Influence of the microenvironment of hepatitis B virus-infected hepatocytes on innate immunity's mechanisms

abstract in conference proceedings
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Author
Berehovska, Olena
Pimková Polidarová, MarkétaORCiD Profile - 0000-0003-3116-1328WoS Profile - V-2351-2017Scopus Profile - 57212310198
Janovec, VáclavORCiD Profile - 0000-0002-6262-3364WoS Profile - N-7608-2017Scopus Profile - 57193086112
Grantz Šašková, KláraORCiD Profile - 0000-0003-2874-5699WoS Profile - E-1931-2014Scopus Profile - 22954587000
Hirsch, IvanORCiD Profile - 0000-0003-1701-1438WoS Profile - R-3103-2016Scopus Profile - 56275056800
Jurášek, Michal
Řápková, Radmila
Benešová, Eva
Drašar, Pavel
Czech Chemical Society,Czech Society for Biochemistry and Molecular Biology

Publication date
2023
Published in
XXIInd Interdisciplinary Meeting of Young Life Scientists
Publisher / Publication place
Česká společnost chemická (Praha)
Volume / Issue
21 (2)
ISBN / ISSN
ISSN: 2336-7202
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Abstract
HBV virus is an infectious agent that replicates in the hepatocytes and causes an acute form of hepatitis, but it can also lead to a chronical inflammation, and consequently, to a hepatocellular carcinoma. HBV virus is also described as "stealth virus" due to its ability to avoid recognition by the innate immunity system and the immune activation, as it does not cause the immune response1.The goal of our project is to discover the immune inhibitory mechanism, as this knowledge can be useful in clinical research.
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https://hdl.handle.net/20.500.14178/1914
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