Repozitář publikační činnosti UK: Recent submissions
Now showing items 61-80 of 1772
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COVID-19 mortality data and level of democracy in post-communist countries: Data sources and accuracy
original article
open access
published version
2025
,Institute of Geonics, Czech Academy of Sciences v.v.i.
,Moravian Geographical Reports
,33
(3)
Emerging studies highlight the potential influence of different political regimes on COVID-19 mortality statistics reliability. This study has two objectives: first, to analyze COVID-19 mortality datasets and identify ...
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Decoding life expectancy gaps: a long-term decomposition analysis of three WHO European Region country groups
original article
open access
published version
2025
,Taylor & Francis
,Cogent Social Sciences
,11
(1)
Life expectancy at birth serves as a proxy measure of community health, indicating socio-economic development, healthcare accessibility, and the success of health policies. Observed differences in life expectancy among ...
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Dexamethasone Acetate-Loaded PLGA Nanospheres Targeting Liver Macrophages
original article
open access
published version
2025
,Wiley-VCH-Verl.
,Macromolecular Bioscience
,25
(2)
Glucocorticoids are potent anti-inflammatory drugs, although their use is associated with severe side effects. Loading glucocorticoids into suitable nanocarriers can significantly reduce these undesirable effects. Macrophages ...
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Compulsive exercise and physical activity in eating disorders
original article
open access
published version
2025
,Meyer & Meyer Sport
,International Journal of Sport and Exercise Psychology
,online AoP
(03 Jul 2025)
Compulsive exercise and extensive physical activity are significant symptoms of eating disorders. Compulsive exercise is one of the most persistent symptoms associated with a higher risk of relapse, chronicity, and prolonged ...
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Volební koalice ve stínu pandemie: faktory volební podpory a jejich proměna ve volbách do Poslanecké sněmovny 2017 a 2021
Electoral Coalitions in the Shadow of the Pandemic: Factors of Electoral Support and Changes to Them in the Czech Parliamentary Elections in 2017 and 2021
original article
open access
published version
2025
,Sociologický ústav AV ČR v.v.i.
,Sociologický časopis / Czech Sociological Review
,61
(4)
Tento článek mapuje změny faktorů volební podpory a jejich význam pro české politické strany sdružené ve volebních koalicích ve volbách do Poslanecké sněmovny v letech 2017 a 2021. Analýza zahrnuje i faktor úmrtnosti, který ...
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Reverse Genetics as a Key to Understanding Toscana Virus – Sand Fly Dynamics
abstract in conference proceedings
open access
accepted version
2025
,Praha
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,23
(24)
The Toscana virus (TOSV), a member of the genus Phlebovirus Phenuiviridae, Hareavirales ), is a neglected human pathogen that can cause febrile illness, severe infection of the CNS, or remain asymptomatic. It is distributed ...
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Hledání ztraceného smyslu práce: výbor textů o člověku a práci
In search of the lost meaning of work: Collection of Writings Considering Man and Work
critical commented translation
restricted access
published version
2019
,Praha
,Koridor, filosofický spolek při FHS UK
Tento výbor je prvním porevolučním akademickým překladem díla Karla Marxe. Překlad textů vybraných a editovaných Radkem Holodňákem realizoval Jakub Chavalka a Bernard Soška. Jedná se o výběr devíti zásadních filosoficko- ...
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Sand fly saliva reprograms skin fibroblasts to enhance arbovirus infection
original article
open access
published version
2025
,Cell Press, Elsevier, Inc.
,iScience
,28
(11)
Arbovirus transmission by sand flies is a growing public health concern, yet the early skin events shaping infection outcomes remain undefined. We establish a mouse model of Toscana virus (TOSV) infection that incorporates ...
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Investigating the Mechanism of Antimycobacterial and Antiproliferative Activity of (E)-N'-Benzylidenepyrazine-2-Carbohydrazides and their Derivatives
original article
open access
published version
2025
,Wiley-VCH-Verl.
,ChemMedChem
,20
(18)
A series of 33 (E)-N'-benzylidenepyrazine-2-carbohydrazides and their derivatives were synthesized and tested for biological activity. Benzylidene derivatives with 2-OH substitution on the phenyl ring (18: R = 2-OH, 21: R ...
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The discovery of a new nonbile acid modulator of Takeda G protein-coupled receptor 5: An integrated computational approach
original article
open access
published version
2025
,Wiley-VCH-Verl.
,Archiv der Pharmazie
,358
(1)
The Takeda G protein-coupled receptor 5 (TGR5), also known as GPBAR1 (G protein-coupled bile acid receptor), is a membrane-type bile acid receptor that regulates blood glucose levels and energy expenditure. These essential ...
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Biomarkers, Omics and Artificial Intelligence for Early Detection of Pancreatic Cancer
original article
open access
published version
2025
,Academic Press
,Seminars in Cancer Biology
,111
(June)
Pancreatic ductal adenocarcinoma (PDAC) is frequently diagnosed in its late stages when treatment options are limited. Unlike other common cancers, there are no population-wide screening programmes for PDAC. Thus, early ...
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A new bactericidal chlorinated derivative containing 2-aminooxazole potentiates antibacterial action of colistin against multidrug-resistant acinetobacter baumannii
original article
open access
published version
2025
,Springer
,Medical Microbiology and Immunology
,214
(1)
This comprehensive study provides insight into the antibacterial action of a recently published 2-chloro-N-(oxazol-2-yl)isonicotinamide (AB15), intending to assess its potential as a candidate adjuvant molecule to support ...
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Dysregulated mitochondrial homeostasis and DNA repair in the progression from colon adenoma to cancer
original article
open access
accepted version
2025
,North Shore-Long Island Jewish Research Institute
,Molecular Medicine
BACKGROUND: While nuclear DNA (nDNA) damage and alterations in nDNA repair are known to play a role in colon cancer (CC), there is insufficient research investigating these processes in mitochondrial DNA (mtDNA). METHODS: ...
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Teaching observation: what it is and how to implement it. Guidelines for faculty members, TLCs employees and academic decision-makers
uncertified methodology
open access
draft
2025
,Praha
,Unverzita Karlova
This guidelines provide a comprehensive framework for implementing and conducting teaching observation within higher education. It outlines essential stages of the process - from defining the purpose and selecting an ...
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The effect of emotional stimuli on static postural stability in adults: A systematic review
summarizing article
open access
published version
2026
,Elsevier BV
,Gait & Posture
,123
(neuvedeno)
BACKGROUND: Postural stability is fundamental to motor control, daily activities, and motor learning. Emerging research suggests that emotional stimuli may modulate postural responses through neural pathways linking the ...
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Yeast linear plasmid transcripts mimic viral mRNAs: evidence for a cap-independent mechanism
abstract in e-form
open access
accepted version
2025
,EMBL
,Protein synthesis and translational control
Linear plasmids have been identified in various yeast species, notably the Kluyveromyces lactis pGKL1/2 plasmids, which are cytoplasmic and serve as models for this class. These plasmids carry terminal proteins, compact ...
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An investigation into the splicing variants of human eIF4E isoforms and their distinct roles in stress
abstract in e-form
open access
accepted version
2025
,EMBL
,Protein synthesis and translational control
The eukaryotic translation initiation factor 4E (eIF4E) binds to the 5' mRNA cap and plays a pivotal role in the control of cap-dependent translation initiation. The human eIF4E protein family comprises canonical eIF4E1 ...
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STING agonists induce pyroptotic apoptosis in human monocytes
abstract in conference proceedings
open access
accepted version
2025
,Praha
,Česká společnost chemická
,Czech Chemical Society Symposium Series
,23
(4)
Regulated cell death (RCD) represents a key outcome of the cyclic GMP GMP-AMP synthase (cGAS) cGAS)-stimulator of interferon genes (STING) activation in human monocytes, in addition to its canonical role in sensing cytoplasmic ...
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Relationship between MASLD and women's health: A review
summarizing article
open access
published version
2025
,SAGE Publications Ltd
,Women's Health
,21
(October)
Metabolic dysfunction-associated steatotic liver disease (MASLD; formerly non-alcoholic fatty liver disease, NAFLD) is a common chronic liver disease strongly linked to obesity, metabolic syndrome (MetS), and type 2 diabetes. ...
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Neurčité užití pojmů ve Waismannově pojetí
Indeterminate Use of the Notions in Waismann's Philosophy
article in reviewed proceedings
open access
published version
2016
,Trnava
,Trnavská univerzita
,Nová Európa - Výzvy a očakávania
Příspěvek se zabývá neurčitostí užití jazykového vyjádření zákonodárce v pojetí Friedricha Waismanna, s nímž je spojeno zavedení pojmu otevřené textury do filozofie jazyka. Ačkoliv je tento pojem v právním myšlení popularizován ...
