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Small nucleolar RNA expression profiles: A potential prognostic biomarker for non-viral Hepatocellular carcinoma 

original article

open access

published version

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Mallela, Venkata Ramana

;

Kasi, Phanindra Babu

;

Shetti, Dattatrya

;

Trailin, Andriy

;

Červenková, Lenka

;

Pálek, Richard

;

Daum, Ondřej

;

Liška, Václav

;

Hemminki, Kari Jussi

;

Ambrożkiewicz, Filip

2024

,

Non-coding RNA Research

,

9

(4)

Hepatocellular carcinoma (HCC) is a challenging cancer with high mortality rates, limited predictability, and a lack of effective prognostic indicators. The relationship between small nucleolar RNAs (snoRNAs) and HCC is ...

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Emerging Role of Circulating Cell-Free RNA as a Non-Invasive Biomarker for Hepatocellular Carcinoma 

original article

open access

published version

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Shetti, Dattatrya

;

Mallela, Venkata Ramana

;

Ye, Wenjing

;

Sharif Bagheri, Mahyar

;

Ambrożkiewicz, Filip

;

Trailin, Andriy

;

Liška, Václav

;

Hemminki, Kari Jussi

2024

,

Critical Reviews in Oncology/Hematology

,

200

(August)

Hepatocellular carcinoma (HCC) is a severe neoplastic disease associated with high morbidity and mortality rates. HCC is often detected at advanced stages leading to ineffective curative treatments. Recently, liquid biopsy ...

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Concomitant antihypertensive medication and outcome of patients with metastatic castration-resistant prostate cancer receiving enzalutamide or abiraterone acetate 

original article

open access

published version

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Fiala, Ondřej

;

Hošek, Petr

;

Korunková, Hana

;

Hora, Milan

;

Kolář, Jiří

;

Šorejs, Ondřej

;

Topolčan, Ondřej

;

Filipovský, Jan

;

Liška, Václav

;

Santoni, Matteo

;

Buti, Sebastiano

;

Fínek, Jindřich

2024

,

Cancer Medicine

,

13

(1)

BACKGROUND: The introduction of novel hormonal therapies represented by enzalutamide (ENZ) and abiraterone acetate (ABI) has reached a great progress in the treatment of metastatic castration-resistant prostate cancer ...

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Survival in Thyroid Cancer in Sweden From 1999 To 2018 

original article

open access

published version

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Zitrický, František

;

Koskinen, Anni

;

Sundquist, Kristina

;

Sundquist, Jan

;

Liška, Václav

;

Försti, Asta

;

Hemminki, Akseli

;

Hemminki, Kari Jussi

2024

,

Clinical Epidemiology

,

16

(2 October 2024)

INTRODUCTION: Thyroid cancer (TC) is diagnosed in several histological types which differ in their clinical characteristics and survival. We aim to describe how they influence TC survival in Sweden. METHODS: Cancer data ...

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Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer 

original article

open access

published version

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Piccinno, Gianmarco

;

Thompson, Kelsey N.

;

Manghi, Paolo

;

Ghazi, Andrew R.

;

Thomas, Andrew Maltez

;

Blanco-Miguez, Aitor

;

Asnicar, Francesco

;

Mladenovic, Katarina

;

Pinto, Federica

;

Armanini, Federica

;

Puncochar, Michal

;

Piperni, Elisa

;

Heidrich, Vitor

;

Fackelmann, Gloria

;

Ferrero, Giulio

;

Tarallo, Sonia

;

Nguyen, Long H.

;

Yan, Yan

;

Keles, Nazim A.

;

Tuna, Bilge G.

;

Vymetálková, Veronika

;

Trompetto, Mario

;

Liška, Václav

;

Hucl, Tomáš

;

Vodička, Pavel

;

Bencsikova, Beatrix

;

Carnogurska, Martina

;

Popovici, Vlad

;

Marmorino, Federica

;

Cremolini, Chiara

;

Pardini, Barbara

;

Cordero, Francesca

;

Song, Mingyang

;

Chan, Andrew T.

;

Derosa, Lisa

;

Zitvogel, Laurence

;

Huttenhower, Curtis

;

Naccarati, Alessio

;

Budinska, Eva

;

Segata, Nicola

2025

,

Nature Medicine

,

31

(7)

Associations between the gut microbiome and colorectal cancer (CRC) have been uncovered, but larger and more diverse studies are needed to assess their potential clinical use. We expanded upon 12 metagenomic datasets of ...

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Native and decellularized porcine vena cava: Histological analysis and in vitro repopulation 

original article

open access

published version

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Massaro, Maria Stefania

;

Pálek, Richard

;

Malečková, Anna

;

Grajciarová, Martina

;

Červenková, Lenka

;

Polák, Robert

;

Šarčević, Sima

;

Ševčík, Jan

;

Bolek, Lukáš

;

Tonar, Zbyněk

;

Liška, Václav

;

Moulisová, Vladimíra

2025

,

Biomaterials Advances

,

177

(December)

Current standards in vascular reconstruction imply the use of autologous or synthetic material. Despite being standard, autologous grafts are limited by pathologies already affecting the patient and possible complications ...

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Native and decellularized porcine vena cava: Biomechanical and microstructural comparison 

original article

open access

published version

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Massaro, Maria Stefania

;

Sommer, Gerhard

;

Pukaluk, Anna

;

Wolinski, Heimo

;

Pálek, Richard

;

Červenková, Lenka

;

Ševčík, Jan

;

Rampitsch, Katharina

;

Bolek, Lukáš

;

Liška, Václav

;

Holzapfel, Gerhard A

;

Moulisová, Vladimíra

2025

,

Elsevier Ltd.

,

Acta Biomaterialia

,

201

(July)

Tissue decellularization has emerged as a technique to provide an acellular, non-immunogenic scaffold that preserves the morphological features of native tissue. To study the possible effects of decellularization, investigating ...

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Anatomical biliary reconstruction as an ultimum refugium for selective cases-History and current state of knowledge 

summarizing article

open access

published version

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Ševčík, Jan

;

Massaro, Maria Stefania

;

Pálek, Richard

;

Moulisová, Vladimíra

;

Liška, Václav

2024

,

Journal of Hepato-Biliary-Pancreatic Sciences

,

31

(11)

Reconstruction of extrahepatic bile ducts is a staple procedure of HPB surgery. The current standard for most cases is a nonanatomical bilioenteric reconstruction, a satisfactory option for the majority of patients. However, ...

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Non-viral HCC miRNA profiling reveals miR-1972 as a potential positive prognostic marker 

original article

open access

published version

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Mallela, Venkata Ramana

;

Rajtmajerová, Marie

;

Ali, Esraa

;

Červenková, Lenka

;

Trailin, Andriy

;

Hošek, Petr

;

Pálek, Richard

;

Daum, Ondřej

;

Liška, Václav

;

Hemminki, Kari Jussi

;

Ambrożkiewicz, Filip

2025

,

Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

,

Non-coding RNA Research

,

15

(December)

Background & Aims: Hepatocellular carcinoma (HCC) is the third deadliest cancer worldwide. Its high mortality is primarily attributed to late-stage diagnosis. While mutations in driver genes, such as those encoding β-catenin ...

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Macrophages in Colorectal Cancer: From Normal Mucosa to Distant Metastasis: Beyond the M1/M2 Paradigm 

summarizing article

open access

submitted version

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Pavlov, Sergii

;

Sobhe Abdelhamid Mahmoud, Esraa

;

Ambrożkiewicz, Filip

;

Ye, Wenjing

;

Rajtmajerová, Marie

;

Liška, Václav

;

Hemminki, Kari Jussi

;

Trailin, Andriy

2025

,

Ivyspring International Publisher

,

Journal of Cancer

,

17

(1)

Colorectal cancer (CRC) is the third most common malignancy and a leading cause of mortality worldwide. The tumor microenvironment (TME) strongly influences CRC growth, immune evasion, and metastasis. Among various immune ...

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Research Output Typejournal article (19)... View MoreDate Issued2025 (9)2024 (6)2026 (3)2023 (1)Faculty / University unitFaculty of Medicine in Pilsen (19)University Hospital in Pilsen (7)First Faculty of Medicine (3)Faculty of Science (2)Second Faculty of Medicine (2)Department / Institute / Clinic
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