Fakulty
Procházet dle
Kolekce v této komunitě
Poslední příspěvky
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Molecular Screening in Anaplastic Lymphoma Kinase–Positive Anaplastic Large Cell Lymphoma: Anaplastic Lymphoma Kinase Analysis, Next-Generation Sequencing Fusion Gene Detection, and T-Cell Receptor Immunoprofiling
původní článek
open access
vydavatelská verze
2024
,Modern Pathology
,37
(3)
Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma (ALK+ ALCL) originates from the T-lineage and is marked by rearrangements of the ALK gene. Over ten fusion partners with the ALK gene are known, with the ...
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STING regulation in polyomavirus infections
abstrakt v elektronické podobě
open access
vydavatelská verze
2024
,Itálie
,Gianni Cinello, Lithostampa SrL, Udine
,ICGEB DNA Tumour Virus Meeting
Stimulator of interferon genes (STING) is an indispensable component of cGAS-STING signalization pathway that plays a key role in the innate immune response to polyomavirus infection. Infection of cells by polyomaviruses ...
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Public history: praktiky, média, instituce
Public History: Practices, Media, Institutions
VŠ skriptum
open access
vydavatelská verze
2024
,Praha
,Univerzita Karlova, Filozofická Fakulta
Kniha Public history: praktiky, média, instituce vychází ze současných trendů na poli paměťových studií, public history a teorie historického vzdělávání, přičemž zdůrazňuje všudypřítomnost obrazů minulosti, význam mediálního ...
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Pediatric basilar invagination: Unveiling a rare complication of inflammatory bowel disease unclassified
kazuistika
open access
vydavatelská verze
2024
,PM and R
,E-PUB
This case report details the presentation of an 8-year-old boy with atlantoaxial rotatory dislocation (AARD) and basilar invagination (BI), an exceedingly rare complication of inflammatory bowel disease unclassified (IBDU). ...
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Aspartate-β-hydroxylase and hypoxia marker expression in head and neck carcinomas: implications for HPV-associated tumors
původní článek
embargo
vydavatelská verze
2024
,Infectious Agents and Cancer
,19
(1)
BACKGROUND: A proportion of head and neck carcinomas (HNSCCs) are induced by high-risk human papillomaviruses (HPVs) and are associated with better patient outcomes compared to patients with HNSCCs related to tobacco and ...
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O čem také přemýšlejí naši medici. Sborník studentských prací (2024)
Thoughts of medical students. Collection of written projects (2024)
sborník
open access
vydavatelská verze
2024
,Plzeň
,Psychiatrická klinika, Lékařská fakulta v Plzni Univerzity Karlovy
Výbor nejlepších esejí napsaných studenty Lékařské fakulty Univerzity Karlovy v Plzni pro předmět Lékařská psychologie a etika v akademickém roce 2023/2024.
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Příklad tvorby vážné digitální hry na základě zkušeností z kurzu „Design vážných her“ na letní škole v Tallinu
An example of designing a serious digital game based on experiences from Design of serious games summer school course in Tallin
jiný článek
open access
vydavatelská verze
2022
,Pedagogická orientace
,32
(2)
Letní škola v Tallinu probíhala od 11. do 29. 7. 2022 a nabídla studentům 22 kurzů nejrůznějšího zaměření. Kurz, jehož jsem byla účastníkem, s názvem "Design vážných her" probíhal od 18. do 22.7 a zúčastnilo se jej 14 lidí ...
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Expanding Observability via Human-Machine Cooperation
původní článek
embargo
postprint
2022
,Axiomathes
,32
(Suppl. 3)
We ask how to use machine learning to expand observability, which presently depends on human learning that informs conceivability. The issue is engaged by considering the question of correspondence between conceived ...
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Überwindung des Zwischenraumes: Ernst Weiß’ Erzählung Marengo im Literaturunterricht
Overcoming the gap: Ernst Weiß’ story Marengo in literature classes
původní článek
open access
vydavatelská verze
2023
,Schnittstelle Germanistik
,3
(2)
Das Ziel des vorliegenden Beitrags ist es, den Prager deutschen Autor Ernst Weiß kurz vorzustellen, und die Möglichkeiten für den Literaturunterricht zu skizzieren, die seine Erzählung Marengo bietet. Nachdem die Struktur ...
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Virological characteristics of the SARS-CoV-2 Omicron EG.5.1 variant
původní článek
open access
vydavatelská verze
2024
,Microbiology and immunology
,AHEAD OF PRINT
(First published: 04 July 2024)
In middle to late 2023, a sublineage of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron XBB, EG.5.1 (a progeny of XBB.1.9.2), is spreading rapidly around the world. We performed multiscale investigations, ...
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Czech Republic – ECEC Workforce Profile
kapitola v kolektivní monografii
open access
vydavatelská verze
2024
,Munich
,State Institute of Early Childhood Research and Media Literacy
,Early childhood workforce profiles across Europe: 33 country reports with key contextual data
The chapter provides comprehensive information on the types of professionals working in ECEC in the Czech Republic. The chapter focuses on the different types of positions in various ECEC settings in the Czech Republic. ...
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Emerging Role of Circulating Cell-Free RNA as a Non-Invasive Biomarker for Hepatocellular Carcinoma
původní článek
open access
vydavatelská verze
2024
,Critical Reviews in Oncology/Hematology
,200
(August)
Hepatocellular carcinoma (HCC) is a severe neoplastic disease associated with high morbidity and mortality rates. HCC is often detected at advanced stages leading to ineffective curative treatments. Recently, liquid biopsy ...
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Major improvement in thyroid cancer survival of elderly patients in the Nordic countries
původní článek
open access
vydavatelská verze
2024
,European Journal of Endocrinology
,190
(3)
Objectives We describe age-specific survival in thyroid cancer (TC) from Denmark, Finland, Norway, and Sweden over a 50-year period.Design Population-based survival study.Methods Relative 5-year survival data were obtained ...
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Concomitant antihypertensive medication and outcome of patients with metastatic castration-resistant prostate cancer receiving enzalutamide or abiraterone acetate
původní článek
open access
vydavatelská verze
2024
,Cancer Medicine
,13
(1)
BACKGROUND: The introduction of novel hormonal therapies represented by enzalutamide (ENZ) and abiraterone acetate (ABI) has reached a great progress in the treatment of metastatic castration-resistant prostate cancer ...
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Frentizole derivatives with mTOR inhibiting and senomorphic properties
původní článek
open access
vydavatelská verze
2023
,Biomedicine & Pharmacotherapy
,167
(November)
Frentizole is immunosuppressive drug with low acute toxicity and lifespan-prolonging effect. Recently, frentizole's potential to disrupt toxic amyloid β (Aβ) - Aβ-binding alcohol dehydrogenase (ABAD) interaction in ...
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Detection of prions in matching post-mortem skin and cerebrospinal fluid samples using second-generation real-time quaking-induced conversion assay
původní článek
open access
vydavatelská verze
2024
,Scientific Reports
,14
(March)
Real-time quaking-induced conversion assay (RT-QuIC) exploits templating activity of pathogenic prion protein for ultrasensitive detection of prions. We have utilized second generation RT-QuIC assay to analyze matching ...
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Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists
původní článek
open access
vydavatelská verze
2024
,Biomedicine & Pharmacotherapy
,176
(July)
Therapeutic options for Alzheimer's disease are limited. Dual compounds targeting two pathways concurrently may enable enhanced effect. The study focuses on tacrine derivatives inhibiting acetylcholinesterase (AChE) and ...
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How to invasively assess left ventricular function and its efficiency of work
přehledový článek
open access
vydavatelská verze
2024
,Cor et Vasa
,66
(1)
Effective performance of the left ventricle requires the maintenance of a cardiac output as demanded by the systemic circulation without a high hemodynamic cost or pressure and without a high metabolic cost or oxygen demand ...
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The role of adipogenic capacity and dysfunctional subcutaneous adipose tissue in the inheritance of type 2 diabetes mellitus: cross-sectional study
původní článek
open access
vydavatelská verze
2024
,Obesity
,32
(3)
OBJECTIVE: This study tested the hypothesis that limited subcutaneous adipose tissue (SAT) expansion represents a primary predisposition to the development of type 2 diabetes mellitus (T2DM), independent of obesity, and ...
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Utilization of healthcare services in acute myocardial infarction and the risk of out-of-hospital cardiac death
letter to the editors
open access
vydavatelská verze
2024
,Panminerva Medica
,66
(1)
COVID-19 represented a significant challenge to cardiovascular (cV) medicine research, treatment, prevention, and, to a considerable extent, case management. The global pandemic viral infection increased the risk of ...
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