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  • UV-C irradiation as an effective tool for sterilization of porcine chimeric VP1-PCV2bCap recombinant vaccine 

    Vrablikova, Alena; Fojtikova, Martina; Hezova, Renata; Simeckova, Pavlina; Brezani, Veronika; Strakova, Nicol; Fraiberk, Martin; Kotoucek, Jan; Masek, Josef; Psikal, Ivan (2023)
    Ultraviolet irradiation is an effective method of virus and bacteria inactivation. The dose of UV-C light necessary for baculovirus inactivation by measurement of fluorescent GFP protein produced by baculovirus expression ...
  • Hepatitis B virus hijacks host E2/E3 ubiquitin ligase, UBE2O, for viral nucleocapsid assembly and virion egress 

    Lubyová, Barbora; Tikalová, Eva; Janovec, Václav; Rjabčenko, Boris; Krulová, Kristýna; Huerfano Meneses, Sandra; Hirsch, Ivan; Weber, Jan (Praha, Praha, 2024)
    Chronic hepatitis B (CHB) represents a serious liver disease that is caused by infection of Hepatitis Bvirus (HBV). CHB is associated with severe liver conditions ranging from fibrosis and cirrhosis tohepatocellular carcinoma ...
  • Aristotelés o studu a ctnosti 

    Synek, Stanislav (2023)
    Článek se zabývá problematickými aspekty Aristotelova pojetí studu (aidós) a jeho vztahem ke ctnosti. Stud je Aristotelem na jedné straně představen jako specifická emoce (pathé), na straně druhé však zároveň jako "střednost" ...
  • Effect of ADAR1 enzyme knockout on HCV replication 

    Kubů, Martin; Pospíšek, Martin; Vopálenský, Václav; Roučová, Kristina (Česká zemědělská univerzita, Praha, 2024)
    The hepatitis C virus (HCV) is a member of the Flaviviridae family whose genome consists of a +RNAmolecule. It causes hepatitis C, a disease that affects tens of millions of people worldwide. Althoughthere is an effective ...
  • Inhibition of HBsAg secretion by a novel autophagy inducer 

    Pimková Polidarová, Markéta; Janovec, Václav; Berehovska, Olena; Kůtová, Zuzana; Sedláček, Jindřich; Adámek, Michael; Machara, Aleš; Hirsch, Ivan; Grantz Šašková, Klára (Česká zemědělská univerzita v Praze, Praha, 2024)
    Chronic hepatitis B (CHB) is a viral liver infection caused by hepatitis B virus (HBV), affecting over 300 million people world-wide. Untreated CHB can lead to liver cirrhosis and hepatocellular carcinoma, causing over ...

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