Zobrazují se záznamy 801-820 z 1818

    • Why do teachers leave schools? Evidence from lower secondary schools in the Czech Republic 

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      open access

      vydavatelská verze

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      Straková, Jana

      ;

      Simonová, Jaroslava

      2024

      ,

      International Journal of Educational Management

      ,

      neuveden

      (18.2.2024)

      Purpose - This study aims to supplement the international knowledge on factors determining retention in theteaching profession with findings from the Czech Republic. The study aims to answer the question of whatfactors on ...

    • Proteogenomic Characterization of Pseudomonas veronii SM-20 Growing on Phenanthrene as Only Carbon and Energy Source 

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      open access

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      Zavala Meneses, Sofia Guadalupe

      ;

      Firrincieli, Andrea

      ;

      Chalova, Petra

      ;

      Pajer, Petr

      ;

      Checcucci, Alice

      ;

      Škultéty, Ľudovít

      ;

      Cappelletti, Martina

      2024

      ,

      Microorganisms

      ,

      12

      (4)

      In this study, we conducted an extensive investigation of the biodegradation capabilities and stress response of the newly isolated strain Pseudomonas veronii SM-20 in order, to assess its potential for bioremediation of ...

    • More Than Meets the Reply: Examining Emotional Belonging in Far-Right Social Media Space 

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      omezený přístup

      vydavatelská verze

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      Collins, Jonathan

      2024

      ,

      Social media + Society

      ,

      10

      (3)

      This article challenges prevailing assumptions that fringe social media platforms predominantly serve as unmoderated hate-filled spaces for far-right communication by examining the userbase's emotional connection to these ...

    • The effect of aspartate β-hydroxylase inhibition on cancer immunotherapy 

      abstrakt v elektronické podobě

      open access

      postprint

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      Johari, Shweta Dilip

      ;

      Krausová, Kateřina

      ;

      Žucha, Barbora

      ;

      Madureira Trufen, Carlos Eduardo

      ;

      Poláková, Ingrid

      ;

      Olsen, Mark

      ;

      Šmahel, Michal

      2024

      ,

      Neuveden

      Aspartate β-hydroxylase (ASPH) is overexpressed in 70-90% of various solid tumors, contributing to tumor cell proliferation, migration, and invasion. In addition, recombinant ASPH inhibits natural killer (NK) cells, but ...

    • Self-administered mindfulness interventions reduce stress in a large, randomized controlled multi-site study 

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      Sparacio, Alessandro

      ;

      IJzerman, Hans

      ;

      Ropovik, Ivan

      ;

      Giorgini, Filippo

      ;

      Spiessens, Christoph

      ;

      Uchino, Bert N.

      ;

      Landvatter, Joshua

      ;

      Tacana, Tracey

      ;

      Diller, Sandra J.

      ;

      Derrick, Jaye L.

      ;

      Segundo, Joahana

      ;

      Pierce, Jace D.

      ;

      Ross, Robert M.

      ;

      Francis, Zoë

      ;

      LaBoucane, Amanda

      ;

      Ma-Kellams, Christine

      ;

      Ford, Maire B.

      ;

      Schmidt, Kathleen

      ;

      Wong, Celia C.

      ;

      Higgins, Wendy C.

      ;

      Stone, Bryant M.

      ;

      Stanley, Samantha K.

      ;

      Ribeiro, Gianni

      ;

      Fuglestad, Paul T.

      ;

      Jaklin, Valerie

      ;

      Kübler, Andrea

      ;

      Ziebell, Philipp

      ;

      Jewell, Crystal L.

      ;

      Kovas, Yulia

      ;

      Allahghadri, Mahnoosh

      ;

      Fransham, Charlotte

      ;

      Baranski, Michael F.

      ;

      Burgess, Hannah

      ;

      Benz, Annika B.E.

      ;

      DeSousa, Maysa

      ;

      Nylin, Catherine E.

      ;

      Brooks, Janae C.

      ;

      Goldsmith, Caitlyn M.

      ;

      Benson, Jessica M.

      ;

      Griffin, Siobhán M.

      ;

      Dunne, Stephen

      ;

      Davis, William E.

      ;

      Watermeyer, Tam J.

      ;

      Meese, William B.

      ;

      Howell, Jennifer L.

      ;

      Standiford Reyes, Laurel

      ;

      Strickland, Megan G.

      ;

      Dickerson, Sally S.

      ;

      Pescatore, Samantha

      ;

      Skakoon-Sparling, Shayna

      ;

      Wunder, Zachary I.

      ;

      Day, Martin V.

      ;

      Brenton, Shawna

      ;

      Linden, Audrey H.

      ;

      Hawk, Christopher E.

      ;

      O’Brien, Léan V.

      ;

      Urgyen, Tenzin

      ;

      McDonald, Jennifer S.

      ;

      van der Schans, Kim Lien

      ;

      Blocker, Heidi

      ;

      Ng Tseung-Wong, Caroline

      ;

      Jiga-Boy, Gabriela M.

      2024

      ,

      Nature Human Behaviour

      ,

      8

      (11.6.2024)

      Mindfulness witnessed a substantial popularity surge in the past decade, especially as digitally self-administered interventions became available at relatively low costs. Yet, it is uncertain whether they effectively help ...

    • Defects in B-lymphopoiesis and B-cell maturation underlie prolonged B-cell depletion in ANCA-associated vasculitis 

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      Thiel, Jens

      ;

      Schmidt, Franziska M

      ;

      Lorenzetti, Raquel

      ;

      Troilo, Arianna

      ;

      Janowska, Iga

      ;

      Nießen, Lena

      ;

      Pfeiffer, Sophie

      ;

      Staniek, Julian

      ;

      Benassini, Bruno

      ;

      Bott, Marei-Theresa

      ;

      Korzhenevich, Jakov

      ;

      Konstantinidis, Lukas

      ;

      Burgbacher, Frank

      ;

      Dufner, Ann-Katrin

      ;

      Frede, Natalie

      ;

      Voll, Reinhard E

      ;

      Stuchlý, Jan

      ;

      Bakardjieva, Marina

      ;

      Kalina, Tomáš

      ;

      Smulski, Cristian Roberto

      ;

      Venhoff, Nils

      ;

      Rizzi, Marta

      2024

      ,

      Annals of the Rheumatic Diseases

      ,

      83

      (11)

      OBJECTIVES: B-cell depletion time after rituximab (RTX) treatment is prolonged in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) compared with other autoimmune diseases. We investigated central and ...

    • Tviblindi algorithm identifies branching developmental trajectories of human B-cell development and describes abnormalities in RAG-1 and WAS patients 

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      Bakardjieva, Marina

      ;

      Pelák, Ondřej

      ;

      Wentink, Marjolein

      ;

      Glier, Hana

      ;

      Novák, David

      ;

      Stančíková, Jitka

      ;

      Kužílková, Daniela

      ;

      Mejstříková, Ester

      ;

      Janowska, Iga

      ;

      Rizzi, Marta

      ;

      van der Burg, Mirjam

      ;

      Stuchlý, Jan

      ;

      Kalina, Tomáš

      2024

      ,

      European Journal of Immunology

      ,

      54

      (12)

      Detailed knowledge of human B-cell development is crucial for the proper interpretation of inborn errors of immunity and malignant diseases. It is of interest to understand the kinetics of protein expression changes during ...

    • Giant Cell Temporal Arteritis Followed by Severe Encephalopathy Induced by Immunotherapy in a Patient with Metastatic Renal Cell Carcinoma Achieving Durable Partial Response: A Case Report 

      kazuistika

      open access

      vydavatelská verze

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      Fiala, Ondřej

      ;

      Tkadlecová, Michaela

      ;

      Pivovarčíková, Kristýna

      ;

      Baxa, Jan

      ;

      Stránský, Petr

      ;

      Šiková, Dominika

      ;

      Hora, Milan

      ;

      Fínek, Jindřich

      2024

      ,

      Case Reports in Oncology

      ,

      17

      (1)

      Introduction: Combined immuno-oncology (IO) regimens are the cornerstone of the current front-line systemic therapy for metastatic renal cell carcinoma (mRCC). Despite the fact that combined IO regimens show high efficacy, ...

    • Steady survival improvements in soft tissue and bone sarcoma in the Nordic countries through 50 years 

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      vydavatelská verze

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      Tichánek, Filip

      ;

      Försti, Asta

      ;

      Hemminki, Otto

      ;

      Hemminki, Akseli

      ;

      Hemminki, Kari Jussi

      2024

      ,

      Cancer Epidemiology

      ,

      29

      (October)

      Purpose: Sarcomas are rare cancers with many subtypes in soft tissues, bone and cartilage. International survival trends in these cancers are not well known. We present 50-year survival trends for soft tissue sarcoma (STS) ...

    • Adenotonsillar pathology in mucopolysaccharidoses - lysosomal storage predominates in paracortical CD63+ cells 

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      open access

      vydavatelská verze

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      Murgašová, Lenka

      ;

      Hůlková, Helena

      ;

      Barešová, Veronika

      ;

      Jurovčík, Michal

      ;

      Stříteský, Jan

      ;

      Jurickova, Katarina

      ;

      Magner, Martin

      ;

      Sikora, Jakub

      2024

      ,

      Springer

      ,

      Virchows Archiv

      ,

      484

      (1)

      Despite the adenoids are regularly removed in patients with mucopolysaccharidoses (MPS), the underlying tissue and cellular pathologies remain understudied. We characterized an (immuno)histopathologic and ultrastructural ...

    • A Fast HPLC/UV Method for Determination of Ketoprofen in Cellular Media 

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      open access

      vydavatelská verze

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      Vozniuk, Oleksandra

      ;

      Kejík, Zdeněk

      ;

      Veselá, Kateřina

      ;

      Skaličková, Markéta

      ;

      Novotný, Petr

      ;

      Hromádka, Róbert

      ;

      Hajduch, Jan

      ;

      Martásek, Pavel

      ;

      Jakubek, Milan

      2024

      ,

      Wiley - V C H Verlag GmbH & Co. KGaA

      ,

      ChemistryOpen

      ,

      13

      (3)

      A simple, sensitive and quick HPLC method was developed for the determination of ketoprofen in cell culture media (EMEM, DMEM, RPMI). Separation was performed using a gradient on the C18 column with a mobile phase of ...

    • LysoGb3 quantification facilitates phenotypic categorization of Fabry disease patients: Insights gained by a novel MS/MS method 

      původní článek

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      vydavatelská verze

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      Kuchař, Ladislav

      ;

      Berná, Linda

      ;

      Poupětová, Helena

      ;

      Ledvinová, Jana

      ;

      Růžička, Petr

      ;

      Dostálová, Gabriela

      ;

      Reichmannová, Stella

      ;

      Asfaw, Befekadu

      ;

      Linhart, Aleš

      ;

      Sikora, Jakub

      2024

      ,

      Elsevier BV

      ,

      Clinica Chimica Acta

      ,

      561

      (July)

      Background: Fabry disease (FD) is an X-linked lysosomal storage disease resulting from pathogenic variants in the GLA gene coding alpha-galactosidase A (AGAL) and cleaving terminal alpha-linked galactose. Globotriaosylceramide ...

    • Changes of Anaerobic Power and Lactate Concentration following Intense Glycolytic Efforts in Elite and Sub-Elite 400-meter Sprinters 

      původní článek

      open access

      vydavatelská verze

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      Mastalerz, Andrzej

      ;

      Johne, Monika

      ;

      Mroz, Anna

      ;

      Bojarczuk, Aleksandra

      ;

      Šťastný, Petr

      ;

      Petr, Miroslav

      ;

      Kolinger, Dominik

      ;

      Pisz, Anna

      ;

      Vostatková, Pavlína

      ;

      Maculewicz, Ewelina

      2024

      ,

      Journal of Human Kinetics

      ,

      91

      (April Spec Issue)

      400-m races are based on anaerobic energy metabolism, they induce significant muscle fatigue, muscle fiber damage, and high blood lactate (LA) concentration. Despite extensive research on sprint training, our understanding ...

    • The Czech National MS Registry (ReMuS): Data trends in multiple sclerosis patients whose first disease-modifying therapies were initiated from 2013 to 2021 

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      Šťastná, Dominika

      ;

      Drahota, Jiří

      ;

      Lauer, Michal

      ;

      Mazouchová, Aneta

      ;

      Meňkyová, Ingrid

      ;

      Adámková, Jana

      ;

      Ampapa, Radek

      ;

      Dufek, Michal

      ;

      Grunermelova, Marketa

      ;

      Hradilek, Pavel

      ;

      Kubala Havrdová, Eva

      ;

      Mareš, Jan

      ;

      Martínková, Alena

      ;

      Pavelek, Zbyšek

      ;

      Peterka, Marek

      ;

      Recmanová, Eva

      ;

      Ročková, Petra

      ;

      Štětkářová, Ivana

      ;

      Štourač, Pavel

      ;

      Vachová, Marta

      ;

      Horáková, Dana

      2024

      ,

      Palacký University

      ,

      Biomedical Papers

      ,

      168

      (3)

      AIMS: Multiple sclerosis treatment strategies are changing in the Czech Republic. According to data from 2013-2021, the proportion of patients starting high-efficacy disease-modifying therapies is increasing. In this survey, ...

    • Structural and microstructural predictors of cognitive decline in deep brain stimulation of subthalamic nucleus in Parkinson's disease 

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      Filip, Pavel

      ;

      Mana, Josef

      ;

      Lasica, Andrej

      ;

      Keller, Jiří

      ;

      Urgošík, Dušan

      ;

      May, Jaromír

      ;

      Müller, Karsten

      ;

      Jech, Robert

      ;

      Bezdíček, Ondřej

      ;

      Růžička, Filip

      2024

      ,

      Elsevier

      ,

      NeuroImage. Clinical

      ,

      42

      (May)

      BACKGROUND AND OBJECTIVES: The intricate relationship between deep brain stimulation (DBS) in Parkinson's disease (PD) and cognitive impairment has lately garnered substantial attention. The presented study evaluated pre-DBS ...

    • Naturalizing Nous ? Theophrastus on Nous, Nature, and Motion 

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      Falcon, Andrea

      ;

      Roreitner, Robert

      2024

      ,

      Phronesis

      ,

      69

      (4)

      There is prima facie evidence that Theophrastus naturalized nous to the extent that he spoke of it in naturalizing terms. But our evidence also suggests that Theophrastus accepted the reasons Aristotle had for excluding ...

    • Amiodarone but not propafenone impairs bioenergetics and autophagy of human myocardial cells 

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      Krajčová, Adéla

      ;

      Němcová, Vlasta

      ;

      Halačová, Milada

      ;

      Waldauf, Petr

      ;

      Balík, Martin

      ;

      Duška, František

      2023

      ,

      Toxicology and Applied Pharmacology

      ,

      477

      (October)

      Cardiac and extra-cardiac side effects of common antiarrhythmic agents might be related to drug-induced mitochondrial dysfunction. Supratherapeutic doses of amiodarone have been shown to impair mitochondria in animal ...

    • Small nucleolar RNA expression profiles: A potential prognostic biomarker for non-viral Hepatocellular carcinoma 

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      Mallela, Venkata Ramana

      ;

      Kasi, Phanindra Babu

      ;

      Shetti, Dattatrya

      ;

      Trailin, Andriy

      ;

      Červenková, Lenka

      ;

      Pálek, Richard

      ;

      Daum, Ondřej

      ;

      Liška, Václav

      ;

      Hemminki, Kari Jussi

      ;

      Ambrożkiewicz, Filip

      2024

      ,

      Non-coding RNA Research

      ,

      9

      (4)

      Hepatocellular carcinoma (HCC) is a challenging cancer with high mortality rates, limited predictability, and a lack of effective prognostic indicators. The relationship between small nucleolar RNAs (snoRNAs) and HCC is ...

    • Restituce nacisty uloupeného umění v České republice 

      Restitution of Nazi-Looted Art in the Czech Republic

      přednáška

      open access

      draft

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      Löbling, Zuzana

      2024

      Podobně jako sousední země je i Česká republika zasažena problematikou nacisty uloupeného umění. Nicméně vzhledem ke specifickélokální situaci musela najít vhodný způsob, jak se s touto problematikou vypořádat. První ...

    • The Struggle for Justice: Post-WWII Restitution of Richard Morawetz’ Art Collection 

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      embargo

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      Löbling, Zuzana

      2024

      This presentation shows the post-WWII restitution efforts for the significant art collection of Richard Morawetz, which was deposited in the the National Gallery Prague in 1939. Following the family's escape from Czechoslovakia ...