Repozitář publikační činnosti UK: Recent submissions
Now showing items 1241-1260 of 2225
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Interesting facts: holistic interviews on children’s nonfiction engagement
original article
embargoed access
published version
2024
,Language and Education
,38
(4)
Nonfiction has long been left out of the discourse on literacy and little is known about the affective experiences that children seek when they choose to engage with facts via reading and otherwise. We have conducted an ...
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Memory Traces, Phenomenology and the Simulationist vs Causal Theory Dispute
original article
open access
published version
2024
,Wydawnictwo Naukowe Uniwersytetu Szczecińskiego
,Analiza i Egzystencja
,65
(1)
Philosophy of memory is a hot topic in the cognitive sciences and philosophy of mind. This work examines the dispute between simulations and causal theories of memory by means of an examination of the feeling of familiarity ...
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Mitochondrial HER2 stimulates respiration and promotes tumorigenicity
original article
open access
published version
2024
,Blackwell Science
,European Journal of Clinical Investigation
,54
(6)
Background: Amplification of HER2, a receptor tyrosine kinase and a breast cancer-linked oncogene, is associated with aggressive disease. HER2 protein is localised mostly at the cell membrane, but a fraction translocates ...
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Specifically Targeting Capture and Photoinactivation of Viruses through Phosphatidylcholine-Ganglioside Vesicles with Photosensitizer
original article
open access
published version
2024
,JACS Au
,4
(8)
Herein, we performed a simple virus capture and photoinactivation procedure using visible light on phosphatidylcholine vesicles. L-α-Phosphatidylcholine vesicles were enriched by viral receptors, GT1b gangliosides, and the ...
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Educational inequalities in cervical cancer screening participation in 24 European countries
original article
open access
published version
2024
,Public Health
,233
(August)
OBJECTIVES: Cervical cancer screening (CCS) is an important public health measure for early detection of cervical cancer and prevents a large proportion of cervical cancer deaths. However, participation in CCS is relatively ...
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Die Lipnitzer Bibel von 1421 als Zeuge eines "Heiligen Krieges"
The Lipnice Bible of 1421 as a Witness of a "Holy War"
chapter in a collective monograph
open access
published version
2024
,Wien
,Böhlau Verlag
,Herzog Albrecht V. und die Auswirkungen der Hussitenkriege
Die Studie untersucht einen lateinischen biblischen Kodex, bekannt als die Lipnicer Bibel, die 1421 auf der Burg Lipnice in Böhmen geschrieben wurde. Sie stellt den Kodex in den weiteren Kontext der Hussitenkriege, der ...
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Democracy and Institutional Change in Times of Crises in Latin America
original article
open access
published version
2024
,Journal of Politics in Latin America
,16
(1)
Latin American democracies have gone through a series of perfect storms over the recent years. In what ways have these challenges transformed the institutional infrastructure of democracy? How have institutional reforms ...
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Kapitoly ke kreativním hudebním činnostem
Chapters on Creative Music Education
schoolbook (tertiary education)
open access
published version
2024
,Praha
,Univerzita Karlova, Pedagogická fakulta
Vysokoškolská učebnice Kapitoly ke kreativním hudebním činnostem je publikačním výstupem projektu Hudební mozaika aneb Kreativní interakce jako východisko rozvoje hudební kreativity v komplexu hudebních činností, který byl ...
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Characterization of STING agonist-induced monocyte cell death reveals combination of apoptosis, pyroptosis and caspase 8 activation
abstract in conference proceedings
open access
accepted version
2024
,Hoboken
,Wiley-VCH
,European Journal of Immunology
,54
(S1)
The cyclic-GMP-AMP synthase - stimulator of interferon genes (cGAS-STING) pathway senses double-stranded DNA in cytoplasm, a signal of invading pathogens or cell damage. The activation of the cGAS-STING pathway induces ...
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Correlation of genotype, phenotype and mitochondrial metabolism of patients with Friedreich's ataxia with the aim of implementing innovative therapies
poster
restricted access
accepted version
2022
Title: Presentation of a cohort of 40 Czech and Slovak patients with Friedreich's ataxia with the aim of introducing innovative therapiesBackground and objectives: Friedreich's ataxia (FA) is an autosomal recessive inherited ...
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The Marital Fertility of Men and Women in Czechia before the First Demographic Transition and in the Current Population
original article
open access
published version
2024
,Demografie
,66
(2)
The aim of this study is to analyse the changes in the marital fertility of men and women in Czechia before the first demographic transition (data obtained by excerpting the parish registers of Škvorec manor in the years ...
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The fertility timing gap: the intended and real timing of childbirth
original article
open access
published version
2024
,Journal of Biosocial Science
,56
(3)
The fertility gap, which indicates the difference between the planned and actual number of children born, can be explained by the shift in parenthood to older ages and is associated with the non-attainment of one's intended ...
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Why and how to construct an epistemic justification of machine learning?
original article
embargoed access
published version
2024
,Synthese
,204
(2)
Consider a set of shuffled observations drawn from a fixed probability distribution over some instance domain. What enables learning of inductive generalizations which proceed from such a set of observations? The scenario ...
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Targeted Protein Degradation (TPD) for Immunotherapy: Understanding Proteolysis Targeting Chimera-Driven Ubiquitin-Proteasome Interactions
summarizing article
open access
published version
2024
,American Chemical Society
,Bioconjugate Chemistry
,35
(8)
Targeted protein degradation or TPD, is rapidly emerging as a treatment that utilizes small molecules to degrade proteins that cause diseases. TPD allows for the selective removal of disease-causing proteins, including ...
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Germline pathogenic variants in the MRE11, RAD50, and NBN (MRN) genes in cancer predisposition: A systematic review and meta-analysis
original article
open access
published version
2024
,Wiley-Liss
,International Journal of Cancer
,155
(9)
The MRE11, RAD50, and NBN genes encode the MRN complex sensing DNA breaks and directing their repair. While carriers of biallelic germline pathogenic variants (gPV) develop rare chromosomal instability syndromes, the cancer ...
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Loss of ADAR1 protein induces changes in small RNA landscape in hepatocytes
original article
open access
published version
2024
,RNA
,30
(9)
In recent years, numerous evidence has been accumulated about the extent of A-to-I editing in human RNAs and the key role ADAR1 plays in the cellular editing machinery. It has been shown that A-to-I editing occurrence and ...
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Educate, not kill: treating cancer without triggering its defenses
original article
open access
published version
2024
,Elsevier Ltd.
,Trends in Molecular Medicine
,30
(7)
Traditionally, anticancer therapies focus on restraining uncontrolled proliferation. However, these cytotoxic therapies expose cancer cells to direct killing, instigating the process of natural selection favoring survival ...
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Suppression of the growth and metastasis of mouse melanoma by Taenia crassiceps and Mesocestoides corti tapeworms
original article
open access
published version
2024
,Frontiers Media SA
,Frontiers in Immunology
,15
(20 March 2024)
Cancer is still one of the leading causes of death, with an estimated 19.3 million new cases every year. Our paper presents the tumor-suppressing effect of Taenia crassiceps and Mesocestoides corti on B16F10 melanoma, the ...
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Sand fly blood meal volumes and their relation to female body weight under experimental conditions
original article
open access
published version
2024
,Parasites & Vectors
,17
(1)
Background Sand fly females require a blood meal to develop eggs. The size of the blood meal is crucial for fecundity and affects the dose of pathogens acquired by females when feeding on infected hosts or during experimental ...
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Outcomes Of Patients With Myocardial Infarction And Cardiogenic Shock Treated With Culprit Vessel-Only Versus Multivessel Primary PCI
original article
open access
published version
2024
,Hellenic Journal of Cardiology
,76
(MAR-APR)
INTRODUCTION AND OBJECTIVES: Multivessel primary percutaneous coronary intervention (pPCI) is still often used in patients with ST-elevation myocardial infarction (STEMI) and cardiogenic shock (CS). The study aimed to ...
