Fakulty
Procházet dle
Kolekce v této komunitě
Poslední příspěvky
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Proměna školy a vzdělávání
Transformation of Schools and Education
editorial
omezený přístup
aktualizovaná vydavatelská verze
2026
,Univerzita Karlova v Praze, Pedagogická fakulta
,Gramotnost, pregramotnost a vzdělávání
,10
(1)
Číslo časopisu se zaměřuje na aktuální otázky podpory vzdělávání napříč všemi stupni školského systému. Příspěvky reflektují změny v oblasti odkladů školní docházky z pohledu pracovníků školských poradenských zařízení i ...
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SOCIAL PRESCRIBING - preskripce nad rámec farmakoterapie: možnosti a příležitosti pro péči o starší populaci v ČR
Beyond medications: social prescribing for older adults
původní článek
open access
vydavatelská verze
2025
,Česká lékařská společnost Jana Evangelisty Purkyně
,Praktický lékař
,105
(2)
Úvod: Současný demografický vývoj zvyšuje potřebu hledání efektivních způsobů podpory starší populace, zejména v oblasti duševního zdraví, životní pohody a soběstačnosti. V ordinacích praktických lékařů se stále častěji ...
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Cancer invasion plasticity during the metastatic cascade: strategies to survive and thrive
přehledový článek
open access
vydavatelská verze
2026
,Elsevier Science
,Cancer Letters
,645
(1 May 2026)
The metastatic process is largely inefficient, yet its outcome - the dissemination of cancer cells from the primary tumor to distant sites and the formation of metastases - remains the leading cause of cancer-related death. ...
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Implementation and First Results of the Czech Nationwide Prostate Cancer Screening Pilot Program
původní článek
open access
vydavatelská verze
2026
,Elsevier B.V.
,European Urology Open Science
,91
(September)
Background: In 2022, the European Union recommended piloting organized prostate cancer screening. Subsequently, the Czech Republic launched a nationwide pilot program fully reimbursed by public health insurance in January ...
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Pyrazinamide-derived 1,2,3-triazoles: Antimicrobial evaluation, selective antimycobacterial activity and mechanism of action insights
původní článek
open access
vydavatelská verze
2026
,Elsevier
,European Journal of Medicinal Chemistry
,317
(5 November 2026)
A series of pyrazinamide-derived 1,2,3-triazoles featuring systematic chlorination of the pyrazine ring and diverse aryl substituents was synthesized and evaluated for antimycobacterial activity. Biological activity screening ...
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Negative interactions between Toscana virus and Leishmania infantum limit coinfection in sand flies
původní článek
open access
vydavatelská verze
2026
,BioMed Central
,Parasites & Vectors
,19
(1)
Background: Phlebotomine sand flies transmit a wide range of human and veterinary pathogens, including Leishmania spp. and Toscana virus (TOSV). Both pathogens co-circulate extensively in the Mediterranean basin and may ...
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Clinicopathological, Molecular, and DNA Methylation Analysis of Ossifying Fibromyxoid Tumors Delineates the ZC3H7B::BCOR Subset as a Distinct Entity
původní článek
open access
vydavatelská verze
2026
,Nature Publishing Group
,Modern Pathology
,39
(8)
Ossifying fibromyxoid tumor (OFMT) is a rare mesenchymal neoplasm of uncertain lineage of differentiation driven by a broad spectrum of gene fusions. It manifests primarily in soft tissues of the extremities. In this study, ...
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Molecular Mechanisms of Acanthamoeba castellanii Response to Different Sources of Oxidative Stress
původní článek
open access
vydavatelská verze
2025
,American Chemical Society
,Journal of Proteome Research
,24
(2)
Oxidative stress is a biological principle affecting all life on Earth and is also an important factor in the pathogen-host relationship. The pathogenic free-living amoeba Acanthamoeba castellanii has several pathways to ...
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Recent survival trends in the most fatal cancers in the Nordic countries: gains in some but not in all
původní článek
open access
vydavatelská verze
2026
,Acta Oncologica
,Acta Oncologica
,65
(29 June)
Background Global survival studies distinguish a group of solid cancers with especially poor survival, which in the Nordic countries are cancers of the hypopharynx, esophagus, stomach, liver, gallbladder, pancreas, lung ...
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High-risk lineages shape the resistome and virulome of multidrug-resistant Pseudomonas aeruginosa
původní článek
open access
vydavatelská verze
2026
,Frontiers Media SA
,Frontiers in Cellular and Infection Microbiology
,16
(June)
Multidrug-resistant (MDR) and extensively drug-resistant (XDR) Pseudomonas aeruginosa strains remain a major threat in clinical settings, yet no contemporary genomic data are available from the Olomouc region, Czech Republic. ...
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Exploring the full spectrum of reproductive experiences
původní článek
omezený přístup
vydavatelská verze
2026
,University of Bamberg Press
,Journal of Family Research
,38
(January 13)
Objective: The study examines changes across cohorts in terms of the timing and frequency of the full spectrum of reproductive events and explores whether these reproductive trajectories reflect broader trends towards the ...
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Analysis of triggering factors behind the October 2023 South Lhonak GLOF event in the Sikkim Himalaya using multiple remote sensing data
původní článek
open access
vydavatelská verze
2026
,Taylor
,Geomatics, Natural Hazards & Risk
,17
(1)
A catastrophic Glacial Lake Outburst Flood (GLOF) occurred from the South Lhonak Glacial Lake (SLGL) in the Sikkim Himalaya between October 3 and 4, 2023, highlighting the urgent need to understand its triggering mechanisms. ...
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Preventing Radicalisation, or Forcing Ideological Consent? Crises, Uncertainty Reduction and Collective Identity Negotiation in Collaborative Communities of Online Third Spaces
původní článek
open access
vydavatelská verze
2026
,SAGE Publications Ltd
,Social media + Society
,12
(2)
With regard to the recent accumulation of crisis events in Europe, scholars stress the potential of online spaces to reduce people's uncertainty through collective identity formation, providing their members with ...
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PRPF8-associated retinitis pigmentosa variant induces human neural retina-autonomous photoreceptor defects
původní článek
open access
vydavatelská verze
2026
,Springer Nature
,Scientific Reports
,16
(1)
Retinitis pigmentosa (RP) is an inherited retinal disorder characterized by the progressive loss of photoreceptors that currently lacks effective treatment. Here, we investigated the effects of the PRPF8-Y2334N variant on ...
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Does finance change the taste for redistribution?
původní článek
open access
vydavatelská verze
2026
,Elsevier Science
,European Journal of Political Economy
,94
(August 2026)
This paper investigates whether financial development is associated with people's preferences for redistribution. Although a large literature examines the effects of finance on growth and inequality, much less is known ...
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Mechanistic modeling of recessive disease through allelic integration of variant effects
původní článek
open access
vydavatelská verze
2026
,Elsevier
,Cell Systems
,17
(6)
Interpreting variants in recessive diseases is difficult because clinical severity depends on the combined function of both alleles. Deep mutational scanning (DMS) experiments can provide functional measurements at scale, ...
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A missense mutation in the SAA1 protein causing hereditary amyloid A amyloidosis
kazuistika
open access
vydavatelská verze
2026
,Elsevier
,Kidney International
,110
(1)
In summary, guided by the patient's clinical course and diagnostic challenges, we report, for the first time, a family with autosomal dominant hereditary AA amyloidosis caused by a heterozygous SAA1 missense mutation, ...
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Updated ENIGMA recommendations for reporting germline variants in cancer susceptibility genes and their translation into twenty languages
původní článek
open access
vydavatelská verze
2026
,BMJ Pub. Group
,Journal of Medical Genetics
,online AoP
(14 May 2026)
Genetic testing for cancer susceptibility underpins precision cancer prevention and care. Gaps in the healthcare providers' genetic literacy and an ambiguous lexicon for variant description may hinder proper delivery ...
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Genotype-phenotype characteristics and disease progression of FAN1-related karyomegalic tubulointerstitial nephropathy
původní článek
open access
vydavatelská verze
2026
,Elsevier
,Kidney International
,109
(4)
Introduction: Biallelic variants in Fanconi Anemia-associated Nuclease 1 (FAN1) cause karyomegalic tubulointerstitial nephropathy (KIN), a condition poorly characterized in terms of kidney survival, patient survival, and ...
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Clinicopathologic features of KRAS G12C-mutated non-small cell lung carcinomas:insights from 279 retrospective cases
původní článek
open access
vydavatelská verze
2026
,Springer
,Virchows Archiv
,489
(1)
KRAS G12C-mutated non-small cell lung carcinoma (NSCLC), caused by a glycine-to-cysteine substitution at codon 12, is associated with poor prognosis and is now targetable with specific inhibitors. We retrospectively analyzed ...

















