Zobrazují se záznamy 1361-1380 z 1843

    • Effects of Complex Training on Jumping and Change of Direction Performance, and Post-Activation Performance Enhancement Response in Basketball Players 

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      Biel, Piotr

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      Ewertowska, Paulina

      ;

      Šťastný, Petr

      ;

      Krzysztofik, Michal

      2023

      ,

      Sports

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      11

      (9)

      Exercise order is one of the significant factors modulating training effects. Therefore, the aim of this study was to compare the effectiveness of an 8-week complex (CPX) training program utilizing intra-CPX active recovery ...

    • Catching a New Zeolite as a Transition Material during Deconstruction 

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      Yue, Qiudi

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      Steciuk, Gwladys

      ;

      Mazur, Michal

      ;

      Zhang, Jin

      ;

      Petrov, Oleg

      ;

      Shamzhy, Mariya

      ;

      Liu, Mingxiu

      ;

      Palatinus, Lukáš

      ;

      Čejka, Jiří

      ;

      Opanasenko, Maksym

      2023

      ,

      Journal of the American Chemical Society

      ,

      145

      (16)

      Zeolites are key materials in both basic research and industrial applications. However, their synthesis is neither diverse nor applicable to labile frameworks because classical procedures require harsh hydrothermal conditions, ...

    • The detection of hypoxia markers in non-HPV and HPV-associated head and neck cancers: implications to patient survival 

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      Šmahelová, Jana

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      Pokrývková, Barbora

      ;

      Šťovíčková, Eliška

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      Vencálek, Ondřej

      ;

      Šmahel, Michal

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      Grega, Marek

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      Klozar, Jan

      ;

      Tachezy, Ruth

      2023

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      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      In the microenvironment of growing solid tumors, oxygen level often decreases and a hypoxic state is induced. This can lead to a worse treatment response and poor patient prognosis. One of the hypoxia-responsive genes ...

    • Can the type of oncogenic transformation by human papillomaviruses influence the choice of cancer immunotherapy? 

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      Šmahel, Michal

      ;

      Nunvář, Jaroslav

      2023

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      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      High-risk human papillomaviruses can induce malignant transformation of cells resulting in anogenital cancers, particularly cervical cancer (CC), and a proportion of head and neck squamous cell carcinomas ...

    • Mouse PML protein isoforms and their role in Mouse Polyomavirus infection 

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      Anderová, Karolína

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      Rjabčenko, Boris

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      Šroller, Vojtěch

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      Horníková, Lenka

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      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2023

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      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      Promyelocytic leukaemia nuclear bodies (PML NBs) are dynamic, spherical, membrane-lessstructures composed of the main scaffold PML protein and a variety of stable or transient partner proteins. Apart from ...

    • Sand Flies and Toscana Virus 

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      Jančářová, Magdaléna

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      Polanská, Nikola

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      Ratinier, Maxime

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      Arnaud, Frederick

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      Stejskalová, Markéta

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      Thiesson, Adrien

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      Rehbergerová, Markéta

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      Kohl, Alain

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      Volf, Petr

      2023

      ,

      Česká společnost chemická

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      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      Phlebovirus toscanaense (Toscana virus, TOSV) from the Phenuiviridae family is an emerging but still neglected human pathogen. Infections vary from non-symptomatic forms through febrile illness to CNS disease, rarely death. ...

    • Understanding the interplay between MPyV infection and nuclear lamina 

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      Bruštíková, Kateřina

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      Rjabčenko, Boris

      ;

      Forstová, Jitka

      ;

      Horníková, Lenka

      2023

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      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      The nuclear lamina (NL) is a dense meshwork of intermediate filaments V, type A lamins (lamin A/C), type B lamins and membrane associated proteins. It is located below the inner nuclear membrane. NL maintains the shape and ...

    • PML nuclear bodies orchestrate antiviral response in HBV-infected hepatocytes 

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      Janovec, Václav

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      Rjabčenko, Boris

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      Lubyová, Barbora

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      Huerfano Meneses, Sandra

      ;

      Weber, Jan

      ;

      Hirsch, Ivan

      ;

      Grantz Šašková, Klára

      2023

      ,

      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      Promyelocytic leukaemia nuclear bodies (PML-NBs) play roles in various cellular functions and represent a key component of antiviral defense. In the case of hepatitis B virus (HBV), the antiviral ...

    • MiRNA146a is a key component of immunnosupressive environment of hepatocytes chronically infected with HBV and melanoma cells 

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      Berehovska, Olena

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      Pimková Polidarová, Markéta

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      Janovec, Václav

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      Hirsch, Ivan

      ;

      Grantz Šašková, Klára

      2023

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      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      Interferon alfa (IFNα) is a pro-inflammatory cytokine with antiviral properties. Our project focuses on Toll-like receptors (TLR)7/9, which upon activation lead to a massive production of INFα.1Therefore, the process needs ...

    • Role of the PML nuclear bodies and its associated histones chaperones in the remodeling of mouse polyomavirus minichromosomes 

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      Rjabčenko, Boris

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      Satratzemis, Christos

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2023

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      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      Polyomaviruses (PyVs) are small non-enveloped viruses replicating in the host cell nucleus. Viral replication centers (VRCs) share features with cellular euchromatic or heterochromatic regions, depending on the stage of ...

    • STING agonists activate multiple regulated cell death mechanisms in monocytes 

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      Pimková Polidarová, Markéta

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      Hirsch, Ivan

      ;

      Brázdová, Andrea

      ;

      Grantz Šašková, Klára

      2023

      ,

      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      Stimulation of the innate immune responses using agonist of pattern recognition receptors is one of the investigated therapeutic approaches for treatment of chronic diseases, such as cancer or chronic ...

    • Torque teno virus infection among psoriasis patients on biologic therapy 

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      Saláková, Martina

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      Šmahelová, Jana

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      Kadlečková, Dominika

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      Tachezy, Ruth

      2023

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      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      Torque teno virus (TTV) is a ubiquitous member of the healthy human virome with broad tissue tropism. TTV can induce chronic active infection without clinical manifestations. Although little is known about ...

    • Creating a cell line suitable for investigation into the ADAR1 role in hepatitis C virus replication 

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      Roučová, Kristina

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      Vopálenský, Václav

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      Mašek, Tomáš

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      Del Llano, Edgar

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      Provazník, Jan

      ;

      Landry, Jonathan J.M.

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      Azeveda, Nayara

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      Ehler, Edvard

      ;

      Kubů, Martin

      ;

      Beneš, Vladimír

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      Pospíšek, Martin

      2023

      ,

      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      Adenosine deaminases acting on RNA (ADAR) perform the adenosine to inosine (A-to-I) type of editing. Out of the three human ADAR proteins, ADAR1 is responsible for the majority of A-to-I editing of dsRNA outside the ...

    • Absence of 5' methylguanosine cap in postreplicative genes' transcripts of Vaccinia virus 

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      Vopálenský, Václav

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      Sýkora, Michal

      ;

      Mělková, Zora

      ;

      Barvík, Ivan

      ;

      Mašek, Tomáš

      ;

      Horáčková, Kamila

      ;

      Pospíšek, Martin

      2023

      ,

      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      The Vaccinia virus (VACV) played a pivotal role in the discovery of the 5' mRNA. Over the past decades, VACV investigation has contributed extensively to understanding the mechanism behind 5' mRNA cap synthesis. ...

    • Blood parasites (Trypanosoma, Leucocytozoon, Haemoproteus) in the Eurasian sparrowhawk (Accipiter nisus): diversity, incidence and persistence of infection at the individual level 

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      Svobodová, Milena

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      Čepička, Ivan

      ;

      Zídková, Lenka

      ;

      Kassahun, Aysheshm

      ;

      Votýpka, Jan

      ;

      Peške, Lubomír

      ;

      Hrazdilová, Kristýna

      ;

      Brzoňová, Jana

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      Voříšek, Petr

      ;

      Weidinger, Karel

      2023

      ,

      BioMed Central

      ,

      Parasites & Vectors

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      16

      (1)

      Background :A high prevalence of parasites may result from life-long persistence of infection or from high reinfection rates. We have studied blood parasites in a breeding population of the accipitrid raptor, Eurasian ...

    • Same data, different conclusions: Radical dispersion in empirical results when independent analysts operationalize and test the same hypothesis 

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      Schweinsberg, Martin

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      Feldman, Michael

      ;

      Staub, Nicola

      ;

      van den Akker, Olmo R

      ;

      van Aert, Robbie C. M

      ;

      van Assen, Marcel A. L. M

      ;

      Liu, Yang

      ;

      Althoff, Tim

      ;

      Heer, Jeffrey

      ;

      Kale, Alex

      ;

      Mohamed, Zainab

      ;

      Amireh, Hashem

      ;

      Prasad, Vaishali Venkatesh

      ;

      Bernstein, Abraham

      ;

      Robinson, Emily

      ;

      Snellman, Kaisa

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      Sommer, S. Amy

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      Otner, Sarah M. G

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      Robinson, David

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      Madan, Nikhil

      ;

      Silberzahn, Raphael

      ;

      Goldstein, Pavel

      ;

      Tierney, Warren

      ;

      Murase, Toshio

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      Mandl, Benjamin

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      Viganola, Domenico

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      Strobl, Carolin

      ;

      Schaumans, Catherine B. C

      ;

      Kelchtermans, Stijn

      ;

      Naseeb, Chan

      ;

      Garrison, S. Mason

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      Yarkoni, Tal

      ;

      Chan, C. S. Richard

      ;

      Adie, Prestone

      ;

      Alaburda, Paulius

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      Albers, Casper

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      Alspaugh, Sara

      ;

      Alstott, Jeff

      ;

      Nelson, Andrew A

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      de la Rubia, Eduardo Arinno

      ;

      Arzi, Adbi

      ;

      Bahnik, Stepan

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      Baik, Jason

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      Balling, Laura Winther

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      Banker, Sachin

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      Baranger, David A. A

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      Barr, Dale J

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      Barros-Rivera, Brenda

      ;

      Bauer, Matt

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      Blaise, Enuh

      ;

      Boelen, Lisa

      ;

      Carbonell, Katerina Bohle

      ;

      Briers, Robert A

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      Burkhard, Oliver

      ;

      Canela, Miguel-Angel

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      Castrillo, Laura

      ;

      Catlett, Timothy

      ;

      Chen, Olivia

      ;

      Clark, Michael

      ;

      Cohn, Brent

      ;

      Coppock, Alex

      ;

      Cuguero-Escofet, Natalia

      ;

      Curran, Paul G

      ;

      Cyrus-Lai, Wilson

      ;

      Dai, David

      ;

      Dalla Riva, Giulio Valentino

      ;

      Danielsson, Henrik

      ;

      Russo, Rosaria de F. S. M

      ;

      de Silva, Niko

      ;

      Derungs, Curdin

      ;

      Dondelinger, Frank

      ;

      de Souza, Carolina Duarte

      ;

      Dube, B. Tyson

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      Dubova, Marina

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      Dunn, Ben Mark

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      Edelsbrunner, Peter Adriaan

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      Finley, Sara

      ;

      Fox, Nick

      ;

      Gnambs, Timo

      ;

      Gong, Yuanyuan

      ;

      Grand, Erin

      ;

      Greenawalt, Brandon

      ;

      Han, Dan

      ;

      Hanel, Paul H. P

      ;

      Hong, Antony B

      ;

      Hood, David

      ;

      Hsueh, Justin

      ;

      Huang, Lilian

      ;

      Hui, Kent N

      ;

      Hultman, Keith A

      ;

      Javaid, Azka

      ;

      Jiang, Lily Ji

      ;

      Jong, Jonathan

      ;

      Kamdar, Jash

      ;

      Kane, David

      ;

      Kappler, Gregor

      ;

      Kaszubowski, Erikson

      ;

      Kavanagh, Christopher M

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      Khabsa, Madian

      ;

      Ropovik, Ivan

      2021

      ,

      Organizational Behavior and Human Decision Processes

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      165

      (1)

      In this crowdsourced initiative, independent analysts used the same dataset to test two hypotheses regarding the effects of scientists' gender and professional status on verbosity during group meetings. Not only the analytic ...

    • Genetic analysis challenges the presence of Ixodes inopinatus in Central Europe: Development of a multiplex PCR to distinguish I. inopinatus from I. ricinus 

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      Hrazdilová, Kristýna

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      Daněk, Ondřej

      ;

      Hrbatová, Alena

      ;

      Červená, Barbora

      ;

      Nosková, Eva

      ;

      Adamík, Peter

      ;

      Votýpka, Jan

      ;

      Mihalca, Andrei Daniel

      ;

      Noureddine, Mechouk

      ;

      Modrý, David

      ;

      Žůrek, Luděk

      2023

      ,

      Parasites & Vectors

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      16

      (1)

      Background Ixodes ricinus is an important vector of several pathogens, primarily in Europe. Recently, Ixodes inopinatus was described from Spain, Portugal, and North Africa and then reported from several European countries. ...

    • Exploring the molecular mechanisms used by human BK polyomavirus to activate immune responses in "reservoir cells" 

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      Bruštíková, Kateřina

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      Rjabčenko, Boris

      ;

      Forstová, Jitka

      ;

      Huerfano Meneses, Sandra

      2023

      ,

      Czech Chemical Society Symposium Series

      ,

      21

      (5)

      At present, the Polyomaviridae family contains 14 human polyomaviruses (PyVs), among the most important are Merkel cell polyomavirus (MCPyV), the etiological agent of 80% of Merkel cell carcinomas, JCPyV and BKPyV causing ...

    • Characterization of a human placental clearance system to regulate serotonin levels in the fetoplacental unit 

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      Štaud, František

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      Pan, Xin

      ;

      Karahoda, Rona

      ;

      Dong, Xiaojing

      ;

      Kastner, Petr

      ;

      Horáčková, Hana

      ;

      Váchalová, Veronika

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      Markert, Udo R.

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      Abad, Cilia

      2023

      ,

      Reproductive Biology and Endocrinology

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      21

      (1)

      Background Serotonin (5-HT) is a biogenic monoamine with diverse functions in multiple human organs and tissues. During pregnancy, tightly regulated levels of 5-HT in the fetoplacental unit are critical for proper placental ...

    • TET protein inhibitors: Potential and limitations 

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      Kaplánek, Robert

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      Kejík, Zdeněk

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      Hajduch, Jan

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      Veselá, Kateřina

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      Kučnirová, Kateřina

      ;

      Skaličková, Markéta

      ;

      Venhauerová, Anna

      ;

      Hosnedlová, Božena

      ;

      Hromádka, Róbert

      ;

      Dytrych, Petr

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      Novotný, Petr

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      Abramenko, Nikita

      ;

      Antonyová, Veronika

      ;

      Hoskovec, David

      ;

      Babula, Petr

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      Masařík, Michal

      ;

      Martásek, Pavel

      ;

      Jakubek, Milan

      2023

      ,

      Biomedicine & Pharmacotherapy

      ,

      166

      (October)

      TET proteins (methylcytosine dioxygenases) play an important role in the regulation of gene expression. Dysregulation of their activity is associated with many serious pathogenic states such as oncological diseases. ...