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Percutaneous transthoracic needle biopsy of lung lesions is a safe method associated with a very low risk of pleural recurrence 

original article

open access

published version

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Svatoň, Martin

;

Havel, David

;

Burešová, Marcela

;

Baxa, Jan

;

Hošek, Petr

2025

,

Biomedical Papers

,

169

(1)

AIM: Percutaneous transthoracic needle biopsy (PTNB), an alternative to bronchoscopic confirmation of lung lesions, is today being associated with a risk of pneumothorax and hemorrhage. Further, there are no data on the ...

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Prognostic Role of Prostate-specific Antigen Isoforms and Their Early Kinetics in Patients With Metastatic Castration-resistant Prostate Cancer Receiving New Generation Androgen Receptor Targeted Agents 

original article

open access

published version

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Fiala, Ondřej

;

Hošek, Petr

;

Korunková, Hana

;

Tkadlecová, Michaela

;

Hora, Milan

;

Šiková, Dominika

;

Stránský, Petr

;

Fínek, Jindřich

;

Kučera, Radek

;

Windrichová, Jindra

;

Topolčan, Ondřej

2025

,

Iōannīs G. Delīnasios

,

In Vivo

,

39

(2)

BACKGROUND/AIM: New generation androgen receptor-targeting agents (ARTA) have been in the spotlight for their efficacy in metastatic castration-resistant prostate cancer (mCRPC). Prostate-specific antigen (PSA) represents ...

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Oral presentation of paraneoplastic pemphigus as the first sign of tonsillar HPV associated squamous cell carcinoma. A case report 

casuistics

open access

published version

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Liška, Jan

;

Lišková, Veronika

;

Trčka, Ondřej

;

Ondič, Ondrej

;

Hauer, Lukáš

;

Baxa, Jan

;

Kacerovská, Denisa

2022

,

Biomedical Papers

,

166

(4)

Background: Paraneoplastic pemphigus (PNP) in the oral cavity is a rare variant of blistering pemphigus disease closely associated with mostly malignant tumors. The diagnosis may even precede an underlying malignancy ...

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Anatomical biliary reconstruction as an ultimum refugium for selective cases-History and current state of knowledge 

summarizing article

open access

published version

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Ševčík, Jan

;

Massaro, Maria Stefania

;

Pálek, Richard

;

Moulisová, Vladimíra

;

Liška, Václav

2024

,

Journal of Hepato-Biliary-Pancreatic Sciences

,

31

(11)

Reconstruction of extrahepatic bile ducts is a staple procedure of HPB surgery. The current standard for most cases is a nonanatomical bilioenteric reconstruction, a satisfactory option for the majority of patients. However, ...

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Association of long-term treatment outcomes with changes in PET/MRI characteristics and the type of early treatment response during concurrent radiochemotherapy in patients with locally advanced cervical cancer 

original article

open access

published version

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Vojtíšek, Radovan

;

Baxa, Jan

;

Hošek, Petr

;

Kovářová, Petra

;

Vítovec, Martin

;

Sukovská, Emília

;

Kosťun, Jan

;

Vlasák, Pavel

;

Presl, Jiří

;

Ferda, Jiří

;

Fínek, Jindřich

2025

,

Urban u. Vogel

,

Strahlentherapie und Onkologie

,

201

(5)

PURPOSE: We aimed to find predictive tumour characteristics as detected by interim positron-emission tomography/magnetic resonance imaging (PET/MRI) in cervical cancer patients. We also investigated the type of interim ...

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Non-viral HCC miRNA profiling reveals miR-1972 as a potential positive prognostic marker 

original article

open access

published version

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Mallela, Venkata Ramana

;

Rajtmajerová, Marie

;

Ali, Esraa

;

Červenková, Lenka

;

Trailin, Andriy

;

Hošek, Petr

;

Pálek, Richard

;

Daum, Ondřej

;

Liška, Václav

;

Hemminki, Kari Jussi

;

Ambrożkiewicz, Filip

2025

,

Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

,

Non-coding RNA Research

,

15

(December)

Background & Aims: Hepatocellular carcinoma (HCC) is the third deadliest cancer worldwide. Its high mortality is primarily attributed to late-stage diagnosis. While mutations in driver genes, such as those encoding β-catenin ...

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One-Step Nucleic Acid Amplification Analysis of Sentinel Lymphatic Nodes in Endometrial Cancer Patients (EU-OSNA): A European Multicenter Diagnostic Accuracy Study 

original article

open access

published version

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Kosťun, Jan

;

Nowosielski, Krzysztof

;

Jedryka, Marcin A

;

Hardisson, David

;

Restaino, Stefano

;

Gatius, Sonia

;

Novak, Zoltan

;

Lacalle, Amaia Sagasta

;

Lopez, Susana

;

Pešta, Martin

;

Zebalski, Marcin

;

Lepka, Piotr

;

Diestro, María Dolores

;

Vizzielli, Giuseppe

;

Matias-Guiu, Xavier

;

Echim, Tímea

;

Urkaray, Emma Natalia Camacho

;

Rienda, Iván

;

Slunečko, Robert

;

Czekanski, Andrzej

;

Berjón, Alberto

;

Mariuzzi, Laura

;

Velasco, Ana

;

Betenbuk, Judit

;

Merino, Isabel Guerra

;

Padilla-Iserte, Pablo

;

Stráník, Petr

;

Smoligová, Vendula

;

Presl, Jiří

2025

,

Blackwell Publishing

,

Cancer Medicine

,

14

(18)

OBJECTIVE: This European multicenter study aimed to assess the diagnostic accuracy of one-step nucleic acid amplification (OSNA) as the primary endpoint by comparing this method with ultrastaging for the detection of ...

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Targeted long-read sequencing identified a causal structural variant in X-linked nephrogenic diabetes insipidus 

original article

open access

published version

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Strych, Lukáš

;

Černá, Monika

;

Hejnalová, Markéta

;

Zavoral, Tomáš

;

Komrsková, Pavla

;

Tejcová, Jitka

;

Bitar, Ibrahim

;

Sládková, Eva

;

Sýkora, Josef

;

Šubrt, Ivan

2024

,

BMC Medical Genomics

,

17

(1)

Background: X-linked nephrogenic diabetes insipidus (NDI) is a rare genetic renal disease caused by pathogenic variants in the AVPR2 gene. Single nucleotide variants and small insertions/deletions in AVPR2 are reliably ...

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Multidrug-resistant ESBL-producing Klebsiella pneumoniae complex in Czech hospitals, wastewaters and surface waters 

original article

open access

accepted version

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Davidova-Gerzova, Lenka

;

Lausova, Jarmila

;

Sukkar, Iva

;

Nechutná, Lucie

;

Kubackova, Petra

;

Krůtová, Marcela

;

Bezdicek, Matej

;

Dolejská, Monika

2024

,

Antimicrobial Resistance and Infection Control

,

13

(1)

BACKGROUND: Multidrug-resistant (MDR) bacteria pose a significant challenge to the treatment of infectious diseases. Of particular concern are members of the Klebsiella pneumoniae species complex (KpSC), which are frequently ...

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A recurrent synonymous L1CAM variant in a fetus with hydrocephalus 

original article

open access

published version

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Šubrt, Ivan

;

Zavoral, Tomáš

;

Strych, Lukáš

;

Černá, Monika

;

Hejnalová, Markéta

;

Komrsková, Pavla

;

Tejcová, Jitka

2024

,

Human Genome Variation

,

11

(1)

We report the case of a hydrocephalic fetus in which clinical exome sequencing revealed a recurrent synonymous variant of unknown significance, c.453G>T, in the L1CAM gene. This report presents the second case of X-linked ...

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Research Output Typejournal article (39)abstract (2)... View MoreDate Issued2024 (19)2025 (10)2026 (7)2023 (4)2022 (1)Faculty / University unitFaculty of Medicine in Pilsen (41)
University Hospital in Pilsen (41)
University Hospital Hradec Králové (11)First Faculty of Medicine (9)Second Faculty of Medicine (7)... View MoreDepartment / Institute / ClinicBiomedical Center (28)Department of Oncology and Radiotherapy (11)Department of Microbiology (10)Department of Oncology and Radiotherapeutics (9)Department of Surgery (9)... View More

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