Coade stone has played a significant role in architectural and ornamental design since its inception in the early 18th century. It is well known that earlier, experimental, architectural stoneware products existed, but few ...
We studied the development of soil and soil fauna, as well as selected vegetation parameters important for litter input into soil, in two chronosequences of postmining sites after opencast lignite mining near the town of ...
Background: Russia's military aggression against Ukraine set in motion a large number of refugees. Considerable amount of them came and stayed in Czechia. Refugees represent special vulnerable individuals often affected ...
Background: The sensitivity and specificity of selected antigen detection rapid diagnostic tests (AG-RDTs) for SARS-CoV-2 were determined in the unvaccinated population when the Delta variant was circulating. Viral loads, ...
To date, many viruses have been discovered to infect honey bees. In this study, we used high-throughput sequencing to expand the known virome of the honey bee, Apis mellifera, by identifying several novel DNA viruses. While ...
Background: Cancer development involves alterations in key cellular pathways, with aspartate β-hydroxylase (ASPH) emerging as an important player in tumorigenesis. ASPH is upregulated in various cancer types, where it ...
Identification of a protein minimal fragment amenable to crystallisation can be time- and labour intensive especially if large amounts are required and the protein has a complex fold and functionally important post-translational ...
The acylated pore-forming Repeats in ToXin (RTX) cytolysins alpha-hemolysin (HlyA) and adenylate cyclase toxin (CyaA) preferentially bind to beta 2 integrins of myeloid leukocytes but can also promiscuously bind and ...
Therapeutic options for Alzheimer's disease are limited. Dual compounds targeting two pathways concurrently may enable enhanced effect. The study focuses on tacrine derivatives inhibiting acetylcholinesterase (AChE) and ...
CzechoSlovak Virology Conference 2024 : Book of Abstracts
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The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide.For effective treatment and introduction of appropriate anti-pandemic measures, it is necessary tounderstand the development ...