A new type of hydrophilic, biocompatible, and biodegradable polypeptide nanogel depots loaded with the natural serine protease inhibitor α(1)-antitrypsin (AAT) was applied for the inhibition of the inflammatory mediator ...
The ocular surface is in constant interaction with the environment and with numerous pathogens. Therefore, complex mechanisms such as a stable tear film and local immune defense mechanisms are required to protect the eye. ...
Oxysterols, oxidized derivatives of cholesterol, act in breast cancer (BC) as selective estrogen receptor modulators and affect cholesterol homeostasis, drug transport, nuclear and cell receptors, and other signaling ...
Exercise order is one of the significant factors modulating training effects. Therefore, the aim of this study was to compare the effectiveness of an 8-week complex (CPX) training program utilizing intra-CPX active recovery ...
Radioactive (radon) groundwaters are highly valued among mineral waters for their healing effects. Between 2005 and 2015, a large exploratory event for prospecting and documenting radon water springs took place in the ...
TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene expression. Dysregulation of their activity is associated with many serious pathogenic states such as oncological diseases. ...
Honey bees are globally important pollinators threatened by many different pathogens, including viruses. We investigated the virome of honey bees collected at the end of the beekeeping season (August/September) in Czechia, ...
Biosocial impact of facial dominance and sex-typicality is well-evidenced in various human groups. It remains unclear, though, whether perceived sex-typicality and dominance can be consistently predicted from sexually ...
Layered zeolites, especially MWW, have been used to synthesize pillared micro/mesoporous hybrids with the goal to enhance catalytic activity towards larger molecules. The critical preparation step is expansion of the ...
BK polyomavirus (BKPyV) often reactivates after kidney transplantation, causing BKPyV-associated nephropathy (BKPyVAN) in 1-10% of cases with a potential detrimental effect on allograft survival. Kidney transplant recipients ...