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Kolekce v této komunitě
Poslední příspěvky
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Mouse PML protein isoforms and their role in innate antiviral immunity
abstrakt v elektronické podobě
open access
postprint
2024
Promyelocytic leukaemia nuclear bodies (PML NBs) are dynamic, multiprotein, membrane-less structures composed of the main scaffold PML protein and various stable or transient partner proteins. Beyond their diverse endogenous ...
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ASPH inhibition reveals differential gene expression patterns in HPV-positive and HPV-negative cell lines
abstrakt v elektronické podobě
open access
preprint
2024
,Boston
Cancer is associated with alterations in key cellular pathways, including the aspartate β-hydroxylase (ASPH) pathway. ASPH is an oncogene upregulated in various carcinomas, playing a vital role in tumor progression and ...
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The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization
původní článek
open access
vydavatelská verze
2024
,PLoS Genetics
,20
(12)
The RNA content is crucial for the formation of nuclear compartments, such as nuclear speckles and nucleoli. Phosphatidylinositol 4,5-bisphosphate (PIP2) is found in nuclear speckles, nucleoli, and nuclear lipid islets and ...
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The long-term impact of biogenic volatile organic compound emissions on urban ozone patterns over central Europe: contributions from urban and rural vegetation
původní článek
open access
vydavatelská verze
2024
,Atmospheric Chemistry and Physics
,24
(10. 12. 2024)
The impact of biogenic emissions of hydrocarbons from vegetation on ozone, as well as on overall oxidative capacity of air, is analyzed for central European cities for a present-day period using a chemistry transport model. ...
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Investigating antibacterial and anti-inflammatory properties of synthetic curcuminoids
původní článek
open access
vydavatelská verze
2024
,Frontiers in Medicine
,11
(October)
The concept of intratumoral microbiota is gaining attention in current research. Tumor-associated microbiota can activate oncogenic signaling pathways such as NF-kappa B, thereby promoting tumor development and progression. ...
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The perinucleolar compartment and the oncogenic super-enhancers are part of the same phase-separated structure filled with phosphatidylinositol 4,5bisphosphate and long noncoding RNA HANR
původní článek
open access
vydavatelská verze
2024
,Advances in Biological Regulation
,AHEAD OF PRINT
(Available online 30 November 2024)
The liquid-liquid phase separation in the cell nucleus regulates various processes such as gene regulation and transcription control, chromatin organization, and DNA repair. A plethora of proteins and RNAs contribute to ...
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HPV Infection: Present and Future of Diagnostic and Prognostic Surveys
abstrakt v elektronické podobě
open access
postprint
2024
High-risk types of Human Papillomavirus (HPV) are closely associated with various human malignancies. The ability to detect precancerous stages early significantly impacts patient outcomes, yet challenges remain in the ...
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Post-COVID health policy responses to healthcare workforce capacities: a comparative analysis of health system resilience in six European countries
původní článek
open access
vydavatelská verze
2024
,Health Policy
,139
(January)
A cross countries in Europe, health policy is seeking to adapt to the post-pandemic 'permacrisis', where high demands on the healthcare workforce and shortages continue and combine with climate change, and war. The success ...
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Expert, experts et expertise pendant la crise de la COVID-19 – le cas tchèque
Experts, experts and expertise during the COVID-19 crisis - the Czech case
kapitola v kolektivní monografii
open access
vydavatelská verze
2024
,Stockholm
,Stockholm University Press
,Comparing the place of experts during the first waves of the COVID-19 pandemic
La crise de la COVID-19 a mis en lumière une catégorie d'experts déja bien connue en République tchèque, mais longtemps négligée et sous-financée : les épidémiologistes. Face a des défis que personne n'aurait pu prévoir, ...
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Československá sociologická společnost při ČSAV v zrcadle svých Zpráv (1964–69)
The Czechoslovak Sociological Society of the Czechoslovak Academy of Sciences Reflected by its Periodical Zprávy (1964–69)
původní článek
open access
vydavatelská verze
2024
,Lidé města / Urban People
,26
(3)
Autor analyzuje interní bullerin/časopis Československé sociologické společnosti, vycházející v letech 1965-69, a ukazuje, že ačkoli periodikum bylo velmi otevřené, tato otevřenost měla své limity, stejně jako nebylo plně ...
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Lipid and brain volumetric measures in multiple sclerosis patients: findings from a large observational study
původní článek
open access
vydavatelská verze
2024
,Acta Neurologica Belgica
,124
(6)
Objectives This study aimed to investigate relationships between cholesterol profile, brain volumetric MRI, and clinical measures in a large observational cohort of multiple sclerosis (MS) patients. Materials and methods ...
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Tidal Heating in a Subsurface Magma Ocean on Io Revisited
původní článek
open access
vydavatelská verze
2024
,Geophysical Research Letters
,51
(10)
We investigate the tidal dissipation in Io's hypothetical fluid magma ocean using a new approach based on the solution of the 3D Navier-Stokes equations. Our results indicate that the presence of a shallow magma ocean on ...
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The Linked Complexity of Coseismic and Postseismic Faulting Revealed by Seismo‐Geodetic Dynamic Inversion of the 2004 Parkfield Earthquake
původní článek
open access
vydavatelská verze
2024
,Journal of Geophysical Research: Solid Earth
,2024
(November)
Several regularly recurring moderate-size earthquakes motivated dense instrumentation of theParkfield section of the San Andreas fault (SAF), providing an invaluable near-fault observatory. We present aseismo-geodetic ...
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Identification of processes in Cu-ore heap leaching using Cu isotopes and leachate chemistry at Tschudi mine, northern Namibia
původní článek
open access
vydavatelská verze
2024
,Hydrometallurgy
,228
(October)
Copper isotopic fractionation (in δ(65)Cu) and leachate characterization were studied in the context of heap leaching at the Tschudi copper mine in northern Namibia. The leached solution is of Mg-SO4 type with high Al and ...
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Contribution of chemical toxicity to the overall toxicity of microplastic particles: A review
přehledový článek
open access
vydavatelská verze
2024
,Science of the Total Environment
,957
(December)
Nanoplastics and microplastics are of growing research interest due to their persistence in the environment and potential harm to organisms through physical damage, such as abrasions or blockages, and chemical harm from ...
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Thallium in Technosols from Allchar (North Macedonia): Isotopic and speciation insights
původní článek
open access
vydavatelská verze
2024
,Environmental Pollution
,357
(September)
Allchar (North Macedonia) mining area is known for anomalous background Tl concentrations. In this study, we combine accurate detection of Tl stable isotope ratios with data on mineralogy/speciation and chemical extraction ...
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Metal(loid)s in urban soil from historical municipal solid waste landfill: Geochemistry, source apportionment, bioaccessibility testing and human health risks
původní článek
open access
vydavatelská verze
2024
,Chemosphere
,362
(August)
Landfills, especially those poorly managed, can negatively affect the environment and human beings through chemical contamination of soils and waters. This study investigates the soils of a historical municipal solid waste ...
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Integrating vMAGs and Amplicon Sequencing: Bridging Gaps in Illumina-Based Assembly of Novel Large Viruses from Honey Bee Viromes
poster
open access
vydavatelská verze
2024
The study of viromes has been revolutionized by advanced bioinformatics methodologies that enable the precise identification of novel viruses. However, assembling complete genomes of large viruses is still challenging. To ...
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Multiparametric analysis of the specific immune response against SARS-CoV-2
původní článek
open access
vydavatelská verze
2024
,Infectious Diseases
,56
(10)
Background: SARS-CoV-2, which causes COVID-19, has killed more than 7 million people worldwide. Understanding the development of postinfectious and postvaccination immune responses is necessary for effective treatment and ...
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Infekce lidským papilomavirem (HPV) a gravidita
Human papillomavirus (HPV) infection and pregnancy
původní článek
open access
vydavatelská verze
2024
,Epidemiologie, mikrobiologie, imunologie
,73
(1)
Lidský papilomavirus (HPV) je celosvětově nejběžnější sexuálně přenosnou virovou infekcí, která může vést ke vzniku benigních lézí nebo maligních nádorů. Prevalence HPV infekce je u těhotných žen dvakrát vyšší než u ...
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