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Long Non-Coding RNA and microRNA Interplay in Colorectal Cancer and Their Effect on the Tumor Microenvironment

summarizing article

embargoed access

published version

Rajtmajerová, Marie

;

Trailin, Andriy

;

Liška, Václav

;

Hemminki, Kari Jussi

;

Ambrożkiewicz, Filip

2022

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Cancers

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14

(21)

As the current staging and grading systems are not sufficient to stratify patients for therapy and predict the outcome of the disease, there is an urgent need to understand cancer in its complexity. The mutual relationship ...

Gut Microbiome Diversity of Porcine Peritonitis Model of Sepsis

abstract in conference proceedings

embargoed access

published version

Chalupová, Miroslava

;

Horák, Jan

;

Kramná, Lenka

;

Nalos, Lukáš

;

Štengl, Milan

;

Chudějová, Kateřina

;

Kraftová, Lucie

;

Cinek, Ondřej

;

Klein, Pavel

;

Matějovič, Martin

;

Hrabák, Jaroslav

2022

,

Czech Chemical Society Symposium Series

,

20

(6)

Animal models are essential in understanding of the mechanisms of sepsis moreover the development and the assessment of emerging therapies. In clinically relevant porcine model, however, a significant ...

Red fox (Vulpes vulpes) play an important role in the propagation of tick-borne pathogens

original article

open access

published version

Lesiczka, Paulina Maria

;

Rudenko, Natalia

;

Golovchenko, Maryna

;

Juránková, Jana

;

Daněk, Ondřej

;

Modrý, David

;

Hrazdilová, Kristýna

2023

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Ticks and Tick-Borne Diseases

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14

(1)

The red fox (Vulpes vulpes) is the most widespread free-living carnivore in the world. Over the years, foxes have been recognized as hosts for a number of tick-borne pathogens. However, their role as reservoirs for zoonotic ...

Distant genetic variants of Anaplasma phagocytophilum from Ixodes ricinus attached to people

original article

embargoed access

published version

Lesiczka, Paulina Maria

;

Hrazdilová, Kristýna

;

Hönig, Václav

;

Modrý, David

;

Zurek, Ludek

2023

,

Parasites & Vectors

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16

(1)

Background: Although the tick-borne pathogen Anaplasma phagocytophilum is currently described as a single species, studies using genetic markers can distinguish groups of variants associated with different hosts, pathogenicity, ...

Personal comorbidities and their subsequent risks for liver, gallbladder and bile duct cancers

original article

open access

published version

Hemminki, Kari Jussi

;

Sundquist, Kristina

;

Sundquist, Jan

;

Foersti, Asta

;

Liška, Václav

;

Hemminki, Akseli

;

Li, Xinjun

2023

,

International Journal of Cancer

,

152

(6)

Many environmental risk factors for hepatobiliary cancers are known but whether they are associated with specific cancer types is unclear. We present here a novel approach of assessing standardized incidence ratios (SIRs) ...

Whole Exome Sequencing of Epithelial Ovarian Carcinomas Differing in Resistance to Platinum Therapy

original article

embargoed access

published version

Hlaváč, Viktor

;

Holý, Petr

;

Václavíková, Radka

;

Rob, Lukáš

;

Hruda, Martin

;

Mrhalová, Marcela

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Černaj, Petr

;

Bouda, Jiří

;

Souček, Pavel

2022

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Life Science Alliance

,

5

(12)

Epithelial ovarian carcinoma (EOC) is highly fatal because of the risk of resistance to therapy and recurrence. We performed whole-exome sequencing of blood and tumor tissue pairs of 50 patients with surgically resected ...

O čem také přemýšlejí naši medici. Sborník studentských prací (2023)

Thoughts of medical students. Collection of written projects (2023)

collection of papers

open access

published version

Vevera, Jan

;

Pišl, Vojtěch

;

Fridrich, Dominik

;

Miloschewská, Natalie

;

Bednářová, Sofie

;

Bernklauová, Adriana

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Brejníková, Laura

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El Mahmoudi, Nadia

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Franková, Barbora

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Lásková, Lucie

;

Loukotová, Adéla

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Malá, Nicole

;

Manten, Theresa

;

Pennartz, Sebastian

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Randa, Tomáš

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Salteri, Myrto Zoi

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Siebold, Patricia Sophie

;

Vulliet, Lison

2023

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Plzeň

,

Psychiatrická klinika, Lékařská fakulta v Plzni Univerzity Karlovy

Výbor nejlepších esejí, které odevzdali studenti Lékařské fakulty Univerzity Karlovy v Plzni v akademickém roce 2022/2023 v rámci předmětu Lékařská psychologie a etika.

Serum Metabolite Biomarkers for Pancreatic Tumors: Neuroendocrine and Pancreatic Ductal Adenocarcinomas-A Preliminary Study

original article

open access

published version

Skubisz, Karolina

;

Dąbkowski, Krzysztof

;

Samborowska, Emilia

;

Starzyńska, Teresa

;

Deskur, Anna

;

Ambrożkiewicz, Filip

;

Karczmarski, Jakub

;

Radkiewicz, Mariusz

;

Kusnierz, Katarzyna

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Kos-Kudła, Beata

;

Sulikowski, Tadeusz

;

Cybula, Patrycja

;

Paziewska, Agnieszka

2023

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Cancers

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15

(12)

BACKGROUND: Pancreatic cancer is the most common pancreatic solid malignancy with an aggressive clinical course and low survival rate. There are a limited number of reliable prognostic biomarkers and a need to understand ...

Gut microbiome diversity of porcine peritonitis model of sepsis

original article

embargoed access

published version

Chalupová, Miroslava

;

Horák, Jan

;

Kramná, Lenka

;

Nalos, Lukáš

;

Štengl, Milan

;

Chudějová, Kateřina

;

Kraftová, Lucie

;

Cinek, Ondřej

;

Klein, Pavel

;

Matějovič, Martin

;

Hrabák, Jaroslav

2022

,

Scientific Reports

,

12

(1)

Animal models are essential in understanding of the mechanisms of sepsis moreover the development and the assessment of emerging therapies. In clinically relevant porcine model, however, a significant variability in the ...

Polyclonal Spread of Fosfomycin Resistance among Carbapenemase-Producing Members of the Enterobacterales in the Czech Republic

original article

embargoed access

accepted version

Mattioni Marchetti, Vittoria

;

Kraftová, Lucie

;

Finianos, Marc

;

Sourenian-Samuelian, Tsolaire

;

Hrabák, Jaroslav

;

Bitar, Ibrahim

2023

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Microbiology spectrum

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11

(3)

Fosfomycin (FOS) has been recently reintroduced into clinical practice, but its effectiveness against multidrug-resistant (MDR) Enterobacterales is reduced due to the emergence of FOS resistance. The copresence of ...

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