Repozitář publikační činnosti UK: Poslední příspěvky

Zobrazují se záznamy 781-800 z 1813

    • ASPH inhibition reveals differential gene expression patterns in HPV-positive and HPV-negative cell lines 

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      Kanwal, Madiha

      ;

      Kasi, Murtaza Khan

      ;

      Šmahelová, Jana

      ;

      Olsen, Mark

      ;

      Tachezy, Ruth

      ;

      Šmahel, Michal

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Cancer is associated with alterations in key cellular pathways, including the aspartate ββ-hydroxylase (ASPH) pathway, an oncogene upregulated in various carcinomas that plays a crucial role in tumor progression and ...

    • The biomolecular markers for the personalized prediction of the treatment effect in patients with head and neck cancer: Pilot study 

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      Vojtěchová, Zuzana

      ;

      Milt, Petr

      ;

      Saláková, Martina

      ;

      Šmahelová, Jana

      ;

      Lohynská, Radka

      ;

      Lacek, Michal

      ;

      Čoček, Aleš

      ;

      Krátká, Zuzana

      ;

      Tachezy, Ruth

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      The clinical utility of liquid biopsies as diagnostic, predictive and prognostic biomarkers has been shown for several cancers. Our study analyses the dynamics of human papillomavirus (HPV) cell cell-free DNA (cfDNA) levels ...

    • Effect of the ADAR1 signalling pathway on HCV replication 

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      Kubů, Martin

      ;

      Roučová, Kristina

      ;

      Pospíšek, Martin

      ;

      Vopálenský, Václav

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      The hepatitis C virus (HCV) is a member of the Flaviviridae family, the genome of which consists of a +RNA molecule. It causes hepatitis C, which infects tens of millions of people worldwide. Although new direct direct-acting ...

    • Unveiling viral diversity through wholevirome sequencing 

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      Saláková, Martina

      ;

      Kadlečková, Dominika

      ;

      Šimić, Ivana

      ;

      Tachezy, Ruth

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      In the dynamic landscape of viral metagenomics, our research focuses on whole-virome sequencing using the Novel enrichment technique of viromes protocol (NetoVir protocol, 1), which we have adapted to diverse starting ...

    • Understanding the interplay between BK polyomavirus and celular restriction factors 

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      Lovtsov, Alexey

      ;

      Rjabčenko, Boris

      ;

      Janovec, Václav

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      The most important human polyomavirus are the Merkel cell polyomavirus, the etiological agent of 80% of Merkel cell carcinoma, JCPyV that causes progressive multifocal leukoencephalopathy and BKPyV which causes nephropathy. ...

    • miRNA146a is a key component of immunnosupressive environment of hepatocytes chronically infected with HBV 

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      Berehovska, Olena

      ;

      Pimková Polidarová, Markéta

      ;

      Janovec, Václav

      ;

      Hirsch, Ivan

      ;

      Grantz Šašková, Klára

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Hepatitis B virus (HBV) causes acute hepatitis and can lead to chronic liver inflammation, often resulting in hepatocellular carcinoma. Known as a stealth virus, virus," HBV can evade recognition by the immune system. ...

    • Investigation of BKPyV life cycle, activation of innate immune responses and membrane remodeling in microvascular endothelial cells 

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      Bruštíková, Kateřina

      ;

      Rjabčenko, Boris

      ;

      Liebl, David

      ;

      Horníková, Lenka

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Polyomaviruses (PyVs) are small double-stranded DNA viruses that occur widely in nature. Among the 14 known human PyVs, three are particularly relevant: BK Polyomavirus (BKPyV), JC polyomavirus, and Merkel cell carcinoma ...

    • Relationship between yeast virus like elements and poxviruses at the transcriptional level 

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      Vopálenský, Václav

      ;

      Sýkora, Michal

      ;

      Mělková, Zora

      ;

      Barvík, Ivan

      ;

      Mašek, Tomáš

      ;

      Horáčková, Kamila

      ;

      Pospíšek, Martin

      2024

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Yeast cytoplasmic double-stranded DNA virus-like elements (VLEs, also known as linear plasmids) were found in a number of yeast species belonging to nine genera. The Kluyveromyces lactis pGKL1/2 plasmids, which serve as ...

    • Interactome analysis of the mouse polyomavirus large T antigen 

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      Štaflová, Karolína

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      Šroller, Vojtěch

      ;

      Pichová, Iva

      ;

      Bártová, Jana

      ;

      Rjabčenko, Boris

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2024

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Polyomaviruses are small nonenveloped viruses that replicate in the nucleus of the host cell. The mouse polyomavirus (MPyV) large T antigen (LT) is the multifunctional protein expressed in the early phase of the viral ...

    • Small-molecule activators of NRF1 transcriptional activity prevent protein aggregaton 

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      Sedláček, Jindřich

      ;

      Šmahelová, Zuzana

      ;

      Adámek, Michael

      ;

      Šubová, Dominika

      ;

      Majer, Pavel

      ;

      Svobodová, Lucie

      ;

      Kadlecová, Alena

      ;

      Petrezsélyová, Silvia

      ;

      Machara, Aleš

      ;

      Grantz Šašková, Klára

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Intracellular protein aggregation causes proteotoxic stress, underlying highly debilitating neurodegenerative disorders in parallel with decreased proteasome activity.Nevertheless, under such stress conditions, the expression ...

    • Novel autophagy inducer inhibits hepatitis B virus S antigen secretion 

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      Šmahelová, Zuzana

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      Pimková Polidarová, Markéta

      ;

      Sedláček, Jindřich

      ;

      Berehovska, Olena

      ;

      Janovec, Václav

      ;

      Adámek, Michael

      ;

      Hirsch, Ivan

      ;

      Machara, Aleš

      ;

      Grantz Šašková, Klára

      2024

      ,

      Česká společnost chemická

      ,

      Czech Chemical Society Symposium Series

      ,

      22

      (6)

      Chronic hepatitis B (CHB), a liver infection caused by the hepatitis B virus (HBV), affects more than 300 million people worldwide. If left untreated, CHB can progress to liver cirrhosis and hepatocellular carcinoma, ...

    • Parental views on their children’s smartphone use during personal and relational activities 

      původní článek

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      vydavatelská verze

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      Lukavská, Kateřina

      ;

      Gabrhelík, Roman

      2024

      ,

      Public Library of Science

      ,

      PLoS One

      ,

      19

      (8)

      Given the negative outcomes associated with smartphone use during personal and relational activities (SUPRA), parents strive to regulate its use among their children. However, media parenting recommendations lack knowledge ...

    • DDI2 protease controls embryonic development and inflammation via TCF11/NRF1 

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      Nedomová, Monika

      ;

      Haberecht-Müller, Stefanie

      ;

      Möller, Sophie

      ;

      Venz, Simone

      ;

      Procházková, Michaela

      ;

      Procházka, Jan

      ;

      Sedlák, František

      ;

      Chawengsaksophak, Kallayanee

      ;

      Hammer, Elke

      ;

      Kašpárek, Petr

      ;

      Adámek, Michael

      ;

      Sedláček, Radislav

      ;

      Konvalinka, Jan

      ;

      Elke, Kruger

      ;

      Grantz Šašková, Klára

      2024

      ,

      Cell Press, Elsevier, Inc.

      ,

      iScience

      ,

      27

      (10)

      DDI2 is an aspartic protease that cleaves polyubiquitinated substrates. Upon proteotoxic stress, DDI2 activates the transcription factor TCF11/NRF1 (NFE2L1), crucial for maintaining proteostasis in mammalian cells, enabling ...

    • Positive Effect of a Cooling Cap on Functional Performance in Thermosensitive People with Multiple Sclerosis: A Randomized Controlled Trial 

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      Novotná, Klára

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      Dedinova, K.

      ;

      Meňkyová, Ingrid

      ;

      Uher, Tomáš

      ;

      Kubala Havrdová, Eva

      ;

      Angerová, Yvona

      2024

      ,

      Munksgaard

      ,

      Acta Neurologica Scandinavica

      ,

      2024

      (April)

      Background. Up to 80% of people with MS experience worsening of their condition upon an increase in body temperature. Therefore, various options of cooling are being evaluated to help improve physical performance in people ...

    • School choice and parenting strategies among Czech middle‐class parents : Implications for social segregation in public schools 

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      Smith Slámová, Radka

      ;

      Simonová, Jaroslava

      2024

      ,

      Sociology Compass

      ,

      e13248

      (23.7.2024)

      Research examining middle-class parents' school choices often overlooks parents in post-socialist nations, where social reproduction may occur differently than in Western urban contexts. To bridge this gap, our study ...

    • Why do teachers leave schools? Evidence from lower secondary schools in the Czech Republic 

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      vydavatelská verze

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      Straková, Jana

      ;

      Simonová, Jaroslava

      2024

      ,

      International Journal of Educational Management

      ,

      neuveden

      (18.2.2024)

      Purpose - This study aims to supplement the international knowledge on factors determining retention in theteaching profession with findings from the Czech Republic. The study aims to answer the question of whatfactors on ...

    • Proteogenomic Characterization of Pseudomonas veronii SM-20 Growing on Phenanthrene as Only Carbon and Energy Source 

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      Zavala Meneses, Sofia Guadalupe

      ;

      Firrincieli, Andrea

      ;

      Chalova, Petra

      ;

      Pajer, Petr

      ;

      Checcucci, Alice

      ;

      Škultéty, Ľudovít

      ;

      Cappelletti, Martina

      2024

      ,

      Microorganisms

      ,

      12

      (4)

      In this study, we conducted an extensive investigation of the biodegradation capabilities and stress response of the newly isolated strain Pseudomonas veronii SM-20 in order, to assess its potential for bioremediation of ...

    • More Than Meets the Reply: Examining Emotional Belonging in Far-Right Social Media Space 

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      omezený přístup

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      Collins, Jonathan

      2024

      ,

      Social media + Society

      ,

      10

      (3)

      This article challenges prevailing assumptions that fringe social media platforms predominantly serve as unmoderated hate-filled spaces for far-right communication by examining the userbase's emotional connection to these ...

    • The effect of aspartate β-hydroxylase inhibition on cancer immunotherapy 

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      Johari, Shweta Dilip

      ;

      Krausová, Kateřina

      ;

      Žucha, Barbora

      ;

      Madureira Trufen, Carlos Eduardo

      ;

      Poláková, Ingrid

      ;

      Olsen, Mark

      ;

      Šmahel, Michal

      2024

      ,

      Neuveden

      Aspartate β-hydroxylase (ASPH) is overexpressed in 70-90% of various solid tumors, contributing to tumor cell proliferation, migration, and invasion. In addition, recombinant ASPH inhibits natural killer (NK) cells, but ...

    • Self-administered mindfulness interventions reduce stress in a large, randomized controlled multi-site study 

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      Sparacio, Alessandro

      ;

      IJzerman, Hans

      ;

      Ropovik, Ivan

      ;

      Giorgini, Filippo

      ;

      Spiessens, Christoph

      ;

      Uchino, Bert N.

      ;

      Landvatter, Joshua

      ;

      Tacana, Tracey

      ;

      Diller, Sandra J.

      ;

      Derrick, Jaye L.

      ;

      Segundo, Joahana

      ;

      Pierce, Jace D.

      ;

      Ross, Robert M.

      ;

      Francis, Zoë

      ;

      LaBoucane, Amanda

      ;

      Ma-Kellams, Christine

      ;

      Ford, Maire B.

      ;

      Schmidt, Kathleen

      ;

      Wong, Celia C.

      ;

      Higgins, Wendy C.

      ;

      Stone, Bryant M.

      ;

      Stanley, Samantha K.

      ;

      Ribeiro, Gianni

      ;

      Fuglestad, Paul T.

      ;

      Jaklin, Valerie

      ;

      Kübler, Andrea

      ;

      Ziebell, Philipp

      ;

      Jewell, Crystal L.

      ;

      Kovas, Yulia

      ;

      Allahghadri, Mahnoosh

      ;

      Fransham, Charlotte

      ;

      Baranski, Michael F.

      ;

      Burgess, Hannah

      ;

      Benz, Annika B.E.

      ;

      DeSousa, Maysa

      ;

      Nylin, Catherine E.

      ;

      Brooks, Janae C.

      ;

      Goldsmith, Caitlyn M.

      ;

      Benson, Jessica M.

      ;

      Griffin, Siobhán M.

      ;

      Dunne, Stephen

      ;

      Davis, William E.

      ;

      Watermeyer, Tam J.

      ;

      Meese, William B.

      ;

      Howell, Jennifer L.

      ;

      Standiford Reyes, Laurel

      ;

      Strickland, Megan G.

      ;

      Dickerson, Sally S.

      ;

      Pescatore, Samantha

      ;

      Skakoon-Sparling, Shayna

      ;

      Wunder, Zachary I.

      ;

      Day, Martin V.

      ;

      Brenton, Shawna

      ;

      Linden, Audrey H.

      ;

      Hawk, Christopher E.

      ;

      O’Brien, Léan V.

      ;

      Urgyen, Tenzin

      ;

      McDonald, Jennifer S.

      ;

      van der Schans, Kim Lien

      ;

      Blocker, Heidi

      ;

      Ng Tseung-Wong, Caroline

      ;

      Jiga-Boy, Gabriela M.

      2024

      ,

      Nature Human Behaviour

      ,

      8

      (11.6.2024)

      Mindfulness witnessed a substantial popularity surge in the past decade, especially as digitally self-administered interventions became available at relatively low costs. Yet, it is uncertain whether they effectively help ...