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The evaluation of an automated mariPOC SARS-CoV-2 antigen test compared to RT-qPCR SARS-CoV-2 assay and comparison of its sensitivity in Delta- and Omicron-variant samples
(2022)
Background The rapid diagnostics tests for SARS-CoV-2 antigen vary in their sensitivities, and moreover, genomic mutations may further affect the performance of the assays. We aimed to evaluate the analytical performance ...
COVID-19 Vaccination among Czech Dentists
(2022)
This work describes and evaluates vaccination against COVID-19 among members of the Czech Dental Chamber during the pre-booster vaccination phase. A cross-sectional online survey was conducted between 23 June and 4 September ...
Specific Immune Response Against SARS-CoV-2
(2023)
The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide. For effective treatment and introduction of appropriate antipandemic measures, it is necessary to understand the development ...
Vývoj metodiky pro analýzu T-buněčné odpovědi proti viru SARS-CoV-2
Development of a procedure for the analysis of the T-cell response against SARS-CoV-2 virus
V roce 2020 způsobil koronavirus SARS-CoV-2 pandemii onemocnění covid-19. Pro detekci buněčné odpovědi vyvolané infekcí tímto virem byl vyvinut vysoce citlivý test ELISPOT detekující specifické lymfocyty T produkující ...
Characterization of the evolutionary and virological aspects of mutations in the receptor binding motif of the SARS-CoV-2 spike protein
(2023)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has substantially diversified during the pandemic, resulting in the successive emergence of variants characterized by various mutations. It has been observed ...
Specific Immunity to SARS-CoV-2 Infection
(Česká zemědělská univerzita, Praha, 2024)
The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide.For effective treatment and introduction of appropriate anti-pandemic measures, it is necessary tounderstand the development ...
Can variants, reinfection, symptoms and test types affect COVID-19 diagnostic performance? A large-scale retrospective study of AG-RDTs during circulation of Delta and Omicron variants, Czechia, December 2021 to February 2022
(2023)
BackgroundThe sensitivity and specificity of selected antigen detection rapid diagnostic tests (AG-RDTs) for SARS-CoV-2 were determined in the unvaccinated population when the Delta variant was circulating. Viral loads, ...