Repozitář publikační činnosti UK: Poslední příspěvky
Zobrazují se záznamy 221-240 z 1809
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Comparison of Different Sensor Locations on Freezing-of-Gait Ratio Results
původní článek
open access
vydavatelská verze
2025
,IRBM
,46
(2)
Background: Freezing of gait (FoG) is a walking disturbance in the Parkinson's disease (PD). The freezing ratio (FoG-ratio) is a parameter used to quantify overall freezing severity rather than to assess single freezing ...
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Clinical risk stratification: Prague validation of the DAAE score, a clinical tool for estimating risk of disesase progression in multiple sclerosis
původní článek
open access
vydavatelská verze
2025
,Multiple Sclerosis and Related Disorders
,98
(June)
Background: Secondary progressive MS is associated with a worse prognosis, warranting the need for early predictive tools. The DAAE score estimates the five-year risk of transition to clinical diagnosis of SPMS, showing a ...
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Abnormal neuronal activity in the subthalamic nucleus contributes to dysarthria in patients with Parkinson's disease
původní článek
open access
vydavatelská verze
2025
,Neurobiology of Disease
,207
(April)
Background: This study investigated the subthalamic nucleus (STN) function and deep brain stimulation (DBS) effects on single-unit activity (SUA) in Parkinson's disease (PD) patients with dysarthria. Methods: After presurgical ...
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Unravelling head tremor mechanisms: insights from speech analysis in essential tremor and cervical dystonia
původní článek
open access
vydavatelská verze
2025
,Springer
,Journal of Neural Transmission
,132
(8)
Head tremor is a common symptom in both essential tremor (ET) and cervical dystonia (CD). Distinguishing between these two conditions can be challenging in clinical practice, particularly when head tremor is the dominant ...
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Deep Brain Stimulation for VPS16-Related Dystonia: A Multicenter Study
původní článek
open access
vydavatelská verze
2025
,American Neurological Association
,Annals of Neurology
,98
(4)
Objective: The objective was to evaluate the effects of deep brain stimulation (DBS) in an international cohort of patients with VPS16-related dystonia. Methods: This observational study collected preoperative and postoperative ...
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Nutritional and Clinical Status of Czech Adolescents with Anorexia Nervosa before and during the SARS-CoV-2 Pandemic
původní článek
open access
vydavatelská verze
2025
,Bratislavské lekárske listy / Bratislava Medical Journal
,126
(4)
Objectives: This study assessed the nutritional and clinical status of Czech adolescents with anorexia nervosa (AN) during the SARS-CoV-2 pandemic (3/2020-3/2022), comparing them with those diagnosed before the pandemic ...
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Legislative Turnover in Latin America: Introducing a New Dataset and Analyzing Its Temporal Dynamics
původní článek
open access
vydavatelská verze
2025
,Blackwell Publishing
,Latin American Politics and Society
,67
(3)
The article examines the patterns of turnover of Latin American legislators. It contributes (1) by introducing a large original dataset of turnover rates in 204 elections between 1985 and 2023 based on manually coded lists ...
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mHealth-assisted expiratory muscle strength training in Parkinson's disease patients: A proof-of-concept study
původní článek
open access
vydavatelská verze
2024
,IOS Press
,Journal of Parkinson's Disease
,14
(8)
Background: Expiratory muscle strength training (EMST) is acknowledged for its therapeutic benefits in Parkinson's disease (PD), yet long-term adherence remains a challenge. Objective: The primary aim of this study was to ...
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Heat Shock Protein Network: the Mode of Action, the Role in Protein Folding and Human Pathologies
přehledový článek
open access
vydavatelská verze
2024
,Univerzita Karlova v Praze, 1. lékařská fakulta
,Folia Biologica
,70
(3)
Protein folding is an extremely complicated process, which has been extensively tackled during the last decades. In vivo, a certain molecular machinery is responsible for assisting the correct folding of proteins and ...
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Novel activity assay for botulotoxin A1 detection using functionalized chips and matrix-assisted laser desorption/ionization mass spectrometry
přehledový článek
open access
vydavatelská verze
2025
,Taylor & Francis Ltd
,Expert Review of Proteomics
,22
(4)
Background: Botulinum neurotoxins (BoNTs) are a group of neurotoxins produced by Clostridium bacteria. Their effect on neuro-muscular connections through cleaving proteins of the SNARE complex results in blocking acetylcholine ...
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Structural Connectivity of the Substantia Nigra: A Comprehensive Review of Diffusion Imaging and Tractography Studies
přehledový článek
open access
vydavatelská verze
2025
,Applied Sciences
,15
(14)
The substantia nigra (SN) has historically been regarded as a pivotal element of the brain's motor circuits, notably within the context of the nigrostriatal pathway and Parkinson's disease. However, recent advancements in ...
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A new performance based measure of activities of daily living: Pilot study of the Night Out Task Czech version
původní článek
open access
vydavatelská verze
2025
,E-psychologie
,18
(4)
In the Czech Republic, a naturalistic performance measure for assessing instrumental activities of daily living (IADL) has not yet been implemented. The present study aims to adapt such a method, the Night Out Task (NOT), ...
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Synthesis and evaluation of cyclobut-3-ene-1,2-dione-3-hydrazones with benzothiazole moiety as novel anticancer agents inducing nonapoptotic oncosis-like cell death
původní článek
open access
vydavatelská verze
2025
,Elsevier
,Biomedicine & Pharmacotherapy
,190
(September)
We report the design, synthesis, and biological evaluation of novel hybrid anticancer agents bearing three pharmacophores in one molecule: benzothiazole, cyclobut-2-ene-1,2-dione and hydrazone moieties. Several derivatives ...
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Breakfast clubs in the Czech Republic: food security, socialisation, education, or participation? The evolution of intervention goals
původní článek
open access
vydavatelská verze
2025
,Springer Nature
,Humanities & Social Sciences Communications
,12
(11 June 2025)
This study examines the implementation of breakfast clubs across all the Czech schools that opted for this intervention under an EU-funded programme aimed at supporting socioeconomically disadvantaged students. Schools ...
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Trojice subžánrů moderního českého románu prizmatem postavy
Three subgenres of the modern Czech novel through the prism of character
recenze
open access
vydavatelská verze
2025
,Ústav pro českou literaturu Akademie věd České republiky v.v.i.
,Česká literatura
,73
(1)
Recenze publikace: Kudlová, Klára. Čas, postavy, román: na přelomu tisíciletí. First edition. Brno: Ústav pro českou literaturu AV ČR, 2023. 212 pages. Teoretická knihovna; 40. ISBN 978-80-275-1589-9.
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Impact of pollution on the temperature sensitivity of multiple Norway spruce tree-ring parameters in Central Europe
původní článek
open access
vydavatelská verze
2025
,Elsevier Ltd.
,Agricultural and Forest Meteorology
,372
(7 July 2025)
Central European forests experienced high rates of air pollution in the second half of the 20th century, especially along the borders of Czechia, Germany and Poland. Consequently, tree-growth declines were detected in ...
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Sociogeografická regionalizace Česka 2021: změna v regionálním vývoji nebo přechodná stabilizace?
Sociogeographic regionalisation of Czechia 2021: Changes in regional development or temporary stabilisation?
původní článek
open access
vydavatelská verze
2025
,Česká geografická společnost z.s.
,Geografie: Sborník České geografické společnosti
,130
(2)
Sociogeografická regionalizace je významným tématem díky novým datům, novým technologiím a neustálým požadavkům plánovací praxe. Článek představuje hlavní výsledky sociogeografické regionalizace Česka podle metodiky M. ...
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Questioning post-socialism in urban studies? Don't shoot ourselves in the foot
původní článek
open access
vydavatelská verze
2025
,Taylor & Francis
,Eurasian Geography and Economics
,66
(6)
This Commentary discusses the concepts of post-socialism and the post-socialist city in urban studies and human geography, examining their analytical and normative potential for understanding societal and spatial transformations ...
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Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles
původní článek
open access
vydavatelská verze
2025
,Scientific Data
,12
(1)
Roadkill is widely recognized as one of the primary negative effects of roads on many wildlife species and also has socioeconomic impacts when they result in accidents. A comprehensive dataset of roadkill locations is ...
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Advanced polymer nanofibers for the online extraction coupled with liquid chromatography for the determination of emerging fluorinated contaminants in surface water
původní článek
open access
vydavatelská verze
2026
,Elsevier B.V.
,Talanta
,298
(February 2026)
Advanced polyacrylonitrile, polypropylene, polyhydroxybutyrate, polycaprolactone, and poly(vinylidene difluoride) nanofibers, including composite materials containing carbon nanoparticle additives, combined micro/nanofibers, ...
