open access

published version

Fiala, Ondřej

;

Hošek, Petr

;

Korunková, Hana

;

Hora, Milan

;

Kolář, Jiří

;

Šorejs, Ondřej

;

Topolčan, Ondřej

;

Filipovský, Jan

;

Liška, Václav

;

Santoni, Matteo

;

Buti, Sebastiano

;

Fínek, Jindřich

2024

,

Cancer Medicine

,

13

(1)

BACKGROUND: The introduction of novel hormonal therapies represented by enzalutamide (ENZ) and abiraterone acetate (ABI) has reached a great progress in the treatment of metastatic castration-resistant prostate cancer ...

Genomic characterization of ST38 NDM-5-producing Escherichia coli isolates from an outbreak in the Czech Republic

original article

open access

accepted version

Chudějová, Kateřina

;

Sourenian-Samuelian, Tsolaire

;

Palkovičová, Jana

;

Stredanska, Katarina

;

Nechutná, Lucie

;

Vlková, Kateřina

;

Heringová, Vendula

;

Papagiannitsis, Costas C.

;

Hrabák, Jaroslav

;

Dolejská, Monika

;

Bitar, Ibrahim

2024

,

Antimicrobial Agents and Chemotherapy

,

68

(6)

A 2-year national genomic screening in the Czech Republic identified a notable prevalence of the New Delhi metallo-β-lactamase 5 (NDM-5)-producing Escherichia coli sequence type 38 (ST38) in the city of Brno. Forty-two ...

A novel F type plasmid encoding mcr-10 in a clinical Enterobacter ludwigii strain from a tertiary hospital in Czech Republic

original article

open access

published version

Sourenian-Samuelian, Tsolaire

;

Palkovičová, Jana

;

Papagiannitsis, Costas

;

Dolejská, Monika

;

Hrabák, Jaroslav

;

Bitar, Ibrahim

2024

,

Journal of Global Antimicrobial Resistance

,

37

(June)

Objective: Here we describe a novel IncFIA plasmid harboring mcr-10 gene in a clinical Enterobacter ludwigii strain isolated at the University Hospital in Pilsen in the Czech Republic.Methods: The strain was subjected to ...

Molecular characterization of carbapenem and ceftazidime-avibactam-resistant Enterobacterales and horizontal spread of bla_NDM-5 gene at a Lebanese medical center

original article

open access

published version

Sobh, Ghena

;

Araj, George F.

;

Finianos, Marc

;

Sourenian-Samuelian, Tsolaire

;

Hrabák, Jaroslav

;

Papagiannitsis, Costas C.

;

Chaar, Mira El

;

Bitar, Ibrahim

2024

,

Frontiers in Cellular and Infection Microbiology

,

14

(19 June 2024)

Introduction: In the battle against multidrug-resistant bacterial infections, ceftazidime- avibactam (CZA) stands as a pivotal defense, particularly against carbapenemresistant (CR) Gram-negative pathogens. However, the ...

Understanding the value of monocyte distribution width (MDW) in acutely ill medical patients presenting to the emergency department: a prospective single center evaluation

original article

open access

published version

Královcová, Marcela

;

Müller, Jiří

;

Hajšmanová, Zdeňka

;

Šigutová, Pavla

;

Bultasová, Lenka

;

Palátová, Jana

;

Matějovič, Martin

2024

,

Scientific Reports

,

14

(02 July 2024)

The monocyte distribution width (MDW) has emerged as a promising biomarker for accurate and early identification of patients with potentially life-threatening infections. Here we tested the diagnostic performance of MDW ...

Giant Cell Temporal Arteritis Followed by Severe Encephalopathy Induced by Immunotherapy in a Patient with Metastatic Renal Cell Carcinoma Achieving Durable Partial Response: A Case Report

casuistics

open access

published version

Fiala, Ondřej

;

Tkadlecová, Michaela

;

Pivovarčíková, Kristýna

;

Baxa, Jan

;

Stránský, Petr

;

Šiková, Dominika

;

Hora, Milan

;

Fínek, Jindřich

2024

,

Case Reports in Oncology

,

17

(1)

Introduction: Combined immuno-oncology (IO) regimens are the cornerstone of the current front-line systemic therapy for metastatic renal cell carcinoma (mRCC). Despite the fact that combined IO regimens show high efficacy, ...

Secukinumab Causing Medication-Related Osteonecrosis of the Jaw, in a Patient Diagnosed with Psoriasis and Rheumatoid Arthritis

casuistics

open access

published version

Hauer, Lukáš

;

Moztarzadeh, Omid

;

Baghalipour, Nasimeh

;

Genčur, Jiří

2024

,

Psoriasis

,

14

(23 September 2024)

The use of antiangiogenic and antiresorptive medications, particularly in patients with cancer or osteoporosis, can lead to osteonecrosis of the jaw following tooth extraction, trauma or arising spontaneously- A condition ...

Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer

original article

open access

published version

Piccinno, Gianmarco

;

Thompson, Kelsey N.

;

Manghi, Paolo

;

Ghazi, Andrew R.

;

Thomas, Andrew Maltez

;

Blanco-Miguez, Aitor

;

Asnicar, Francesco

;

Mladenovic, Katarina

;

Pinto, Federica

;

Armanini, Federica

;

Puncochar, Michal

;

Piperni, Elisa

;

Heidrich, Vitor

;

Fackelmann, Gloria

;

Ferrero, Giulio

;

Tarallo, Sonia

;

Nguyen, Long H.

;

Yan, Yan

;

Keles, Nazim A.

;

Tuna, Bilge G.

;

Vymetálková, Veronika

;

Trompetto, Mario

;

Liška, Václav

;

Hucl, Tomáš

;

Vodička, Pavel

;

Bencsikova, Beatrix

;

Carnogurska, Martina

;

Popovici, Vlad

;

Marmorino, Federica

;

Cremolini, Chiara

;

Pardini, Barbara

;

Cordero, Francesca

;

Song, Mingyang

;

Chan, Andrew T.

;

Derosa, Lisa

;

Zitvogel, Laurence

;

Huttenhower, Curtis

;

Naccarati, Alessio

;

Budinska, Eva

;

Segata, Nicola

2025

,

Nature Medicine

,

31

(7)

Associations between the gut microbiome and colorectal cancer (CRC) have been uncovered, but larger and more diverse studies are needed to assess their potential clinical use. We expanded upon 12 metagenomic datasets of ...

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