Zobrazují se záznamy 1181-1200 z 1838

    • Specific Immunity to SARS-CoV-2 Infection 

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      Vránová, Lucie

      ;

      Poláková, Ingrid

      ;

      Tachezy, Ruth

      ;

      Vaníková, Šárka

      ;

      Musil, Jan

      ;

      Saláková, Martina

      ;

      Vaníčková, Marie

      ;

      Vencálek, Ondřej

      ;

      Holub, Michal

      ;

      Bohoněk, Miloš

      ;

      Beran, Ondřej

      ;

      Řezáč, David

      ;

      Dresler, Jiří

      ;

      Kabíčková, Hana

      ;

      Šmahel, Michal

      2024

      ,

      Praha

      ,

      Česká zemědělská univerzita

      ,

      CzechoSlovak Virology Conference 2024 : Book of Abstracts

      ,

      1

      (1)

      The SARS-CoV-2 coronavirus, causing COVID-19 disease, has killed almost 7 million people worldwide.For effective treatment and introduction of appropriate anti-pandemic measures, it is necessary tounderstand the development ...

    • The differences in virome from distinct anatomical locations in psoriasis patients 

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      Kadlečková, Dominika

      ;

      Saláková, Martina

      ;

      Šmahelová, Jana

      ;

      Rob, Filip

      ;

      Nováková, Michaela

      ;

      Tachezy, Ruth

      2024

      ,

      Praha

      ,

      Česká zemědělská univerzita

      ,

      CzechoSlovak Virology Conference 2024 : Book of Abstracts

      ,

      1

      (1)

      Psoriasis, a chronic autoimmune inflammatory disorder affecting 2-3% of the global population,exhibits a multifactorial aetiology with a significant genetic component and triggers such as trauma orinfection.

    • UV-C irradiation as an effective tool for sterilization of porcine chimeric VP1-PCV2bCap recombinant vaccine 

      původní článek

      open access

      vydavatelská verze

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      Vráblíková, Alena

      ;

      Fojtíková, Martina

      ;

      Héžová, Renata

      ;

      Šimečková, Pavlína

      ;

      Brezáni, Veronika

      ;

      Straková, Nicol

      ;

      Fraiberk, Martin

      ;

      Kotouček, Jan

      ;

      Mašek, Josef

      ;

      Pšikal, Ivan

      2023

      ,

      Scientific Reports

      ,

      13

      (1)

      Ultraviolet irradiation is an effective method of virus and bacteria inactivation. The dose of UV-C light necessary for baculovirus inactivation by measurement of fluorescent GFP protein produced by baculovirus expression ...

    • Hepatitis B virus hijacks host E2/E3 ubiquitin ligase, UBE2O, for viral nucleocapsid assembly and virion egress 

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      Lubyová, Barbora

      ;

      Tikalová, Eva

      ;

      Janovec, Václav

      ;

      Rjabčenko, Boris

      ;

      Krulová, Kristýna

      ;

      Huerfano Meneses, Sandra

      ;

      Hirsch, Ivan

      ;

      Weber, Jan

      2024

      ,

      Praha

      ,

      CzechoSlovak Virology Conference 2024 : Book of abstracts

      ,

      1

      (1)

      Chronic hepatitis B (CHB) represents a serious liver disease that is caused by infection of Hepatitis Bvirus (HBV). CHB is associated with severe liver conditions ranging from fibrosis and cirrhosis tohepatocellular carcinoma ...

    • Aristotelés o studu a ctnosti 

      Aristotle on Shame and Virtue

      původní článek

      open access

      vydavatelská verze

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      Synek, Stanislav

      2023

      ,

      Aither

      ,

      15

      (29)

      Článek se zabývá problematickými aspekty Aristotelova pojetí studu (aidós) a jeho vztahem ke ctnosti. Stud je Aristotelem na jedné straně představen jako specifická emoce (pathé), na straně druhé však zároveň jako "střednost" ...

    • Effect of ADAR1 enzyme knockout on HCV replication 

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      Kubů, Martin

      ;

      Pospíšek, Martin

      ;

      Vopálenský, Václav

      ;

      Roučová, Kristina

      2024

      ,

      Praha

      ,

      Česká zemědělská univerzita

      ,

      CzechoSlovak Virology Conference 2024 : Book of abstracts

      ,

      1

      (1)

      The hepatitis C virus (HCV) is a member of the Flaviviridae family whose genome consists of a +RNAmolecule. It causes hepatitis C, a disease that affects tens of millions of people worldwide. Althoughthere is an effective ...

    • Inhibition of HBsAg secretion by a novel autophagy inducer 

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      Pimková Polidarová, Markéta

      ;

      Janovec, Václav

      ;

      Berehovska, Olena

      ;

      Kůtová, Zuzana

      ;

      Sedláček, Jindřich

      ;

      Adámek, Michael

      ;

      Machara, Aleš

      ;

      Hirsch, Ivan

      ;

      Grantz Šašková, Klára

      2024

      ,

      Praha

      ,

      Česká zemědělská univerzita v Praze

      ,

      CzechoSlovak Virology Conference 2024 : Book of Abstracts

      ,

      1

      (1)

      Chronic hepatitis B (CHB) is a viral liver infection caused by hepatitis B virus (HBV), affecting over 300 million people world-wide. Untreated CHB can lead to liver cirrhosis and hepatocellular carcinoma, causing over ...

    • Development of modern immunization agent against bovine papillomavirus type 1 infection based on BPV1 L1 recombinant protein 

      původní článek

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      vydavatelská verze

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      Vráblíková, Alena

      ;

      Brezáni, Veronika

      ;

      Pšikal, Ivan

      ;

      Fraiberk, Martin

      ;

      Šebela, Marek

      ;

      Fojtíková, Martina

      ;

      Kulich, Pavel

      ;

      Héžová, Renata

      ;

      Mašek, Josef

      2023

      ,

      Frontiers in Veterinary Science

      ,

      10

      (March)

      Bovine papillomavirus type 1 L1 protein was produced in a baculovirus expression system and purified as virus-like particles (VLPs) by affinity chromatography using lectins. The morphological integrity of VLPs was confirmed ...

    • Aristotle on Pain: Pain as hindering the energia in the Nicomachean Ethics 

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      open access

      vydavatelská verze

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      Linka, Vojtěch

      2023

      ,

      Aither

      ,

      30

      (15)

      This paper endeavours to examine the function of pain in Aristotle's ethical philosophy. First, it delves into the relationship between pleasure and activity before directing its attention towards the relationship between ...

    • Conspiracy Narratives as a Type of Social Myth 

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      Chlup, Radek

      2024

      ,

      International Journal of Politics, Culture, and Society

      ,

      2024

      (37)

      It has long been recognized that conspiracy narratives may be seen as a special kind of myth. In most cases, however, this is taken as a sign of their irrational and unsubstantiated nature. I argue that mythical modes of ...

    • Migration to the Czech Republic: Personal Stories About Running from and Running Towards 

      kapitola v monografii

      omezený přístup

      vydavatelská verze

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      Gheorghiev, Olga

      ;

      Numerato, Dino

      2023

      ,

      Cham

      ,

      Springer

      ,

      Immigrant and Asylum Seekers Labour Market Integration upon Arrival: NowHereLand

      The chapter focuses on micro perspectives expressed in individual trajectories of migrants, refugees, and asylum seekers (MRAs) in the Czech Republic. Drawing on 14 in-depth biographic interviews with MRAs, this chapter ...

    • Antifungal triazoles affect key non-target metabolic pathways in Solanum lycopersicum L. plants 

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      vydavatelská verze

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      Hýsková, Veronika

      ;

      Jakl, Michal

      ;

      Jaklová Dytrtová, Jana

      ;

      Zeljković, Sanja Ćavar

      ;

      Vrobel, Ondřej

      ;

      Bělonožníková, Kateřina

      ;

      Kavan, Daniel

      ;

      Křížek, Tomáš

      ;

      Šimonová, Alice

      ;

      Vašková, Marie

      ;

      Kovač, Ishak

      ;

      Račko Žufić, Antoniana

      ;

      Ryšlavá, Helena

      2023

      ,

      Ecotoxicology and Environmental Safety

      ,

      268

      (December)

      Several 1,2,4-triazoles are widely used as systemic fungicides in agriculture because they inhibit fungal 14ɑ-demethylase. However, they can also act on many non-target plant enzymes, thereby affecting phytohormonal balance, ...

    • Triazoles as a Potential Threat to the Nutritional Quality of Tomato Fruits 

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      Hýsková, Veronika

      ;

      Jakl, Michal

      ;

      Jaklová Dytrtová, Jana

      ;

      Cavar Zeljkovic, Sanja

      ;

      Vrobel, Ondrej

      ;

      Bělonožníková, Kateřina

      ;

      Kavan, Daniel

      ;

      Křížek, Tomáš

      ;

      Šimonová, Alice

      ;

      Vašková, Marie

      ;

      Kovač, Ishak

      ;

      Račko Žufić, Antoniana

      ;

      Ryšlavá, Helena

      2023

      ,

      Metabolites

      ,

      13

      (9)

      Triazole fungicides can threaten plants as abiotic stressors but can also positively affect plant defense by inducing priming. Thus, plant yield is also both protected and endangered by triazoles that may influence several ...

    • Novel sulfonamide derivatives as a tool to combat methicillin-resistant Staphylococcus aureus 

      přehledový článek

      open access

      vydavatelská verze

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      Krátký, Martin

      2024

      ,

      Future Medicinal Chemistry

      ,

      16

      (6)

      Increasing resistance in Staphylococcus aureus has created a critical need for new drugs, especially those effective against methicillin-resistant strains (methicillin-resistant Staphylococcus aureus [MRSA]). Sulfonamides ...

    • Synthesis and migrastatic activity of cytochalasin analogues lacking a macrocyclic moiety 

      původní článek

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      vydavatelská verze

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      Formánek, Bedřich

      ;

      Dupommier, Dorian

      ;

      Volfová, Tereza

      ;

      Rimpelová, Silvie

      ;

      Škarková, Aneta

      ;

      Herciková, Jana

      ;

      Rösel, Daniel

      ;

      Brábek, Jan

      ;

      Perlíková, Pavla

      2024

      ,

      Royal Society of Chemistry

      ,

      RSC Medicinal Chemistry

      ,

      15

      (1)

      Cytochalasans are known as inhibitors of actin polymerization and for their cytotoxic and migrastatic activity. In this study, we synthesized a series of cytochalasin derivatives that lack a macrocyclic moiety, a structural ...

    • Díla Jana Marka Marci z Kronlandu ve fondu 1. lékařské fakulty Univerzity Karlovy 

      The Work of Johannes Marcus Marci of Cronland in the Book Collection of the First Faculty of Medicine at Charles University

      původní článek

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      vydavatelská verze

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      Ivánková, Markéta

      2020

      ,

      Knihy a dějiny

      ,

      27

      (1-2)

      Soubor šesti svazků (deseti děl) Jana Marka Marci z Kronlandu na 1. lékařské fakultě Univerzity Karlovy lze plným právem označit za průřezovou sbírku jeho děl. Vyznačují se vysokou uměleckou úrovní a dobrou typografií. ...

    • Dark Side of the Principles of Non-discrimination and Proportionality : the Case of Mandatory Vaccination 

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      Horák, Filip

      ;

      Dienstbier, Jakub

      2025

      ,

      Journal of Medical Ethics

      ,

      2025

      (10)

      Deciding the conflict between various rights and interests, especially in medical ethics where health and lives are in question, has significant challenges, and to obtain appropriate outcomes, it is necessary to properly ...

    • Nutritional practices and experiences of people on vegan diet with healthcare system: a qualitative study 

      přehledový článek

      open access

      vydavatelská verze

      Ikona Jiná licence

      Borisova, Varvara

      ;

      Stöckelová, Tereza

      ;

      Ouřadová, Anna

      ;

      Gojda, Jan

      2023

      ,

      Central European Journal of Public Health

      ,

      31

      (3)

      OBJECTIVES: The growing popularity of diets that restrict the consumption of animal-based foods is an important new challenge for the public healthcare system in Czechia. While the environmental and health-related benefits ...

    • Bosnian-Herzegovinian Citizens in the Making : The Citizenship Debate in the Time of Social Mobilizations 

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      Chrzová, Barbora

      2024

      ,

      Nationalities Papers

      ,

      52

      (1)

      Drawing upon rhetorical approaches to citizenship, this article analyzes how the contested notion of Bosnian-Herzegovinian (BiH) citizenship has been crafted on the discursive level during two series of social mobilizations ...

    • A recurrent synonymous L1CAM variant in a fetus with hydrocephalus 

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      Šubrt, Ivan

      ;

      Zavoral, Tomáš

      ;

      Strych, Lukáš

      ;

      Černá, Monika

      ;

      Hejnalová, Markéta

      ;

      Komrsková, Pavla

      ;

      Tejcová, Jitka

      2024

      ,

      Human Genome Variation

      ,

      11

      (1)

      We report the case of a hydrocephalic fetus in which clinical exome sequencing revealed a recurrent synonymous variant of unknown significance, c.453G>T, in the L1CAM gene. This report presents the second case of X-linked ...