Zobrazují se záznamy 541-560 z 938

    • Effects of Lactiplantibacillus plantarum and Lacticaseibacillus paracasei supplementation on the faecal metabolome in children with coeliac disease autoimmunity: a randomised, double-blinded placebo-controlled clinical trial 

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      Jenickova, Eliska

      ;

      Andrén Aronsson, Carin

      ;

      Mascellani Bergo, Anna

      ;

      Cinek, Ondřej

      ;

      Havlik, Jaroslav

      ;

      Agardh, Daniel

      2023

      ,

      Frontiers in Nutrition

      ,

      10

      (July)

      INTRODUCTION: Coeliac disease is a lifelong immune-mediated enteropathy manifested as gluten intolerance in individuals carrying specific human leukocyte antigen (HLA) molecules. Other factors than genetics and gluten ...

    • An emerging Panton-Valentine leukocidin (PVL)-positive CC5-meticillin-resistant Staphylococcus aureus-IVc clone recovered from hospital and community settings over a 17-year period from 12 countries investigated by whole-genome sequencing 

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      Aloba, Bisola K

      ;

      Kinnevey, Peter M

      ;

      Monecke, Stefan

      ;

      Brennan, Gráinne I

      ;

      O'Connell, Brian

      ;

      Blomfeldt, Anita

      ;

      McManus, Brenda A

      ;

      Schneider-Brachert, Wulf

      ;

      Tkadlec, Jan

      ;

      Ehricht, Ralf

      ;

      Senok, Abiola

      ;

      Bartels, Mette Damkjær

      ;

      Coleman, David C

      2023

      ,

      Journal of Hospital Infection

      ,

      132

      (February)

      BACKGROUND: A novel Panton-Valentine leukocidin (PVL)-positive meticillin-resistant Staphylococcus aureus (MRSA) clonal complex (CC)5-MRSA-IVc ('Sri Lankan' clone) was recently described from Sri Lanka. Similar isolates ...

    • A creative destruction approach to replication: Implicit work and sex morality across cultures 

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      Tierney, Warren

      ;

      Hardy III., Jay

      ;

      Ebersole, Charles R.

      ;

      Viganola, Domenico

      ;

      Ropovik, Ivan

      2021

      ,

      Journal of Experimental Social Psychology

      ,

      93

      (1)

      How can we maximize what is learned from a replication study? In the creative destruction approach to replication, the original hypothesis is compared not only to the null hypothesis, but also to predictions derived from ...

    • NGS better discriminates true MRD positivity for the risk stratification of childhood ALL treated on MRD-based protocol 

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      Svatoň, Michael

      ;

      Skotnicová, Aneta

      ;

      Řezníčková, Leona

      ;

      Rennerová, Andrea

      ;

      Valová, Taťána

      ;

      Kotrova, Michaela

      ;

      van der Velden, Vincent H J

      ;

      Brüggemann, Monika

      ;

      Darzentas, Nikos

      ;

      Langerak, Anton W

      ;

      Zuna, Jan

      ;

      Starý, Jan

      ;

      Trka, Jan

      ;

      Froňková, Eva

      2023

      ,

      Blood

      ,

      141

      (5)

      We compared minimal residual disease (MRD) levels evaluated by routinely used real-time quantitative PCR (qPCR) patient-specific assays and by next generation sequencing (NGS) approach in 780 immunoglobulin/T-cell receptor ...

    • Changes in reproductive behavior associated with the perception and individual experiences of the COVID-19 pandemic 

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      Slabá, Jitka

      2023

      ,

      PLoS One

      ,

      18

      (7)

      This study evaluates the impacts of the COVID-19 pandemic on the reproductive behavior of men and women during the most restrictive period of the pandemic in Czechia. At the end of this period, data was collected for the ...

    • Mouse PML protein isoforms and their role in Mouse Polyomavirus infection 

      abstrakt v konferenčním sborníku

      open access

      preprint

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      Anderová, Karolína

      ;

      Ryabchenko, Boris

      ;

      Šroller, Vojtěch

      ;

      Horníková, Lenka

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2023

      ,

      Praha

      ,

      WBW 2023 Book of Abstracts

      Promyelocytic leukaemia nuclear bodies (PML NBs) are dynamic, spherical, membrane-less structures composed of the main scaffold PML protein and a variety of stable or transient partner proteins. Apart from many endogenous ...

    • Mouse Polyomavirus Affects Nuclear Lamina in the Late Phase of Infection 

      abstrakt v konferenčním sborníku

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      Bruštíková, Kateřina

      ;

      Forstová, Jitka

      ;

      Horníková, Lenka

      2023

      ,

      WBW 2023 Book of Abstracts

      One of the important components of nuclear cytoskeleton is nuclear lamina. It is composed of intermediate filaments V, A type lamins (lamin A/C) and B type lamins (lamin B1 and B2). Although nuclear lamina maintains the ...

    • Regulation of Phenolic Compound Production by Light Varying in Spectral Quality and Total Irradiance 

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      Pech, Radomír

      ;

      Volná, Adriana

      ;

      Hunt, Lena Macrie

      ;

      Bartas, Martin

      ;

      Červeň, Jiří

      ;

      Pečinka, Petr

      ;

      Špunda, Vladimír

      ;

      Nezval, Jakub

      2022

      ,

      International Journal of Molecular Sciences

      ,

      23

      (12)

      Photosynthetically active radiation (PAR) is an important environmental cue inducing the production of many secondary metabolites involved in plant oxidative stress avoidance and tolerance. To examine the complex role of ...

    • Antimycobacterial pyridine carboxamides: From design to in vivo activity 

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      Nawrot, Daria Elżbieta

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      Bouz, Ghada

      ;

      Janďourek, Ondřej

      ;

      Konečná, Klára

      ;

      Paterová, Pavla

      ;

      Bárta, Pavel

      ;

      Novák, Martin

      ;

      Kučera, Radim

      ;

      Zemanová, Júlia

      ;

      Forbak, Martin

      ;

      Korduláková, Jana

      ;

      Pavliš, Oto

      ;

      Kubíčková, Pavla

      ;

      Doležal, Martin

      ;

      Zitko, Jan

      2023

      ,

      European Journal of Medicinal Chemistry

      ,

      258

      (October)

      Tuberculosis is the number one killer of infectious diseases caused by a single microbe, namely Mycobacterium tuberculosis (Mtb). The success rate of curing this infection is decreasing due to emerging antimicrobial ...

    • Prevalence of Dual Diagnoses among Children and Adolescents with Mental Health Conditions 

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      Jandáč, Tomáš

      ;

      Šťastná, Lenka

      2023

      ,

      Children-Basel [online]

      ,

      10

      (2)

      Background: The World Health Organisation defines dual diagnosis as the co-occurrence in the same individual of a psychoactive substance use disorder and another psychiatric disorder. Children and adolescents with dual ...

    • Primary assessment of medicines for expected migrastatic potential with holographic incoherent quantitative phase imaging 

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      Šuráňová, Markéta

      ;

      Ďuriš, Miroslav

      ;

      Štenglová Netíková, Irena

      ;

      Brábek, Jan

      ;

      Horák, Tomáš

      ;

      Jůzová, Veronika

      ;

      Chmelík, Radim

      ;

      Veselý, Pavel

      2023

      ,

      Biomedical Optics Express

      ,

      14

      (6)

      Solid tumor metastases cause most cancer-related deaths. The prevention of their occurrence misses suitable anti-metastases medicines newly labeled as migrastatics. The first indication of migrastatics potential is based ...

    • Serum Metabolite Biomarkers for Pancreatic Tumors: Neuroendocrine and Pancreatic Ductal Adenocarcinomas-A Preliminary Study 

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      open access

      vydavatelská verze

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      Skubisz, Karolina

      ;

      Dąbkowski, Krzysztof

      ;

      Samborowska, Emilia

      ;

      Starzyńska, Teresa

      ;

      Deskur, Anna

      ;

      Ambrożkiewicz, Filip

      ;

      Karczmarski, Jakub

      ;

      Radkiewicz, Mariusz

      ;

      Kusnierz, Katarzyna

      ;

      Kos-Kudła, Beata

      ;

      Sulikowski, Tadeusz

      ;

      Cybula, Patrycja

      ;

      Paziewska, Agnieszka

      2023

      ,

      Cancers

      ,

      15

      (12)

      BACKGROUND: Pancreatic cancer is the most common pancreatic solid malignancy with an aggressive clinical course and low survival rate. There are a limited number of reliable prognostic biomarkers and a need to understand ...

    • DNA Repair Pathway in Ovarian Cancer Patients Treated with HIPEC 

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      Flasarova, Dominika

      ;

      Urban, Katerina

      ;

      Strouhal, Ondrej

      ;

      Klos, Dusan

      ;

      Lemstrova, Radmila

      ;

      Dvořák, Pavel

      ;

      Souček, Pavel

      ;

      Mohelnikova-Duchonova, Beatrice

      2023

      ,

      International Journal of Molecular Sciences

      ,

      24

      (10)

      DNA repair pathways are essential for maintaining genome stability, and understanding the regulation of these mechanisms may help in the design of new strategies for treatments, the prevention of platinum-based chemoresistance, ...

    • Mediálny obraz hromadného posadnutia v Morzine v rakúskej tlači 

      Interpretation of the mass possession in Morzine by contemporary Austrian press

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      Ondreička, Peter

      2022

      ,

      Theatrum historiae

      ,

      17

      (30)

      Štúdia sa zameriava na hromadné posadnutie v Morzine v polovici 19. storočia. Hlavným cieľom je analyzovať reflexiu posadnutia dobovými médiami. V novinových článkoch sme identifikovali 6 diskurzov. V prvom môžeme vidieť ...

    • 2,6-Disubstituted 7-(naphthalen-2-ylmethyl)-7H-purines as a new class of potent antitubercular agents inhibiting DprE1 

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      Finger, Vladimír

      ;

      Kučera, Tomáš

      ;

      Kafková, Radka

      ;

      Múčková, Ľubica

      ;

      Doležal, Rafael

      ;

      Kubeš, Jan

      ;

      Novák, Martin

      ;

      Prchal, Lukáš

      ;

      Lakatos, Levente

      ;

      Andrš, Martin

      ;

      Hympánová, Michaela

      ;

      Marek, Jan

      ;

      Kufa, Martin

      ;

      Spiwok, Vojtěch

      ;

      Soukup, Ondřej

      ;

      Mezeiová, Eva

      ;

      Janoušek, Jiří

      ;

      Nevosadová, Lenka

      ;

      Benková, Markéta

      ;

      Kitson, Russell R. A.

      ;

      Krátký, Martin

      ;

      Bősze, Szilvia

      ;

      Mikušová, Katarína

      ;

      Hartkoorn, Ruben

      ;

      Roh, Jaroslav

      ;

      Korábečný, Jan

      2023

      ,

      European Journal of Medicinal Chemistry

      ,

      258

      (October)

      Phenotypic screening of an in-house library of small molecule purine derivatives against Mycobacterium tuberculosis (Mtb) led to the identification of 2-morpholino-7-(naphthalen-2-ylmethyl)-1,7-dihydro-6H-purin-6-one 10 ...

    • Contagious Defaults in Interbank Networks 

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      Elminejad Anjileh, Mohammad Ali

      2022

      ,

      Finance a úvěr

      ,

      72

      (2)

      This paper investigates systemic risk and contagion processes in an interbank network using network science methods. The interbank network is studied to understand the contagion process within a network considering differences ...

    • You like it, you learn it: affectivity and learning in competitive social role play gaming 

      původní článek

      omezený přístup

      vydavatelská verze

      Ikona Jiná licence

      Brom, Cyril

      ;

      Šisler, Vít

      ;

      Slussareff, Michaela

      ;

      Selmbacherová, Tereza

      ;

      Hlávka, Zdeněk

      2016

      ,

      International Journal of Computer-Supported Collaborative Learning

      ,

      11

      (3)

      Despite the alleged ability of digital game-based learning (DGBL) to foster positive affect and in turn improve learning, the link between affectivity and learning has not been sufficiently investigated in this field. ...

    • Editorial: Mobile genetic elements as dissemination drivers of multidrug-resistant Gram-negative bacteria 

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      Nodari, Carolina Silva

      ;

      Opazo-Capurro, Andres

      ;

      Castillo-Ramirez, Santiago

      ;

      Mattioni Marchetti, Vittoria

      2023

      ,

      Frontiers in Cellular and Infection Microbiology

      ,

      13

      (March)

      Mobile genetic elements as dissemination drivers of multidrug-resistant Gram-negative bacteria - no abstract available

    • Gut Microbiome Diversity of Porcine Peritonitis Model of Sepsis 

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      Chalupová, Miroslava

      ;

      Horák, Jan

      ;

      Kramná, Lenka

      ;

      Nalos, Lukáš

      ;

      Štengl, Milan

      ;

      Chudějová, Kateřina

      ;

      Kraftová, Lucie

      ;

      Cinek, Ondřej

      ;

      Klein, Pavel

      ;

      Matějovič, Martin

      ;

      Hrabák, Jaroslav

      2022

      ,

      Czech Chemical Society Symposium Series

      ,

      20

      (6)

      Animal models are essential in understanding of the mechanisms of sepsis moreover the development and the assessment of emerging therapies. In clinically relevant porcine model, however, a significant ...

    • Survival in Lung Cancer in the Nordic Countries Through A Half Century 

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      Tichánek, Filip

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      Forsti, Asta

      ;

      Hemminki, Otto

      ;

      Hemminki, Akseli

      ;

      Hemminki, Kari Jussi

      2023

      ,

      Clinical Epidemiology

      ,

      15

      (May)

      Objective: Lung cancer is often diagnosed at an advanced stage and survival has been poor, although long-term studies have been rare. We analyzed data on survival in lung cancer from Denmark, Finland, Norway, and Sweden ...