Recent Submissions

  • Infekce lidským papilomavirem (HPV) a gravidita 

    Human papillomavirus (HPV) infection and pregnancy

    original article

    open access

    published version

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    Sehnal, Borek

    ;

    Halaška, Michael

    ;

    Vlk, Radovan

    ;

    Drochýtek, Vít

    ;

    Pichlík, Tomáš

    ;

    Hruda, Martin

    ;

    Robová, Helena

    ;

    Rob, Lukáš

    ;

    Tachezy, Ruth

    2024

    ,

    Epidemiologie, mikrobiologie, imunologie

    ,

    73

    (1)

    Lidský papilomavirus (HPV) je celosvětově nejběžnější sexuálně přenosnou virovou infekcí, která může vést ke vzniku benigních lézí nebo maligních nádorů. Prevalence HPV infekce je u těhotných žen dvakrát vyšší než u ...

  • Akutní infarkt myokardu a preexistující levostranné chlopenní vady 

    lecture

    open access

    published version

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    Muzafarova, Tamilla

    2024

  • Emergence of Escherichia coli ST131 carrying carbapenemase genes, European Union/European Economic Area, August 2012 to May 2024 

    original article

    open access

    accepted version

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    Kohlenberg, Anke

    ;

    Svartström, Olov

    ;

    Apfalter, Petra

    ;

    Hartl, Rainer

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    Bogaerts, Pierre

    ;

    Huang, Te-Din

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    Chudějová, Kateřina

    ;

    Mališová, Lucia

    ;

    Eisfeld, Jessica

    ;

    Sandfort, Mirco

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    Hammerum, Anette M

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    Roer, Louise

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    Räisänen, Kati

    ;

    Dortet, Laurent

    ;

    Bonnin, Rémy A

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    Tóth, Ákos

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    Tóth, Kinga

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    Clarke, Christina

    ;

    Cormican, Martin

    ;

    Griškevičius, Algirdas

    ;

    Khonyongwa, Kirstin

    ;

    Meo, Marie

    ;

    Niedre-Otomere, Baiba

    ;

    Vangravs, Reinis

    ;

    Hendrickx, Antoni Pa

    ;

    Notermans, Daan W

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    Samuelsen, Ørjan

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    Caniça, Manuela

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    Manageiro, Vera

    ;

    Müller, Vilhelm

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    Mäkitalo, Barbro

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    Kramar, Urška

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    Pirs, Mateja

    ;

    Palm, Daniel

    ;

    Monnet, Dominique L

    ;

    Alm, Erik

    ;

    Linkevicius, Marius

    2024

    ,

    Eurosurveillance

    ,

    29

    (47)

    Analysis of 594 isolates of Escherichia coli sequence type (ST)131 and its single locus variants carrying carbapenemase genes from 17 European Union/European Economic Area countries revealed acquisition of 18 carbapenemase ...

  • The out-of-hospital cardiac arrest in patients with acute myocardial infarction and pre-existing aortic stenosis 

    poster

    open access

    published version

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    Muzafarova, Tamilla

    ;

    Moťovská, Zuzana

    ;

    Hlinomaz, Ota

    ;

    Kala, Petr

    ;

    Hromádka, Milan

    ;

    Víchová, Teodora

    ;

    Mrozek, Jan

    ;

    Kettner, Jiří

    ;

    Hutyra, Martin

    ;

    Petr, Róbert

    ;

    Tomasov, Pavol

    ;

    Ioniţă, Oana

    ;

    Jarkovský, Jiří

    2024

  • Prognosis of cardiogenic shock following acute myocardial infarction 

    lecture

    open access

    published version

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    Muzafarova, Tamilla

    ;

    Moťovská, Zuzana

    ;

    Hlinomaz, Ota

    ;

    Kala, Petr

    ;

    Hromádka, Milan

    ;

    Přeček, Jan

    ;

    Mrozek, Jan

    ;

    Matějka, Jan

    ;

    Kettner, Jiří

    ;

    Bis, Josef

    ;

    Jarkovský, Jiří

    2023

  • Prediktory prognózy pacientu s akutním infarktem myokardu komplikovaným iniciálně kardiogenním šokem 

    poster

    open access

    published version

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    Muzafarova, Tamilla

    ;

    Moťovská, Zuzana

    ;

    Hlinomaz, Ota

    ;

    Kala, Petr

    ;

    Hromádka, Milan

    ;

    Přeček, Jan

    ;

    Mrozek, Jan

    ;

    Matějka, Jan

    ;

    Kettner, Jiří

    ;

    Bis, Josef

    ;

    Jarkovský, Jiří

    2023

  • Clinical Characteristics and Outcome of Patients With Acute Myocardial Infarction and Pre-Existing Left Heart Valvular Disease 

    poster

    open access

    published version

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    Muzafarova, Tamilla

    ;

    Moťovská, Zuzana

    ;

    Hlinomaz, Ota

    ;

    Kala, Petr

    ;

    Hromádka, Milan

    ;

    Víchová, Teodora

    ;

    Mrozek, Jan

    ;

    Kettner, Jiří

    ;

    Hutyra, Martin

    ;

    Petr, Róbert

    ;

    Tomasov, Pavol

    ;

    Ioniţă, Oana

    ;

    Jarkovský, Jiří

    2024

  • Isokalorická KETOgenní dieta ZLEPŠUJE insulinovou senzitivitu U OBÉZNÍCH ŽEN 

    poster

    open access

    published version

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    Šebo, Viktor

    ;

    Koudelková, Kateřina

    ;

    Krauzová, Eva

    ;

    Wilhelm, Marek

    ;

    Heniková, Marina

    ;

    Gojda, Jan

    ;

    Rossmeislová, Lenka

    ;

    Šiklová, Michaela

    2023

  • Polymorphisms in transcription factor binding sites and enhancer regions and pancreatic ductal adenocarcinoma risk 

    original article

    open access

    published version

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    Ünal, Pelin

    ;

    Lu, Ye

    ;

    Bueno-de-Mesquita, Bas

    ;

    van Eijck, Casper H. J.

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    Talar-Wojnarowska, Renata

    ;

    Szentesi, Andrea

    ;

    Gazouli, Maria

    ;

    Kreivenaite, Edita

    ;

    Tavano, Francesca

    ;

    Małecka-Wojciesko, Ewa

    ;

    Erőss, Bálint

    ;

    Oliverius, Martin

    ;

    Bunduc, Stefania

    ;

    Nóbrega Aoki, Mateus

    ;

    Vodičková, Ludmila

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    Boggi, Ugo

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    Giaccherini, Matteo

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    Kondrackiene, Jurate

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    Chammas, Roger

    ;

    Palmieri, Orazio

    ;

    Theodoropoulos, George E.

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    Bijlsma, Maarten F.

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    Basso, Daniela

    ;

    Mohelníková-Duchoňová, Beatrice

    ;

    Souček, Pavel

    ;

    Izbicki, Jakob R

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    Kiudelis, Vytautas

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    Vanella, Giuseppe

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    Arcidiacono, Paolo Giorgio

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    Włodarczyk, Barbara

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    Hackert, Thilo

    ;

    Schöttker, Ben

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    Uzunoglu, Faik G.

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    Bambi, Franco

    ;

    Goetz, Mara

    ;

    Hlaváč, Viktor

    ;

    Brenner, Hermann

    ;

    Perri, Francesco

    ;

    Carrara, Silvia

    ;

    Landi, Stefano

    ;

    Hegyi, Péter

    ;

    Dijk, Frederike

    ;

    Maiello, Evaristo

    ;

    Capretti, Giovanni

    ;

    Testoni, Sabrina Gloria Giulia

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    Petrone, Maria Chiara

    ;

    Stocker, Hannah

    ;

    Ermini, Stefano

    ;

    Archibugi, Livia

    ;

    Gentiluomo, Manuel

    ;

    Cavestro, Giulia Martina

    ;

    Pezzilli, Raffaele

    ;

    Di Franco, Gregorio

    ;

    Milanetto, Anna Caterina

    ;

    Sperti, Cosimo

    ;

    Neoptolemos, John P.

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    Morelli, Luca

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    Vokáčová, Klára

    ;

    Pasquali, Claudio

    ;

    Lawlor, Rita T

    ;

    Bazzocchi, Francesca

    ;

    Kupcinskas, Juozas

    ;

    Capurso, Gabriele

    ;

    Campa, Daniele

    ;

    Canzian, Federico

    2024

    ,

    Human Genomics

    ,

    18

    (February)

    Genome-wide association studies (GWAS) are a powerful tool for detecting variants associated with complex traits and can help risk stratification and prevention strategies against pancreatic ductal adenocarcinoma (PDAC). ...

  • Adenotonsillar pathology in mucopolysaccharidoses - lysosomal storage predominates in paracortical CD63+ cells 

    original article

    open access

    published version

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    Murgašová, Lenka

    ;

    Hůlková, Helena

    ;

    Barešová, Veronika

    ;

    Jurovčík, Michal

    ;

    Stříteský, Jan

    ;

    Jurickova, Katarina

    ;

    Magner, Martin

    ;

    Sikora, Jakub

    2024

    ,

    Virchows Archiv

    ,

    484

    (1)

    Despite the adenoids are regularly removed in patients with mucopolysaccharidoses (MPS), the underlying tissue and cellular pathologies remain understudied. We characterized an (immuno)histopathologic and ultrastructural ...

  • The Czech National MS Registry (ReMuS): Data trends in multiple sclerosis patients whose first disease-modifying therapies were initiated from 2013 to 2021 

    original article

    open access

    published version

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    Šťastná, Dominika

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    Drahota, Jiří

    ;

    Lauer, Michal

    ;

    Mazouchová, Aneta

    ;

    Meňkyová, Ingrid

    ;

    Adámková, Jana

    ;

    Ampapa, Radek

    ;

    Dufek, Michal

    ;

    Grunermelova, Marketa

    ;

    Hradilek, Pavel

    ;

    Kubala Havrdová, Eva

    ;

    Mareš, Jan

    ;

    Martínková, Alena

    ;

    Pavelek, Zbyšek

    ;

    Peterka, Marek

    ;

    Recmanová, Eva

    ;

    Ročková, Petra

    ;

    Štětkářová, Ivana

    ;

    Štourač, Pavel

    ;

    Vachová, Marta

    ;

    Horáková, Dana

    2024

    ,

    Biomedical Papers

    ,

    168

    (3)

    AIMS: Multiple sclerosis treatment strategies are changing in the Czech Republic. According to data from 2013-2021, the proportion of patients starting high-efficacy disease-modifying therapies is increasing. In this survey, ...

  • Amiodarone but not propafenone impairs bioenergetics and autophagy of human myocardial cells 

    original article

    open access

    published version

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    Krajčová, Adéla

    ;

    Němcová, Vlasta

    ;

    Halačová, Milada

    ;

    Waldauf, Petr

    ;

    Balík, Martin

    ;

    Duška, František

    2023

    ,

    Toxicology and Applied Pharmacology

    ,

    477

    (October)

    Cardiac and extra-cardiac side effects of common antiarrhythmic agents might be related to drug-induced mitochondrial dysfunction. Supratherapeutic doses of amiodarone have been shown to impair mitochondria in animal ...

  • Outcomes Of Patients With Myocardial Infarction And Cardiogenic Shock Treated With Culprit Vessel-Only Versus Multivessel Primary PCI 

    original article

    open access

    published version

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    Hlinomaz, Ota

    ;

    Moťovská, Zuzana

    ;

    Kala, Petr

    ;

    Hromádka, Milan

    ;

    Přeček, Jan

    ;

    Mrózek, Jan

    ;

    Červinka, Pavel

    ;

    Kettner, Jiří

    ;

    Matějka, Jan

    ;

    Zohoor, Ahmad

    ;

    Bis, Josef

    ;

    Jarkovský, Jiří

    2024

    ,

    Hellenic Journal of Cardiology

    ,

    76

    (MAR-APR)

    INTRODUCTION AND OBJECTIVES: Multivessel primary percutaneous coronary intervention (pPCI) is still often used in patients with ST-elevation myocardial infarction (STEMI) and cardiogenic shock (CS). The study aimed to ...

  • High incidence of occult familial SDHD cases amongst Czech patients with head and neck paragangliomas 

    original article

    open access

    published version

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    Guha, Anasuya

    ;

    Vícha, Aleš

    ;

    Zelinka, Tomáš

    ;

    Kaňa, Martin

    ;

    Musil, Zdeněk

    ;

    Pacák, Karel

    ;

    Betka, Jan

    ;

    Chovanec, Martin

    ;

    Plzák, Jan

    ;

    Bouček, Jan

    2023

    ,

    Frontiers in Endocrinology

    ,

    14

    (December)

    INTRODUCTION: Head and neck paragangliomas (HNPGLs) are rare neuroendocrine tumors, which are mostly benign in nature. Amongst all genes, Succinate Dehydrogenase Subunit D (SDHD) is the most commonly mutated in familial ...

  • Molecular Screening in Anaplastic Lymphoma Kinase–Positive Anaplastic Large Cell Lymphoma: Anaplastic Lymphoma Kinase Analysis, Next-Generation Sequencing Fusion Gene Detection, and T-Cell Receptor Immunoprofiling 

    original article

    open access

    published version

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    Kalinová, Markéta

    ;

    Mrhalová, Marcela

    ;

    Kabíčková, Edita

    ;

    Svatoň, Michael

    ;

    Skotnicová, Aneta

    ;

    Prouzová, Zuzana

    ;

    Křenová, Zdenka

    ;

    Kolenová, Alexandra

    ;

    Divoká, Martina

    ;

    Froňková, Eva

    ;

    Kodet, Roman

    2024

    ,

    Modern Pathology

    ,

    37

    (3)

    Anaplastic lymphoma kinase-positive anaplastic large cell lymphoma (ALK+ ALCL) originates from the T-lineage and is marked by rearrangements of the ALK gene. Over ten fusion partners with the ALK gene are known, with the ...

  • Frentizole derivatives with mTOR inhibiting and senomorphic properties 

    original article

    open access

    published version

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    Chrienová, Zofia

    ;

    Ryšánek, David

    ;

    Novák, Josef

    ;

    Vašicová, Pavla

    ;

    Olekšák, Patrik

    ;

    Andrys, Rudolf

    ;

    Skarka, Adam

    ;

    Dumanovic, Jelena

    ;

    Milovanovic, Zoran

    ;

    Jacevic, Vesna

    ;

    Chvojková, Markéta

    ;

    Holubová, Kristína

    ;

    Valeš, Karel

    ;

    Skoupilová, Veronika

    ;

    Valko, Marian

    ;

    Jomová, Klaudia

    ;

    Alomar, Suliman Y.

    ;

    Botelho, Fernanda D.

    ;

    Franca, Tanos C. C.

    ;

    Kuča, Kamil

    ;

    Hodný, Zdeněk

    ;

    Nepovimová, Eugenie

    2023

    ,

    Biomedicine & Pharmacotherapy

    ,

    167

    (November)

    Frentizole is immunosuppressive drug with low acute toxicity and lifespan-prolonging effect. Recently, frentizole's potential to disrupt toxic amyloid β (Aβ) - Aβ-binding alcohol dehydrogenase (ABAD) interaction in ...

  • Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists 

    original article

    open access

    published version

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    Chvojková, Markéta

    ;

    Kolář, David

    ;

    Kováčová, Katarína

    ;

    Čejková, Lada

    ;

    Misiachna, Anna

    ;

    Hakenová, Kristina

    ;

    Górecki, Lukáš

    ;

    Horák, Martin

    ;

    Korábečný, Jan

    ;

    Soukup, Ondřej

    ;

    Valeš, Karel

    2024

    ,

    Biomedicine & Pharmacotherapy

    ,

    176

    (July)

    Therapeutic options for Alzheimer's disease are limited. Dual compounds targeting two pathways concurrently may enable enhanced effect. The study focuses on tacrine derivatives inhibiting acetylcholinesterase (AChE) and ...

  • How to invasively assess left ventricular function and its efficiency of work 

    summarizing article

    open access

    published version

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    Povišer, Lukáš

    ;

    Čurila, Karol

    2024

    ,

    Cor et Vasa

    ,

    66

    (1)

    Effective performance of the left ventricle requires the maintenance of a cardiac output as demanded by the systemic circulation without a high hemodynamic cost or pressure and without a high metabolic cost or oxygen demand ...

  • The role of adipogenic capacity and dysfunctional subcutaneous adipose tissue in the inheritance of type 2 diabetes mellitus: cross-sectional study 

    original article

    open access

    published version

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    Šiklová, Michaela

    ;

    Šrámková, Veronika

    ;

    Koc, Michal

    ;

    Krauzová, Eva

    ;

    Čížková, Terezie

    ;

    Ondrůjová, Barbora

    ;

    Wilhelm, Marek

    ;

    Varaliová, Zuzana

    ;

    Kuda, Ondřej

    ;

    Neubert, Jana

    ;

    Lambert, Lukáš

    ;

    Elkalaf, Moustafa

    ;

    Gojda, Jan

    ;

    Rossmeislová, Lenka

    2024

    ,

    Obesity

    ,

    32

    (3)

    OBJECTIVE: This study tested the hypothesis that limited subcutaneous adipose tissue (SAT) expansion represents a primary predisposition to the development of type 2 diabetes mellitus (T2DM), independent of obesity, and ...

  • Utilization of healthcare services in acute myocardial infarction and the risk of out-of-hospital cardiac death 

    letter to the editors

    open access

    published version

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    Moťovská, Zuzana

    ;

    Hlinomaz, Ota

    ;

    Hromádka, Milan

    ;

    Mrózek, Jan

    ;

    Přeček, Jan

    ;

    Kala, Petr

    ;

    Muzafarova, Tamilla

    ;

    Kettner, Jiří

    ;

    Matějka, Jan

    ;

    Bis, Josef

    ;

    Červinka, Pavel

    ;

    Tomašov, Pavol

    ;

    Klechová, Anna

    ;

    Šanca, Ondřej

    ;

    Jarkovský, Jiří

    2024

    ,

    Panminerva Medica

    ,

    66

    (1)

    COVID-19 represented a significant challenge to cardiovascular (cV) medicine research, treatment, prevention, and, to a considerable extent, case management. The global pandemic viral infection increased the risk of ...

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