Přírodovědecká fakulta
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Poslední příspěvky
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The development of L. major, L. donovani and L. martiniquensis, Leishmania currently emerging in Europe, in the sand fly species Phlebotomus perniciosus and P. tobbi
původní článek
open access
vydavatelská verze
2024
,PLoS Neglected Tropical Diseases
,18
(10)
Background: Several new species of Leishmania have recently emerged in Europe, probably as the result of global changes and increased human migration from endemic areas. In this study, we tested whether two sand fly species, ...
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Microplastics originated from agricultural mulching films affect enchytraeid multigeneration reproduction and soil properties
původní článek
open access
vydavatelská verze
2024
,Journal of Hazardous Materials
,479
(November)
Microplastics (MPs) are increasingly entering agricultural soils, often from the breakdown of agricultural plastics (e.g., mulching films). This study investigates the effects of realistic MPs from different mulching films: ...
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Spatial immune heterogeneity in a mouse tumor model after immunotherapy
původní článek
open access
vydavatelská verze
2025
,Cancer Science
,116
(3)
Cancer immunotherapy is increasingly used in clinical practice, but its success rate is reduced by tumor escape from the immune system. This may be due to the genetic instability of tumor cells, which allows them to adapt ...
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Exploring vulnerability amplification in regional health inequality: COVID-19 case study in Czechia
původní článek
open access
vydavatelská verze
2025
,Applied Geography
,177
(April 2025)
This paper proposes a novel conceptual framework of vulnerability amplification to examine regional health inequalities. It combines differential vulnerability in health and social amplification of risk, as mechanisms of ...
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Azadirachtin disrupts ecdysone signaling and alters sand fly immunity
původní článek
open access
vydavatelská verze
2024
,Parasites & Vectors
,17
(1)
BackgroundLeishmaniasis is a group of neglected vector-borne diseases transmitted by phlebotomine sand flies. Leishmania parasites must overcome various defenses in the sand fly midgut, including the insects's immune ...
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Auer rod-positive acute leukemia with predominantly lymphoid immunophenotype: Report on 11 cases and review of literature
původní článek
open access
vydavatelská verze
2025
,Pediatric Blood and Cancer
,72
(1)
BACKGROUND: Auer rods (AuRs) are prominent intracellular structures found almost exclusively in myeloid cell malignancies, such as acute myeloid leukemia (AML), chronic and juvenile myelomonocytic leukemia and myelodysplastic ...
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Different amyloid β42 preparations induce different cell death pathways in the model of SH-SY5Y neuroblastoma cells
původní článek
open access
vydavatelská verze
2024
,Cellular & Molecular Biology Letters
,29
(1)
Amyloid beta 42 (A beta 42) plays a decisive role in the pathology of Alzheimer's disease. The A beta 42 peptide can aggregate into various supramolecular structures, with oligomers being the most toxic form. However, ...
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Guanine Crystal Formation and Behavior in Light Adaptation and Deuteration of the Dinoflagellate Amphidinium carterae
poster
omezený přístup
postprint
2024
Biogenic guanine crystals are crucial for light perception in animals and photosynthetic microalgae. Their high refractive index and plate-like arrangement allow these crystals to participate in scattering, reflection, and ...
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The minimal membrane requirements for BAX-induced pore opening upon exposure to oxidative stress
původní článek
open access
vydavatelská verze
2024
,Biophysical Journal
,123
(20)
Perforation of the outer mitochondrial membrane triggered by BAX and facilitated by its main activator cBID is a fundamental process in cell apoptosis. Here, we employ a newly designed correlative approach based on a ...
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Metal(loid)s and their bioaccessibility in urban soils from residential areas of a medieval mining town
původní článek
open access
vydavatelská verze
2025
,Environmental Geochemistry and Health
,47
(3)
In historic mining towns, where mining activities were abandoned many decades or even centuries ago, legacy contaminations can be remobilized and redispersed, representing a threat for the environment and human health. ...
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High Inter-Specific Diversity and Seasonality of Trunk Radial Growth in Trees Along an Afrotropical Elevational Gradient
původní článek
open access
vydavatelská verze
2024
,Plant, Cell & Environment
,48
(3)
Understanding mechanisms driving tropical tree growth is essential for comprehending carbon sequestration and predicting the future of tropical forests amid rapid deforestation. We conducted a natural experiment in Mount ...
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Between- versus within-species variation in plant-soil feedback relates to different functional traits, but exudate variability is involved at both scales
původní článek
open access
vydavatelská verze
2024
,Functional Ecology
,38
(5)
Plant-soil feedback-feedback from plant-induced changes in soil properties to plant fitness-is increasingly shown to drive the maintenance of local plant diversity at both interspecific and intraspecific levels. A robust ...
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Small-molecule activators of NRF1 transcriptional activity prevent protein aggregation
původní článek
open access
vydavatelská verze
2025
,Biomedicine & Pharmacotherapy
,183
(February)
Intracellular protein aggregation causes proteotoxic stress, underlying highly debilitating neurodegenerative disorders in parallel with decreased proteasome activity. Nevertheless, under such stress conditions, the ...
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Jag1 insufficiency alters liver fibrosis via T cell and hepatocyte differentiation defects
původní článek
open access
vydavatelská verze
2024
,EMBO Molecular Medicine
,16
(11)
Fibrosis contributes to tissue repair, but excessive fibrosis disrupts organ function. Alagille syndrome (ALGS, caused by mutations in JAGGED1) results in liver disease and characteristic fibrosis. Here, we show that ...
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The effects of temperature on plasticity, shape symmetry and seasonal variation in the freshwater benthic green microalga Micrasterias thomasiana
původní článek
open access
vydavatelská verze
2024
,Aquatic Ecology
,58
(3)
Desmids are usually abundant in shallow peatland pools. In these localities, water temperature is closely linked to seasonal fluctuations in air temperature, so with increasing temperature extremes in temperate ecosystems, ...
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Non-Native, Non-Naturalised Plants Suffer Less Herbivory Than Native Plants Across European Botanical Gardens
původní článek
open access
vydavatelská verze
2024
,Diversity and Distributions
,30
(12)
AIM: The enemy release hypothesis states that the invasion success of non-native species is partly due to their escape from natural enemies, e.g., herbivores. Large-scale studies of herbivory using multiple species across ...
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Attributing the effects of climate change and forest disturbance on runoff using distributed modeling and indicators of hydrological alteration in Central European montane basins
původní článek
open access
vydavatelská verze
2025
,Journal of Hydrology: Regional Studies
,57
(Neuvedeno)
This study examines the impacts of climate warming and forest disturbances on hydrological alterations in montane headwater basins. Using the MIKE SHE distributed hydrological model, scenario-based simulations assessed ...
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Income Fluctuations and Subjective Well-being: The Mediating Effects of Occupational Switching and Remittances
původní článek
open access
vydavatelská verze
2024
,Journal of Happiness Studies
,25
(8)
Does money bring happiness? To answer this question, I study the consequences of income fluctuations caused by commodity price changes on well-being patterns in regions specializing in export agriculture. Using nationally ...
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Persistence Over Millennia Through Extreme Clonal Longevity: Phylogenomic Insight Into History of One of the World's Rarest Plant Species
původní článek
open access
vydavatelská verze
2025
,Journal of Biogeography
,52
(1)
Aim: The evolutionary history of European alpine plant species with medium to large geographical ranges is relatively well explored. Here, we investigate the genetic structure and diversity of an extremely narrow endemic ...
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Socioeconomic and health predictors for food insecurity, and implications for dietary inequality during the COVID-19 pandemic in Czechia
abstrakt v konferenčním sborníku
open access
vydavatelská verze
2024
,Basel
,S. Karger
,Obesity Facts
,17
(Suppl. 1)
Food insecurity is a profound public health concern. It is affected by social determinants of health and leads to malnutrition and hence poor health. COVID-19 impacted people disproportionately and exacerbated preexisting ...
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