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Poslední příspěvky
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Hölderlinovy básně z prvního období ve věži
Hölderlin´s Poems form the first Period in the Tower
původní článek
open access
vydavatelská verze
2024
,Svět literatury
,34
(70)
České résumé: Článek je věnován básním německého básníka Friedricha Hölderlina, které psal po své propuštění z kliniky, tj. přibližně v letech 1807 až 1820. Autor se pokouší dokázat, že texty z této doby, které řadí do ...
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ADAR1 knockout leads to global deregulation of translation and to translational shutdown upon IFN-α/β treatment in human Huh7.5 hepatocytes
abstrakt v elektronické podobě
open access
vydavatelská verze
2024
,Abstracts of papers presented at the 2024 meeting on TRANSLATIONAL CONTROL
In recent years, numerous evidence has been accumulated about the extent of A-to-I editing in human RNAs and the key role ADAR1 plays in the cellular editing machinery. It has been shown that A-to-I editing occurrence and ...
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Cannabidiol disrupts tryptophan metabolism in the human term placenta
původní článek
open access
vydavatelská verze
2024
,Toxicology
,505
(153813)
The increasing use of cannabis during pregnancy raises concerns about its impact on fetal development. While cannabidiol (CBD) shows therapeutic promise, its effects during pregnancy remain uncertain. We investigated CBD's ...
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Metformin inhibits OCT3-mediated serotonin transport in the placenta
původní článek
open access
vydavatelská verze
2024
,Biomedicine & Pharmacotherapy
,179
(117399)
Proper fetal development requires tight regulation of serotonin concentrations within the fetoplacental unit. This homeostasis is partly maintained by the placental transporter OCT3/SLC22A3, which takes up serotonin from ...
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Developmental expression of catecholamine system in the human placenta and rat fetoplacental unit
původní článek
open access
vydavatelská verze
2024
,Scientific Reports
,14
(1)
Catecholamines norepinephrine and dopamine have been implicated in numerous physiological processes within the central nervous system. Emerging evidence has highlighted the importance of tightly regulated monoamine levels ...
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Understanding the effect of term limits on voter turnout: Evidence from a quasi-experiment in Costa Rica based on a registered report
původní článek
open access
vydavatelská verze
2024
,Research & Politics
,11
(3)
Imposing term limits on elected officials is expected to increase turnout due to enhanced competition by one theoretical perspective, while another predicts depressed turnout as a result of clientelist turnout buying. These ...
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Akutní infarkt myokardu a preexistující levostranné chlopenní vady
přednáška
open access
vydavatelská verze
2024
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Survival in Thyroid Cancer in Sweden From 1999 To 2018
původní článek
open access
vydavatelská verze
2024
,Clinical Epidemiology
,16
(2 October 2024)
INTRODUCTION: Thyroid cancer (TC) is diagnosed in several histological types which differ in their clinical characteristics and survival. We aim to describe how they influence TC survival in Sweden. METHODS: Cancer data ...
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Complex Relationships between Diagnostics and Survival in Chronic Lymphocytic Leukemia in Denmark, Finland, Norway, and Sweden
původní článek
open access
vydavatelská verze
2024
,Cancers
,16
(18)
BACKGROUND: Chronic lymphocytic leukemia (CLL) is a common hematological malignancy with highly variable clinical presentation. Many patients never require any treatment but for the others, chemotherapy, immunochemotherapy, ...
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A novel F type plasmid encoding mcr-10 in a clinical Enterobacter ludwigii strain from a tertiary hospital in Czech Republic
původní článek
open access
vydavatelská verze
2024
,Journal of Global Antimicrobial Resistance
,37
(June)
Objective: Here we describe a novel IncFIA plasmid harboring mcr-10 gene in a clinical Enterobacter ludwigii strain isolated at the University Hospital in Pilsen in the Czech Republic.Methods: The strain was subjected to ...
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Percutaneous transthoracic needle biopsy of lung lesions is a safe method associated with a very low risk of pleural recurrence
původní článek
open access
vydavatelská verze
2024
,Biomedical Papers
AIM: Percutaneous transthoracic needle biopsy (PTNB), an alternative to bronchoscopic confirmation of lung lesions, is today being associated with a risk of pneumothorax and hemorrhage. Further, there are no data on the ...
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Emergence of Escherichia coli ST131 carrying carbapenemase genes, European Union/European Economic Area, August 2012 to May 2024
původní článek
open access
postprint
2024
,Eurosurveillance
,29
(47)
Analysis of 594 isolates of Escherichia coli sequence type (ST)131 and its single locus variants carrying carbapenemase genes from 17 European Union/European Economic Area countries revealed acquisition of 18 carbapenemase ...
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Geldanamycin, a Naturally Occurring Inhibitor of Hsp90 and a Lead Compound for Medicinal Chemistry
přehledový článek
open access
vydavatelská verze
2024
,Journal of Medicinal Chemistry
,67
(20)
Geldanamycin remains a driver in the medicinal chemistry of heat shock protein 90 (Hsp90) inhibition, even half a century after its original isolation from nature. This Perspective focuses on the properties of the benzoquinone ...
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Tetralogy of Fallot: Physiological and morphological changes in conditional Jagged1 mutant mice
poster
open access
vydavatelská verze
2024
The Notch signaling pathway is an evolutionarily conserved intercellular signaling mechanism essential for embryonic development in mammals. Mutations in the human Jagged1 (Jag1) gene, which encodes a ligand for the Notch, ...
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The Difference between Total and Inexact Differential Using 3D Printing Technology and LEGO© Bricks: Application on the First Law of Thermodynamics
abstrakt v konferenčním sborníku
open access
postprint
2022
,Wroclaw
,Institute of Experimental Physics, University of Wrocław
,25th International Workshop on Multimedia in Physics Teaching and Learning - Bookof Abstracts
The poster presents two educational kits created with the help of 3D printing technology. Both kits are used as a part of the course of advanced thermodynamics aimed specially at future high school teachers. The kits deal ...
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Neural processing of speech sounds at premature and term birth: ERPs and MMR between 32 and 42 weeks of gestation
původní článek
open access
vydavatelská verze
2024
,Developmental Cognitive Neuroscience
,70
(DEC)
Prenatal listening experience reportedly modulates how humans process speech at birth, but little is known about how speech perception develops throughout the perinatal period. The present experiment assessed the neural ...
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Two pathogens in one vector
abstrakt v elektronické podobě
open access
postprint
2024
,Praha
,Česká společnost chemická
,Czech Chemical Society Symposium Series
Sand flies (Diptera: Phlebotominae) are tiny hematophagous insects that play a critical role in the circulation of various pathogens. To explore pathogens interaction within their shared vector, Phlebotomus tobbi, we ...
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Modulation of Leishmania infection in sand flies by insect ́s midgut microbiota
abstrakt v elektronické podobě
open access
postprint
2024
,Praha
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,22
(6)
The midgut microbiota of insect vectors has been recognized as a critical factor influencing the transmission dynamics of vector-borne pathogens1-3. Sand flies (Diptera: Phlebotominae), tiny blood ...
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The out-of-hospital cardiac arrest in patients with acute myocardial infarction and pre-existing aortic stenosis
poster
open access
vydavatelská verze
2024
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Prognosis of cardiogenic shock following acute myocardial infarction
přednáška
open access
vydavatelská verze
2023
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