Zobrazují se záznamy 1-20 z 1761

    • Comparative analysis of telomere length in peripheral blood of breast cancer BRCA1 mutation carriers and non-carriers 

      původní článek

      open access

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      Uttarilli, Anusha

      ;

      Balounová, Kateřina

      ;

      Tomášová, Kristýna

      ;

      Hanak, Petr

      ;

      Šašková, Kateřina

      ;

      Vodička, Pavel

      ;

      Vodičková, Ludmila

      ;

      Hemminki, Kari Jussi

      ;

      Lubinski, Jan

      ;

      Kroupa, Michal

      2026

      ,

      Springer

      ,

      Discover Oncology

      ,

      17

      (1)

      INTRODUCTION: Breast cancer is the most prevalent malignancy among women worldwide. A significant portion of patients possess homologous recombination deficiency (HRD), often caused by BRCA1/2 mutations, which may sensitize ...

    • Ukrainian refugee children in Czech early childhood settings: why some families are more successful than others when integrating into a new environment 

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      open access

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      Loudová Stralczynská, Barbora

      ;

      Jelínková, Marie

      ;

      Oksana, Stupak

      2025

      ,

      Carfax

      ,

      Early Years

      ,

      Neuveden.

      (2025)

      This study applies the Community Cultural Wealth (CCW) framework to examine the experience of Ukrainian refugee families with young children adapting to early childhood education and care in the Czech Republic after 2022. ...

    • What to Do if a Plan Does Not Comply with an HTN Model? 

      příspěvek v recenzovaném konferenčním sborníku

      open access

      vydavatelská verze

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      Pantůčková, Kristýna

      ;

      Barták, Roman

      2025

      ,

      IOS Press

      ,

      ECAI 2025

      Plan verification deals with the problem of checking whether a given sequence of actions is a valid plan according to a planning domain model. If the action sequence is not a valid plan, the next question is where the ...

    • Hierarchical Plan Repair via Plan Recognition and Plan Correction 

      příspěvek v recenzovaném konferenčním sborníku

      open access

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      Pantůčková, Kristýna

      ;

      Barták, Roman

      2025

      ,

      LibraryPress@UF

      ,

      The International FLAIRS Conference Proceedings

      Hierarchical planning extends classical planning by introducing a hierarchy of tasks describing how tasks decompose into subtasks until primitive tasks -- actions -- forming a plan are obtained. Plan repair deals with plans ...

    • On Removing Left Recursion from Totally-ordered HTN Domain Models 

      příspěvek v recenzovaném konferenčním sborníku

      open access

      vydavatelská verze

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      Ondrčková, Simona

      ;

      Barták, Roman

      ;

      Kuboň, Vladislav

      2025

      ,

      USA

      ,

      FLAIRS

      ,

      Proceedings of the International Florida Artificial Intelligence Research Society Conference Flairs

      ,

      38

      Hierarchical planning is a knowledge-based approach to automated planning, where high-level (compound) tasks are decomposed into simpler tasks until primitive tasks - actions - forming the plan are obtained. Hierarchical ...

    • SHARED AND NON-SHARED MUTATIONS IN APC AND TP53 GENES IN PAIRED PRIMARY AND METASTATIC COLORECTAL CANCER FROM SYNCHRONOUS AND METACHRONOUS PATIENTS 

      původní článek

      open access

      preprint

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      Ambrożkiewicz, Filip

      ;

      Rajtmajerová, Marie

      ;

      Hlaváč, Viktor

      ;

      Trailin, Andriy

      ;

      Červenková, Lenka

      ;

      Brůha, Jan

      ;

      Šůsová, Simona

      ;

      Souček, Pavel

      ;

      Vodička, Pavel

      ;

      Vodičková, Ľudmila

      ;

      Kubeček, Ondřej

      ;

      Filip, Stanislav

      ;

      Mallela, Venkata Ramana

      ;

      Ye, Wenjing

      ;

      Liška, Václav

      ;

      Hemminki, Kari Jussi

      2026

      BackgroundMutational cascades in colorectal cancer (CRC) between the primary tumor (pCRC) and liver metasta-sis (LM) are poorly understood in individual patients. We focused on differences in specific APC and TP53 mutations ...

    • HRV-Based Recovery Across Menstrual Cycle Phases: Insights from a Pilot Study 

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      open access

      vydavatelská verze

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      Boďová Hybská, Tereza

      ;

      Jaklová Dytrtová, Jana

      ;

      Kroneislová, Markéta

      ;

      Baber, Farwa

      2026

      ,

      Betasciencepress Publishers

      ,

      Journal of Applied Bioanalysis

      ,

      11

      (9)

      This study investigated changes in HRV-based recovery metrics across menstrual cycle phases and explored the influence of physiological factors and physical activity using mySASY. Twenty healthy women were monitored across ...

    • Rain-on-snow events in mountainous catchments under climate change 

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      open access

      vydavatelská verze

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      Hotový, Ondřej

      ;

      Nedělčev, Ondřej

      ;

      Seibert, Jan

      ;

      Jeníček, Michal

      2025

      ,

      Copernicus Publ.

      ,

      Hydrology and Earth System Sciences

      ,

      29

      (17)

      The frequency and intensity of rain-on-snow (RoS) events are expected to change in response to climate variations due to changes in precipitation, increases in air temperature, and subsequent changes in the snow cover. In ...

    • The assessment of the recent mass balance anomaly of Adishi glacier in the Central Caucasus by satellite altimetry 

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      open access

      vydavatelská verze

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      Mehrishi, Pragya

      ;

      Kropáček, Jan

      2025

      ,

      John Wiley & Sons

      ,

      Earth Surface Processes and Landforms

      ,

      50

      (13)

      Glacier mass balance is a key indicator of climate change, with most glaciers worldwide exhibiting negative trends due to rising temperatures. However, Adishi Glacier in the Central Caucasus presents an anomaly published ...

    • Atmospheric warming drives shallow rock slope instability via irreversible joint opening 

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      Racek, Ondřej

      ;

      Morcioni, Andrea

      ;

      Blahůt, Jan

      ;

      Apuani, Tiziana

      ;

      Stepanek, Petr

      ;

      Scaringi, Gianvito

      2025

      ,

      Springer

      ,

      Landslides

      ,

      22

      (November 2025)

      Rock slopes are exposed to atmospheric temperature fluctuations, which affect the evolution of stresses and strains across various timescales. Climate change is modifying the thermal regime of rock masses, potentially ...

    • Analytical Formulas for the Structure of Perturbations in the Eady Model of Baroclinic Instability in the p-System 

      původní článek

      open access

      vydavatelská verze

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      Raidl, Aleš

      ;

      Bednář, Hynek

      ;

      Mikšovský, Jiří

      2025

      ,

      Stockholm University Press

      ,

      Tellus, Series A: Dynamic Meteorology and Oceanography

      ,

      77

      (1)

      Shortly after World War II, the first two models of baroclinic instability were independently published by Charney (1947) and Eady (1949). Both authors describe the origin and initial development of midlatitude weather ...

    • Physics-based broadband characterization of weak earthquakes 

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      open access

      vydavatelská verze

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      Gallovič, František

      ;

      Sgobba, Sara

      ;

      Valentová Krišková, Ľubica

      2025

      ,

      Nature Publishing Group

      ,

      Nature Communications

      ,

      16

      (1)

      Analyses of abundant small earthquakes have the potential to map the Earth's small-scale stress and frictional properties. However, standard seismological characterizations lack the resolution to capture the physical ...

    • Analysis of the complex role of trees in street canyons using a large-eddy simulation model 

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      open access

      vydavatelská verze

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      Řezníček, Hynek

      ;

      Geletič, Jan

      ;

      Belda, Michal

      ;

      Beneš, Luděk

      ;

      Bureš, Martin

      ;

      Eben, Kryštof

      ;

      Fuka, Vladimír

      ;

      Krč, Pavel

      ;

      Michálek, Petr

      ;

      Patino, William

      ;

      Radović, Jelena

      ;

      Suhring, Matthias

      ;

      Vlček, Ondřej

      ;

      Resler, Jaroslav

      2025

      ,

      Royal Meteorological Society

      ,

      Quarterly Journal of the Royal Meteorological Society

      ,

      151

      (769)

      While the positive effect of trees on thermal comfort is well-established, particularly in urban street canyons, their impact on air quality remains questionable, especially in the case of pollutants emitted by heavy traffic ...

    • Scenarios of Köppen-Trewartha climate types in Europe based on GCM-RCM combined projections 

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      open access

      vydavatelská verze

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      Holtanová, Eva

      ;

      Belda, Michal

      ;

      Randriatsara, Herijaona Hani-Roge Hundilida

      ;

      Szabó, Amanda Imola

      ;

      Halenka, Tomáš

      2025

      ,

      Springer

      ,

      Theorectical and Applied Climatology

      ,

      156

      (11)

      Climate classifications represent a convenient tool for an integrated analysis of possible future climate changes. We employ the K & ouml;ppen-Trewartha classification (KTC). While global climate models (GCMs) are the ...

    • Historical changes in drought characteristics and their impact on vegetation cover over Madagascar 

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      open access

      vydavatelská verze

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      Randriatsara, Herijaona Hani-Roge Hundilida

      ;

      Holtanová, Eva

      ;

      Rizwan, Karim

      ;

      Babaousmail, Hassen

      ;

      Rabezanahary, Mirindra Finaritra Tanteliniaina

      ;

      Posset, Kokou Romaric

      ;

      Alupot, Donnata

      ;

      Ayugi, Brian Odhiambo

      2025

      ,

      Copernicus Publ.

      ,

      Natural Hazards and Earth System Science

      ,

      25

      (9)

      Drought has become one of the most devastating natural hazards in recent decades, causing severe vegetation degradation. This study aims to analyze the spatiotemporal characteristics of drought (duration, frequency, severity, ...

    • Oskar Becker on Husserl’s Principle of Transcendental Idealism: Reconstruction and Interpretation 

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      open access

      vydavatelská verze

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      De Santis, Daniele

      2025

      ,

      Husserl Studies

      ,

      41

      (2)

      The paper proposes a systematic reconstruction of Oskar Becker's interpretation of Husserl's principle of transcendental idealism. Three phases will be distinguished in Becker's approach. After a first attempt at understanding ...

    • Spatial Profiling and Prognostic Role of Tumor-Infiltrating CD8+T and CD20+B Cells in Metastatic Clear Cell Renal Cell Carcinoma Treated with Sequential Tyrosine Kinase Inhibitors and Nivolumab 

      původní článek

      open access

      vydavatelská verze

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      Trailin, Andriy

      ;

      Červenková, Lenka

      ;

      Hošek, Petr

      ;

      Pivovarčíková, Kristýna

      ;

      Tkadlecová, Michaela

      ;

      Stránský, Petr

      ;

      Hemminki, Kari Jussi

      ;

      Fiala, Ondřej

      2026

      ,

      Ivyspring International Publisher

      ,

      Journal of Cancer

      ,

      17

      (2)

      Background: Tumor-infiltrating lymphocytes (TILs) are known to influence disease progression and treatment response in clear cell renal cell carcinoma. This study aimed at evaluating the prognostic and predictive relevance ...

    • Familial colorectal cancer: search for novel predisposition genes 

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      Försti, Asta

      ;

      Miao, Beiping

      ;

      Kumar, Abhishek

      ;

      Dymerska Zaremba, Dagmara

      ;

      Marciniak, Magdalena

      ;

      Lubinski, Jan

      ;

      Hemminki, Kari Jussi

      2026

      ,

      Henry Stewart Publications

      ,

      Human Genomics

      ,

      20

      (1)

      BACKGROUND: Family history of colorectal cancer (CRC) and multiple primary CRCs in a single person may indicate inherited CRC predisposition. METHODS: In the present study, we performed whole exome/genome sequencing on ...

    • Jan Blahoslav a jeho obrazy v českém dějepisectví a ve společnosti 

      Jan Blahoslav and his images in Czech historiography and society

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      vydavatelská verze

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      Nešpor, Zdeněk

      2025

      ,

      Evangelická teologická fakulta Univerzity Karlovy

      ,

      Teologická reflexe

      ,

      31

      (2)

      Studie analyzuje moderní historiografický zájem o život a dílo teologa Jednota bratrské Jana Blahoslava a jeho následnou recepci ve společnosti.

    • Má být Česko daňovým rájem pro kryptoaktiva? 

      přednáška

      open access

      vydavatelská verze

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      Málek, Ondřej

      2024

      Poslanecká sněmovna aktuálně projednává zákon navazující na evropský "Balíček pro oblast digitální financí". Ačkoliv právní úprava směřuje zejména na regulaci finančního sektoru, podaný pozměňovací návrh k ní přidal i změny ...