dc.contributor.author | Pimková Polidarová, Markéta | |
dc.contributor.author | Hirsch, Ivan | |
dc.contributor.author | Berehovska, Olena | |
dc.contributor.author | Janovec, Václav | |
dc.contributor.author | Brázdová, Andrea | |
dc.contributor.author | Grantz Šašková, Klára | |
dc.date.accessioned | 2023-10-09T10:40:26Z | |
dc.date.available | 2023-10-09T10:40:26Z | |
dc.date.issued | 2023 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14178/2042 | |
dc.description.abstract | The cyclic-GMP-AMP synthase - stimulator of interferon genes (cGAS-STING) pathwayrecognizes cytosolic double-stranded DNA (dsDNA), a sign of viral infection or cell damage.Activation of the pathway stimulates immune cells to secrete type I interferons (IFNs) andvarious proinflammatory cytokines. These immunomodulatory proteins further induce multipleregulatory immune processes with antiviral or antitumoral properties. | en |
dc.language.iso | en | |
dc.rights | Creative Commons Uveďte původ 4.0 International | cs |
dc.rights | Creative Commons Attribution 4.0 International | en |
dc.title | STING agonist-induced cytokine production with anti-HBV activity is accompanied by immunogenic cell death of monocytes | en |
dcterms.accessRights | openAccess | |
dcterms.license | https://creativecommons.org/licenses/by/4.0/legalcode | |
dc.date.updated | 2023-10-09T10:40:26Z | |
dc.subject.keyword | STING | en |
dc.subject.keyword | cyclic-GMP-AMP | en |
dc.subject.keyword | agonist-treated | en |
dc.relation.fundingReference | info:eu-repo/grantAgreement/MSM//LX22NPO5103 | |
dc.date.embargoStartDate | 2023-10-09 | |
dc.contributor.organizer | Hepatitis B Foundation | |
dc.type.obd | 110 | |
dc.type.version | info:eu-repo/semantics/acceptedVersion | |
dc.identifier.obd | 636933 | |
dc.subject.rivPrimary | 30000::30100::30102 | |
dc.subject.rivSecondary | 10000::10600::10607 | |
dcterms.isPartOf.journalYear | 2023 | |
uk.faculty.primaryId | 115 | |
uk.faculty.primaryName | Přírodovědecká fakulta | cs |
uk.faculty.primaryName | Faculty of Science | en |
uk.department.primaryId | 1034 | |
uk.department.primaryName | Katedra genetiky a mikrobiologie | cs |
uk.department.primaryName | Department of Genetics and Microbiology | en |
uk.event.name | HBV International Meeting | |
dc.description.pageRange | nestránkováno | |
dc.type.obdHierarchyCs | ABSTRAKT::abstrakt::abstrakt v elektronické podobě | cs |
dc.type.obdHierarchyEn | ABSTRACT::abstract::abstract in e-form | en |
dc.type.obdHierarchyCode | 110::130::136 | en |
uk.displayTitle | STING agonist-induced cytokine production with anti-HBV activity is accompanied by immunogenic cell death of monocytes | en |