Repozitář publikační činnosti UK: Poslední příspěvky
Zobrazují se záznamy 1-20 z 1143
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Local diversity of soil forming processes in the semi-arid tropics and its environmental drivers: An example from Otavi Mountains, northern Namibia
původní článek
open access
vydavatelská verze
2025
,Catena
,249
(February)
Local diversity of soil units and properties in a semi-arid tropical climate is controlled by a number of interacting factors, whose contribution to the final form of individual soil characteristics is often difficult to ...
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Clinical Features, Outcomes, and Response to Corticosteroid Treatment of Acute Tubulointerstitial Nephritis: A Single-Centre Retrospective Cohort Study in the Czech Republic
původní článek
open access
vydavatelská verze
2024
,Kidney & Blood Pressure Research
,49
(1)
Introduction: Acute tubulointerstitial nephritis (ATIN) is a well-recognized cause of acute kidney injury (AKI) due to the tubulointerstitial inflammation. The aim of this study was to explore the clinical features, outcomes, ...
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Arsenic bioaccessibility in environmentally important arsenic minerals
původní článek
open access
vydavatelská verze
2025
,Journal of Hazardous Materials
,485
(March)
The potential risk to humans from incidental ingestion of As-contaminated soil and mine waste is influenced by the mineralogical composition of the As phases present. Using the Solubility Bioaccessibility Research Consortium ...
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Health Problems of Civilization Physical activity: diseases and issues recognized by the WHO
původní článek
open access
vydavatelská verze
2024
,Health Problems of Civilization
,18
(2)
Background. The aim of the work was to ascertain the differences in the temporal characteristics of the gait cycle of slow walking in high heels. The study particularly focusedon a group of women who started to wear high ...
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Metabolism of primary high-grade serous ovarian carcinoma (HGSOC) cells under limited glutamine or glucose availability
původní článek
open access
vydavatelská verze
2024
,Cancer & Metabolism
,12
(September)
BackgroundHigh-grade serous ovarian carcinoma (HGSOC) is the most common and aggressive subtype of epithelial ovarian carcinoma. It is primarily diagnosed at stage III or IV when the 5-year survival rate ranges between 20% ...
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Compensatory exercises for young cyclists in the pubescents
původní článek
open access
vydavatelská verze
2024
,Physical Activity Review
,12
(1)
The aim of the study was to evaluate the state of the musculoskeletal system of selectedcyclists and to propose appropriate compensatory exercises, the effects of which were verified inpractice. Twenty-eight MTB cyclists ...
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Revising pathogenesis of AP1S1-related MEDNIK syndrome: a missense variant in the AP1S1 gene as a causal genetic lesion
původní článek
open access
vydavatelská verze
2024
,Journal of Molecular Medicine
,102
(11)
MEDNIK syndrome is a rare autosomal recessive disease characterized by mental retardation, enteropathy, deafness, peripheral neuropathy, ichthyosis, and keratoderma, and caused by variants in the adaptor-related protein ...
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Distinct pattern of genomic breakpoints in CML and BCR::ABL1-positive ALL: analysis of 971 patients
původní článek
open access
vydavatelská verze
2024
,Molecular Cancer
,23
(1)
BACKGROUND: The BCR::ABL1 is a hallmark of chronic myeloid leukemia (CML) and is also found in acute lymphoblastic leukemia (ALL). Most genomic breaks on the BCR side occur in two regions - Major and minor - leading to ...
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Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase
původní článek
open access
vydavatelská verze
2024
,Cancer Letters
,605
(November)
Tumor cells often adapt to amino acid deprivation through metabolic rewiring, compensating for the loss with alternative amino acids/substrates. We have described such a scenario in leukemic cells treated with L-asparaginase ...
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Mouse polyomavirus infection induces lamin reorganisation
původní článek
open access
vydavatelská verze
2024
,FEBS Journal
,291
(23)
The nuclear lamina is a dense network of intermediate filaments beneath the inner nuclear membrane. Composed of A-type lamins (lamin A/C) and B-type lamins (lamins B1 and B2), the nuclear lamina provides a scaffold for the ...
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Italian peninsula as a hybridization zone of Ixodes inopinatus and I. ricinus and the prevalence of tick-borne pathogens in I. inopinatus, I. ricinus, and their hybrids
původní článek
open access
vydavatelská verze
2024
,Parasites & Vectors
,17
(1)
BACKGROUND: Ixodes inopinatus was described from Spain on the basis of morphology and partial sequencing of 16S ribosomal DNA. However, several studies suggested that morphological differences between I. inopinatus and ...
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Toscana virus – finding the new vectors
jiný příspěvek v konferenčním sborníku
open access
vydavatelská verze
2024
,New Orleans
,American Society of Tropical Medicine and Hygiene
,ASTMH Abstract Book 2024
,2024
Arbovirus Phlebovirus toscanaense (TOSV) is an emerging but still neglected human pathogen that circulates in countries around the Mediterranean Sea. The manifestation of the disease varies from non-symptomatic forms through ...
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Religious-secular as non-competitive: Encouraging participative church in a Czech Catholic diocese
původní článek
embargo
vydavatelská verze
2024
,Social Compass
,71
(2)
The presented text builds upon 4 years of applied research intended to support the transformation of a Czech Catholic diocese into a more participative organisation, internally and externally. This process allowed us to ...
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Understanding users’ responses to disclosed vs. undisclosed customer service chatbots: a mixed methods study
původní článek
embargo
vydavatelská verze
2024
,AI & Society
,39
(6)
Due to huge advancements in natural language processing (NLP) and machine learning, chatbots are gaining significance in the field of customer service. For users, it may be hard to distinguish whether they are communicating ...
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Mouse PML protein isoforms and their role in innate antiviral immunity
abstrakt v elektronické podobě
open access
postprint
2024
Promyelocytic leukaemia nuclear bodies (PML NBs) are dynamic, multiprotein, membrane-less structures composed of the main scaffold PML protein and various stable or transient partner proteins. Beyond their diverse endogenous ...
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ASPH inhibition reveals differential gene expression patterns in HPV-positive and HPV-negative cell lines
abstrakt v elektronické podobě
open access
preprint
2024
,Boston
Cancer is associated with alterations in key cellular pathways, including the aspartate β-hydroxylase (ASPH) pathway. ASPH is an oncogene upregulated in various carcinomas, playing a vital role in tumor progression and ...
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The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization
původní článek
open access
vydavatelská verze
2024
,PLoS Genetics
,20
(12)
The RNA content is crucial for the formation of nuclear compartments, such as nuclear speckles and nucleoli. Phosphatidylinositol 4,5-bisphosphate (PIP2) is found in nuclear speckles, nucleoli, and nuclear lipid islets and ...
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Investigating antibacterial and anti-inflammatory properties of synthetic curcuminoids
původní článek
open access
vydavatelská verze
2024
,Frontiers in Medicine
,11
(October)
The concept of intratumoral microbiota is gaining attention in current research. Tumor-associated microbiota can activate oncogenic signaling pathways such as NF-kappa B, thereby promoting tumor development and progression. ...
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The perinucleolar compartment and the oncogenic super-enhancers are part of the same phase-separated structure filled with phosphatidylinositol 4,5bisphosphate and long noncoding RNA HANR
původní článek
open access
vydavatelská verze
2024
,Advances in Biological Regulation
,AHEAD OF PRINT
(Available online 30 November 2024)
The liquid-liquid phase separation in the cell nucleus regulates various processes such as gene regulation and transcription control, chromatin organization, and DNA repair. A plethora of proteins and RNAs contribute to ...
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The long-term impact of biogenic volatile organic compound emissions on urban ozone patterns over central Europe: contributions from urban and rural vegetation
původní článek
open access
vydavatelská verze
2024
,Atmospheric Chemistry and Physics
,24
(10. 12. 2024)
The impact of biogenic emissions of hydrocarbons from vegetation on ozone, as well as on overall oxidative capacity of air, is analyzed for central European cities for a present-day period using a chemistry transport model. ...
