Understanding the interplay between MPyV infection and nuclear lamina
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Autor
Datum vydání
2023Publikováno v
Czech Chemical Society Symposium SeriesRočník / Číslo vydání
21 (5)ISBN / ISSN
ISSN: 2336-7202Metadata
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Abstrakt
The nuclear lamina (NL) is a dense meshwork of intermediate filaments V, type A lamins (lamin A/C), type B lamins and membrane associated proteins. It is located below the inner nuclear membrane. NL maintains the shape and structural integrity of the nucleus and plays an important role in fine-tuning of DNA related processes, e. g. replication or transcription. Also, it has been suggested to play a role in cell defence against pathogens. DNA viruses evolved mechanisms to exploit NL for their own purposes.
Klíčová slova
MPyV infection, lamina, NL, VP1
Trvalý odkaz
https://hdl.handle.net/20.500.14178/2068Licence
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