Repozitář publikační činnosti UK: Recent submissions
Now showing items 1361-1380 of 2164
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Validated WGS and WES protocols proved saliva-derived gDNA as an equivalent to blood-derived gDNA for clinical and population genomic analyses
original article
open access
published version
2024
,BioMed Central
,BMC Genomics
,25
(1)
Background: Whole exome sequencing (WES) and whole genome sequencing (WGS) have become standard methods in human clinical diagnostics as well as in population genomics (POPGEN). Blood-derived genomic DNA (gDNA) is routinely ...
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STING agonist induced-monocyte death combines apoptosis, pyroptosis and caspase 8 activation
abstract in conference proceedings
open access
accepted version
2024
,Nizozemsko
,TOLL 2024 Road to translation
The cyclic-GMP-AMP synthase - stimulator of interferon genes (cGAS-STING) pathway isimportant for recognition of double-stranded DNA, a marker of infection or cell damage. ThecGAS-STING pathway activation leads to production ...
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DNA from BK polyomavirus is sensed during infection of reservoir cells via cGAS-STING pathway
abstract in conference proceedings
open access
accepted version
2024
,Nizozemsko
,TOLL 2024 Road to translation
Human polyomaviruses (HPyVs) include 14 species that cause primary asymptomatic infections after which the virus persists in the host by a mechanism that is not well understood. Reactivation of the infection in immunosuppressed ...
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HBV-induced microenvironment reduces pDC response to TLR9 stimulation
abstract in conference proceedings
open access
accepted version
2024
,Nizozemsko
,TOLL 2024 Road to translation
Hepatitis B virus (HBV) is a non-cytopathogenic virus with DNA genome. It causes an acute hepatitis that may develop into chronic hepatitis B, liver cirrhosis and hepatocellular carcinoma. HBV is described as "stealth ...
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Increased burden of rare protein-truncating variants in constrained, brain-specific and synaptic genes in extremely impulsively violent males with antisocial personality disorder
original article
open access
published version
2024
,Blackwell Pub.
,Genes, Brain and Behavior
,23
(1)
The genetic correlates of extreme impulsive violence are poorly understood, and there have been few studies that have characterized a large group of affected individuals both clinically and genetically. We performed whole ...
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Metabolomic analysis of the human placenta reveals perturbations in amino acids, purine metabolites, and small organic acids in spontaneous preterm birth
original article
open access
published version
2024
,EXCLI Journal
,23
(February)
Spontaneous preterm delivery presents one of the most complex challenges in obstetrics and is a leading cause of perinatal morbidity and mortality. Although it is a common endpoint for multiple pathological processes, the ...
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Pathological shifts in tryptophan metabolism in human term placenta exposed to LPS or poly I:C
original article
open access
published version
2024
,Biology of Reproduction
,110
(4)
Maternal immune activation during pregnancy is a risk factor for offspring neuropsychiatric disorders. Among the mechanistic pathways by which maternal inflammation can affect fetal brain development and programming, those ...
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Digitisation and EU Competition Law - Time to Rethink the Basics?
original article
open access
published version
2024
,The Lawyer Quarterly
,14
(1)
The article reflects on the question to what extent the complex reality of online platforms undermines the foundations of EU competition law, which are the presuppositions of neoclassical economics and the targeting of ...
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The Europeanisation of Clean Sport: How the Council of Europe and the European Union Shape the Proportionality of Ineligibility in the World Anti-Doping Code
chapter in a collective monograph
open access
published version
2024
,Oxford
,Hart Publishing
,The European Roots of the Lex Sportiva: How Europe Rules Global Sport
This chapter examines the role of the Council of Europe (CoE) and the European Union (EU) in shaping the proportionality of ineligibility for doping in the World Anti-Doping Code (WADC). It employs an empirical study of ...
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Proportionality during Times of Crisis: Precautionary Application of Proportionality Analysis in the Judicial Review of Emergency Measures
original article
open access
published version
2024
,European Constitutional Law Review
,20
(1)
The need for a standard of review even during times of crisis - proportionality analysis as the ideal and universally applicable standard of review - the problem of excessive stringency of proportionality analysis during ...
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ASSESSMENT OF PHYSICAL CAPACITY LEVEL IN RECREATIONAL ATHLETES
original article
restricted access
published version
2023
,Journal of Kinesiology and Exercise Sciences
,33
(104)
Introduction: In the majority of the available source materials, research on the level of physical capacity of athletes concernsmembers of sports clubs and national teams, in a word, professional athletes. Does this mean ...
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Simultaneous PCR detection of Paenibacillus larvae targeting insertion sequence IS256 and Melissococcus plutonius targeting pMP1 plasmid from hive specimens
original article
open access
accepted version
2024
,Folia Microbiologica
,69
(2)
Paenibacillus larvae and Melissococcus plutonius represent the most threatening bacterial diseases of honeybee (Apis mellifera)-American and European foulbrood, respectively. For efficient control of those diseases, rapid ...
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Lokálne politiky integrácie migrantov a ich štrukturálne mechanizmy
Local Migrant Integration Policies and Their Structural Mechanisms
collective monograph
open access
published version
2023
,Bratislava
,Univerzita Komenského v Bratislave
Publikace se zabývá integrací migrantů v České republice, na Slovensku, v Belgii (Vlámsku) a v Německu (Bavorskou) s cílem přiblížit kontext integrace migrantů v jednotlivých zemích a najít příležitosti pro vzájemné učení ...
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Determinants of self-rated health among highly educated Ukrainian women refugees in Czechia: analysis based on cross-sectional study in 2022
original article
open access
published version
2024
,BMC Women's Health
,24
(1)
Background: Russia's military aggression against Ukraine set in motion a large number of refugees. Considerable amount of them came and stayed in Czechia. Refugees represent special vulnerable individuals often affected ...
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Bibliografie prací Blanky Zilynské
Bibliography of works of Blanka Zilynská
summarizing article
open access
published version
2016
,Acta Universitatis Carolinae. Historia Universitatis Carolinae Pragensis
,56
(1)
Středověk v historii Univerzity Karlovy, Jan Hus a dějiny Univerzity Karlovy ve 20. století jsou témata, na která se specializuje Blanka Zilynská a to se odráží v jejích publikacích. Bibliografie je řazena chronologicky, ...
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Die Beendigung der Konfessionalisierung der Prager Universität an der Wende von den 1450er zu den 1460er Jahren am Beispiel des Schicksals aktiver katholischer Magister
Završení konfesionalizace pražské univerzity na přelomuv50. a 60. let 15. století na příkladu osudu aktivních katolických mistrů
Culmination of the Confessionalization of the University of Prague at the End of the 1450s and Beginning of the 1460s in the Example of the Fate of Active Catholic Master
original article
open access
published version
2021
,Acta Universitatis Carolinae. Historia Universitatis Carolinae Pragensis
,60/2020
(1)
Der Artikel konzentriert sich auf eine Gruppe von Magistern, die dem katholischen Verwalter Hilarius Litoměřický treu ergeben waren, der Ende der 1450er Jahre versuchte, die Kontrolle über die Universität zu übernehmen. ...
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Zděněk Kalista mezi historiografií a literaturou, 24. září 2020, Benátky nad Jizerou
Zdeněk Kalista between historiography and literature, 24. September 2020, Benátky nad Jizerou
other article
open access
published version
2020
,AUC Historia Universitatis Carolinae Pragensis [online]
,2020
(60/2)
Zpráva o konferenci věnvané historikovi Zdeňku Kalistovi, která se uskutečnila 24. září 2020 v Benátkách nad Jizerou.
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Civil society organisations and labour market integration: barriers and enablers in seven European countries
chapter in a monograph
restricted access
published version
2023
,Bristol
,Bristol University Press
,Migrants and Refugees in Europe: Work Integration in Comparative Perspective
This chapter discusses the role of civil society organisations (CSOs) in the labour market integration of migrants, refugees and asylum seekers (MRAs) in the selected countries addressed by the book. It examines the positions ...
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Turistický diskurs prizmatem narativních figur: Václav Havel jako ikona boje proti komunismu
The Discourse of Tourism through Narrative Figures: Václav Havel as an Icon of the Fight against Communism
original article
open access
published version
2021
,Lidé města / Urban People
,23
(1)
Tématem studie jsou vypravěčské strategie, které uplatňujeme v turistickém diskurzu, když návštěvníkům Prahy přibližujeme postavu Václava Havla a jeho prostřednictvím i vhled do života v Československu v době tzv. komunismu. ...
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Strategie zvyšování reprodukovatelnosti kódování v kvalitativním výzkumu pomocí programu Requal
A Strategy for Increasing Coding Reproducibility in Qualitative Research Using Requal
Summary research report
open access
published version
2023
,Praha
,Technologická agentura ČR
Zpráva shrnuje výsledky řešení projektu a ukazuje, jak lze pomocí porgramu Requal zvýšit reprodukovatelnost kvalitativního výzkumu, přesněji transparenci a reflexivitu kódování kvalitativních dat.
