Now showing items 321-340 of 1865

    • Association of long-term treatment outcomes with changes in PET/MRI characteristics and the type of early treatment response during concurrent radiochemotherapy in patients with locally advanced cervical cancer 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Vojtíšek, Radovan

      ;

      Baxa, Jan

      ;

      Hošek, Petr

      ;

      Kovářová, Petra

      ;

      Vítovec, Martin

      ;

      Sukovská, Emília

      ;

      Kosťun, Jan

      ;

      Vlasák, Pavel

      ;

      Presl, Jiří

      ;

      Ferda, Jiří

      ;

      Fínek, Jindřich

      2025

      ,

      Urban u. Vogel

      ,

      Strahlentherapie und Onkologie

      ,

      201

      (5)

      PURPOSE: We aimed to find predictive tumour characteristics as detected by interim positron-emission tomography/magnetic resonance imaging (PET/MRI) in cervical cancer patients. We also investigated the type of interim ...

    • Agonistic Spaces: Dissensus and Ethical Conflicts in Recent Irish Theatre 

      chapter in a collective monograph

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Wallace, Clare

      2025

      ,

      Abingdon

      ,

      Routledge, part of the Taylor & Francis Group

      ,

      The Routledge Companion to 21st Century Irish Writing

      This chapter explores agonistic encounters in Irish theatre. Positioning its discussion in relation to the wider Irish theatre context in the first decades of the twenty-first century, the chapter foregrounds three recent ...

    • Genetic Testing for Malformations of Cortical Development 

      original article

      restricted access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Creative Commons NC Icon

      Creative Commons NC Icon

      Straka, Barbora

      ;

      Heřmanovská, Barbora

      ;

      Krsková, Lenka

      ;

      Zámečník, Josef

      ;

      Vlčková, Markéta

      ;

      Balaščaková, Miroslava

      ;

      Tesner, Pavel

      ;

      Jezdik, Petr

      ;

      Tichý, Michal

      ;

      Kynčl, Martin

      ;

      Musilová, Alena

      ;

      Laššuthová, Petra

      ;

      Marusič, Petr

      ;

      Kršek, Pavel

      ;

      Kudr, Martin

      ;

      Bělohlávková, Anežka

      ;

      Ebel, Matyáš

      ;

      Jahodová, Alena

      ;

      Kalinová, Markéta

      ;

      Novak, Vilem

      ;

      Rivera, Gonzalo Alonso Ramos

      ;

      Staněk, David

      ;

      Libý, Petr

      ;

      Kalina, Adam

      ;

      Zárubová, Jana

      ;

      Uhrová Mészárosová, Anna

      ;

      Maulisová, Alice

      ;

      Zůnová, Hana

      ;

      Koblížek, Miroslav

      2022

      ,

      Neurology. Genetics

      ,

      8

      (5)

      Background and Objectives. Malformations of cortical development (MCD), though individually rare, constitute a significant burden of disease. The diagnostic yield of next-generation sequencing (NGS) in these patients varies ...

    • Search for germline gene variants in colorectal cancer families presenting with multiple primary colorectal cancers 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Försti, Asta

      ;

      Ambrożkiewicz, Filip

      ;

      Marciniak, Magdalena

      ;

      Lubinski, Jan

      ;

      Hemminki, Kari Jussi

      2025

      ,

      Wiley-Liss

      ,

      International Journal of Cancer

      ,

      156

      (7)

      A double primary colorectal cancer (CRC) in a familial setting signals a high risk of CRC. In order to identify novel CRC susceptibility genes, we whole-exome sequenced germline DNA from nine persons with a double primary ...

    • Age-specific familial risks in cancer as clues to germline genetic and environmental causes: focus on colorectal, endometrial, prostate, kidney, breast and lung cancers 

      summarizing article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Hemminki, Kari Jussi

      ;

      Försti, Asta

      ;

      Hemminki, Otto

      ;

      Scott, Rodney J

      ;

      Hemminki, Akseli

      2025

      ,

      Termedia

      ,

      Hereditary Cancer in Clinical Practice

      ,

      23

      (1)

      BACKGROUND: The Swedish Family-Cancer Database (FCD) is the largest source of data on familial cancer in the world, including practically complete family structures and individual cancer diagnoses from the high-quality ...

    • Is autism driven by epilepsy in infants with Tuberous Sclerosis Complex? 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Moavero, Romina

      ;

      Kotulska, Katarzyna

      ;

      Lagae, Lieven

      ;

      Benvenuto, Arianna

      ;

      Emberti Gialloreti, Leonardo

      ;

      Weschke, Bernhard

      ;

      Riney, Kate

      ;

      Feucht, Martha

      ;

      Kršek, Pavel

      ;

      Nabbout, Rima

      ;

      Jansen, Anna C

      ;

      Wojdan, Konrad

      ;

      Borkowska, Julita

      ;

      Sadowski, Krzysztof

      ;

      Hertzberg, Christoph

      ;

      Van Schooneveld, Monique M

      ;

      Samueli, Sharon

      ;

      Maulisová, Alice

      ;

      Aronica, Eleonora

      ;

      Kwiatkowski, David J

      ;

      Jansen, Floor E

      ;

      Jozwiak, Sergiusz

      ;

      Curatolo, Paolo

      2020

      ,

      Annals of Clinical and Translational Neurology [online]

      ,

      7

      (8)

      OBJECTIVE: To evaluate the relationship between age at seizure onset and neurodevelopmental outcome at age 24 months in infants with TSC, as well as the effect on neurodevelopmental outcome of early versus conventional ...

    • miRNAs and isomiRs: Serum-Based Biomarkers for the Development of Intellectual Disability and Autism Spectrum Disorder in Tuberous Sclerosis Complex 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Scheper, Mirte

      ;

      Romagnolo, Alessia

      ;

      Besharat, Zein Mersini

      ;

      Iyer, Anand M

      ;

      Moavero, Romina

      ;

      Hertzberg, Christoph

      ;

      Weschke, Bernhard

      ;

      Riney, Kate

      ;

      Feucht, Martha

      ;

      Scholl, Theresa

      ;

      Petrák, Bořivoj

      ;

      Maulisová, Alice

      ;

      Nabbout, Rima

      ;

      Jansen, Anna C

      ;

      Jansen, Floor E

      ;

      Lagae, Lieven

      ;

      Urbanska, Malgorzata

      ;

      Ferretti, Elisabetta

      ;

      Tempes, Aleksandra

      ;

      Blazejczyk, Magdalena

      ;

      Jaworski, Jacek

      ;

      Kwiatkowski, David J

      ;

      Jozwiak, Sergiusz

      ;

      Kotulska, Katarzyna

      ;

      Sadowski, Krzysztof

      ;

      Borkowska, Julita

      ;

      Curatolo, Paolo

      ;

      Mills, James D

      ;

      Aronica, Eleonora

      2022

      ,

      Biomedicines [online]

      ,

      10

      (8)

      Tuberous sclerosis complex (TSC) is a rare multi-system genetic disorder characterized by a high incidence of epilepsy and neuropsychiatric manifestations known as tuberous-sclerosis-associated neuropsychiatric disorders ...

    • Meeting summary of The NYO3 5th NO-Age/AD meeting and the 1st Norway-UK joint meeting on ageing and dementia: recent progress on the mechanisms and interventional strategies 

      original article

      restricted access

      accepted version

      Creative Commons License Icon

      Creative Commons BY Icon

      Wang, He-Ling

      ;

      Siow, Richard

      ;

      Schmauck-Medina, Tomas

      ;

      Zhang, Jianying

      ;

      Sandset, Per Morten

      ;

      Filshie, Clare

      ;

      Lund, Øystein

      ;

      Partridge, Linda

      ;

      Bergersen, Linda Hildegard

      ;

      Juel Rasmussen, Lene

      ;

      Palikaras, Konstantinos

      ;

      Sotiropoulos, Ioannis

      ;

      Storm-Mathisen, Jon

      ;

      Rubinsztein, David C

      ;

      Spillantini, Maria Grazia

      ;

      De Zeeuw, Chris I

      ;

      Watne, Leiv Otto

      ;

      Vyhnálek, Martin

      ;

      Veverová, Kateřina

      ;

      Liang, Kristina Xiao

      ;

      Tavernarakis, Nektarios

      ;

      Bohr, Vilhelm A

      ;

      Yokote, Koutaro

      ;

      Saarela, Janna

      ;

      Nilsen, Hilde

      ;

      Gonos, Efstathios S

      ;

      Scheibye-Knudsen, Morten

      ;

      Chen, Guobing

      ;

      Kato, Hisaya

      ;

      Selbæk, Geir

      ;

      Fladby, Tormod

      ;

      Nilsson, Per

      ;

      Simonsen, Anne

      ;

      Aarsland, Dag

      ;

      Lautrup, Sofie

      ;

      Ottersen, Ole Petter

      ;

      Cox, Lynne S

      ;

      Fang, Evandro F

      2024

      ,

      Journals of Gerontology - Series A Biological Sciences and Medical Sciences

      ,

      79

      (4)

      Unhealthy ageing poses a global challenge with profound healthcare and socioeconomic implications. Slowing down the ageing process offers a promising approach to reduce the burden of a number of age-related diseases, such ...

    • Environmental aspects of wastewater recycling from the point of view of emergent pollutant removal 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Šereš, Michal

      ;

      Černá, Tereza

      ;

      Hnátková, Tereza

      ;

      Rozkošný, Miloš

      ;

      Grasserová, Alena

      ;

      Semerád, Jaroslav

      ;

      Němcová, Kateřina

      ;

      Cajthaml, Tomáš

      2025

      ,

      IWA Publishing

      ,

      Water Science and Technology

      ,

      91

      (7)

      This study evaluates the removal efficiency of 15 estrogenic endocrine-disrupting compounds in two operational constructed wetlands with different designs: a hybrid system (constructed wetland A) and a horizontal system ...

    • Does VS30 reflect seismic amplification? Observations from the West Bohemia Seismic Network 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Mazanec, Martin

      ;

      Valenta, Jan

      ;

      Málek, Jiří

      2024

      ,

      Kluwer

      ,

      Natural Hazards

      ,

      120

      (13)

      The present study addresses verification of average seismic shear-wave velocity from the surface to a depth of 30 m (V(S30)) as a suitable proxy for a seismic amplification. For this purpose, we used instrumentally homogeneous ...

    • Exploring Virulence Characteristics of Clinical Escherichia coli Isolates from Greece 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Gagaletsios, Lazaros A.

      ;

      Kikidou, Elisavet

      ;

      Galbenis, Christos

      ;

      Bitar, Ibrahim

      ;

      Papagiannitsis, Costas C.

      2025

      ,

      MDPI

      ,

      Microorganisms

      ,

      13

      (7)

      The aim of this study was to examine the genetic characteristics that could be associated with the virulence characteristics of Escherichia coli collected from clinical samples. A collection of 100 non-repetitive E. coli ...

    • Comparative genomics of multi-drug resistant Escherichia coli ST131 from human, animal, and environmental sources in the Czech Republic 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Růžičková, Michaela

      ;

      Karola, Ivana

      ;

      Nohejl, Tomas

      ;

      Sukkar, Iva

      ;

      Palkovičová, Jana

      ;

      Papousek, Ivo

      ;

      Cummins, Max L.

      ;

      Djordjevic, Steven P.

      ;

      Dolejská, Monika

      2025

      ,

      Ecotoxicology and Environmental Safety

      ,

      299

      (July)

      Globally, Escherichia coli is a leading cause of multiple drug-resistant (MDR) extraintestinal infections. ST131 is an MDR, pandemic sequence type that causes urinary tract and bloodstream infections in humans and companion ...

    • The Pattern and the Image in Plotinus: Rethinking Plato’s Conflict with the Poets 

      chapter in a collective monograph

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Gál, Ota

      2025

      ,

      Berlin

      ,

      De Gruyter

      ,

      The Pattern and the Image: Insights from the Alexandrian Exegetical Tradition

      This paper presents parallels between Plato's and Plotinus' understanding of the notion of an image within the context of the arts and cosmology. It argues for the rejection of the widespread cliché according to which ...

    • Not-so-Failing Junior Partner: Re-examining the AEF's Chemical Warfare Experience before and during the German Spring Offensives 

      original article

      restricted access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Creative Commons NC Icon

      Klepárník, Vít

      2025

      ,

      SAGE

      ,

      War in History

      ,

      32

      (1)

      This study, using the revisionist critique of the American Expeditionary Forces (AEF), reopens the issue of US involvement in the ever-engaging field of World War I chemical warfare. It disputes revisionist claims of a ...

    • Fault Gouge Failure Induced by Fluid Injection: Hysteresis, Delay and Shear-Strengthening 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Creative Commons NC Icon

      Sarma, Pritom

      ;

      Aharonov, Einat

      ;

      Toussaint, Renaud

      ;

      Pařez, Stanislav

      2025

      ,

      Journal of Geophysical Research: Solid Earth

      ,

      130

      (6)

      Natural faults often contain a fluid-saturated, granular fault-gouge layer, whose failure and sliding processes play a central role in earthquake dynamics. Using a two-dimensional discrete element model coupled with fluid ...

    • In-Situ Vp/Vs ratio variations in seismic swarms as indicator of magmatic processes: Fagradalsfjall volcanic activity, SW Iceland 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Masihi, Ali

      ;

      Fischer, Tomáš

      2025

      ,

      Geophysical Journal International

      ,

      241

      (3)

      In this study, we applied the 'in-situ Vp/Vs method' to monitor variations of seismic velocity ratio (Vp/Vs) within swarms, providing insights into eruption processes. This method, particularly effective in volcanic regions, ...

    • Navajo Sandstone concretions record extended magnetic chronology 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Creative Commons NC Icon

      Creative Commons NC Icon

      Smrčinová, Lucie

      ;

      Kletetschka, Günther

      2025

      ,

      Springer Nature

      ,

      Scientific Reports

      ,

      15

      (1)

      The study investigates iron oxide concretions from the Jurassic Navajo Sandstone in Utah to assess their potential as long-term paleomagnetic recorders. Using alternating field and thermal demagnetization, chemical analysis, ...

    • EDENT1FI Master Protocol for screening of presymptomatic early-stage type 1 diabetes in children and adolescents 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Hoffmann, Luisa

      ;

      Kohls, Mirjam

      ;

      Arnolds, Stefanie

      ;

      Achenbach, Peter

      ;

      Bergholdt, Regine

      ;

      Bonifacio, Ezio

      ;

      Bosi, Emanuele

      ;

      Gündert, Melanie

      ;

      Hoefelschweiger, Bianca K

      ;

      Hummel, Sandra

      ;

      Jarosz-Chobot, Przemysława

      ;

      Kordonouri, Olga

      ;

      Lampasona, Vito

      ;

      Narendran, Parth

      ;

      Overbergh, Lut

      ;

      Pociot, Flemming

      ;

      Raposo, João Filipe

      ;

      Šumník, Zdeněk

      ;

      Szypowska, Agnieszka

      ;

      Vercauteren, Jurgen

      ;

      Winkler, Christiane

      ;

      Mathieu, Chantal

      ;

      Ziegler, Anette-Gabriele

      2025

      ,

      BMJ Publishing Ltd.

      ,

      BMJ Open

      ,

      15

      (1)

      INTRODUCTION: The identification of type 1 diabetes at an early presymptomatic stage has clinical benefits. These include a reduced risk of diabetic ketoacidosis (DKA) at the clinical manifestation of the disease and a ...

    • Genome integration of human DNA oncoviruses 

      summarizing article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Vojtěchová, Zuzana

      ;

      Tachezy, Ruth

      2025

      ,

      Journal of Virology

      ,

      99

      (8)

      Tumors of infectious origin globally represent 13%. Oncogenic DNA viruses such as human papillomavirus (HPV), hepatitis B virus (HBV), and Epstein-Barr virus (EBV) are responsible for approximately 60% of these tumors. ...

    • Exploring Teachers’ Resource Utilization Practices and Beliefs in Mathematics Education: A Cross-National Study on Reasoning and Proving 

      original article

      open access

      published version

      Creative Commons License Icon

      Creative Commons BY Icon

      Kohanová, Iveta

      ;

      Slavíčková, Mária

      ;

      Rosa, Samuel

      ;

      Di Paola, Benedetto

      ;

      Michal, Jakub

      ;

      Çakıroğlu, Çakıroğlu

      2025

      ,

      International Journal of Science and Mathematics Education

      ,

      Neuveden

      (April)

      This study delves into resource utilization for teaching reasoning and proof (R&P) among mathematics teachers across five European countries. Employing an online questionnaire, the research gathers data on resource use, ...