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Dear users, welcome to the new interface of the Charles University Publication Repository. We would appreciate it if you could take a moment of your time to provide us with feedback on the new design of the repository.
Dotazník pro zpětnou vazbu je dostupný na URL adrese / The feedback questionnaire is available at the URL address: https://forms.office.com/e/ueBL8SYPZt
Clinical Experience with Autofluorescence Guided Oral Squamous Cell Carcinoma Surgery
dc.contributor.author | Pošta, Petr | |
dc.contributor.author | Kolk, Andreas | |
dc.contributor.author | Pivovarčíková, Kristýna | |
dc.contributor.author | Liška, Jan | |
dc.contributor.author | Genčur, Jiří | |
dc.contributor.author | Moztarzadeh, Omid | |
dc.contributor.author | Micopulos, Christos | |
dc.contributor.author | Pěnkava, Adam | |
dc.contributor.author | Frolo, Mária | |
dc.contributor.author | Bissinger, Oliver | |
dc.contributor.author | Hauer, Lukáš | |
dc.date.accessioned | 2023-10-18T12:40:28Z | |
dc.date.available | 2023-10-18T12:40:28Z | |
dc.date.issued | 2023 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14178/2051 | |
dc.description.abstract | In our study, the effect of the use of autofluorescence (Visually Enhanced Lesion Scope-VELscope) on increasing the success rate of surgical treatment in oral squamous carcinoma (OSCC) was investigated. Our hypothesis was tested on a group of 122 patients suffering from OSCC, randomized into a study and a control group enrolled in our study after meeting the inclusion criteria. The preoperative checkup via VELscope, accompanied by the marking of the range of a loss of fluorescence in the study group, was performed before the surgery. We developed a unique mucosal tattoo marking technique for this purpose. The histopathological results after surgical treatment, i.e., the margin status, were then compared. In the study group, we achieved pathological free margin (pFM) in 55 patients, pathological close margin (pCM) in 6 cases, and we encountered no cases of pathological positive margin (pPM) in the mucosal layer. In comparison, the control group results revealed pPM in 7 cases, pCM in 14 cases, and pFM in 40 of all cases in the mucosal layer. This study demonstrated that preoperative autofluorescence assessment of the mucosal surroundings of OSCC increased the ability to achieve pFM resection 4.8 times in terms of lateral margins. | en |
dc.language.iso | en | |
dc.relation.url | https://www.mdpi.com/2075-4418/13/20/3161 | |
dc.rights | Creative Commons Uveďte původ 4.0 International | cs |
dc.rights | Creative Commons Attribution 4.0 International | en |
dc.title | Clinical Experience with Autofluorescence Guided Oral Squamous Cell Carcinoma Surgery | en |
dcterms.accessRights | openAccess | |
dcterms.license | https://creativecommons.org/licenses/by/4.0/legalcode | |
dc.date.updated | 2023-11-15T20:40:31Z | |
dc.subject.keyword | autofluorescence | en |
dc.subject.keyword | oral squamous cell carcinoma | en |
dc.subject.keyword | surgical treatment | en |
dc.subject.keyword | margin status | en |
dc.relation.fundingReference | info:eu-repo/grantAgreement/UK/I-UK/I-LFP | |
dc.relation.fundingReference | info:eu-repo/grantAgreement/FN/I-FN/I-FNP-08 | |
dc.relation.fundingReference | info:eu-repo/grantAgreement/UK/IRP/aktivita č. 6 | |
dc.date.embargoStartDate | 2023-11-15 | |
dc.type.obd | 73 | |
dc.type.version | info:eu-repo/semantics/publishedVersion | |
dc.identifier.doi | 10.3390/diagnostics13203161 | |
dc.identifier.utWos | 001092360000001 | |
dc.identifier.eidScopus | 2-s2.0-85175551069 | |
dc.identifier.obd | 637144 | |
dc.subject.rivPrimary | 30000::30200::30208 | |
dcterms.isPartOf.name | Diagnostics | |
dcterms.isPartOf.issn | 2075-4418 | |
dcterms.isPartOf.journalYear | 2023 | |
dcterms.isPartOf.journalVolume | 13 | |
dcterms.isPartOf.journalIssue | 20 | |
uk.faculty.primaryId | 111 | |
uk.faculty.primaryName | Lékařská fakulta v Plzni | cs |
uk.faculty.primaryName | Faculty of Medicine in Pilsen | en |
uk.faculty.secondaryId | 54 | |
uk.faculty.secondaryName | Fakultní nemocnice Plzeň | cs |
uk.faculty.secondaryName | University Hospital in Pilsen | en |
uk.department.primaryId | 1435 | |
uk.department.primaryName | Stomatologická klinika | cs |
uk.department.primaryName | Department of Stomatology | en |
uk.department.secondaryId | 5000002730 | |
uk.department.secondaryId | 1361 | |
uk.department.secondaryId | 1344 | |
uk.department.secondaryName | Stomatologická klinika | cs |
uk.department.secondaryName | Department of Stomatology | en |
uk.department.secondaryName | Šiklův ústav patologie | cs |
uk.department.secondaryName | Department of Pathology | en |
uk.department.secondaryName | Ústav anatomie | cs |
uk.department.secondaryName | Department of Anatomy | en |
dc.type.obdHierarchyCs | ČLÁNEK V ČASOPISU::článek v časopisu::původní článek | cs |
dc.type.obdHierarchyEn | JOURNAL ARTICLE::journal article::original article | en |
dc.type.obdHierarchyCode | 73::152::206 | en |
uk.displayTitle | Clinical Experience with Autofluorescence Guided Oral Squamous Cell Carcinoma Surgery | en |