Now showing items 21-40 of 1840

    • Serum bilirubin concentrations and their association with clinical and radiological outcomes in multiple sclerosis: A large cohort study 

      original article

      open access

      published version

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      Uher, Tomáš

      ;

      Kleinová, Pavlína

      ;

      Woronyczová, Jana

      ;

      Štěpánek, Lubomír

      ;

      Vaněčková, Manuela

      ;

      Krásenský, Jan

      ;

      Cífková, Renata

      ;

      Horáková, Dana

      ;

      Kubala Havrdová, Eva

      ;

      Hoskovec, David

      ;

      Leníček, Martin

      ;

      Vítek, Libor

      2026

      ,

      Elsevier España

      ,

      Annals of Hepatology

      ,

      31

      (1)

      Introduction and Objectives: Bilirubin is negatively associated with neurodegenerative diseases, including multiple sclerosis (MS). Since previous studies were small or did not evaluate all diagnostic aspects, the objective ...

    • Ruthenium-enhanced curcumin derivatives target tumor growth and cancer-related inflammation in head and neck cancer models 

      original article

      open access

      published version

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      Veselá, Kateřina

      ;

      Tatar, Ameneh

      ;

      Kejík, Zdeněk

      ;

      Abramenko, Nikita

      ;

      Kaplánek, Robert

      ;

      Babula, Petr

      ;

      Kučnirová, Kateřina

      ;

      Hajduch, Jan

      ;

      Martásek, Pavel

      ;

      Jakubek, Milan

      2025

      ,

      Frontiers Media SA

      ,

      Frontiers in Oncology

      ,

      15

      (December)

      Introduction Head and neck cancers (HNC) remain a significant clinical challenge, particularly due to their association with chronic inflammation triggered by tobacco carcinogens and human papillomavirus (HPV) infection. ...

    • Exploring the full spectrum of reproductive experiences 

      original article

      open access

      published version

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      Slabá, Jitka

      ;

      Jírová, Jitka

      ;

      Šťastná, Anna

      ;

      Kocourková, Jiřina

      2026

      ,

      University of Bamberg Press

      ,

      Journal of Family Research

      ,

      38

      (January 13, 2026)

      Objective: The study examines changes across cohorts in terms of the timing and frequency of the full spectrum of reproductive events and explores whether these reproductive trajectories reflect broader trends towards the ...

    • Targeting tumors and inflammation: A quinoline–chalcone ruthenium complex with therapeutic promise 

      original article

      open access

      published version

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      Veselá, Kateřina

      ;

      Tatar, Ameneh

      ;

      Kejík, Zdeněk

      ;

      Abramenko, Nikita

      ;

      Čejka, Jan

      ;

      Kaplánek, Robert

      ;

      Masařík, Michal

      ;

      Babula, Petr

      ;

      Martásek, Pavel

      ;

      Jakubek, Milan

      2026

      ,

      Elsevier

      ,

      Biomedicine & Pharmacotherapy

      ,

      194

      (January)

      Head and neck cancers remain among the most challenging malignancies to treat and are often linked to lifestyle-related risk factors such as smoking and alcohol consumption. These factors not only initiate tumor development ...

    • Enhancing abdominal wall healing using an oriented polycaprolactone microfibrous scaffold prepared using the fiber drawing method: A rabbit model study 

      original article

      open access

      published version

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      Klusáček Rampichová, Michala

      ;

      Strnadová, Kateřina

      ;

      Plencner, M

      ;

      Stanislav, L

      ;

      Litvinec, A

      ;

      Tonar, Zbyněk

      ;

      Blassová, Tereza

      ;

      Otáhal, M

      ;

      Filová, E

      ;

      Lukáš, D

      ;

      Jenčová, V

      2026

      ,

      Springer-Verlag France

      ,

      Hernia

      ,

      30

      (1)

      PURPOSE: Incisional hernia is a common postoperative complication following abdominal surgery. Despite the use of synthetic meshes, recurrence rates remain high. This study aimed to develop and evaluate a biodegradable, ...

    • Parental decision-making regarding vaccination: the role of preschool enrolment sanctions, family policies and childcare expectation 

      original article

      open access

      published version

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      Hasmanová Marhánková, Jaroslava

      2025

      ,

      Taylor & Francis

      ,

      European Societies

      ,

      27

      (5)

      The Czech Republic exemplifies a country with a mandatory childhood vaccination system. A child who has not completed compulsory vaccinations cannot be admitted to preschool until age 5. This paper discusses this measure's ...

    • Environmental stability of untreated neutral metalliferous mine drainage sludge after 100 years of weathering 

      original article

      open access

      published version

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      Warchulski, Rafal

      ;

      Kupczak, Krzysztof

      ;

      Ettler, Vojtěch

      ;

      Mihaljevič, Martin

      ;

      Krzykawski, Tomasz

      ;

      Sitko, Rafal

      2025

      ,

      Kluwer

      ,

      Environmental Geochemistry and Health

      ,

      47

      (12)

      Untreated neutral metalliferous mine drainage sludge deposited without environmental protection for over a century was studied to assess its long-term stability. The lack of long-term stability data on such untreated sludge ...

    • Silver is immobile in Ag-rich mine waste: Isotopic evidence from anthropogenic soils 

      original article

      open access

      published version

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      Vaňková, Maria

      ;

      Vaněk, Aleš

      ;

      Shalabai, Anastasiia

      ;

      Mihaljevič, Martin

      ;

      Ettler, Vojtěch

      ;

      Racek, Martin

      ;

      Drahota, Petr

      ;

      Fleissig, Petr

      ;

      Vokurková, Petra

      ;

      Zádorova, Tereza

      ;

      Penížek, Vít

      ;

      Hrdlička, Tomáš

      ;

      Mathur, Ryan

      2026

      ,

      Elsevier

      ,

      Journal of Geochemical Exploration

      ,

      282

      (March)

      This study presents silver (Ag) stable isotope ratios (expressed as delta Ag-109) combined with mineralogy and speciation data in Ag-contaminated anthropogenic soils from a historic mining area at Kutna Hora, Czech Republic. ...

    • Mutational landscape of lung adenocarcinoma in Czechia 

      original article

      open access

      published version

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      Ambrożkiewicz, Filip

      ;

      Ali, Esraa

      ;

      Bradová, Martina

      ;

      Slavík, Petr

      ;

      Martínek, Petr

      ;

      Svatoň, Martin

      ;

      Hemminki, Akseli

      ;

      Hemminki, Kari Jussi

      2026

      ,

      Elsevier Inc.

      ,

      Cancer Treatment and Research Communications

      ,

      46

      Limited DNA sequencing data on lung cancer (LC) patients are available from Eastern Europe where male smoking is commonest in Europe. As sequence analysis is the prerequisite for targeted therapy we provide such data from ...

    • Dopady pandemie covidu-19 na vnímání rizika a naplňování péče v rámci různých „světů“ zaměstnanců domova pro seniory 

      Exploring the Effects of the Covid-19 Pandemic on Risk Perception and Care Dynamics Among Staff in Residential Homes for Older Adults

      original article

      open access

      published version

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      Hasmanová Marhánková, Jaroslava

      ;

      Jandová, Martina

      2025

      ,

      Sociologický ústav AV ČR v.v.i.

      ,

      Sociologický časopis / Czech Sociological Review

      Tato studie si klade za cíl rozšířit porozumění dopadu pandemie Covid-19 a souvisejících opatření na fungování zařízení dlouhodobé péče pro starší osoby a na zaměstnance pracující v těchto institucích. Článek prezentuje ...

    • Vector competence of sand flies to Leishmania parasites and Toscana virus 

      abstract in conference proceedings

      open access

      accepted version

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      Volf, Petr

      2025

      ,

      9th Society for Vector Ecology (SOVE) International Congress: Connecting Vector Science Globally - Abstract Book

      Phlebotomine sand flies transmit a range of human pathogens, including Leishmania parasites and viruses such as Toscana virus (TOSV). Recent studies have shown that Phlebotomus tobbi and P. sergenti, two species widespread ...

    • Dynamic shifts in trophoblast nucleos(t)ide metabolism, transport, and adenosine signaling during gestation and preterm birth 

      original article

      open access

      published version

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      Ali, Mohammed

      ;

      Adler, Mariia

      ;

      Libra, Antonín

      ;

      Vokřál, Ivan

      ;

      Karahoda, Rona

      ;

      Cífková, Eva

      ;

      Lísa, Miroslav

      ;

      Tomek, Jakub

      ;

      Novotná, Magdaléna

      ;

      Štaud, František

      ;

      Červený, Lukáš

      2025

      ,

      Springer Nature

      ,

      Scientific Reports

      ,

      15

      (1)

      Nucleos(t)ides are essential for DNA/RNA synthesis, energy metabolism, and signaling, yet their roles in placental development remain poorly understood. The placenta undergoes dynamic metabolic adaptations throughout ...

    • Mezi bolestí a nedůvěrou: Sociální kontext sporných onemocnění na příkladu fibromyalgie 

      Between Pain and Distrust: The Social Context of Contested Illnesses Viewed through the Case of Fibromyalgia

      original article

      open access

      published version

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      Králová, Josefína

      ;

      Hasmanová Marhánková, Jaroslava

      2025

      ,

      Sociologický ústav SAV

      ,

      Sociológia

      ,

      57

      (5)

      This study explores the illness narratives of individuals diagnosed with fibromyalgia, focusing on how the condition's invisibility and the challenges surrounding the diagnostic process shape patients' everyday experiences ...

    • Protestantské konfesijní školy v českých zemích z kvantitativního hlediska 

      A Quantitative Analysis of Protestant Confessional Schools in the Czech Lands

      original article

      open access

      published version

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      Nešpor, Zdeněk

      2025

      ,

      Národní pedagogické muzeum a knihovna J. A. Komenského

      ,

      Historia scholastica

      ,

      11

      (2)

      Autor analyzuje konfesionální protestantské školy v českých zemích, zakládané v "dlouhém" 19. století a v některých případech trvající do století 20., z kvantitativního hlediska: kde, kdy a proč byly tyto školy zřizovány, ...

    • Anticoronavirus Isoquinoline Alkaloids: Unraveling the Secrets of Their Structure-Activity Relationship 

      original article

      open access

      published version

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      Šafratová, Marcela

      ;

      Chen, Yu-Li

      ;

      Hošťálková, Anna

      ;

      Chlebek, Jakub

      ;

      Hsieh, Chung-Fan

      ;

      Chen, Bing-Hung

      ;

      Cahlíková, Lucie

      ;

      Kosturko, Štefan

      ;

      Backlund, Anders

      ;

      Horng, Jim-Tong

      ;

      Hwang, Tsong-Long

      ;

      Kořínek, Michal

      2025

      ,

      Blackwell

      ,

      Influenza and Other Respiratory Viruses

      ,

      19

      (10)

      Background: Natural alkaloids are a structurally diverse class of bioactive compounds with significant therapeutic potential. This study aimed to evaluate the in vitro antiviral activity of various natural alkaloids against ...

    • Non-destructive in vivo tracking of gelatin hydrogels for advancing tissue engineering 

      original article

      open access

      draft

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      Kolouchová, Kristýna

      ;

      Humajová, Jana

      ;

      Matouš, Petr

      ;

      Ritter, Nicole

      ;

      Van Damme, Lana

      ;

      Hovořáková, Mária

      ;

      Pavlíková, Zuzana

      ;

      Dalecká, Linda

      ;

      Steklíková, Klára

      ;

      Zeman, Jan

      ;

      Kučka, Jan

      ;

      Hruby, Martin

      ;

      Groborz, Ondřej

      ;

      Šefc, Luděk

      ;

      Van Vlierberghe, Sandra

      2025

      ,

      Communications Materials

      ,

      6

      (1)

      Photo-crosslinkable gelatin-based hydrogels hold great promise for tissue engineering and regenerative medicine. However, monitoring these hydrogels in vivo remains challenging and limits their further development and ...

    • Ocrelizumab transiently alters microbiota and modulates immune response depending on treatment outcome 

      original article

      open access

      published version

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      Coufal, Stepan

      ;

      Jiraskova Zakostelska, Zuzana

      ;

      Thon, Tomas

      ;

      Roubalova, Radka

      ;

      Kadlečková, Dominika

      ;

      Saláková, Martina

      ;

      Tachezy, Ruth

      ;

      Hrncir, Tomas

      ;

      Kverka, Miloslav

      ;

      Tichá, Veronika

      ;

      Pavelcová, Miluše

      ;

      Kleinová, Pavlína

      ;

      Lízrová Preiningerová, Jana

      ;

      Kovářová, Ivana

      ;

      Kreisinger, Jakub

      ;

      Tlaskalova-Hogenova, Helena

      ;

      Kubala Havrdová, Eva

      2025

      ,

      Cell Press, Elsevier, Inc.

      ,

      iScience

      ,

      28

      (12)

      Multiple sclerosis (MS) is an autoimmune disease characterized by central nervous system atrophy. Microbiota dysbiosis is implicated in MS pathogenesis and treatment outcomes. In our study, we observed microbiota changes ...

    • Running thoughts through music. A musical inflection of the sonic turn in consumer research 

      original article

      open access

      published version

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      Smith, Simon

      2025

      ,

      Sage

      ,

      Marketing Theory

      If it is well established that narrative can be a tool to think with, I propose doing the same, in parallel, with music. My argument follows the drift of the sonic turn, but inflects it by emphasising the processual features ...

    • Comparative Evaluation of Single- and Multi-Delay Arterial Spin Labeling MRI in Preterm Neonates 

      original article

      open access

      published version

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      Prysiazhniuk, Yeva

      ;

      Alexander, Sasha

      ;

      Armindo, Rui Duarte

      ;

      Tong, Elizabeth

      ;

      Yeom, Kristen W

      ;

      Otáhal, Jakub

      ;

      Kynčl, Martin

      ;

      Moseley, Michael

      ;

      Petr, Jan

      ;

      Zhao, Moss Y

      ;

      Steinberg, Gary K

      2025

      ,

      Academic Press

      ,

      NeuroImage

      ,

      321

      (November)

      INTRODUCTION: Preterm neonates are vulnerable to brain injuries from disrupted cerebral blood flow (CBF). Achieving high-quality MRI remains a major challenge in neonatal neuroimaging. Arterial Spin Labeling (ASL) MRI ...

    • Sleep in Functional Motor Disorders: A Case-Control Polysomnographic Study 

      original article

      open access

      published version

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      Nepožitek, Jiří

      ;

      Dostálová, Simona

      ;

      Jirásek, Martin

      ;

      Chaloupková, Gabriela

      ;

      Forejtová, Zuzana

      ;

      Nováková, Lucia

      ;

      Rottová, Veronika

      ;

      Konvičná, Veronika

      ;

      Šonka, Karel

      ;

      Edwards, Mark J

      ;

      Serranová, Tereza

      2026

      ,

      Blackwell Science

      ,

      Journal of Sleep Research

      ,

      E-PUB

      Sleep problems are frequent in functional motor disorders (FMDs). Surprisingly, objective correlates of impaired sleep and its relationship to other comorbidities have been understudied, and no polysomnographic study is ...