Repozitář publikační činnosti UK: Poslední příspěvky
Zobrazují se záznamy 1841-1860 z 1869
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Methodological guidelines for open access and self-archiving at Charles University : Methodological guidelines for open access coordinators
Metodika open access a autoarchivace na Univerzitě Karlově : Metodika pro koordinátory open access
necertifikovaná metodika
open access
draft
2022
,Praha
,Univerzita Karlova, Ústřední knihovna
Methodological guidelines for open access and self-archiving at Charles University : Methodological guidelines for open access coordinators is a document intended for CU employees (open access coordinators) who, in the OBD ...
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Pracovní právo a sociální ochrana v nejisté době
Labor law and social protection in uncertain times
sborník
embargo
vydavatelská verze
2022
,Praha
,Univerzita Karlova, Právnická fakulta
Kniha se zabývá aktuálním otázkami pracovního práva a sociální ochrany
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Lékaři 2022 aneb specializační vzdělávání očima lékařů
příručka
open access
vydavatelská verze
2023
,Praha
,Univerzita Karlova, 3. lékařská fakulta
Průzkum je pokusem o to, aby byl slyšet hlas těch, kteří se specializačního vzdělávání přímo účastní. Je možné, že některé jeho části budou vnímány velmi problematicky či vzbudí řadu emocí. Byli bychom ale neradi, aby byl ...
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Improving the antimicrobial activity of old antibacterial drug mafenide: Schiff bases and their bioactivity targeting resistant pathogens
původní článek
open access
vydavatelská verze
2023
,Future Medicinal Chemistry
,15
(3)
Background: Increasing rates of acquired resistance have justified the critical need for novel antimicrobial drugs. One viable concept is the modification of known drugs. Methods & results: 21 mafenide-based compounds were ...
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The demand side of vaccine politics and pandemic illiberalism
původní článek
open access
vydavatelská verze
2022
,East European Politics
,38
(4)
We take the demand-side perspective of Sputnik V, trying to answer why facing vaccine scarcity, some countries opt for Sputnik V, and others do not. To show how the pandemic tests the institutional safeguards and soft ...
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Role of actors in the processes of sustainable development at local level – experiences from the Czech Republic
původní článek
open access
vydavatelská verze
2022
,Frontiers in Sustainability [online]
,3
(07 July 2022)
In this text we are interested in the preconditions for, and opportunities provided by sustainable development at local level in non-metropolitan areas, i. e., in rural areas and villages. These areas are generally seen ...
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Local Action Groups and sustainable development agenda: Case study of regional perspectives from Czechia
původní článek
open access
vydavatelská verze
2022
,Frontiers in Sustainability [online]
,3
(22 July 2022)
The United Nations' 2030 Agenda for Sustainable Development is generally accepted as an overarching framework to cope with various global challenges. Many of them are manifested locally and need to be solved at the regional ...
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Engine shutdown: Migrastatic strategies and prevention of metastases
přehledový článek
embargo
vydavatelská verze
2023
,Trends in Cancer
,9
(4)
Most cancer-related deaths among patients with solid tumors are caused by metastases. Migrastatic strategies represent a unique therapeutic approach to prevent all forms of cancer cell migration and invasion. Because the ...
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Publication and Attenuation Biases in Measuring Skill Substitution
původní článek
embargo
preprint
2024
,Review of Economics and Statistics
,106
(5)
A key parameter in the analysis of wage inequality is the elasticity of substitution between skilled and unskilled labor. We show that the empirical literature is consistent with both publication and attenuation bias in ...
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Low-Temperature Annealing of CdZnTeSe under Bias
původní článek
open access
vydavatelská verze
2022
,MDPI
,Sensors
,22
(1)
We performed a gradual low-temperature annealing up to 360 K on a CdZnTeSe radiation detector equipped with gold and indium electrodes under bias at both polarities. We observed significant changes in the detector's ...
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Projected changes in mean annual cycle of temperature and precipitation over the Czech Republic: Comparison of CMIP5 and CMIP6
původní článek
open access
vydavatelská verze
2022
,FRONTIERS MEDIA SA
,Frontiers in Earth Science [online]
,10
(6.10.2022)
The multi-model ensembles like CMIP5 or CMIP6 provide a tool to analyze structural uncertainty of climate simulations. Currently developed regional and local climate change scenarios for the Czech Republic assess the ...
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The Role of IL-6 in Cancer Cell Invasiveness and Metastasis — Overview and Therapeutic Opportunities
přehledový článek
open access
vydavatelská verze
2022
,Cells
,11
(22)
Interleukin 6 (IL-6) belongs to a broad class of cytokines involved in the regulation of various homeostatic and pathological processes. These activities range from regulating embryonic development, wound healing and ageing, ...
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PD1+CD8+ Cells Are an Independent Prognostic Marker in Patients with Head and Neck Cancer
původní článek
embargo
vydavatelská verze
2022
,Biomedicines
,10
(11)
Head and neck squamous cell carcinomas (HNSCCs) belong to a group of diverse tumors, which can be induced by infection with human papillomavirus (HPV) or tobacco and alcohol con sumption. The viral etiology of HNSCC relates ...
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Future changes in snowpack will impact seasonal runoff and low flows in Czechia
původní článek
open access
vydavatelská verze
2021
,Journal of Hydrology: Regional Studies [online]
,37
(October)
Study Region Central Europe, Czechia. Study Focus Mountains are referred to as "water towers" because they substantially affect the hydrology of downstream areas. However, snow storages will decrease in the future due to ...
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Electrophysiological and computational analysis of Ca(v)3.2 channel variants associated with familial trigeminal neuralgia
původní článek
embargo
vydavatelská verze
2022
,Molecular Brain
,15
(November)
Trigeminal neuralgia (TN) is a rare form of chronic neuropathic pain characterized by spontaneous or elicited paroxysms of electric shock-like or stabbing pain in a region of the face. While most cases occur in a sporadic ...
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Group of cancer immunotherapy and molecular epidemiology of virus infections
abstrakt v konferenčním sborníku
open access
vydavatelská verze
2022
,Praha
,Czech Chemical Society Symposium Series
,20
(6)
The group is composed of the team of Laboratory of Molecular and Tumor Virology (headed by Ruth Tachezy) and Laboratory of Immunotherapy (headed by Michal Šmahel). While the research of the team led by Ruth Tachezy focuses ...
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Discovery of new antiviral defense mechanisms
abstrakt v konferenčním sborníku
open access
vydavatelská verze
2022
,Praha
,Czech Chemical Society Symposium Series
,20
(3)
In this project, we will study mechanisms of hepatitis B virus escape from adaptive and innate immunity to discover novel antiviral therapeutic targets for the development of drugs to treat chronically infected patients
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Development of antimicrobial agents with activity against drug-resistant bacteria
abstrakt v časopisu
open access
vydavatelská verze
2022
,Czech Chemical Society Symposium Series
,20
(6)
Tuberculosis (TB) is a widespread infectious disease predominantly caused by Mycobacterium tuberculosis (M. tuberculosis). The discovery and widespread use of antimicrobials effective against TB starting in the middle of ...
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Phlebovirus Transmission by Sand Flies
abstrakt v konferenčním sborníku
open access
postprint
2022
,Praha
,Czech Chemical Society Symposium Series
,20
(6)
Arboviruses of the genus Phlebovirusare currently represented by 67 species found in Eurasia, Africa, and the Americas1. Although they have a great impact on human and animal health, information about their biology ...
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Transcription apparatus of the yeast virus-like elements is closely related to the poxviral transcription apparatus
abstrakt v konferenčním sborníku
open access
vydavatelská verze
2022
,Praha
,Czech Chemical Society Symposium Series
,20
(6)
We employed virus-like elements (VLEs) pGKL1,2 from Kluyveromyces lactisas a model to investigate the previously neglected transcriptome of the broader group of yeast cytoplasmic linear dsDNA VLEs. We found that RNA ...
