Zobrazují se záznamy 521-540 z 938

    • Přenos výzkumu do praxe: tvorba a implementace metodiky měření kvality paliativní a hospicové péče v ČR 

      Transfer of research into practice: development and implementation of a methodology for measuring the quality of palliative and hospice care in the Czech Republic

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      Žáčková, Lucie

      ;

      Loučka, Martin

      2023

      ,

      Fórum sociální politiky

      ,

      17

      (2)

      Článek se zabývá způsobem a výsledky přenosu výzkumu do praxe, a to na příkladu tvorby a implementace metodiky proměření kvality paliativní a hospicové péče v ČR. První část článku se věnuje východiskům rychle se rozvíjejícího ...

    • Transcripts of vaccinia virus postreplicative genes do not contain a 5' methylguanosine cap 

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      Vopálenský, Václav

      ;

      Sýkora, Michal

      ;

      Mělková, Zora

      ;

      Barvík, Ivan

      ;

      Mašek, Tomáš

      ;

      Horáčková, Kamila

      ;

      Pospíšek, Martin

      2023

      ,

      The 28th Annual Meeting of the RNA Society

      Vaccinia virus (VACV) is a prototypical poxvirus originally used for eradication of smallpox. Investigation into VACV mRNAs carried out almost half a century agosubstantially contributed to the fundamental discovery of the ...

    • Loss of ADAR1 protein induces changes in small RNA landscape in hepatocytes 

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      Roučová, Kristina

      ;

      Vopálenský, Václav

      ;

      Mašek, Tomáš

      ;

      Provazník, Jan

      ;

      Landry, Jonathan

      ;

      Azevedo, Nayara

      ;

      Ehler, Edvard

      ;

      Beneš, Vladimír

      ;

      Pospíšek, Martin

      2023

      ,

      The 28th Annual Meeting of the RNA Society

      In recent years, numerous evidence has been accumulated about the extent of A-to-I editing in human RNAs and the key role ADAR1 plays in the cellular editing machinery and cellular antiviral response. It has been shown ...

    • STING agonists induce monocyte depletion with characteristics of multiple regulated cell deaths 

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      Pimková Polidarová, Markéta

      ;

      Hirsch, Ivan

      ;

      Brázdová, Andrea

      ;

      Grantz Šašková, Klára

      2023

      ,

      9th Prague-Weizmann Summer School in Drug Discovery & Development

      Double-stranded DNA and cyclic dinucleotides activate the cyclic-GMP-AMP synthase - stimulator of interferon genes (cGAS-STING) pathway, which leads to the production of type I interferons (IFNs) and proinflammatory cytokines ...

    • "Ouch!" or "Aah!": Are Vocalizations of 'Laugh', 'Neutral', 'Fear', 'Pain' or 'Pleasure' Reliably Rated? 

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      Binter, Jakub

      ;

      Boschetti, Silvia

      ;

      Hladký, Tomáš

      ;

      Prossinger, Hermann

      2023

      ,

      Human Ethology

      ,

      2023

      (38)

      Our research consisted of two studies focusing on the probability of humans being able to perceive the difference between valence of human vocalizations of high (pain, pleasure and fear) and low intensity (laugh and neutral ...

    • Book review: The digital is kid stuff: Making creative laborers for a precarious economy 

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      Šimková, Karolína

      2023

      ,

      Journal of Media Literacy Education [online]

      ,

      15

      (1)

      This article is a review of the book The digital is kid stuff: Making creative laborers for a precarious economy by Josef Nguyen. Through chapters on children's widely popular game Minecraft, the DIY magazine for parents ...

    • Sequencing-based analysis of clonal evolution of 25 mantle cell lymphoma patients at diagnosis and after failure of standard immunochemotherapy 

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      Karolová, Jana

      ;

      Kazantsev, Dmitry

      ;

      Svatoň, Michael

      ;

      Tušková, Liliana

      ;

      Forsterová, Kristina

      ;

      Maláriková, Diana

      ;

      Benešová, Kateřina

      ;

      Heizer, Tomáš

      ;

      Dolníková, Alexandra

      ;

      Klánová, Magdalena

      ;

      Winkowska, Lucie

      ;

      Svobodová, Karla

      ;

      Hojný, Jan

      ;

      Krkavcová, Eva

      ;

      Froňková, Eva

      ;

      Zemanová, Zuzana

      ;

      Trněný, Marek

      ;

      Klener, Pavel

      2023

      ,

      American Journal of Hematology

      ,

      98

      (10)

      Our knowledge of genetic aberrations, that is, variants and copy number variations (CNVs), associated with mantle cell lymphoma (MCL) relapse remains limited. A cohort of 25 patients with MCL at diagnosis and the first ...

    • Hybrid coatings for orthopaedic implants formed by physical vapour deposition and microarc oxidation 

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      Gabor, R.

      ;

      Cvrček, L.

      ;

      Doubková, Martina

      ;

      Nehasil, Václav

      ;

      Hlinka, J.

      ;

      Unucka, P.

      ;

      Buřil, M.

      ;

      Podepřelová, A.

      ;

      Seidlerová, J.

      ;

      Bačáková, L.

      2022

      ,

      Materials and Design

      ,

      219

      (July)

      This study is focused on the preparation of new hybrid layers intended for surface modification of Ti-6Al-4V alloys for potential orthopaedic and dental applications. Combination of the technology of physical vapour ...

    • Changes on chromosome 11p15.5 as specific marker for embryonal rhabdomyosarcoma? 

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      Vícha, Aleš

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      Jenčová, Pavla

      ;

      Nováková Kodetová, Daniela

      ;

      Štolová, Lucie

      ;

      Voříšková, Dagmar

      ;

      Kodetová, Kristýna

      ;

      Brož, Petr

      ;

      Drahokoupilová, Eva

      ;

      Guha, Anasuya

      ;

      Kopecká, Marie

      ;

      Krsková, Lenka

      2023

      ,

      Genes, Chromosomes & Cancer

      ,

      62

      (12)

      Rhabdomyosarcomas (RMS) constitute a heterogeneous spectrum of tumors with respect to clinical behavior and tumor morphology. The paternal uniparental disomy (pUPD) of 11p15.5 is a molecular change described mainly in ...

    • Health inequalities in post-COVID-19 outcomes among adults aged 50+ in Europe: has COVID-19 exposed divide between postcommunist countries and Western Europe? 

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      Ohno, Maika

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      Dzúrová, Dagmar

      ;

      Smejkal, Petr

      2023

      ,

      Journal of Epidemiology and Community Health

      ,

      77

      (9)

      Background: COVID-19 affected people and countries disproportionately and continues to impact the health of people. The aim is to investigate protective health and socio-geographical factors for post-COVID-19 conditions ...

    • Sborník materiálů z replikace výzkumné studie RN4CAST: Modul Evidence Based Practice ve výuce ošetřovatelské péče 

      Proceedings of the Replication of the RN4CAST Research Study: Evidence Based Practice Module in Nursing Education

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      Zvoníčková, Marie

      ;

      Vojáčková, Anna

      2023

      ,

      Praha

      ,

      Univerzita Karlova, 3. lékařská fakulta, Ústav ošetřovatelství

      Sborník představuje historii tvorby a realizace projektu Modul Evidence based practice ve výuce ošetřovatelské péče v letech 2017-2022. Sborník obsahuje čtyři hlavní okruhy, které byly v pilotním projektu ověřené prakticky ...

    • Epidemiology of Methicillin-Resistant Staphylococcus aureus in Slovakia, 2020 - Emergence of an Epidemic USA300 Clone in Community and Hospitals 

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      Tkadlec, Jan

      ;

      Le, Anh Vu

      ;

      Brajerová, Marie

      ;

      Soltesova, Anna

      ;

      Marcisin, Jozef

      ;

      Dřevínek, Pavel

      ;

      Krůtová, Marcela

      2023

      ,

      Microbiology spectrum

      ,

      11

      (4)

      Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of health care-associated infections. Additionally, over the decades, the spread of community-associated (CA-MRSA) clones has become a serious problem. ...

    • Clostridioides difficile infections were predominantly driven by fluoroquinolone-resistant Clostridioides difficile ribotypes 176 and 001 in Slovakia in 2018-2019
      

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      Plankaova, Adriana

      ;

      Brajerová, Marie

      ;

      Čapek, Václav

      ;

      Novotna, Gabriela Balikova

      ;

      Kinross, Peter

      ;

      Skalova, Jana

      ;

      Soltesova, Anna

      ;

      Dřevínek, Pavel

      ;

      Krůtová, Marcela

      2023

      ,

      International Journal of Antimicrobial Agents

      ,

      62

      (July)

      AIMS: We aimed to investigate Clostridioides difficile (CDI) epidemiology in Slovakian hospitals after the emergence of ribotype 176 (027-like) in 2016. METHODS: Between 2018 and 2019, the ECDC CDI surveillance protocol ...

    • Polysome profiling of oocytes, early development, and cell cycle in mammals 

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      Mašek, Tomáš

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      del Lano, Edgar

      ;

      Sharma, Khushboo

      ;

      Gahurová, Lenka

      ;

      Dvořan, Michal

      ;

      Rajan, Iappan

      ;

      Aleshkina, Daria

      ;

      Končinská, Markéta

      ;

      Bora, Pablo

      ;

      Roučová, Kristina

      ;

      Lin, Chih-Jen

      ;

      Bruce, Alexander William

      ;

      Kubelka, Michal

      ;

      Šušor, Andrej

      ;

      Pospíšek, Martin

      2023

      ,

      Neuvedeno

      ,

      2023

      (Neuvedeno)

      Polysome profiling has provided a gold-standard method to precisely assay functional genome readout at a given time point. The wide-spread utilisation of polysome profiling has nevertheless been historically hindered by ...

    • The H3.3 histone variant and its chaperones in polyomaviral infection 

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      Ryabchenko, Boris

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      Satratzemis, Christos

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2023

      ,

      Praha

      ,

      WBW 2023 Book of Abstracts

      Polyomaviruses (PyVs) are small non-enveloped viruses replicating in the host cell nucleus. Viral replication centers (VRCs) share features with cellular euchromatic or heterochromatic regions, depending on the stage of infection

    • Understanding the role of nuclear lamina during the murine polyomavirus infection using microscopy 

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      Bruštíková, Kateřina

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      Rjabčenko, Boris

      ;

      Huérfano Meneses, Sandra

      ;

      Horníková, Lenka

      2023

      ,

      Montreal

      ,

      DTV2023 The DNATumorVirus Meeting

      The nuclear lamina (NL) is a dense meshwork of intermediate filaments V, type A lamins (lamin A/C), type B lamins (lamin B1 and B2) and membrane associated proteins. NL is located closely adjacent to the nucleoplasmic side ...

    • Pathways to eating disorder care: A European multicenter study 

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      Monteleone, Alessio Maria

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      Barone, Eugenia

      ;

      Cascino, Giammarco

      ;

      Schmidt, Ulrike

      ;

      Gorwood, Philip

      ;

      Volpe, Umberto

      ;

      Abbate-Daga, Giovanni

      ;

      Castellini, Giovanni

      ;

      Marsa, Marina Diaz

      ;

      Favaro, Angela

      ;

      Fukutomi, Akira

      ;

      Guillaume, Sebastien

      ;

      Minařík, Petr

      ;

      Pacheco, Jose Antonio Soriano

      ;

      Panero, Matteo

      ;

      Papežová, Hana

      ;

      Ricca, Valdo

      ;

      Segura-Garcia, Cristina

      ;

      Scanferla, Elisabetta

      ;

      Tyszkiewicz-Nwafor, Marta

      ;

      Fernandez-Aranda, Fernando

      ;

      Voderholzer, Ulrich

      ;

      Treasure, Janet

      ;

      Monteleone, Palmiero

      2023

      ,

      European Psychiatry

      ,

      66

      (1)

      Background: The aim of this study was to assess barriers and facilitators in the pathways toward specialist care for eating disorders (EDs). Methods: Eleven ED services located in seven European countries recruited patients ...

    • One Threat - Multiple Responses: Countering Hybrid Threats in V4 Countries 

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      Procházka, Josef

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      Vinkler, Pavel

      ;

      JÓJÁRT, Krisztián

      ;

      SZENES, Zoltán

      ;

      Gruszczak, Artur

      ;

      Kandrík, Matej

      2023

      ,

      Obrana a strategie

      ,

      23

      (1)

      The new dynamics in the global security environment accompanied by the renewal of greatpower competition and its impact on security provision of Central European countries broughtnew challenges, especially in countering ...

    • Čtení vlastním tempem: Kritické představení metody 

      Self-paced reading: A critical introduction to the method

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      Chromý, Jan

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      Dotlačil, Jakub

      2022

      ,

      Časopis pro moderní filologii

      ,

      104

      (2)

      Self-paced reading has been a widely used experimental method for study of the processing of sentences and texts. In this paper, we introduce the method to the Czech audience. We summarize its advantages and limitations ...

    • The microenvironment of HPV-associated and HPV-negative oropharyngeal tumors 

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      Tachezy, Ruth

      2023

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      Řím

      Patients with HPV-associated oropharyngeal tumors have a survival advantage. They have better treatment response and less frequently develop recurrence. This recognition led to the inclusion of the indirect marker of an ...