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The Prognostic Role of Baseline and Early Dynamics of Peripheral Blood Cell Ratios in Metastatic Renal Cell Carcinoma Patients Treated With Nivolumab

original article

open access

published version

Fiala, Ondřej

;

Tkadlecová, Michaela

;

Kopecký, Jindřich

;

Hošek, Petr

;

Studentova, Hana

;

Vočka, Michal

;

Matějů, Martin

;

Lohynská, Radka

;

Šiková, Dominika

;

Stránský, Petr

;

Kučera, Radek

;

Zemankova, Anezka

;

Spisarova, Martina

;

Priester, Peter

;

Kouril, Jan

;

Büchler, Tomáš

;

Grmelova, Lucie

;

Melichar, Bohuslav

;

Poprach, Alexandr

2026

,

Iōannīs G. Delīnasios

,

In Vivo

,

40

(2)

BACKGROUND/AIM: Immune checkpoint inhibitors (ICI), including nivolumab, have become the cornerstone of systemic treatment in metastatic renal cell carcinoma (mRCC). Blood-derived biomarkers including neutrophil-to-lymphocyte ...

Analysis of bacterial lipopolysaccharides ("serotyping") by MALDI-TOF mass spectometry: mission impossible?

abstract in conference proceedings

open access

published version

Ďaďovská, Lucia

;

Hrabák, Jaroslav

2023

,

Czech Chemical Society Symposium Series

,

21

In the last decade, the use of Matrix-Assisted Laser Desorption/Ionization Time Time-of-Flight mass spectrometry ( MALDI-TOF MS) revolutionary changed clinical microbiology. The technology allowed significant shortening ...

Expanding the Molecular-genetic Spectrum of Canalicular Adenoma-like Subtype of Pleomorphic Adenoma of Salivary Glands

original article

open access

published version

Klubíčková, Natálie

;

Loghides, Frederica

;

van den Hout, Mari F C M

;

Costes-Martineau, Valérie

;

Ferrara, Gerardo

;

Rito, Miguel

;

Hájková, Veronika

;

Grossmann, Petr

;

Šteiner, Petr

;

Kovářová, Inka

;

Michal, Michal

;

Leivo, Ilmo

;

Skálová, Alena

2025

,

Lippincott-Raven Publishers

,

The American Journal of Surgical Pathology

,

49

(6)

Canalicular tumors of the salivary glands have recently emerged as an entity characterized by distinct morphology and recurrent HMGA2 gene rearrangement. In this study, we analyzed 40 cases intending to elucidate their ...

Pooled analysis of 3,741 stool metagenomes from 18 cohorts for cross-stage and strain-level reproducible microbial biomarkers of colorectal cancer

original article

open access

published version

Piccinno, Gianmarco

;

Thompson, Kelsey N.

;

Manghi, Paolo

;

Ghazi, Andrew R.

;

Thomas, Andrew Maltez

;

Blanco-Miguez, Aitor

;

Asnicar, Francesco

;

Mladenovic, Katarina

;

Pinto, Federica

;

Armanini, Federica

;

Puncochar, Michal

;

Piperni, Elisa

;

Heidrich, Vitor

;

Fackelmann, Gloria

;

Ferrero, Giulio

;

Tarallo, Sonia

;

Nguyen, Long H.

;

Yan, Yan

;

Keles, Nazim A.

;

Tuna, Bilge G.

;

Vymetálková, Veronika

;

Trompetto, Mario

;

Liška, Václav

;

Hucl, Tomáš

;

Vodička, Pavel

;

Bencsikova, Beatrix

;

Carnogurska, Martina

;

Popovici, Vlad

;

Marmorino, Federica

;

Cremolini, Chiara

;

Pardini, Barbara

;

Cordero, Francesca

;

Song, Mingyang

;

Chan, Andrew T.

;

Derosa, Lisa

;

Zitvogel, Laurence

;

Huttenhower, Curtis

;

Naccarati, Alessio

;

Budinska, Eva

;

Segata, Nicola

2025

,

Nature Medicine

,

31

(7)

Associations between the gut microbiome and colorectal cancer (CRC) have been uncovered, but larger and more diverse studies are needed to assess their potential clinical use. We expanded upon 12 metagenomic datasets of ...

Percutaneous transthoracic needle biopsy of lung lesions is a safe method associated with a very low risk of pleural recurrence

original article

open access

published version

Svatoň, Martin

;

Havel, David

;

Burešová, Marcela

;

Baxa, Jan

;

Hošek, Petr

2025

,

Biomedical Papers

,

169

(1)

AIM: Percutaneous transthoracic needle biopsy (PTNB), an alternative to bronchoscopic confirmation of lung lesions, is today being associated with a risk of pneumothorax and hemorrhage. Further, there are no data on the ...

Prognostic Role of Prostate-specific Antigen Isoforms and Their Early Kinetics in Patients With Metastatic Castration-resistant Prostate Cancer Receiving New Generation Androgen Receptor Targeted Agents

original article

open access

published version

Fiala, Ondřej

;

Hošek, Petr

;

Korunková, Hana

;

Tkadlecová, Michaela

;

Hora, Milan

;

Šiková, Dominika

;

Stránský, Petr

;

Fínek, Jindřich

;

Kučera, Radek

;

Windrichová, Jindra

;

Topolčan, Ondřej

2025

,

Iōannīs G. Delīnasios

,

In Vivo

,

39

(2)

BACKGROUND/AIM: New generation androgen receptor-targeting agents (ARTA) have been in the spotlight for their efficacy in metastatic castration-resistant prostate cancer (mCRPC). Prostate-specific antigen (PSA) represents ...

Oral presentation of paraneoplastic pemphigus as the first sign of tonsillar HPV associated squamous cell carcinoma. A case report

casuistics

open access

published version

Liška, Jan

;

Lišková, Veronika

;

Trčka, Ondřej

;

Ondič, Ondrej

;

Hauer, Lukáš

;

Baxa, Jan

;

Kacerovská, Denisa

2022

,

Biomedical Papers

,

166

(4)

Background: Paraneoplastic pemphigus (PNP) in the oral cavity is a rare variant of blistering pemphigus disease closely associated with mostly malignant tumors. The diagnosis may even precede an underlying malignancy ...

Anatomical biliary reconstruction as an ultimum refugium for selective cases-History and current state of knowledge

summarizing article

open access

published version

Ševčík, Jan

;

Massaro, Maria Stefania

;

Pálek, Richard

;

Moulisová, Vladimíra

;

Liška, Václav

2024

,

Journal of Hepato-Biliary-Pancreatic Sciences

,

31

(11)

Reconstruction of extrahepatic bile ducts is a staple procedure of HPB surgery. The current standard for most cases is a nonanatomical bilioenteric reconstruction, a satisfactory option for the majority of patients. However, ...

Association of long-term treatment outcomes with changes in PET/MRI characteristics and the type of early treatment response during concurrent radiochemotherapy in patients with locally advanced cervical cancer

original article

open access

published version

Vojtíšek, Radovan

;

Baxa, Jan

;

Hošek, Petr

;

Kovářová, Petra

;

Vítovec, Martin

;

Sukovská, Emília

;

Kosťun, Jan

;

Vlasák, Pavel

;

Presl, Jiří

;

Ferda, Jiří

;

Fínek, Jindřich

2025

,

Urban u. Vogel

,

Strahlentherapie und Onkologie

,

201

(5)

PURPOSE: We aimed to find predictive tumour characteristics as detected by interim positron-emission tomography/magnetic resonance imaging (PET/MRI) in cervical cancer patients. We also investigated the type of interim ...

Non-viral HCC miRNA profiling reveals miR-1972 as a potential positive prognostic marker

original article

open access

published version

Mallela, Venkata Ramana

;

Rajtmajerová, Marie

;

Ali, Esraa

;

Červenková, Lenka

;

Trailin, Andriy

;

Hošek, Petr

;

Pálek, Richard

;

Daum, Ondřej

;

Liška, Václav

;

Hemminki, Kari Jussi

;

Ambrożkiewicz, Filip

2025

,

Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

,

Non-coding RNA Research

,

15

(December)

Background & Aims: Hepatocellular carcinoma (HCC) is the third deadliest cancer worldwide. Its high mortality is primarily attributed to late-stage diagnosis. While mutations in driver genes, such as those encoding β-catenin ...

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