Now showing items 421-440 of 938

    • Population-Attributable Fractions of Personal Comorbidities for Liver, Gallbladder, and Bile Duct Cancers 

      original article

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      Hemminki, Kari Jussi

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      Sundquist, Kristina

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      Sundquist, Jan

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      Foersti, Asta

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      Liška, Václav

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      Hemminki, Akseli

      ;

      Li, Xinjun

      2023

      ,

      Cancers

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      15

      (12)

      Simple Summary Liver cancer is often used as a general term for cancers of the liver (hepatocellular carcinoma, HCC), the gallbladder, and the bile ducts. The well-known risk factors are alcohol and viral hepatitis, but ...

    • Association of lncRNA and transcriptome intersections with response to targeted therapy in metastatic renal cell carcinoma 

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      Tesařová, Tereza

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      Koucká, Kamila

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      Václavíková, Radka

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      Šeborová, Karolína

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      Hora, Milan

      ;

      Hes, Ondřej

      ;

      Pivovarčíková, Kristýna

      ;

      Souček, Pavel

      ;

      Fiala, Ondřej

      2023

      ,

      Oncology Letters

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      26

      (3)

      Long non-coding RNAs (lncRNAs) serve an important role in cancer progression and may be used as efficient molecular biomarkers. The present study aimed to identify lncRNAs associated with the response to the receptor ...

    • A Fecal MicroRNA Signature by Small RNA Sequencing Accurately Distinguishes Colorectal Cancers: Results From a Multicenter Study 

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      Pardini, Barbara

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      Ferrero, Giulio

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      Tarallo, Sonia

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      Gallo, Gaetano

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      Francavilla, Antonio

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      Licheri, Nicola

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      Trompetto, Mario

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      Clerico, Giuseppe

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      Senore, Carlo

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      Peyre, Sergio

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      Vymetálková, Veronika

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      Vodičková, Ludmila

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      Liška, Václav

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      Vyčítal, Ondřej

      ;

      Levý, Miroslav

      ;

      Macinga, Peter

      ;

      Hucl, Tomas

      ;

      Budinska, Eva

      ;

      Vodička, Pavel

      ;

      Cordero, Francesca

      ;

      Naccarati, Alessio

      2023

      ,

      Gastroenterology

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      165

      (3)

      BACKGROUND & AIMS: Fecal tests currently used for colorectal cancer (CRC) screening show limited accuracy in detecting early tumors or precancerous lesions. In this respect, we comprehensively evaluated stool microRNA ...

    • miRNA and lncRNA as Potential Tissue Biomarkers in Hepatocellular Carcinoma 

      summarizing article

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      Mallela, Venkata Ramana

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      Rajtmajerová, Marie

      ;

      Trailin, Andriy

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      Liška, Václav

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      Hemminki, Kari Jussi

      ;

      Ambrożkiewicz, Filip

      2024

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      Non-coding RNA Research

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      9

      (1)

      Hepatocellular carcinoma (HCC) is primary liver cancer, frequently diagnosed at advanced stages with limited therapeutic options. MicroRNAs (miRNAs) regulate target gene expression and through inhibitory competitive binding ...

    • Serious Immune-related Adverse Events Are Associated With Greater Efficacy of Nivolumab Therapy Against Non-small Cell Lung Cancer 

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      Blažek, Jiří

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      Hošek, Petr

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      Hrabcova, Karolina

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      Bratova, Monika

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      Kultan, Juraj

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      Hrnčiarik, Michal

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      Černovská, Markéta

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      Zemanová, Petra

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      Krejčí, Jana

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      Koubková, Leona

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      Stastny, Marek

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      Svatoň, Martin

      2023

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      In Vivo

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      37

      (5)

      BACKGROUND/AIM: The aim of this study was to investigate possible association between adverse events of nivolumab therapy and the effectiveness of treatment in patients with non-small cell lung cancer (NSCLC). Focusing on ...

    • Branchioma with a nested/organoid morphology: molecular profiling of a distinctive potentially misleading variant and reappraisal of potential relationship to CD34-positive/Rb1-deficient tumors of the neck 

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      Baněčková, Martina

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      Michal, Michael

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      Vanecek, Tomas

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      Grossman, Petr

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      Nikolov, Dimitar Hadzi

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      Vcelak, Radek

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      Zalud, Radim

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      Michal, Michal

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      Agaimy, Abbas

      2023

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      Virchows Archiv

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      483

      (4)

      Branchioma (previously called ectopic hamartomatous thymoma, branchial anlage mixed tumor, or thymic anlage tumor) is a rare lower neck lesion with an adult male predominance and an uncertain histogenesis. Except for 4 ...

    • Prognostic potential of whole exome sequencing in the clinical management of metachronous colorectal cancer liver metastases 

      original article

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      Heczko, Lucie

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      Hlaváč, Viktor

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      Holý, Petr

      ;

      Dvořák, Pavel

      ;

      Liška, Václav

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      Vyčítal, Ondřej

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      Fiala, Ondřej

      ;

      Souček, Pavel

      2023

      ,

      Cancer Cell International

      ,

      23

      (1)

      Background: Colorectal cancer is a highly prevalent and deadly. The most common metastatic site is the liver. We performed a whole exome sequencing analysis of a series of metachronous colorectal cancer liver metastases ...

    • Využití tepové frekvence k optimalizaci rozvoje vytrvalosti 

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      Busta, Jan

      2023

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      Pádler : vodácký magazín

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      8

      (4)

      Článek seznamuje čtenáře s možnostmi využití tepové frekvence v kondičním i speciálním tréninku kanoistů.

    • Morphology of canoe slalom and canoe sprint female competitors 

      poster

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      Busta, Jan

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      Tulachová, Johana

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      Hellebrand, Jaroslav

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      Vajda, Matej

      2023

      This poster presents a comparison of anthropometric and body composition parameters between female performance athletes in canoe slalom and canoe sprint.

    • Morphology Differences Between Elite C1 and K1 Canoe Slalom Competitors 

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      Busta, Jan

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      Hellebrand, Jaroslav

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      Kinkorová, Ivana

      ;

      Macas, Tomáš

      2022

      Introduction: Anthropometric and strength parameters are important factors of the white water slalom performance. However, differences between kayak (K1) and canoe (C1) category are still unknown. The aim of this study is ...

    • Discovery of Small Molecule Activators of NRF1 Transcriptional Activity Preventing Protein Aggregation 

      abstract in conference proceedings

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      Kůtová, Zuzana

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      Sedláček, Jindřich

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      Adámek, Michael

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      Šubová, Dominika

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      Majer, Pavel

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      Svobodová, Lucie

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      Kadlecová, Alena

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      Machara, Aleš

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      Grantz Šašková, Klára

      2023

      The intracellular accumulation of abnormal proteins exceeding their degradation can cause imbalance in proteostasis resulting in proteotoxic stress that leads to severe pathological stages. This state relates to proteasome ...

    • Výživové suplementace pro kanoistické sporty 

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      Busta, Jan

      2022

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      Pádler : vodácký magazín

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      7

      (3)

      Článek navrhuje konkrétní doplňky výživy pro výkonnostní a vrcholové kanoisty. Je součástí čtyřdílné série popularizujících článků směřujících k vyšší výkonnosti nejen vrcholových sportovců.

    • Zimní kondiční příprava 

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      Busta, Jan

      2022

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      Pádler

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      7

      (4)

      V článku je představena modelová zimní kondiční příprava pro sportovce kanoistických disciplín.

    • Psychologická příprava 

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      Busta, Jan

      2022

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      Pádler : vodácký magazín

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      7

      (2)

      Článek se zabývá psychologickou přípravou ve vodním slalomu. Navrhuje vhodné metoda rozvoje psychických determinant výkonu ve vodním slalomu i dalších kanoistických sportech.

    • ‚I will not be a mere wreath layer!‘ Analysis of the presidential refusal to appoint cabinet ministers in the Czech Republic 

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      Michal, Aleš

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      Malý, Michal

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      Hrebenár, Petr

      2023

      ,

      Acta Politologica

      ,

      2023

      (15)

      The discrepancy between the constitutionally defined and actual exercise of the power ofstate institutions has been widely discussed within European political science. The adop- tion of direct presidential elections in the ...

    • The Dynamics of Postnominal Adjectives in Middle English 

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      Volná, Veronika

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      Šaldová, Pavlína

      2022

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      Anglica. An International Journal of English Studies

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      31

      (2)

      Middle English was a period of transition between the free word order of Old English, with functional variation of adjective form and position with respect to the head noun, and the fixed prenominal placement of single ...

    • Embodying Agonism in Lucy Kirkwood’s Mosquitoes and The Welkin 

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      Wallace, Clare

      2022

      ,

      Litteraria Pragensia: Studies in Literature and Culture

      ,

      32

      (63)

      Rooted in Chantal Mouffe's conceptualisation of agonistic pluralism and Jacques Rancière's work on dissensus, this article analyses the debate scenes of British playwright Lucy Kirkwood's plays: Mosquitoes (2017) and The ...

    • La haine de la littérature selon Bernard Lamy 

      The Hatred of Literature according to Bernard Lamy

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      Šuman, Záviš

      2022

      ,

      Svět literatury [online]

      ,

      32

      (06/2022)

      L'article se concentre sur les réflexions de Lamy sur la fiction littéraire et le théâtre telles qu'elles sont exposées dans ses Nouvelles Réflexions sur l'art poétique (1678). Bernard Lamy (1640-1715) était un écrivain ...

    • MERGING PROFESSIONAL AND COLLABORATIVE LEXICOGRAPHY: THE CASE OF CZECH NEOLOGY 

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      Škrabal, Michal

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      Kavka, Martin

      2021

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      International Journal of Lexicography

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      34

      (3)

      This paper aims to relate two linguistic phenomena: neology (along with sources for its study) and collaborative lexicography. A pair of case studies is presented concerning two thematically defined groups of recent Czech ...

    • The Corpus of Contemporary Czech Poetry: A database for research on contemporary poetic language across media 

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      Škrabal, Michal

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      Piorecký, Karel

      2022

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      Digital Scholarship in the Humanities

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      37

      (4)

      Our article reports on the emerging Corpus of Contemporary Czech Poetry and the possibilities for its use. We describe the genesis of the idea of creating a specific corpus that combines the principles of synchronicity and ...