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Correlation of p53 oligomeric status and its subcellular localization in the presence of the AML-associated NPM mutant

original article

open access

published version

Holoubek, Aleš

;

Strachotová, Dita

;

Wolfová, Kateřina

;

Otevřelová, Petra

;

Belejová, Sára

;

Röselová, Pavla

;

Benda, Aleš

;

Brodská, Barbora

;

Heřman, Petr

2025

,

Public Library of Science

,

PLoS One

,

20

(5)

Tumor suppressor p53 is a key player in the cell response to DNA damage that suffers by frequent inactivating aberrations. Some of them disturb p53 oligomerization and influence cell decision between proliferation, growth ...

C–H amination reactions inside α-cyclodextrin supramolecular capsule

original article

open access

published version

Barvík, Ivan

;

Císařová, Ivana

;

Dian, Juraj

;

Holovko-Kamoshenkova, Oksana M.

;

Štícha, Martin

;

Tošner, Zdeněk

;

Jindřich, Jindřich

;

Hrdina, Radim

2025

,

Royal Society of Chemistry

,

Organic and Biomolecular Chemistry

,

23

(47)

We describe the photochemical generation of an alkoxycarbonylnitrene species in a supramolecular capsule and its reactivity. 2-Adamantyl-carbonazidate was co-crystallized in a supramolecular capsule consisting of two ...

Drone-based vertical profiling of particulate matter size distribution and carbonaceous aerosols: urban vs. rural environment

original article

open access

published version

Julaha, Kajal

;

Ždímal, Vladimír

;

Mbengue, Saliou

;

Brus, David

;

Zíková, Naděžda

2025

,

Copernicus Publ.

,

Atmospheric Chemistry and Physics

,

25

(23)

The study presents drone-based measurements to investigate the seasonal vertical variability of equivalent black carbon (eBC) mass and particle number concentrations (PNC) at a rural and urban site in the Czech Republic. ...

The minimal membrane requirements for BAX-induced pore opening upon exposure to oxidative stress

original article

open access

published version

Mystek, Paweł

;

Singh, Vandana

;

Horváth, Matěj

;

Honzejková, Karolína

;

Riegerová, Petra

;

Evci, Hüseyin

;

Hof, Martin

;

Obšil, Tomáš

;

Šachl, Radek

2024

,

Biophysical Journal

,

123

(20)

Perforation of the outer mitochondrial membrane triggered by BAX and facilitated by its main activator cBID is a fundamental process in cell apoptosis. Here, we employ a newly designed correlative approach based on a ...

Vaccinia virus mRNAs containing long 5'-poly(A)-leaders lack a canonical 5'-methylguanosine cap

original article

open access

published version

Vopálenský, Václav

;

Sýkora, Michal

;

Mělková, Zora

;

Barvík, Ivan

;

Horáčková, Kamila

;

Mašek, Tomáš

;

Pospíšek, Martin

2025

,

Nature Publishing Group

,

Nature Communications

,

16

(1)

The vaccinia virus (VACV) is a prototypical poxvirus that was originally used to eradicate smallpox. Half a century ago, investigation into VACV mRNA substantially contributed to the fundamental discovery of the 5' mRNA ...

LOMS.cz computational platform for high-throughput classical and combinatorial Judd-Ofelt analysis and rare-earth spectroscopy

original article

open access

published version

Hrabovský, Jan

;

Vařák, Petr

;

Kryštůfek, Robin

2025

,

Springer Nature

,

Scientific Reports

,

15

(1)

We present LOMS.cz (Luminescence, Optical and Magneto-optical Software), an open-source computational platform that addresses the long-standing challenge of standardizing Judd-Ofelt (JO) calculations in rare-earth spectroscopy. ...

Classical and combinatorial Judd–Ofelt analysis of spectroscopic properties in Er-doped materials: TeO₂–ZnO–BaO:Er⁽³⁺⁾ glasses

original article

open access

published version

Hrabovský, Jan

;

Vařák, Petr

;

Oswald, Jiří

;

Kryštůfek, Robin

;

Dědič, Václav

;

Šlang, Stanislav

;

Beneš, Ludvík

;

Wágner, Tomáš

;

Střižík, Lukáš

2025

,

IOP Publishing Ltd

,

JPhys Photonics

,

7

(2)

A systematic study of the doping ability of the TeO2-ZnO-BaO glassy system with Er(3+) ions is presented to achieve strong Stokes/upconversion photoluminescence (UPL) emission and to determine the optimal experimental ...