Now showing items 1-20 of 1069

    • Isokalorická KETOgenní dieta ZLEPŠUJE insulinovou senzitivitu U OBÉZNÍCH ŽEN 

      poster

      open access

      published version

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      Šebo, Viktor

      ;

      Koudelková, Kateřina

      ;

      Krauzová, Eva

      ;

      Wilhelm, Marek

      ;

      Heniková, Marina

      ;

      Gojda, Jan

      ;

      Rossmeislová, Lenka

      ;

      Šiklová, Michaela

      2023

    • Virological characteristics of the SARS-CoV-2 BA.2.86 variant 

      original article

      open access

      published version

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      Tamura, Tomokazu

      ;

      Mizuma, Keita

      ;

      Nasser, Hesham

      ;

      Deguchi, Sayaka

      ;

      Padilla-Blanco, Miguel

      ;

      Oda, Yoshitaka

      ;

      Uriu, Keiya

      ;

      Tolentino, Jarel E. M.

      ;

      Tsujino, Shuhei

      ;

      Suzuki, Rigel

      ;

      Kojima, Isshu

      ;

      Nao, Naganori

      ;

      Shimizu, Ryo

      ;

      Wang, Lei

      ;

      Tsuda, Masumi

      ;

      Jonathan, Michael

      ;

      Kosugi, Yusuke

      ;

      Guo, Ziyi

      ;

      Hinay, Alfredo A.

      ;

      Putri, Olivia

      ;

      Kim, Yoonjin

      ;

      Tanaka, Yuri L.

      ;

      Asakura, Hiroyuki

      ;

      Nagashima, Mami

      ;

      Sadamasu, Kenji

      ;

      Yoshimura, Kazuhisa

      ;

      Saito, Akatsuki

      ;

      Ito, Jumpei

      ;

      Irie, Takashi

      ;

      Tanaka, Shinya

      ;

      Zahradník, Jiří

      ;

      Ikeda, Terumasa

      ;

      Takayama, Kazuo

      ;

      Matsuno, Keita

      ;

      Fukuhara, Takasuke

      ;

      Sato, Kei

      2024

      ,

      Cell Host and Microbe

      ,

      32

      (2)

      In late 2023, several SARS-CoV-2 XBB descendants, notably EG.5.1, were predominant worldwide. However, a distinct SARS-CoV-2 lineage, the BA.2.86 variant, also emerged. BA.2.86 is phylogenetically distinct from other Omicron ...

    • Is speech function lateralised in the basal ganglia? Evidence from de novo Parkinson's disease 

      original article

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      Rusz, Jan

      ;

      Dušek, Petr

      ;

      Tykalova, Tereza

      ;

      Novotny, Michal

      ;

      Illner, Vojtech

      ;

      Simek, Michal

      ;

      Kouba, Tomas

      ;

      Kryze, Petr

      ;

      Zogala, David

      ;

      Růžička, Evžen

      ;

      Sousa, Mario

      ;

      Jorge, Adriana

      ;

      Nef, Tobias

      ;

      Krack, Paul

      2024

      ,

      Journal of Neurology, Neurosurgery and Psychiatry

      ,

      AHEAD OF PRINT

      (Published Online First: 17 September)

      Background: Research on the possible influence of lateralised basal ganglia dysfunction on speech in Parkinson's disease is scarce. This study aimed to compare speech in de-novo, drug-naive patients with Parkinson's disease ...

    • Lipid measures are associated with cognitive functioning in multiple sclerosis patients 

      original article

      open access

      published version

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      Lőrincz, Balázs

      ;

      Motýl, Jiří

      ;

      Friedová, Lucie

      ;

      Hrych, Daniel

      ;

      Kubala Havrdová, Eva

      ;

      Krásenský, Jan

      ;

      Urban, Tadeáš

      ;

      Kober, Tobias

      ;

      Marechal, Benedicte

      ;

      Vaněčková, Manuela

      ;

      Horáková, Dana

      ;

      Vrablík, Michal

      ;

      Uher, Tomáš

      2024

      ,

      Multiple Sclerosis and Related Disorders

      ,

      91

      (November)

      Background: An association between lipid measures and cognitive decline in patients with multiple sclerosis (MS) has been suggested. Objectives: This study aimed to investigate relationships between lipid profile and ...

    • Iron chelators as mitophagy agents: Potential and limitations 

      summarizing article

      open access

      published version

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      Brogyányi, Tereza

      ;

      Kejík, Zdeněk

      ;

      Veselá, Kateřina

      ;

      Dytrych, Petr

      ;

      Hoskovec, David

      ;

      Masařík, Michal

      ;

      Babula, Petr

      ;

      Kaplánek, Robert

      ;

      Přibyl, Tomáš

      ;

      Zelenka, Jaroslav

      ;

      Ruml, Tomáš

      ;

      Vokurka, Martin

      ;

      Martásek, Pavel

      ;

      Jakubek, Milan

      2024

      ,

      Biomedicine & Pharmacotherapy

      ,

      179

      (October)

      Mitochondrial autophagy (mitophagy) is very important process for the maintenance of cellular homeostasis, functionality and survival. Its dysregulation is associated with high risk and progression numerous serious diseases ...

    • Preoperative cognitive profile predictive of cognitive decline after subthalamic deep brain stimulation in Parkinson's disease 

      original article

      open access

      published version

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      Mana, Josef

      ;

      Bezdíček, Ondřej

      ;

      Růžička, Filip

      ;

      Lasica, Andrej

      ;

      Šmídová, Anna

      ;

      Klempířová, Olga

      ;

      Nikolai, Tomáš

      ;

      Uhrová, Tereza

      ;

      Růžička, Evžen

      ;

      Urgošík, Dušan

      ;

      Jech, Robert

      2024

      ,

      European Journal of Neuroscience

      ,

      60

      (7)

      Cognitive decline represents a severe non-motor symptom of Parkinson's disease (PD) that can significantly reduce the benefits of subthalamic deep brain stimulation (STN DBS). Here, we aimed to describe post-surgery cognitive ...

    • Simple 3D spheroid cell culture model for studies of prion infection 

      original article

      open access

      published version

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      Fremuntová, Zuzana

      ;

      Bačkovská Hanusová, Zdeňka

      ;

      Soukup, Jakub

      ;

      Moško, Tibor

      ;

      Matěj, Radoslav

      ;

      Holada, Karel

      2024

      ,

      European Journal of Neuroscience

      ,

      60

      (4)

      Mouse neuronal CAD 5 cell line effectively propagates various strains of prions. Previously, we have shown that it can also be differentiated into the cells morphologically resembling neurons. Here, we demonstrate that CAD ...

    • Many Labs 5: Testing Pre-Data-Collection Peer Review as an Intervention to Increase Replicability 

      original article

      open access

      published version

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      Ebersole, Charles

      ;

      Mathur, Maya B.

      ;

      Baranski, Erica

      ;

      Bart-Plange, Diane-Jo

      ;

      Ropovik, Ivan

      2021

      ,

      Advances in Methods and Practices in Psychological Science

      ,

      3

      (3)

      Replication studies in psychological science sometimes fail to reproduce prior findings. If these studies use methods that are unfaithful to the original study or ineffective in eliciting the phenomenon of interest, then ...

    • Rapid method for screening of both calcium and magnesium chelation with comparison of 21 known metal chelators 

      original article

      open access

      published version

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      Konečný, Lukáš

      ;

      Lomozová, Zuzana

      ;

      Karabanovich, Galina

      ;

      Roh, Jaroslav

      ;

      Vávrová, Kateřina

      ;

      Mladěnka, Přemysl

      2024

      ,

      Journal of Biological Inorganic Chemistry

      ,

      XXX

      (October)

      The aim of this study was to develop an affordable, rapid but sensitive and precise method for determining the degree of chelation of calcium and magnesium ions. Spectrophotometric method using o-cresolphthalein complexone ...

    • Different behavior of food-related benzoic acids toward iron and copper 

      original article

      open access

      published version

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      Harčárová, Patrícia

      ;

      Lomozová, Zuzana

      ;

      Kallivretaki, Maria

      ;

      Karlíčková, Jana

      ;

      Kučera, Radim

      ;

      Mladěnka, Přemysl

      2025

      ,

      Food Chemistry

      ,

      462

      (January)

      Benzoic acids are commonly found in food and are also produced by human microbiota from other dietary phenolics. The aim was to investigate the interactions of 8 food-related benzoic acids with the physiological metals ...

    • Polymorphisms in transcription factor binding sites and enhancer regions and pancreatic ductal adenocarcinoma risk 

      original article

      open access

      published version

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      Ünal, Pelin

      ;

      Lu, Ye

      ;

      Bueno-de-Mesquita, Bas

      ;

      van Eijck, Casper H. J.

      ;

      Talar-Wojnarowska, Renata

      ;

      Szentesi, Andrea

      ;

      Gazouli, Maria

      ;

      Kreivenaite, Edita

      ;

      Tavano, Francesca

      ;

      Małecka-Wojciesko, Ewa

      ;

      Erőss, Bálint

      ;

      Oliverius, Martin

      ;

      Bunduc, Stefania

      ;

      Nóbrega Aoki, Mateus

      ;

      Vodičková, Ludmila

      ;

      Boggi, Ugo

      ;

      Giaccherini, Matteo

      ;

      Kondrackiene, Jurate

      ;

      Chammas, Roger

      ;

      Palmieri, Orazio

      ;

      Theodoropoulos, George E.

      ;

      Bijlsma, Maarten F.

      ;

      Basso, Daniela

      ;

      Mohelníková-Duchoňová, Beatrice

      ;

      Souček, Pavel

      ;

      Izbicki, Jakob R

      ;

      Kiudelis, Vytautas

      ;

      Vanella, Giuseppe

      ;

      Arcidiacono, Paolo Giorgio

      ;

      Włodarczyk, Barbara

      ;

      Hackert, Thilo

      ;

      Schöttker, Ben

      ;

      Uzunoglu, Faik G.

      ;

      Bambi, Franco

      ;

      Goetz, Mara

      ;

      Hlaváč, Viktor

      ;

      Brenner, Hermann

      ;

      Perri, Francesco

      ;

      Carrara, Silvia

      ;

      Landi, Stefano

      ;

      Hegyi, Péter

      ;

      Dijk, Frederike

      ;

      Maiello, Evaristo

      ;

      Capretti, Giovanni

      ;

      Testoni, Sabrina Gloria Giulia

      ;

      Petrone, Maria Chiara

      ;

      Stocker, Hannah

      ;

      Ermini, Stefano

      ;

      Archibugi, Livia

      ;

      Gentiluomo, Manuel

      ;

      Cavestro, Giulia Martina

      ;

      Pezzilli, Raffaele

      ;

      Di Franco, Gregorio

      ;

      Milanetto, Anna Caterina

      ;

      Sperti, Cosimo

      ;

      Neoptolemos, John P.

      ;

      Morelli, Luca

      ;

      Vokáčová, Klára

      ;

      Pasquali, Claudio

      ;

      Lawlor, Rita T

      ;

      Bazzocchi, Francesca

      ;

      Kupcinskas, Juozas

      ;

      Capurso, Gabriele

      ;

      Campa, Daniele

      ;

      Canzian, Federico

      2024

      ,

      Human Genomics

      ,

      18

      (February)

      Genome-wide association studies (GWAS) are a powerful tool for detecting variants associated with complex traits and can help risk stratification and prevention strategies against pancreatic ductal adenocarcinoma (PDAC). ...

    • Haplotype analysis identifies functional elements in monoclonal gammopathy of unknown significance 

      original article

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      published version

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      Thomsen, Hauke

      ;

      Chattopadhyay, Subhayan

      ;

      Weinhold, Niels

      ;

      Vodička, Pavel

      ;

      Vodičková, Ludmila

      ;

      Hoffmann, Per

      ;

      Nöthen, Markus M

      ;

      Jöckel, Karl-Heinz

      ;

      Schmidt, Börge

      ;

      Hajek, Roman

      ;

      Hallmans, Göran

      ;

      Pettersson-Kymmer, Ulrika

      ;

      Späth, Florentin

      ;

      Goldschmidt, Hartmut

      ;

      Hemminki, Kari Jussi

      ;

      Försti, Asta

      2024

      ,

      Blood Cancer Journal

      ,

      14

      (1)

      Genome-wide association studies (GWASs) based on common single nucleotide polymorphisms (SNPs) have identified several loci associated with the risk of monoclonal gammopathy of unknown significance (MGUS), a precursor ...

    • Survival improvements in esophageal and gastric cancers in the Nordic countries favor younger patients 

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      Hemminki, Kari Jussi

      ;

      Zitrický, František

      ;

      Foersti, Asta

      ;

      Hemminki, Otto

      ;

      Liška, Václav

      ;

      Hemminki, Akseli

      2024

      ,

      Cancer Medicine

      ,

      13

      (15)

      Esophageal cancer (EC) and gastric cancer (GC) are fatal cancers with a relatively late age of onset. Age is a negative risk factor for survival in many cancers and our aim was to analyze age-specific survival in EC and ...

    • Survival in oral and pharyngeal cancers is catching up with laryngeal cancer in the NORDIC countries through a half century 

      original article

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      Zitrický, František

      ;

      Koskinen, Anni I.

      ;

      Hemminki, Otto

      ;

      Försti, Asta

      ;

      Hemminki, Akseli

      ;

      Hemminki, Kari Jussi

      2024

      ,

      Cancer Medicine

      ,

      13

      (1)

      Background: Cancers of the head and neck (HN) are heterogeneous tumors with incidence rates varying globally. In Northern Europe oral and oropharyngeal cancers are the most common individual types. Survival for HN varies ...

    • Survival in Elderly Ovarian Cancer Remains Challenging in the Nordic Countries 

      original article

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      Hemminki, Kari Jussi

      ;

      Zitrický, František

      ;

      Försti, Asta

      ;

      Hemminki, Akseli

      2024

      ,

      Cancers

      ,

      16

      (12)

      BACKGROUND: Despite treatment having improved through intensive surgical procedures and chemotherapy-and more recently, targeted therapies-ovarian cancer is the most fatal female cancer. As such, we wanted to analyze ...

    • Does virtual reality allow for a reliable assessment of reaction speed in mixed martial arts athletes? 

      original article

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      published version

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      Polechonski, Jacek

      ;

      Langer, Alan

      ;

      Šťastný, Petr

      ;

      Zak, Marcin

      ;

      Zajac-Gawlak, Izabela

      ;

      Maszczyk, Adam

      2024

      ,

      Baltic Journal of Health and Physical Activity

      ,

      16

      (3)

      Introduction: The immersive virtual reality (VR) might bring a new reliable approach to diagnosing motor abilities. Therefore, the main goal of this research was to check the intertrial reliability and diagnostic possibility ...

    • Learnability of state spaces of physical systems is undecidable 

      original article

      embargoed access

      published version

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      Špelda, Petr

      ;

      Střítecký, Vít

      2024

      ,

      Journal of Computational Science

      ,

      83

      (December 2024)

      Despite an increasing role of machine learning in science, there is a lack of results on limits of empirical exploration aided by machine learning. In this paper, we construct one such limit by proving undecidability of ...

    • Secukinumab Causing Medication-Related Osteonecrosis of the Jaw, in a Patient Diagnosed with Psoriasis and Rheumatoid Arthritis 

      casuistics

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      Hauer, Lukáš

      ;

      Moztarzadeh, Omid

      ;

      Baghalipour, Nasimeh

      ;

      Genčur, Jiří

      2024

      ,

      Psoriasis

      ,

      14

      (23 September 2024)

      The use of antiangiogenic and antiresorptive medications, particularly in patients with cancer or osteoporosis, can lead to osteonecrosis of the jaw following tooth extraction, trauma or arising spontaneously- A condition ...

    • Genetic And Environmental Associations Of Nonspecific Chromosomal Aberrations 

      summarizing article

      restricted access

      published version

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      Hemminki, Kari Jussi

      ;

      Niazi, Yasmeen

      ;

      Vodičková, Ludmila

      ;

      Vodička, Pavel

      ;

      Försti, Asta

      2024

      ,

      Mutagenesis

      Nonspecific structural chromosomal aberrations (CAs) are found in around 1% of circulating lymphocytes from healthy individuals but the frequency may be higher after exposure to carcinogenic chemicals or radiation. CAs ...

    • Social Mobility of Elites in East-Central Europe in Historical Perspective 

      chapter in a collective monograph

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      published version

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      Popovici, Vlad

      ;

      Velková, Alice

      ;

      Klečacký, Martin

      2024

      ,

      Oldenbourg

      ,

      Walter de Gruyter GmbH

      ,

      Climbing up the Social Ladder? Social Mobility of Elites in East-Central Europe in the Long 19th Century

      The chapter discusses the concept of the social mobility and illustrates how historians of modern-time elites in Central and Eastern Europe coneptualize and approach social mobility in conjunction with the more conventional ...