Repozitář publikační činnosti UK: Poslední příspěvky

Zobrazují se záznamy 481-500 z 938

    • Carl Schmitt and Democratic Backsliding 

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      Karolewski, Pawel Ireneusz

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      Libin, Xie

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      Patapan, Haig

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      Halmai, Gabor

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      Kutay, Acar

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      Guasti, Petra

      ;

      Scheuerman, William E.

      2023

      ,

      Contemporary Political Theory

      ,

      22

      (3)

      This Critical Exchange suggests that Schmittian inspirations abound in countries that experience democratic backsliding. Sometimes, Schmitt's ideas are used explicitly, but more often they are implicit in the actions of ...

    • Acute Effects of Isometric Conditioning Activity on the Viscoelastic Properties of Muscles and Sprint and Jumping Performance in Handball Players 

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      Krzysztofik, Michal

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      Spieszny, Michal

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      Trybulski, Robert

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      Wilk, Michal

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      Pisz, Anna

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      Kolinger, Dominik

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      Filip-Stachnik, Aleksandra

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      Šťastný, Petr

      2023

      ,

      Journal of Strength and Conditioning Research

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      37

      (7)

      Krzysztofik, M, Spieszny, M, Trybulski, R, Wilk, M, Pisz, A, Kolinger, D, Filip-Stachnik, A, and Stastny, P. Acute effects of isometric conditioning activity on the viscoelastic properties of muscles and sprint and jumping ...

    • Sleep quality and sleep routines as mediators of stressors and life satisfaction in Czech university students: a structural equation model 

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      Prokeš, Michaela

      2023

      ,

      Frontiers in Psychology

      ,

      2023

      (14)

      Introduction: Sleep is especially important to overall well-being. Some aspects of sleep have been well documented, for example sleep quantity and its effect on well-being, but the value of a consistent sleep routine remains ...

    • Reliability of the saliva self-sampling with and without supervision 

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      Jaklová Dytrtová, Jana

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      Dytrtová, Radmila

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      Kovač, Ishak

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      Šteffl, Michal

      ;

      Jakl, Michal

      2023

      ,

      Acta Universitatis Carolinae. Kinanthropologica

      ,

      59

      (1)

      One of the least invasive sampling methods suitable for self-sampling is saliva spitting. The aim of this study is to evaluate the suitability of saliva self-sampling for unsupervised testing. Two self-sampling strategies ...

    • Clonal origin and development of high hyperdiploidy in childhood acute lymphoblastic leukaemia 

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      Woodward, Eleanor L

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      Yang, Minjun

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      Moura-Castro, Larissa H

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      van den Bos, Hilda

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      Gunnarsson, Rebeqa

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      Olsson-Arvidsson, Linda

      ;

      Spierings, Diana C J

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      Castor, Anders

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      Duployez, Nicolas

      ;

      Žaliová, Markéta

      ;

      Zuna, Jan

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      Johansson, Bertil

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      Foijer, Floris

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      Paulsson, Kajsa

      2023

      ,

      Nature Communications

      ,

      14

      (1)

      High hyperdiploid acute lymphoblastic leukemia (HeH ALL), one of the most common childhood malignancies, is driven by nonrandom aneuploidy (abnormal chromosome numbers) mainly comprising chromosomal gains. In this study, ...

    • Constitutively active Lyn kinase causes a cutaneous small vessel vasculitis and liver fibrosis syndrome 

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      de Jesus, Adriana A

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      Chen, Guibin

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      Yang, Dan

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      Brdicka, Tomas

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      Ruth, Natasha M

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      Bennin, David

      ;

      Cebecauerová, Dita

      ;

      Malcová, Hana

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      Freeman, Helen

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      Martin, Neil

      ;

      Švojgr, Karel

      ;

      Passo, Murray H

      ;

      Bhuyan, Farzana

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      Alehashemi, Sara

      ;

      Rastegar, Andre T

      ;

      Uss, Katsiaryna

      ;

      Kardava, Lela

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      Marrero, Bernadette

      ;

      Đurić, Iris

      ;

      Omoyinmi, Ebun

      ;

      Peldová, Petra

      ;

      Lee, Chyi-Chia Richard

      ;

      Kleiner, David E

      ;

      Hadigan, Colleen M

      ;

      Hewitt, Stephen M

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      Pittaluga, Stefania

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      Carmona-Rivera, Carmelo

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      Calvo, Katherine R

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      Shah, Nirali

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      Balaščaková, Miroslava

      ;

      Fink, Danielle L

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      Kotalová, Radana

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      Paračková, Zuzana

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      Peterková, Lucie

      ;

      Kužílková, Daniela

      ;

      Campr, Vít

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      Šrámková, Lucie

      ;

      Biancotto, Angelique

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      Brooks, Stephen R

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      Manes, Cameron

      ;

      Meffre, Eric

      ;

      Harper, Rebecca L

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      Kuehn, Hyesun

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      Kaplan, Mariana J

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      Brogan, Paul

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      Rosenzweig, Sergio D

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      Merchant, Melinda

      ;

      Deng, Zuoming

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      Huttenlocher, Anna

      ;

      Moir, Susan L

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      Kuhns, Douglas B

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      Boehm, Manfred

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      Škvárová Kramarzová, Karolina

      ;

      Goldbach-Mansky, Raphaela

      2023

      ,

      Nature Communications

      ,

      14

      (1)

      Neutrophilic inflammation is a hallmark of many monogenic autoinflammatory diseases; pathomechanisms that regulate extravasation of damaging immune cells into surrounding tissues are poorly understood. Here we identified ...

    • STING agonists induce robust cytokine secretion and rapid monocyte cell death in peripheral blood mononuclear cells 

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      Pimková Polidarová, Markéta

      ;

      Hirsch, Ivan

      ;

      Brázdová, Andrea

      ;

      Grantz Šašková, Klára

      2023

      The cyclic-GMP-AMP synthase - stimulator of interferon genes (cGAS-STING) pathway plays a central role in recognition of the double-stranded DNA in cytoplasm, a sign of cell damage or infection. Upon activation, the pathway ...

    • STING agonist-induced cytokine production with anti-HBV activity is accompanied by immunogenic cell death of monocytes 

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      Pimková Polidarová, Markéta

      ;

      Hirsch, Ivan

      ;

      Berehovska, Olena

      ;

      Janovec, Václav

      ;

      Brázdová, Andrea

      ;

      Grantz Šašková, Klára

      2023

      The cyclic-GMP-AMP synthase - stimulator of interferon genes (cGAS-STING) pathwayrecognizes cytosolic double-stranded DNA (dsDNA), a sign of viral infection or cell damage.Activation of the pathway stimulates immune cells ...

    • Serum but not cerebrospinal fluid levels of allantoin are increased in de novo Parkinson's disease 

      původní článek

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      Hasíková, Lenka

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      Závada, Jakub

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      Serranová, Tereza

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      Kozlík, Petr

      ;

      Kalíková, Květa

      ;

      Kotačková, Lenka

      ;

      Trnka, Jiří

      ;

      Zogala, David

      ;

      Šonka, Karel

      ;

      Růžička, Evžen

      ;

      Dušek, Petr

      2023

      ,

      NPJ Parkinsons Disease

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      9

      (1)

      Oxidative stress supposedly plays a role in the pathogenesis of Parkinson's disease (PD). Uric acid (UA), a powerful antioxidant, is lowered in PD while allantoin, the oxidation product of UA and known biomarker of oxidative ...

    • Magnetic susceptibility changes in the brainstem reflect REM sleep without atonia severity in isolated REM sleep behavior disorder 

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      Nepožitek, Jiří

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      Varga, Zsóka

      ;

      Dostálová, Simona

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      Peřinová, Pavla

      ;

      Keller, Jiří

      ;

      Robinson, Simon

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      Ibarburu Lorenzo Y Losada, Veronika

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      Příhodová, Iva

      ;

      Bezdíček, Ondřej

      ;

      Růžička, Evžen

      ;

      Šonka, Karel

      ;

      Dušek, Petr

      2023

      ,

      NPJ Parkinsons Disease

      ,

      9

      (1)

      REM sleep without atonia (RWA) is the hallmark of isolated REM sleep behavior disorder (iRBD) and is caused by neurodegeneration of brainstem structures. Previously, quantitative susceptibility mapping (QSM) was shown to ...

    • Kapitoly z kreativní hudební výchovy 

      Chapters on Creative Music Education

      učebnice pro VŠ

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      Jiřičková, Jiřina

      ;

      Kuříková, Michaela

      ;

      Novotná, Magdalena

      ;

      Kozánková, Olga

      ;

      Řepová, Karolína

      2023

      ,

      Praha

      ,

      Univerzita Karlova, Pedagogická fakulta

      Vysokoškolská učebnice Kapitoly z kreativní hudební výchovy je publikačním výstupem projektu Kreativní interakce jako zdroj motivace a inovace ve výuce vysokoškolských pedagogů a v pregraduální přípravě pedagogů HV, ...

    • Understanding the Effect of Aspartate Hydroxylase Inhibition On T Cell-Mediated Immunity Using Single-Cell RNA Sequencing 

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      Johari, Shweta Dilip

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      Krausová, Kateřina

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      Číhařová, Barbora

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      Poláková, Ingrid

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      Olsen, Mark

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      Šmahel, Michal

      2023

      ,

      Neuvedeno

      Overexpression of aspartate β-hydroxylase (ASPH) was found in 70-90% of solid tumors but is negligible in normal tissues. Increased ASPH contributes to tumor cell proliferation, migration, and invasion but can also affect ...

    • Can variants, reinfection, symptoms and test types affect COVID-19 diagnostic performance? A large-scale retrospective study of AG-RDTs during circulation of Delta and Omicron variants, Czechia, December 2021 to February 2022 

      původní článek

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      Kliegr, Tomáš

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      Jarkovský, Jiří

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      Jiřincová, Helena

      ;

      Kuchař, Jaroslav

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      Karel, Tomáš

      ;

      Chudán, David

      ;

      Vojíř, Stanislav

      ;

      Zavřel, Michal

      ;

      Šanca, Ondřej

      ;

      Tachezy, Ruth

      2023

      ,

      Eurosurveillance

      ,

      28

      (38)

      Background: The sensitivity and specificity of selected antigen detection rapid diagnostic tests (AG-RDTs) for SARS-CoV-2 were determined in the unvaccinated population when the Delta variant was circulating. Viral loads, ...

    • Human polyomaviruses in psoriasis patients on biologic treatment 

      abstrakt v elektronické podobě

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      Saláková, Martina

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      Rob, Filip

      ;

      Hugo, Jan

      ;

      Šmahelová, Jana

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      Hamšíková, Eva

      ;

      Ludvíková, Viera

      ;

      Gkalpakiotis, Spyridon

      ;

      Boháč, Petr

      ;

      Tachezy, Ruth

      2023

      ,

      Neuveden

      Biologic therapy poses a higher risk of viral infection for patients, however current knowledge of human polyomavirus infection in psoriasis patients is stilllimited. In this study, we evaluate the prevalence of BK ...

    • Specific Immune Response Against SARS-CoV-2 

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      Vránová, Lucie

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      Poláková, Ingrid

      ;

      Tachezy, Ruth

      ;

      Vaníková, Šárka

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      Saláková, Martina

      ;

      Musil, Jan

      ;

      Vaníčková, Marie

      ;

      Vencálek, Ondřej

      ;

      Holub, Michal

      ;

      Bohoněk, Miloš

      ;

      Beran, Ondřej

      ;

      Řezáč, David

      ;

      Dresler, Jiří

      ;

      Kabíčková, Hana

      ;

      Šmahel, Michal

      2023

      ,

      neuveden

      The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide. For effective treatment and introduction of appropriate antipandemic measures, it is necessary to understand the development ...

    • Combined Approach to Leukemic Differentiation Using Transcription Factor PU.1-Enhancing Agents 

      původní článek

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      Bašová, Petra

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      Paszeková, Helena

      ;

      Minařík, Ľubomír

      ;

      Dluhošová, Martina

      ;

      Burda, Pavel

      ;

      Stopka, Tomáš

      2022

      ,

      International Journal of Molecular Sciences [online]

      ,

      23

      (12)

      The transcription factor PU.1 (Purine-rich DNA binding, SPI1) is a key regulator of hematopoiesis, whose level is influenced by transcription through its enhancers and its post-transcriptional degradation via microRNA-155 ...

    • Vinylphosphonate-based cyclic dinucleotides enhance STING-mediated cancer immunotherapy 

      původní článek

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      Dejmek, Milan

      ;

      Brázdová, Andrea

      ;

      Otava, Tomáš

      ;

      Pimková Polidarová, Markéta

      ;

      Klima, Martin

      ;

      Smola, Miroslav

      ;

      Vavřina, Zdeněk

      ;

      Buděšínský, Miloš

      ;

      Dračínský, Martin

      ;

      Liboska, Radek

      ;

      Bouřa, Evžen

      ;

      Birkuš, Gabriel

      ;

      Nencka, Radim

      2023

      ,

      European Journal of Medicinal Chemistry

      ,

      259

      (November)

      Cyclic dinucleotides (CDNs) trigger the cyclic GMP-AMP synthase-stimulator of interferon genes (cGAS-STING) pathway, which plays a key role in cytosolic DNA sensing and thus in immunomodulation against infections, cell ...

    • The crystal structure of bis(1H-pyrazole-carboxamidine-κN,N′)bis(nitrato-κO)-copper(II), C8H12CuN10O6 

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      Kohúteková, Soňa

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      Matulková, Irena

      ;

      Císařová, Ivana

      ;

      Němec, Ivan

      2023

      ,

      Zeitschrift für Kristallographie - New Crystal Structures

      ,

      238

      (2)

      C8H12CuN10O6, triclinic, P1 (no. 2), a = 7.6063(5) Å, b = 9.3072(7) Å, c = 10.8485(8) Å, alpha = 81.370(2)°, beta = 75.503(2)°, gamma = 84.756(2)° V = 733.97(9) Å(3), Z = 2, R-gt(F) = 0.0515, wR(ref)(F-2) = 0.1194, T =120(2) K.

    • Minimal residual disease in BCR::ABL1-positive acute lymphoblastic leukemia: different significance in typical ALL and in CML-like disease 

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      Zuna, Jan

      ;

      Hovorková, Lenka

      ;

      Krotká, Justina

      ;

      Koehrmann, Amelie

      ;

      Bardini, Michela

      ;

      Winkowska, Lucie

      ;

      Froňková, Eva

      ;

      Alten, Julia

      ;

      Koehler, Rolf

      ;

      Eckert, Cornelia

      ;

      Brizzolara, Lisa

      ;

      Trkova, Marie

      ;

      Stuchlý, Jan

      ;

      Zimmermann, Martin

      ;

      De Lorenzo, Paola

      ;

      Valsecchi, Maria Grazia

      ;

      Conter, Valentino

      ;

      Starý, Jan

      ;

      Schrappe, Martin

      ;

      Biondi, Andrea

      ;

      Trka, Jan

      ;

      Žaliová, Markéta

      ;

      Cazzaniga, Giovanni

      ;

      Cario, Gunnar

      2022

      ,

      Leukemia

      ,

      36

      (23)

      Recently, we defined "CML-like" subtype of BCR::ABL1-positive acute lymphoblastic leukemia (ALL), resembling lymphoid blast crisis of chronic myeloid leukemia (CML). Here we retrospectively analyzed prognostic relevance ...

    • Restored biosynthetic pathways induced by MSCs serve as rescue mechanism in leukemia cells after L-asparaginase therapy 

      letter to the editors

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      Alquezar Artieda, Natividad

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      Kužílková, Daniela

      ;

      Roberts, Jennie

      ;

      Hložková, Kateřina

      ;

      Pecinova, Alena

      ;

      Pecina, Petr

      ;

      Zwyrtková, Martina

      ;

      Potůčková, Eliška

      ;

      Kavan, Daniel

      ;

      Heřmanová, Ivana

      ;

      Žaliová, Markéta

      ;

      Novák, Petr

      ;

      Mracek, Tomas

      ;

      Šrámková, Lucie

      ;

      Tennant, Daniel A

      ;

      Trka, Jan

      ;

      Starková, Júlia

      2023

      ,

      Blood Advances

      ,

      7

      (10)

      L-asparaginase (ASNase), the drug included on the World Health Organization's List of EssentialMedicines, is irreplaceable in the front-line treatment of childhood acute lymphoblastic leukemia(ALL)1 . However, the relapse ...