Loss of ADAR1 protein induces changes in small RNA landscape in hepatocytes

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Autor
Roučová, KristinaORCiD Profile - 0000-0001-8081-4538WoS Profile - P-9197-2017
Vopálenský, VáclavORCiD Profile - 0000-0002-4858-4645WoS Profile - Q-6418-2017Scopus Profile - 8575785500
Mašek, TomášORCiD Profile - 0000-0001-8732-0565WoS Profile - Q-4636-2017Scopus Profile - 6603131017
Provazník, Jan
Landry, Jonathan
Azevedo, Nayara
Ehler, EdvardORCiD Profile - 0000-0003-1774-0091
Beneš, Vladimír
Pospíšek, MartinORCiD Profile - 0000-0002-9490-8911WoS Profile - A-9100-2008Scopus Profile - 6602708932
RNA Society

Datum vydání
2023
Publikováno v
The 28th Annual Meeting of the RNA Society
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Abstrakt
In recent years, numerous evidence has been accumulated about the extent of A-to-I editing in human RNAs and the key role ADAR1 plays in the cellular editing machinery and cellular antiviral response. It has been shown that A-to-I editing occurrence and frequency are tissue specific and essential for some tissue development, such as liver.
Klíčová slova
ADAR1, RNA, hepatocytes, protein
Trvalý odkaz
https://hdl.handle.net/20.500.14178/2005
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