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The evaluation of an automated mariPOC SARS-CoV-2 antigen test compared to RT-qPCR SARS-CoV-2 assay and comparison of its sensitivity in Delta- and Omicron-variant samples
(2022)
Background The rapid diagnostics tests for SARS-CoV-2 antigen vary in their sensitivities, and moreover, genomic mutations may further affect the performance of the assays. We aimed to evaluate the analytical performance ...
COVID-19 Vaccination among Czech Dentists
(2022)
This work describes and evaluates vaccination against COVID-19 among members of the Czech Dental Chamber during the pre-booster vaccination phase. A cross-sectional online survey was conducted between 23 June and 4 September ...
Specific Immune Response Against SARS-CoV-2
(2023)
The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide. For effective treatment and introduction of appropriate antipandemic measures, it is necessary to understand the development ...
Vývoj metodiky pro analýzu T-buněčné odpovědi proti viru SARS-CoV-2
Development of a procedure for the analysis of the T-cell response against SARS-CoV-2 virus
V roce 2020 způsobil koronavirus SARS-CoV-2 pandemii onemocnění covid-19. Pro detekci buněčné odpovědi vyvolané infekcí tímto virem byl vyvinut vysoce citlivý test ELISPOT detekující specifické lymfocyty T produkující ...
Can variants, reinfection, symptoms and test types affect COVID-19 diagnostic performance? A large-scale retrospective study of AG-RDTs during circulation of Delta and Omicron variants, Czechia, December 2021 to February 2022
(2023)
BackgroundThe sensitivity and specificity of selected antigen detection rapid diagnostic tests (AG-RDTs) for SARS-CoV-2 were determined in the unvaccinated population when the Delta variant was circulating. Viral loads, ...
Characterization of the evolutionary and virological aspects of mutations in the receptor binding motif of the SARS-CoV-2 spike protein
(2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has substantially diversified during the pandemic, resulting in the successive emergence of variants characterized by various mutations. It has been observed ...
Specific Immunity to SARS-CoV-2 Infection
(Česká zemědělská univerzita, Praha, 2024)
The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide.For effective treatment and introduction of appropriate anti-pandemic measures, it is necessary tounderstand the development ...