| dc.contributor.author | Pimková Polidarová, Markéta | |
| dc.contributor.author | Janovec, Václav | |
| dc.contributor.author | Berehovska, Olena | |
| dc.contributor.author | Kůtová, Zuzana | |
| dc.contributor.author | Sedláček, Jindřich | |
| dc.contributor.author | Adámek, Michael | |
| dc.contributor.author | Machara, Aleš | |
| dc.contributor.author | Hirsch, Ivan | |
| dc.contributor.author | Grantz Šašková, Klára | |
| dc.contributor.editor | Černý, Jiří | |
| dc.contributor.editor | Holá, Lucie | |
| dc.contributor.editor | Šímová, Šárka | |
| dc.contributor.editor | Dvořáková, Anna | |
| dc.date.accessioned | 2024-02-21T10:10:52Z | |
| dc.date.available | 2024-02-21T10:10:52Z | |
| dc.date.issued | 2024 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14178/2257 | |
| dc.description.abstract | Chronic hepatitis B (CHB) is a viral liver infection caused by hepatitis B virus (HBV), affecting over 300 million people world-wide. Untreated CHB can lead to liver cirrhosis and hepatocellular carcinoma, causing over 800,000 deaths annually. Current nucleot(s)ide analogue-based therapies effectively slow disease progression and reduce viral load, but require life-long application. Pegylated interferon alpha therapy clears the virus in a small percentage of patients, but has serious side effects. Therefore, a universally effective and definitive cure of CHB is still elusive. | en |
| dc.language.iso | en | |
| dc.publisher | Česká zemědělská univerzita v Praze | |
| dc.relation.url | https://www.virology.cz/ | |
| dc.rights | Creative Commons Uveďte původ 4.0 International | cs |
| dc.rights | Creative Commons Attribution 4.0 International | en |
| dc.title | Inhibition of HBsAg secretion by a novel autophagy inducer | en |
| dcterms.accessRights | openAccess | |
| dcterms.license | https://creativecommons.org/licenses/by/4.0/legalcode | |
| dc.date.updated | 2024-02-21T10:10:52Z | |
| dc.subject.keyword | inhibitor | en |
| dc.subject.keyword | HBsAg | en |
| dc.subject.keyword | HBV | en |
| dc.publisher.publicationPlace | Praha | |
| dc.relation.fundingReference | info:eu-repo/grantAgreement/MSM//LX22NPO5103 | |
| dc.relation.fundingReference | info:eu-repo/grantAgreement/UK/COOP/COOP | |
| dc.date.embargoStartDate | 2024-02-21 | |
| dc.contributor.organizer | Česká zemědělská univerzita Praha, Česká spol. pro biochemii a mol. bilogii, NIVB | |
| dc.type.obd | 110 | |
| dc.type.version | info:eu-repo/semantics/acceptedVersion | |
| dc.identifier.obd | 645023 | |
| dc.subject.rivPrimary | 10000::10600::10607 | |
| dcterms.isPartOf.name | CzechoSlovak Virology Conference 2024 : Book of Abstracts | |
| dcterms.isPartOf.journalYear | 2024 | |
| dcterms.isPartOf.journalVolume | 1 | |
| dcterms.isPartOf.journalIssue | 1 | |
| uk.faculty.primaryId | 115 | |
| uk.faculty.primaryName | Přírodovědecká fakulta | cs |
| uk.faculty.primaryName | Faculty of Science | en |
| uk.department.primaryId | 1034 | |
| uk.department.primaryName | Katedra genetiky a mikrobiologie | cs |
| uk.department.primaryName | Department of Genetics and Microbiology | en |
| uk.event.name | CzechoSlovak Virology Conference 2024 | |
| dc.description.pageRange | 42-42 | |
| dc.type.obdHierarchyCs | ABSTRAKT::abstrakt::abstrakt v elektronické podobě | cs |
| dc.type.obdHierarchyEn | ABSTRACT::abstract::abstract in e-form | en |
| dc.type.obdHierarchyCode | 110::130::136 | en |
| uk.displayTitle | Inhibition of HBsAg secretion by a novel autophagy inducer | en |
