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One-Step Nucleic Acid Amplification Analysis of Sentinel Lymphatic Nodes in Endometrial Cancer Patients (EU-OSNA): A European Multicenter Diagnostic Accuracy Study

original article

open access

published version

Kosťun, Jan

;

Nowosielski, Krzysztof

;

Jedryka, Marcin A

;

Hardisson, David

;

Restaino, Stefano

;

Gatius, Sonia

;

Novak, Zoltan

;

Lacalle, Amaia Sagasta

;

Lopez, Susana

;

Pešta, Martin

;

Zebalski, Marcin

;

Lepka, Piotr

;

Diestro, María Dolores

;

Vizzielli, Giuseppe

;

Matias-Guiu, Xavier

;

Echim, Tímea

;

Urkaray, Emma Natalia Camacho

;

Rienda, Iván

;

Slunečko, Robert

;

Czekanski, Andrzej

;

Berjón, Alberto

;

Mariuzzi, Laura

;

Velasco, Ana

;

Betenbuk, Judit

;

Merino, Isabel Guerra

;

Padilla-Iserte, Pablo

;

Stráník, Petr

;

Smoligová, Vendula

;

Presl, Jiří

2025

,

Blackwell Publishing

,

Cancer Medicine

,

14

(18)

OBJECTIVE: This European multicenter study aimed to assess the diagnostic accuracy of one-step nucleic acid amplification (OSNA) as the primary endpoint by comparing this method with ultrastaging for the detection of ...

Targeted long-read sequencing identified a causal structural variant in X-linked nephrogenic diabetes insipidus

original article

open access

published version

Strych, Lukáš

;

Černá, Monika

;

Hejnalová, Markéta

;

Zavoral, Tomáš

;

Komrsková, Pavla

;

Tejcová, Jitka

;

Bitar, Ibrahim

;

Sládková, Eva

;

Sýkora, Josef

;

Šubrt, Ivan

2024

,

BMC Medical Genomics

,

17

(1)

Background: X-linked nephrogenic diabetes insipidus (NDI) is a rare genetic renal disease caused by pathogenic variants in the AVPR2 gene. Single nucleotide variants and small insertions/deletions in AVPR2 are reliably ...

Multidrug-resistant ESBL-producing Klebsiella pneumoniae complex in Czech hospitals, wastewaters and surface waters

original article

open access

accepted version

Davidova-Gerzova, Lenka

;

Lausova, Jarmila

;

Sukkar, Iva

;

Nechutná, Lucie

;

Kubackova, Petra

;

Krůtová, Marcela

;

Bezdicek, Matej

;

Dolejská, Monika

2024

,

Antimicrobial Resistance and Infection Control

,

13

(1)

BACKGROUND: Multidrug-resistant (MDR) bacteria pose a significant challenge to the treatment of infectious diseases. Of particular concern are members of the Klebsiella pneumoniae species complex (KpSC), which are frequently ...

A recurrent synonymous L1CAM variant in a fetus with hydrocephalus

original article

open access

published version

Šubrt, Ivan

;

Zavoral, Tomáš

;

Strych, Lukáš

;

Černá, Monika

;

Hejnalová, Markéta

;

Komrsková, Pavla

;

Tejcová, Jitka

2024

,

Human Genome Variation

,

11

(1)

We report the case of a hydrocephalic fetus in which clinical exome sequencing revealed a recurrent synonymous variant of unknown significance, c.453G>T, in the L1CAM gene. This report presents the second case of X-linked ...

Nonprocedural bleeding after left atrial appendage closure versus direct oral anticoagulants: A subanalysis of the randomized PRAGUE-17 trial

original article

open access

published version

Branny, Marian

;

Osmančík, Pavel

;

Kala, Petr

;

Poloczek, Martin

;

Heřman, Dalibor

;

Neužil, Petr

;

Hála, Pavel

;

Táborský, Miloš

;

Šťásek, Josef

;

Haman, Luděk

;

Chovančík, Jan

;

Červinka, Pavel

;

Holý, Jiří

;

Kovárník, Tomáš

;

Zemánek, David

;

Havránek, Štěpán

;

Vančura, Vlastimil

;

Peichl, Petr

;

Toušek, Petr

;

Hozman, Marek

;

Lekešová, Veronika

;

Jarkovský, Jiří

;

Nováčková, Martina

;

Benešová, Klára

;

Widimský, Petr

;

Reddy, Vivek Y

2023

,

Journal of Cardiovascular Electrophysiology

,

34

(9)

INTRODUCTION: Observational studies have shown low bleeding rates in patients with atrial fibrillation (AF) treated by left atrial appendage closure (LAAC); however, data from randomized studies are lacking. This study ...

Outcomes Of Patients With Myocardial Infarction And Cardiogenic Shock Treated With Culprit Vessel-Only Versus Multivessel Primary PCI

original article

open access

published version

Hlinomaz, Ota

;

Moťovská, Zuzana

;

Kala, Petr

;

Hromádka, Milan

;

Přeček, Jan

;

Mrózek, Jan

;

Červinka, Pavel

;

Kettner, Jiří

;

Matějka, Jan

;

Zohoor, Ahmad

;

Bis, Josef

;

Jarkovský, Jiří

2024

,

Hellenic Journal of Cardiology

,

76

(MAR-APR)

INTRODUCTION AND OBJECTIVES: Multivessel primary percutaneous coronary intervention (pPCI) is still often used in patients with ST-elevation myocardial infarction (STEMI) and cardiogenic shock (CS). The study aimed to ...

The Czech National MS Registry (ReMuS): Data trends in multiple sclerosis patients whose first disease-modifying therapies were initiated from 2013 to 2021

original article

open access

published version

Šťastná, Dominika

;

Drahota, Jiří

;

Lauer, Michal

;

Mazouchová, Aneta

;

Meňkyová, Ingrid

;

Adámková, Jana

;

Ampapa, Radek

;

Dufek, Michal

;

Grunermelova, Marketa

;

Hradilek, Pavel

;

Kubala Havrdová, Eva

;

Mareš, Jan

;

Martínková, Alena

;

Pavelek, Zbyšek

;

Peterka, Marek

;

Recmanová, Eva

;

Ročková, Petra

;

Štětkářová, Ivana

;

Štourač, Pavel

;

Vachová, Marta

;

Horáková, Dana

2024

,

Palacký University

,

Biomedical Papers

,

168

(3)

AIMS: Multiple sclerosis treatment strategies are changing in the Czech Republic. According to data from 2013-2021, the proportion of patients starting high-efficacy disease-modifying therapies is increasing. In this survey, ...

Pembrolizumab versus Pembrolizumab plus Chemotherapy in Non-small Cell Lung Cancer with High PD-L1 Expression - Multicenter Real-world Evidence Study

original article

open access

published version

Svatoň, Martin

;

Knetki-Wroblewska, Magdalena

;

Hošek, Petr

;

Chowaniecova, Gabriela

;

Špaček, Jan

;

Fischer, Ondřej

;

Bílek, Ondřej

;

Hrnčiarik, Michal

;

Kauffmann-Guerrero, Diego

2025

,

Ivyspring International Publisher

,

Journal of Cancer

,

16

(10)

Background: Patients with non-small cell lung cancer (NSCLC) with PD-Ll expression ~ 50% can be treated with immunotherapy alone or with a combination of immunotherapy and chemotherapy. One of these options is treatment ...

Utilization of healthcare services in acute myocardial infarction and the risk of out-of-hospital cardiac death

letter to the editors

open access

published version

Moťovská, Zuzana

;

Hlinomaz, Ota

;

Hromádka, Milan

;

Mrózek, Jan

;

Přeček, Jan

;

Kala, Petr

;

Muzafarova, Tamilla

;

Kettner, Jiří

;

Matějka, Jan

;

Bis, Josef

;

Červinka, Pavel

;

Tomašov, Pavol

;

Klechová, Anna

;

Šanca, Ondřej

;

Jarkovský, Jiří

2024

,

Panminerva Medica

,

66

(1)

COVID-19 represented a significant challenge to cardiovascular (cV) medicine research, treatment, prevention, and, to a considerable extent, case management. The global pandemic viral infection increased the risk of ...

Monitoring the Alternative Pathway of Meropenem Degradation by OXA-48-Type Carbapenemases

abstract in conference proceedings

open access

published version

Študentová, Vendula

;

Pašková, Veronika

;

Ďaďovská, Lucia

;

Hrabák, Jaroslav

2025

,

Praha

,

Česká společnost chemická

,

Czech Chemical Society Symposium Series

,

23

(4)

Background:Overuse of carbapenems has been associated with an increasing prevalence of resistance, particularly among the Enterobacterales, Pseudomonasspp., and Acinetobacter spp. Resistance is mediated by the ...

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