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Specific Immune Response Against SARS-CoV-2
(2023)
The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide. For effective treatment and introduction of appropriate antipandemic measures, it is necessary to understand the development ...
Human polyomaviruses in psoriasis patients on biologic treatment
(2023)
Biologic therapy poses a higher risk of viral infection for patients, however current knowledge of human polyomavirus infection in psoriasis patients is stilllimited. In this study, we evaluate the prevalence of BK ...
Skin and oral virome in psoriasis patients on biologic therapy
(Praha, 2022)
The viral communities represent the most abundant microbiota population in humans. Viruses, together with other microbiota such as bacteria and fungi, form a dynamic ecosystem that influences the health of the host. The ...
Vývoj metodiky pro analýzu T-buněčné odpovědi proti viru SARS-CoV-2
Development of a procedure for the analysis of the T-cell response against SARS-CoV-2 virus
V roce 2020 způsobil koronavirus SARS-CoV-2 pandemii onemocnění covid-19. Pro detekci buněčné odpovědi vyvolané infekcí tímto virem byl vyvinut vysoce citlivý test ELISPOT detekující specifické lymfocyty T produkující ...
The Virome of Healthy Honey Bee Colonies: Ubiquitous Occurrence of Known and New Viruses in Bee Populations
(2022)
Honey bees are globally important pollinators threatened by many different pathogens, including viruses. We investigated the virome of honey bees collected at the end of the beekeeping season (August/September) in Czechia, ...
Torque teno virus infection among psoriasis patients on biologic therapy
(2023)
Torque teno virus (TTV) is a ubiquitous member of the healthy human virome with broad tissue tropism. TTV can induce chronic active infection without clinical manifestations. Although little is known about ...
Genome sequence of parvovirus from budgerigar (Melopsittacus undulatus)
(2023)
Here, we report a parvovirus genome identified in Melopsittacus undulatus.The genome is 4,547 bp long and codes for two major open reading frames (ORFs): the non-structural replicase protein 1 (NS1) and the structural ...
The differences in virome from distinct anatomical locations in psoriasis patients
(Česká zemědělská univerzita, Praha, 2024)
Psoriasis, a chronic autoimmune inflammatory disorder affecting 2-3% of the global population,exhibits a multifactorial aetiology with a significant genetic component and triggers such as trauma orinfection.
Varroa destructor parasitism and Deformed wing virus infection in honey bees are linked to peroxisome-induced pathways
(2024)
The ectoparasitic mite Varroa destructor transmits and triggers viral infections that have deleterious effects on honey bee colonies worldwide. We performed a manipulative experiment in which worker bees collected at ...
Specific Immunity to SARS-CoV-2 Infection
(Česká zemědělská univerzita, Praha, 2024)
The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide.For effective treatment and introduction of appropriate anti-pandemic measures, it is necessary tounderstand the development ...