Zobrazují se záznamy 21-40 z 209

    • Characterization of the input material quality for the production of tisagenlecleucel by multiparameter flow cytometry and its relation to the clinical outcome 

      původní článek

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      Štach, Martin

      ;

      Pytlík, Robert

      ;

      Šmilauerová, Kristýna

      ;

      Rychlá, Jana

      ;

      Mucha, Martin

      ;

      Musil, Jan

      ;

      Koladiya, Abhishek

      ;

      Nemec, Matěj

      ;

      Petráčková, Martina

      ;

      Kaštánková, Iva

      ;

      Pecherková, Pavla

      ;

      Šrámková, Lucie

      ;

      Polgárová, Kamila

      ;

      Trněný, Marek

      ;

      Lesný, Petr

      ;

      Vydra, Jan

      ;

      Otáhal, Pavel

      2023

      ,

      Pathology & Oncology Research

      ,

      29

      (April)

      Tisagenlecleucel (tisa-cel) is a CD19(-)specific CAR-T cell product approved for the treatment of relapsed/refractory (r/r) DLBCL or B-ALL. We have followed a group of patients diagnosed with childhood B-ALL (n = 5), adult ...

    • Flood Simulations Using a Sensor Network and Support Vector Machine Model 

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      Langhammer, Jakub

      2023

      ,

      Water

      ,

      15

      (11)

      This study aims to couple the support vector machine (SVM) model with a hydrometeorological wireless sensor network to simulate different types of flood events in a montane basin. The model was tested in the mid-latitude ...

    • Automatic forest cover classification using Sentinel-2 multispectral satellite data and machine learning algorithms in Google Earth Engine 

      Automatická klasifikácia lesnej pokrývky pomocou multispektrálnych satelitných dát Sentinel-2 a algoritmov strojového učenia v Google Earth Engine

      původní článek

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      vydavatelská verze

      Ikona Jiná licence

      Onačillová, Katarína

      ;

      Krištofová, Veronika

      ;

      Paluba, Daniel

      2023

      ,

      Acta Geographica Universitatis Comenianae

      ,

      67

      (2)

      Forest cover plays an essential role in maintaining ecological equilibrium, mitigating climate change, and securing a sustainable future for both humanity and the planet. Most countries conduct forest inventory or remote ...

    • Dendrometers challenge the 'moon wood concept' by elucidating the absence of lunar cycles in tree stem radius oscillation 

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      Tumajer, Jan

      ;

      Braun, Sabine

      ;

      Burger, Andreas

      ;

      Scharnweber, Tobias

      ;

      Smiljanic, Marko

      ;

      Walthert, Lorenz

      ;

      Zweifel, Roman

      ;

      Wilmking, Martin

      2023

      ,

      Scientific Reports

      ,

      13

      (1)

      Wood is a sustainable natural resource and an important global commodity. According to the 'moon wood theory', the properties of wood, including its growth and water content, are believed to oscillate with the lunar cycle. ...

    • Reprogramming of the developing heart by Hif1a-deficient sympathetic system and maternal diabetes exposure 

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      Kolesová, Hana

      ;

      Hrabalová, Petra

      ;

      Bohuslavova, Romana

      ;

      Abaffy, Pavel

      ;

      Fabriciova, Valeria

      ;

      Sedmera, David

      ;

      Pavlinkova, Gabriela

      2024

      ,

      Frontiers in Endocrinology

      ,

      15

      (March)

      Introduction: Maternal diabetes is a recognized risk factor for both short-term and long-term complications in offspring. Beyond the direct teratogenicity of maternal diabetes, the intrauterine environment can influence ...

    • Metodika tvorby textů v otevřeném internetovém prostoru pro vysokoškolské vzdělávání formou e-learningu 

      Methodology of text creation in open an internet space for higher education through e-learning

      certifikovaná metodika

      open access

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      Dlouhá, Jana

      ;

      Braniš, Martin

      ;

      Dlouhý, Jiří

      ;

      Jančaříková, Kateřina

      ;

      Jančařík, Antonín

      ;

      Šauer, Petr

      2012

      Metodika tvorby textů v otevřeném internetovém prostoru poskytuje základní teoretický i praktický rámec pro využití otevřeného internetového prostoru jako nástroje pro výuku studentů na vysokých školách, která je vedena ...

    • Interleaflet organization of membrane nanodomains: What can(not) be resolved by FRET? 

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      Chmelová, Barbora

      ;

      Davidović, David

      ;

      Šachl, Radek

      2023

      ,

      Biophysical Journal

      ,

      122

      (11)

      Plasma membranes as well as their simplified model systems show an inherent nanoscale heterogeneity. As a result of strong interleaflet interactions, these nanoheterogeneities (called here lipid nanodomains) can be found ...

    • Specific Immunity to SARS-CoV-2 Infection 

      abstrakt v elektronické podobě

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      postprint

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      Vránová, Lucie

      ;

      Poláková, Ingrid

      ;

      Tachezy, Ruth

      ;

      Vaníková, Šárka

      ;

      Musil, Jan

      ;

      Saláková, Martina

      ;

      Vaníčková, Marie

      ;

      Vencálek, Ondřej

      ;

      Holub, Martin

      ;

      Bohoněk, Miloš

      ;

      Beran, Ondřej

      ;

      Řezáč, David

      ;

      Dresler, Jiří

      ;

      Kabíčková, Hana

      ;

      Šmahel, Michal

      2024

      ,

      Praha

      ,

      Česká zemědělská univerzita

      ,

      CzechoSlovak Virology Conference 2024 : Book of Abstracts

      ,

      1

      (1)

      The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide.For effective treatment and introduction of appropriate anti-pandemic measures, it is necessary tounderstand the development ...

    • The differences in virome from distinct anatomical locations in psoriasis patients 

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      Kadlečková, Dominika

      ;

      Saláková, Martina

      ;

      Šmahelová, Jana

      ;

      Rob, Filip

      ;

      Nováková, Michaela

      ;

      Tachezy, Ruth

      2024

      ,

      Praha

      ,

      Česká zemědělská univerzita

      ,

      CzechoSlovak Virology Conference 2024 : Book of Abstracts

      ,

      1

      (1)

      Psoriasis, a chronic autoimmune inflammatory disorder affecting 2-3% of the global population,exhibits a multifactorial aetiology with a significant genetic component and triggers such as trauma orinfection.

    • UV-C irradiation as an effective tool for sterilization of porcine chimeric VP1-PCV2bCap recombinant vaccine 

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      Vrablikova, Alena

      ;

      Fojtikova, Martina

      ;

      Hezova, Renata

      ;

      Simeckova, Pavlina

      ;

      Brezani, Veronika

      ;

      Strakova, Nicol

      ;

      Fraiberk, Martin

      ;

      Kotoucek, Jan

      ;

      Masek, Josef

      ;

      Psikal, Ivan

      2023

      ,

      Scientific Reports

      ,

      13

      (1)

      Ultraviolet irradiation is an effective method of virus and bacteria inactivation. The dose of UV-C light necessary for baculovirus inactivation by measurement of fluorescent GFP protein produced by baculovirus expression ...

    • Hepatitis B virus hijacks host E2/E3 ubiquitin ligase, UBE2O, for viral nucleocapsid assembly and virion egress 

      abstrakt v elektronické podobě

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      Lubyová, Barbora

      ;

      Tikalová, Eva

      ;

      Janovec, Václav

      ;

      Rjabčenko, Boris

      ;

      Krulová, Kristýna

      ;

      Huerfano Meneses, Sandra

      ;

      Hirsch, Ivan

      ;

      Weber, Jan

      2024

      ,

      Praha

      ,

      CzechoSlovak Virology Conference 2024 : Book of abstracts

      ,

      1

      (1)

      Chronic hepatitis B (CHB) represents a serious liver disease that is caused by infection of Hepatitis Bvirus (HBV). CHB is associated with severe liver conditions ranging from fibrosis and cirrhosis tohepatocellular carcinoma ...

    • Effect of ADAR1 enzyme knockout on HCV replication 

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      Kubů, Martin

      ;

      Pospíšek, Martin

      ;

      Vopálenský, Václav

      ;

      Roučová, Kristina

      2024

      ,

      Praha

      ,

      Česká zemědělská univerzita

      ,

      CzechoSlovak Virology Conference 2024 : Book of abstracts

      ,

      1

      (1)

      The hepatitis C virus (HCV) is a member of the Flaviviridae family whose genome consists of a +RNAmolecule. It causes hepatitis C, a disease that affects tens of millions of people worldwide. Althoughthere is an effective ...

    • Inhibition of HBsAg secretion by a novel autophagy inducer 

      abstrakt v elektronické podobě

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      Pimková Polidarová, Markéta

      ;

      Janovec, Václav

      ;

      Berehovska, Olena

      ;

      Kůtová, Zuzana

      ;

      Sedláček, Jindřich

      ;

      Adámek, Michael

      ;

      Machara, Aleš

      ;

      Hirsch, Ivan

      ;

      Grantz Šašková, Klára

      2024

      ,

      Praha

      ,

      Česká zemědělská univerzita v Praze

      ,

      CzechoSlovak Virology Conference 2024 : Book of Abstracts

      ,

      1

      (1)

      Chronic hepatitis B (CHB) is a viral liver infection caused by hepatitis B virus (HBV), affecting over 300 million people world-wide. Untreated CHB can lead to liver cirrhosis and hepatocellular carcinoma, causing over ...

    • Development of modern immunization agent against bovine papillomavirus type 1 infection based on BPV1 L1 recombinant protein 

      původní článek

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      Vráblíková, Alena

      ;

      Brezáni, Veronika

      ;

      Pšikal, Ivan

      ;

      Fraiberk, Martin

      ;

      Šebela, Marek

      ;

      Fojtíková, Martina

      ;

      Kulich, Pavel

      ;

      Héžová, Renata

      ;

      Mašek, Josef

      2023

      ,

      Frontiers in Veterinary Science

      ,

      10

      (March)

      Bovine papillomavirus type 1 L1 protein was produced in a baculovirus expression system and purified as virus-like particles (VLPs) by affinity chromatography using lectins. The morphological integrity of VLPs was confirmed ...

    • Antifungal triazoles affect key non-target metabolic pathways in Solanum lycopersicum L. plants 

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      Hýsková, Veronika

      ;

      Jakl, Michal

      ;

      Jaklová Dytrtová, Jana

      ;

      Zeljković, Sanja Ćavar

      ;

      Vrobel, Ondřej

      ;

      Bělonožníková, Kateřina

      ;

      Kavan, Daniel

      ;

      Křížek, Tomáš

      ;

      Šimonová, Alice

      ;

      Vašková, Marie

      ;

      Kovač, Ishak

      ;

      Račko Žufić, Antoniana

      ;

      Ryšlavá, Helena

      2023

      ,

      Ecotoxicology and Environmental Safety

      ,

      268

      (December)

      Several 1,2,4-triazoles are widely used as systemic fungicides in agriculture because they inhibit fungal 14ɑ-demethylase. However, they can also act on many non-target plant enzymes, thereby affecting phytohormonal balance, ...

    • Triazoles as a Potential Threat to the Nutritional Quality of Tomato Fruits 

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      Hýsková, Veronika

      ;

      Jakl, Michal

      ;

      Jaklová Dytrtová, Jana

      ;

      Cavar Zeljkovic, Sanja

      ;

      Vrobel, Ondrej

      ;

      Bělonožníková, Kateřina

      ;

      Kavan, Daniel

      ;

      Křížek, Tomáš

      ;

      Šimonová, Alice

      ;

      Vašková, Marie

      ;

      Kovač, Ishak

      ;

      Račko Žufić, Antoniana

      ;

      Ryšlavá, Helena

      2023

      ,

      Metabolites

      ,

      13

      (9)

      Triazole fungicides can threaten plants as abiotic stressors but can also positively affect plant defense by inducing priming. Thus, plant yield is also both protected and endangered by triazoles that may influence several ...

    • Synthesis and migrastatic activity of cytochalasin analogues lacking a macrocyclic moiety 

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      Formánek, Bedřich

      ;

      Dupommier, Dorian

      ;

      Volfová, Tereza

      ;

      Rimpelová, Silvie

      ;

      Škarková, Aneta

      ;

      Herciková, Jana

      ;

      Rösel, Daniel

      ;

      Brábek, Jan

      ;

      Perlíková, Pavla

      2024

      ,

      RSC Medicinal Chemistry

      ,

      15

      (1)

      Cytochalasans are known as inhibitors of actin polymerization and for their cytotoxic and migrastatic activity. In this study, we synthesized a series of cytochalasin derivatives that lack a macrocyclic moiety, a structural ...

    • The translational oscillation in oocyte and early embryo development 

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      Iyyapan, Rajan

      ;

      Aleshkina, Daria

      ;

      Ming, Hao

      ;

      Dvořan, Michal

      ;

      Kakavand, Kianoush

      ;

      Jansová, Denisa

      ;

      del Llano Solanas, Edgar

      ;

      Gahurová, Lenka

      ;

      Bruce, Alexander William

      ;

      Mašek, Tomáš

      ;

      Pospíšek, Martin

      ;

      Horvat, Filip

      ;

      Kubelka, Michal

      ;

      Jiang, Zongliang

      ;

      Šušor, Andrej

      2023

      ,

      Nucleic Acids Research

      ,

      51

      (22)

      Translation is critical for development as transcription in the oocyte and early embryo is silenced. To illustrate the translational changes during meiosis and consecutive two mitoses of the oocyte and early embryo, we ...

    • Detection of viable SARS-CoV-2 on the hands of hospitalized children with COVID-19 

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      Haas, Meryl

      ;

      Fürhacker, Paola

      ;

      Hodek, Jan

      ;

      Stangl, Petra

      ;

      Alon, Isabelle

      ;

      Kainz, Katharina

      ;

      Fajgelj, Veronika

      ;

      Mädel, Clemens

      ;

      Dotzler, Sophia

      ;

      Götzinger, Florian

      ;

      Ulrychová, Lucie

      ;

      Preuner, Sandra

      ;

      Fortschegger, Michaela

      ;

      Schinnerl, Dagmar

      ;

      Walter, Christina

      ;

      Obrová, Klára

      ;

      Weber, Jan

      ;

      Zacharasiewicz, Angela

      ;

      Lion, Thomas

      2023

      ,

      Clinical Microbiology and Infection

      ,

      29

      (9)

      Potential routes of SARS-CoV-2 transmission have been a matter of debate since the early phase of the current COVID-19 pandemic. Similar to other respiratory viruses, airborne droplets exhaled by an infected individual and ...

    • Measuring and mapping the existence of phantom borders at a local scale: example of Sudetenland in Czechia 

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      Netrdová, Pavlína

      ;

      Korčák, Matěj

      ;

      Nosek, Vojtěch

      2024

      ,

      Journal of Maps

      ,

      20

      (1)

      This study presents an innovative methodological approach for quantitatively measuring and mapping the existence of phantom borders. Phantom borders are former political borders that have not existed for decades, but their ...