Repozitář publikační činnosti UK: Recent submissions
Now showing items 1641-1660 of 2160
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Direct 16S/18S rRNA Gene PCR Followed by Sanger Sequencing as a Clinical Diagnostic Tool for Detection of Bacterial and Fungal Infections: a Systematic Review and Meta-Analysis
summarizing article
open access
published version
2023
,Journal of Clinical Microbiology
,61
(9)
rRNA gene Sanger sequencing is being used for the identification of cultured pathogens. A new diagnostic approach is sequencing of uncultured samples by using the commercial DNA extraction and sequencing platform SepsiTest ...
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Faecal bacteriome and metabolome profiles associated with decreased mucosal inflammatory activity upon anti-TNF therapy in paediatric Crohn's disease
original article
open access
published version
2024
,Oxford University Press
,Journal of Crohn's and Colitis
,18
(1)
BACKGROUND AND AIMS: Treatment by anti-TNFα antibodies (anti-TNF) changes the dysbiotic faecal bacteriome in Crohn's disease (CD). However, it is not known whether these changes are due to decreasing mucosal inflammatory ...
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Heterogeneous response to TGF-β1/3 isoforms in fibroblasts of different origins: implications for wound healing and tumorigenesis
original article
open access
published version
2023
,Histochemistry and Cell Biology
,160
(6)
Identification of therapeutic targets for treating fibrotic diseases and cancer remains challenging. Our study aimed to investigate the effects of TGF-β1 and TGF-β3 on myofibroblast differentiation and extracellular matrix ...
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Population-Attributable Fractions of Personal Comorbidities for Liver, Gallbladder, and Bile Duct Cancers
original article
open access
published version
2023
,Cancers
,15
(12)
Simple Summary Liver cancer is often used as a general term for cancers of the liver (hepatocellular carcinoma, HCC), the gallbladder, and the bile ducts. The well-known risk factors are alcohol and viral hepatitis, but ...
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Association of lncRNA and transcriptome intersections with response to targeted therapy in metastatic renal cell carcinoma
original article
open access
published version
2023
,Oncology Letters
,26
(3)
Long non-coding RNAs (lncRNAs) serve an important role in cancer progression and may be used as efficient molecular biomarkers. The present study aimed to identify lncRNAs associated with the response to the receptor ...
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A Fecal MicroRNA Signature by Small RNA Sequencing Accurately Distinguishes Colorectal Cancers: Results From a Multicenter Study
original article
open access
published version
2023
,Gastroenterology
,165
(3)
BACKGROUND & AIMS: Fecal tests currently used for colorectal cancer (CRC) screening show limited accuracy in detecting early tumors or precancerous lesions. In this respect, we comprehensively evaluated stool microRNA ...
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miRNA and lncRNA as Potential Tissue Biomarkers in Hepatocellular Carcinoma
summarizing article
open access
published version
2024
,Non-coding RNA Research
,9
(1)
Hepatocellular carcinoma (HCC) is primary liver cancer, frequently diagnosed at advanced stages with limited therapeutic options. MicroRNAs (miRNAs) regulate target gene expression and through inhibitory competitive binding ...
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Serious Immune-related Adverse Events Are Associated With Greater Efficacy of Nivolumab Therapy Against Non-small Cell Lung Cancer
original article
open access
published version
2023
,In Vivo
,37
(5)
BACKGROUND/AIM: The aim of this study was to investigate possible association between adverse events of nivolumab therapy and the effectiveness of treatment in patients with non-small cell lung cancer (NSCLC). Focusing on ...
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Branchioma with a nested/organoid morphology: molecular profiling of a distinctive potentially misleading variant and reappraisal of potential relationship to CD34-positive/Rb1-deficient tumors of the neck
original article
open access
published version
2023
,Virchows Archiv
,483
(4)
Branchioma (previously called ectopic hamartomatous thymoma, branchial anlage mixed tumor, or thymic anlage tumor) is a rare lower neck lesion with an adult male predominance and an uncertain histogenesis. Except for 4 ...
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Prognostic potential of whole exome sequencing in the clinical management of metachronous colorectal cancer liver metastases
original article
open access
published version
2023
,Cancer Cell International
,23
(1)
Background: Colorectal cancer is a highly prevalent and deadly. The most common metastatic site is the liver. We performed a whole exome sequencing analysis of a series of metachronous colorectal cancer liver metastases ...
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Využití tepové frekvence k optimalizaci rozvoje vytrvalosti
popular article
embargoed access
published version
2023
,Pádler : vodácký magazín
,8
(4)
Článek seznamuje čtenáře s možnostmi využití tepové frekvence v kondičním i speciálním tréninku kanoistů.
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Morphology of canoe slalom and canoe sprint female competitors
poster
embargoed access
published version
2023
This poster presents a comparison of anthropometric and body composition parameters between female performance athletes in canoe slalom and canoe sprint.
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Morphology Differences Between Elite C1 and K1 Canoe Slalom Competitors
poster
embargoed access
accepted version
2022
Introduction: Anthropometric and strength parameters are important factors of the white water slalom performance. However, differences between kayak (K1) and canoe (C1) category are still unknown. The aim of this study is ...
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Discovery of Small Molecule Activators of NRF1 Transcriptional Activity Preventing Protein Aggregation
abstract in conference proceedings
open access
accepted version
2023
The intracellular accumulation of abnormal proteins exceeding their degradation can cause imbalance in proteostasis resulting in proteotoxic stress that leads to severe pathological stages. This state relates to proteasome ...
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Výživové suplementace pro kanoistické sporty
popular article
embargoed access
accepted version
2022
,Pádler : vodácký magazín
,7
(3)
Článek navrhuje konkrétní doplňky výživy pro výkonnostní a vrcholové kanoisty. Je součástí čtyřdílné série popularizujících článků směřujících k vyšší výkonnosti nejen vrcholových sportovců.
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Zimní kondiční příprava
popular article
embargoed access
accepted version
2022
,Pádler
,7
(4)
V článku je představena modelová zimní kondiční příprava pro sportovce kanoistických disciplín.
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Psychologická příprava
popular article
embargoed access
accepted version
2022
,Pádler : vodácký magazín
,7
(2)
Článek se zabývá psychologickou přípravou ve vodním slalomu. Navrhuje vhodné metoda rozvoje psychických determinant výkonu ve vodním slalomu i dalších kanoistických sportech.
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‚I will not be a mere wreath layer!‘ Analysis of the presidential refusal to appoint cabinet ministers in the Czech Republic
original article
embargoed access
published version
2023
,Acta Politologica
,2023
(15)
The discrepancy between the constitutionally defined and actual exercise of the power ofstate institutions has been widely discussed within European political science. The adop- tion of direct presidential elections in the ...
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The Dynamics of Postnominal Adjectives in Middle English
original article
open access
published version
2022
,Anglica. An International Journal of English Studies
,31
(2)
Middle English was a period of transition between the free word order of Old English, with functional variation of adjective form and position with respect to the head noun, and the fixed prenominal placement of single ...
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Embodying Agonism in Lucy Kirkwood’s Mosquitoes and The Welkin
original article
open access
published version
2022
,Litteraria Pragensia: Studies in Literature and Culture
,32
(63)
Rooted in Chantal Mouffe's conceptualisation of agonistic pluralism and Jacques Rancière's work on dissensus, this article analyses the debate scenes of British playwright Lucy Kirkwood's plays: Mosquitoes (2017) and The ...
