We studied the impact of JAK2 fusions on metabolic rewiring of leukemic cells; we chose two representatives, themost frequent fusion and a novel previously undescribed fusion, and we showed that JAK2 fusions indeed alter ...
Our knowledge of genetic aberrations, that is, variants and copy number variations (CNVs), associated with mantle cell lymphoma (MCL) relapse remains limited. A cohort of 25 patients with MCL at diagnosis and the first ...
Background Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placental ...
This Critical Exchange suggests that Schmittian inspirations abound in countries that experience democratic backsliding. Sometimes, Schmitt's ideas are used explicitly, but more often they are implicit in the actions of ...
BK virus (BKPyV) is a causative agent of BKPyV-associated nephropathy and graft rejections in kidney transplant patients. It establishes persistent infection in the kidneys, which can lead to reactivation in an immunosuppressed ...
MT1-MMP (MMP-14) is a multifunctional protease that regulates ECM degradation, activation of other proteases, and a variety of cellular processes, including migration and viability in physiological and pathological contexts. ...
In our study, the effect of the use of autofluorescence (Visually Enhanced Lesion Scope-VELscope) on increasing the success rate of surgical treatment in oral squamous carcinoma (OSCC) was investigated. Our hypothesis was ...
Oxysterols, oxidized derivatives of cholesterol, act in breast cancer (BC) as selective estrogen receptor modulators and affect cholesterol homeostasis, drug transport, nuclear and cell receptors, and other signaling ...
Exercise order is one of the significant factors modulating training effects. Therefore, the aim of this study was to compare the effectiveness of an 8-week complex (CPX) training program utilizing intra-CPX active recovery ...
TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene expression. Dysregulation of their activity is associated with many serious pathogenic states such as oncological diseases. ...