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Recently Added
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Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy
(2023)Cyclic dinucleotides (CDNs) trigger the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, which plays a key role in cytosolic DNA sensing and thus in immunomodulation against infections, cell ... -
The crystal structure of bis(1H-pyrazole-carboxamidine-κN,N′)bis(nitrato-κO)-copper(II), C8H12CuN10O6
(2023)C8H12CuN10O6, triclinic, P1 (no. 2), a = 7.6063(5) Å, b = 9.3072(7) Å, c = 10.8485(8) Å, alpha = 81.370(2)°, beta = 75.503(2)°, gamma = 84.756(2)° V = 733.97(9) Å(3), Z = 2, R-gt(F) = 0.0515, wR(ref)(F-2) = 0.1194, T =120(2) K. -
Minimal residual disease in BCR::ABL1-positive acute lymphoblastic leukemia: different significance in typical ALL and in CML-like disease
(2022)Recently, we defined "CML-like" subtype of BCR::ABL1-positive acute lymphoblastic leukemia (ALL), resembling lymphoid blast crisis of chronic myeloid leukemia (CML). Here we retrospectively analyzed prognostic relevance ... -
Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy
(2023)L-asparaginase (ASNase), the drug included on the World Health Organization's List of EssentialMedicines, is irreplaceable in the front-line treatment of childhood acute lymphoblastic leukemia(ALL)1 . However, the relapse ... -
Ludwig von MISES: Socialismus: ekonomická a sociologická analýza
(2023)Reflexe hospodářsko-historické analýzy socialistického systému. Zamyšlení nad jejím možným využitím historickou obcí v současné době.