Repozitář publikační činnosti UK: Poslední příspěvky
Zobrazují se záznamy 801-820 z 1813
-
Defects in B-lymphopoiesis and B-cell maturation underlie prolonged B-cell depletion in ANCA-associated vasculitis
původní článek
open access
vydavatelská verze
2024
,Annals of the Rheumatic Diseases
,83
(11)
OBJECTIVES: B-cell depletion time after rituximab (RTX) treatment is prolonged in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) compared with other autoimmune diseases. We investigated central and ...
-
Tviblindi algorithm identifies branching developmental trajectories of human B-cell development and describes abnormalities in RAG-1 and WAS patients
původní článek
open access
vydavatelská verze
2024
,European Journal of Immunology
,54
(12)
Detailed knowledge of human B-cell development is crucial for the proper interpretation of inborn errors of immunity and malignant diseases. It is of interest to understand the kinetics of protein expression changes during ...
-
Giant Cell Temporal Arteritis Followed by Severe Encephalopathy Induced by Immunotherapy in a Patient with Metastatic Renal Cell Carcinoma Achieving Durable Partial Response: A Case Report
kazuistika
open access
vydavatelská verze
2024
,Case Reports in Oncology
,17
(1)
Introduction: Combined immuno-oncology (IO) regimens are the cornerstone of the current front-line systemic therapy for metastatic renal cell carcinoma (mRCC). Despite the fact that combined IO regimens show high efficacy, ...
-
Steady survival improvements in soft tissue and bone sarcoma in the Nordic countries through 50 years
původní článek
open access
vydavatelská verze
2024
,Cancer Epidemiology
,29
(October)
Purpose: Sarcomas are rare cancers with many subtypes in soft tissues, bone and cartilage. International survival trends in these cancers are not well known. We present 50-year survival trends for soft tissue sarcoma (STS) ...
-
Adenotonsillar pathology in mucopolysaccharidoses - lysosomal storage predominates in paracortical CD63+ cells
původní článek
open access
vydavatelská verze
2024
,Springer
,Virchows Archiv
,484
(1)
Despite the adenoids are regularly removed in patients with mucopolysaccharidoses (MPS), the underlying tissue and cellular pathologies remain understudied. We characterized an (immuno)histopathologic and ultrastructural ...
-
A Fast HPLC/UV Method for Determination of Ketoprofen in Cellular Media
původní článek
open access
vydavatelská verze
2024
,Wiley - V C H Verlag GmbH & Co. KGaA
,ChemistryOpen
,13
(3)
A simple, sensitive and quick HPLC method was developed for the determination of ketoprofen in cell culture media (EMEM, DMEM, RPMI). Separation was performed using a gradient on the C18 column with a mobile phase of ...
-
LysoGb3 quantification facilitates phenotypic categorization of Fabry disease patients: Insights gained by a novel MS/MS method
původní článek
open access
vydavatelská verze
2024
,Elsevier BV
,Clinica Chimica Acta
,561
(July)
Background: Fabry disease (FD) is an X-linked lysosomal storage disease resulting from pathogenic variants in the GLA gene coding alpha-galactosidase A (AGAL) and cleaving terminal alpha-linked galactose. Globotriaosylceramide ...
-
Changes of Anaerobic Power and Lactate Concentration following Intense Glycolytic Efforts in Elite and Sub-Elite 400-meter Sprinters
původní článek
open access
vydavatelská verze
2024
,Journal of Human Kinetics
,91
(April Spec Issue)
400-m races are based on anaerobic energy metabolism, they induce significant muscle fatigue, muscle fiber damage, and high blood lactate (LA) concentration. Despite extensive research on sprint training, our understanding ...
-
The Czech National MS Registry (ReMuS): Data trends in multiple sclerosis patients whose first disease-modifying therapies were initiated from 2013 to 2021
původní článek
open access
vydavatelská verze
2024
,Palacký University
,Biomedical Papers
,168
(3)
AIMS: Multiple sclerosis treatment strategies are changing in the Czech Republic. According to data from 2013-2021, the proportion of patients starting high-efficacy disease-modifying therapies is increasing. In this survey, ...
-
Structural and microstructural predictors of cognitive decline in deep brain stimulation of subthalamic nucleus in Parkinson's disease
původní článek
open access
vydavatelská verze
2024
,Elsevier
,NeuroImage. Clinical
,42
(May)
BACKGROUND AND OBJECTIVES: The intricate relationship between deep brain stimulation (DBS) in Parkinson's disease (PD) and cognitive impairment has lately garnered substantial attention. The presented study evaluated pre-DBS ...
-
Naturalizing Nous ? Theophrastus on Nous, Nature, and Motion
původní článek
open access
vydavatelská verze
2024
,Phronesis
,69
(4)
There is prima facie evidence that Theophrastus naturalized nous to the extent that he spoke of it in naturalizing terms. But our evidence also suggests that Theophrastus accepted the reasons Aristotle had for excluding ...
-
Amiodarone but not propafenone impairs bioenergetics and autophagy of human myocardial cells
původní článek
open access
vydavatelská verze
2023
,Toxicology and Applied Pharmacology
,477
(October)
Cardiac and extra-cardiac side effects of common antiarrhythmic agents might be related to drug-induced mitochondrial dysfunction. Supratherapeutic doses of amiodarone have been shown to impair mitochondria in animal ...
-
Small nucleolar RNA expression profiles: A potential prognostic biomarker for non-viral Hepatocellular carcinoma
původní článek
open access
vydavatelská verze
2024
,Non-coding RNA Research
,9
(4)
Hepatocellular carcinoma (HCC) is a challenging cancer with high mortality rates, limited predictability, and a lack of effective prognostic indicators. The relationship between small nucleolar RNAs (snoRNAs) and HCC is ...
-
Restituce nacisty uloupeného umění v České republice
Restitution of Nazi-Looted Art in the Czech Republic
přednáška
open access
draft
2024
Podobně jako sousední země je i Česká republika zasažena problematikou nacisty uloupeného umění. Nicméně vzhledem ke specifickélokální situaci musela najít vhodný způsob, jak se s touto problematikou vypořádat. První ...
-
The Struggle for Justice: Post-WWII Restitution of Richard Morawetz’ Art Collection
přednáška
embargo
draft
2024
This presentation shows the post-WWII restitution efforts for the significant art collection of Richard Morawetz, which was deposited in the the National Gallery Prague in 1939. Following the family's escape from Czechoslovakia ...
-
Analýza judikatury Nejvyššího správního soudu týkající se požadavků na odůvodnění opatření podle tzv. pandemického zákona
Analysis of the case law of the Czech Supreme Administrative Court concerning the requirements for the explanatory memoranda of measures adopted under the so-called Pandemic Act
původní článek
open access
vydavatelská verze
2024
,Acta Universitatis Carolinae. Iuridica
,70
(3)
Článek reflektuje požadavky na odůvodnění mimořádných opatření přijatých podle zákona č. 94/2001 Sb. (tzv. pandemického zákona), které plynou z judikatury Nejvyššího správního soudu. Vedle požadavků na odůvodnění mimořádných ...
-
Comparative Study on Refunds Stipulated in the Budgetary Discipline Enforcement Regulatory Framework in the Visegrád Countries
původní článek
open access
vydavatelská verze
2024
,The Lawyer Quarterly
,14
(3)
Refunds play a crucial role in enforcing budgetary discipline across regulatory frameworks, ensuring that public funds remain aligned with their intended purposes. This article aims to explore the similarities and differences ...
-
(Ne)důvěra v očkování v ČR pohledem zdravotníků a váhavých rodičů
(Dis)trust in vaccination in the Czech Republic from the perspective of health professionals and hesitant parents
původní článek
open access
vydavatelská verze
2024
,Vox Pediatriae
,24
(2)
Váhavost k očkování je multidimenzionální fenomén, který je ovlivňován řadou individuálních i společenských faktorů (např. Dubé et al., 2013; MacDonald, 2015). Individuální faktory (např. Dubé et al., 2013; Rey et al., ...
-
Critical survival periods in prostate cancer in Sweden explored by conditional survival analysis
původní článek
open access
vydavatelská verze
2024
,Cancer Medicine
,13
(7)
BackroundWe wanted to characterize conditional survival in prostate cancer (PC) in Sweden around and after 2005 when the vast increase in incidence due to the opportunistic testing for prostate specific antigen (PSA) ...
-
A metric for comparison and visualization of age disparities in cancer survival
původní článek
omezený přístup
vydavatelská verze
2024
,Cancer Epidemiology
,91
(August)
AIMS: Diagnostic age is an important determinant of cancer survival but the methods generally used to analyze age-group-specific survival are not developed for ready visualization of survival differences. We aim at developing ...
