Now showing items 341-360 of 1843

    • Choosing from a range of e-sources when planning lessons – a challenge for teachers 

      original article

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      published version

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      Stará, Jana

      ;

      Vodrážková, Alžběta

      2022

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      IARTEM [online]

      ,

      14

      (1)

      In this article, we report on a qualitative exploratory study in a primary school based on observation in classrooms and interviews with teachers. The aim was to find out what e-sources teachers were using during the ...

    • Held back by limited experience, training, and therapeutic confidence: self-perceptions of Czech mental health professionals about addressing paraphilic-related concerns 

      original article

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      Martinec Nováková, Lenka

      ;

      Krejčová, Lucie

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      Potyszová, Kateřina

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      Klapilová, Kateřina

      2025

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      Sexual and Relationship Therapy

      ,

      40

      (1)

      A body of literature shows that a considerable proportion of mental health and social work professionals who are approached by help-seeking people with paraphilic interests find themselves unprepared to respond to these ...

    • Epidemiology and healthcare utilization in motor neuron disease in Czechia 

      original article

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      Kara, Nazli Sila

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      Zouharova, Anna

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      Broulikova, Hana Marie

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      Jarkovsky, Jiri

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      Šlachtová, Lenka

      2025

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      Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

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      26

      (5-6)

      The demographic and epidemiological profile of motor neuron disease (MND) in Czechia remains unknown, highlighting a critical gap; this study aims to examine the epidemiology of MND using population-based data. We conducted ...

    • Memantine Administration Enhances Glutamatergic and GABAergic Pathways in the Human Hippocampus of Alzheimer's Disease Patients 

      original article

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      Fabrik, Ivo

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      Kupčík, Rudolf

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      Fabriková, Daniela

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      Chvojková, Markéta

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      Holubová, Kristína

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      Hakenová, Kristina

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      Horák, Martin

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      Soukup, Jiří

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      Manethová, Monika

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      Rusina, Robert

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      Matěj, Radoslav

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      Ryška, Aleš

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      Soukup, Ondřej

      2025

      ,

      Wiley-VCH-Verl.

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      Proteomics

      ,

      25

      (15)

      One of the traditional treatments in Alzheimer's disease (AD) is administration of memantine, the NMDA receptor antagonist. However, the molecular mechanism of the complex memantine action and the impact on the hippocampal ...

    • Inhibition of Aspartate β-Hydroxylase Enhances Anti-Tumor Immunity 

      original article

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      Johari, Shweta Dilip

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      Krausová, Kateřina

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      Žucha, Barbora

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      Madureira Trufen, Carlos Eduardo

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      Poláková, Ingrid

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      Olsen, Mark

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      Šmahel, Michal

      2025

      ,

      ImmunoTargets and Therapy

      ,

      14

      (July)

      Aspartate β-hydroxylase (ASPH) contributes to carcinogenesis by promoting tumor cell proliferation, migration, and invasion. The enzymatic activity of ASPH can be inhibited by small molecule inhibitors that have been shown ...

    • A post-COVID-19 upsurge in Group A Streptococcus in the Czech Republic was driven by emm1 and emm12 with shared virulence factors 

      original article

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      Štefan, Marek

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      Prasad, Suhanya Veronica

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      Vitkova, Ivana

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      Nycova, Elka

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      Ryšková, Lenka

      ;

      Kucova, Pavla

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      Geigerová, Lenka

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      Vesela, Denisa

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      Balejova, Magda

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      Bartonikova, Natasa

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      Havlinova, Lenka

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      Czyzova, Erika

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      Kubele, Jan

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      Dratvová, Barbora

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      Antušková, Milena

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      Zíková, Jaroslava

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      Brajerová, Marie

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      Nyč, Otakar

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      Dřevínek, Pavel

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      Trojánek, Milan

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      Krůtová, Marcela

      2025

      ,

      Elsevier

      ,

      Journal of Infection and Public Health

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      18

      (10)

      BACKGROUND: In 2023, a significant increase in Streptococcus pyogenes, Group A Streptococcus (GAS) culture positivity was observed in Czech microbiological laboratories. We conducted a multicentre study to obtain epidemiological ...

    • Confinement as a key but overlooked factor controlling erosion rate in loess pipes and tunnels 

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      Vojtíšek, Jan

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      Bruthans, Jiří

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      Weiss, Tomáš

      2025

      ,

      Geomorphology

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      486

      (October)

      Approximately 10 % of the Earth's land surface is covered by loess. The ability of loess to maintain vertical cliffs indicates its considerable strength, but at the same time loess is susceptible to rapid erosion. The ...

    • Native and decellularized porcine vena cava: Histological analysis and in vitro repopulation 

      original article

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      Massaro, Maria Stefania

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      Pálek, Richard

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      Malečková, Anna

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      Grajciarová, Martina

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      Červenková, Lenka

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      Polák, Robert

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      Šarčević, Sima

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      Ševčík, Jan

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      Bolek, Lukáš

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      Tonar, Zbyněk

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      Liška, Václav

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      Moulisová, Vladimíra

      2025

      ,

      Biomaterials Advances

      ,

      177

      (December)

      Current standards in vascular reconstruction imply the use of autologous or synthetic material. Despite being standard, autologous grafts are limited by pathologies already affecting the patient and possible complications ...

    • Metodika analýzy, vykazování a komparace úrovně předčasné úmrtnosti 

      Methodology for analyzing, reporting, and comparing level of premature mortality

      certified methodology

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      Hulíková Tesárková, Klára

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      Dzúrová, Dagmar

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      Kulhánová, Ivana

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      Lustigová, Michala

      2025

      Navržená metodika analýzy, vykazování a komparace úrovně předčasné úmrtnosti vychází z několika bodů klíčových potřeb, které by tato metodika měla splňovat: (1) mezinárodní, meziregionální a časovou srovnatelnost, (2) ...

    • Arterial wall enhancement indicates higher reperfusion rates in non-ruptured aneurysms after endovascular treatment with stent-assisted coiling 

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      Ladenhauf, Valentin

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      Galijasevic, Malik

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      Regodic, Milovan

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      Rass, Verena

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      Freyschlag, Christian

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      Deeg, Johannes

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      Gruber, Leonhard

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      Swoboda, Michael

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      Bochnička, Jakub

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      Mangesius, Stephanie

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      Lenhart, Lukas

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      Gizewski, Elke Ruth

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      Grams, Astrid Ellen

      2025

      ,

      Neuroradiology

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      67

      (9)

      Background and purpose: There are differing results in recent literature concerning aneurysmal wall enhancement (AWE) after endovascular treatment (ET) of intracranial aneurysms (IAs). The aim of this retrospective study ...

    • Consistent summer temperature signals in a latewood blue intensity network from the upper tree line in the Caucasus 

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      Dhyani, Rupesh

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      Martin-Benito, Dario

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      Doğan, Mehmet

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      Kvaratskhelia, Revaz

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      Köse, Nesibe

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      Güner, Hüseyin Tuncay

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      Schneider, Lea

      2025

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      Dendrochronologia

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      92

      (August)

      Climate variability in the Caucasus region significantly influences tree growth in alpine tree line ecotones. However, long-standing human land-use history disrupted the natural equilibrium between montane forests and ...

    • Hostile Environments: Modifying Surfaces to Block Microbial Adhesion and Biofilm Formation 

      summarizing article

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      Wilkinson, Derek

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      Váchová, Libuše

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      Palková, Zdena

      2025

      ,

      Biomolecules

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      15

      (6)

      Since the first observations of biofilm formation by microorganisms on various surfaces more than 50 years ago, it has been shown that most "unicellular" microorganisms prefer to grow in multicellular communities that often ...

    • Developing molecular surveillance of SARS-CoV-2 in the Czech Republic (2021–2022) 

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      Šúri, Timotej

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      Pfeiferová, Lucie

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      Bezdíček, Matěj

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      Svatoň, Jan

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      Hampl, Vladimír

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      Berka, Karel

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      Jiřincová, Helena

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      Lengerová, Martina

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      Kolísko, Martin

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      Nagy, Alexander

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      Tachezy, Ruth

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      Kolář, Michal

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      Pačes, Jan

      2025

      ,

      Springer Nature

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      Scientific Reports

      ,

      15

      (1)

      Molecular surveillance was widely used during the COVID-19 pandemic to detect rapidly emerging variants and monitor the transmission of SARS-CoV-2 within communities. In 2021, the Czech COVID-19 Genomics Consortium (COG-CZ) ...

    • The relationship between food security, fruit and vegetable consumption, and health-related factors in the late COVID-19 pandemic in Czechia: a cross-sectional study 

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      Ohno, Maika

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      Vávra, Jan

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      Jehlička, Petr

      2025

      ,

      BMC Public Health

      ,

      25

      (1)

      Background: Food insecurity is one of the social determinants of health and affects dietary quality and well-being. This study aimed to examine the associations among food insecurity, sociodemographic and economic factors, ...

    • Uncovering agnoprotein interactions with cellular membranes during BKPyV infection in reservoir cells 

      abstract in e-form

      open access

      accepted version

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      Lovtsov, Alexey

      ;

      Huerfano Meneses, Sandra

      2025

      BK polyomavirus (BKPyV), a widespread human virus, causes asymptomatic infectionsthat persist indefinitely. In immunosuppressed patients, particularly kidney transplantrecipients, reactivated viral replication can lead to ...

    • Rezkova věcnost a její techniky 

      Rezek’s “Matter-of-Factness” and Its Techniques

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      Kolman, Vojtěch

      2025

      ,

      Filosofický časopis

      ,

      73

      (2)

      Esej rekonstruuje pojem věcnosti ve filosofii Petra Rezka a její zakotvení v imanenci naší zkušenosti, resp. v napětí, které vyvolávají dva požadavky na ni vázané: (1) podmíněnost věci tím, jak se jeví, a (2) současná ...

    • Fosfomycin-resistant Escherichia coli: a FosA10 case in Italy 

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      Mattioni Marchetti, Vittoria

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      Petrizzi, Ilaria

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      Venturelli, Irene

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      Cassetti, Tiziana

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      Meschiari, Marianna

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      Migliavacca, Roberta

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      Bitar, Ibrahim

      2025

      ,

      JAC-Antimicrobial Resistance

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      7

      (2)

      BACKGROUND: FosA10-producing Enterobacterales have an extremely low incidence in Europe. PATIENTS AND METHODS: In March 2024, an 83-year-old woman, hospitalized in the Modena Province, developed an infection with ...

    • Too much of everything is bad: The case of Czech university students' work-study balance during the Covid-19 pandemic 

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      Prokeš, Michaela

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      Jan, Klusáček

      2025

      ,

      Journal on Efficiency and Responsibility in Education and Science

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      18

      (2)

      Students are an exceptionally vulnerable population in comparison to any other age group. Manystudents face considerable stress stemming from the combined demands of their studies and, for some,the necessity to work. This ...

    • Survey Experiments in Public Policy: A Systematic Literature Review 

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      accepted version

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      Kovács, Radek

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      Veselý, Arnošt

      2025

      ,

      Review of Policy Research

      This systematic literature review examines population-based survey experiments (PBSE) in public policy, analyzing 36 peer-reviewed articles from Web of Science and Scopus databases. Based on PBSE methodological literature ...

    • On “Westsplaining,” Realism, and Technologies of the Self: A Foucauldian Reading of the Realist Commentary on Ukraine 

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      Kazharski, Aliaksei

      2024

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      Journal of Regional Security

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      19

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      The article offers a Foucauldian reading of the Western realist commentary on the Russo-Ukrainian war which often faces the charges of "Westsplaining." It situates this commentary in the broader context of knowledge ...