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Nutritional practices and experiences of people on vegan diet with healthcare system: a qualitative study
(2023)
OBJECTIVES: The growing popularity of diets that restrict the consumption of animal-based foods is an important new challenge for the public healthcare system in Czechia. While the environmental and health-related benefits ...
Atrial fibrillation therapy and stroke prevention in hemodialysis patients
(2023)
The prevalence of atrial fibrillation (AF) in patients with chronic kidney disease (CKD), especially on hemodialysis (HD) is higher compared to the general population without CKD and reaches ~20%. The risk of ischemic ...
Frentizole derivatives with mTOR inhibiting and senomorphic properties
(2023)
Frentizole is immunosuppressive drug with low acute toxicity and lifespan-prolonging effect. Recently, frentizole's potential to disrupt toxic amyloid β (Aβ) - Aβ-binding alcohol dehydrogenase (ABAD) interaction in ...
Muscle Lipid Oxidation Is Not Affected by Obstructive Sleep Apnea in Diabetes and Healthy Subjects
(2023)
The molecular mechanisms linking obstructive sleep apnea (OSA) with type 2 diabetes mellitus (T2DM) remain unclear. This study investigated the effect of OSA on skeletal muscle lipid oxidation in nondiabetic controls and ...
Acute ischaemic stroke: recent advances in reperfusion treatment
(2023)
During the last 5-7 years, tremendous progress was achieved in the reperfusion treatment of acute ischaemic stroke during its first few hours from symptom onset. This review summarizes the latest evidence from randomized ...
Electrophysiological and computational analysis of Ca(v)3.2 channel variants associated with familial trigeminal neuralgia
(2022)
Trigeminal neuralgia (TN) is a rare form of chronic neuropathic pain characterized by spontaneous or elicited paroxysms of electric shock-like or stabbing pain in a region of the face. While most cases occur in a sporadic ...
T-wave inversions during conduction system pacing: A marker of more physiological ventricular activation
(2022)
Permanent myocardial pacing can preserve adequate heart rates and improve symptoms and mortality in patients with bradycardia. Conventional right ventricular (RV) pacing is far from the optimal treatment since up to 20% ...
Left ventricular resynchronization with left bundle branch area pacing: does the type of capture matter?
(2023)
Cardiac resynchronization therapy (CRT) with biventricular pacing (BiV) has been a mainstream treatment in heart failure patients with wide QRS complexes for two decades. In recent years, left bundle branch pacing (LBBP) ...
Left ventricular septal pacing - can we trust the ECG?
(2023)
In contrast to left bundle branch pacing, the criteria for left ventricular septal pacing (LVSP) were never validated. LVSP is usually defined as deep septal deployment of the pacing lead with a pseudo-right bundle branch ...
Resynchronization for shifting conduction patterns - When a coronary sinus lead is not enough
(2023)
A 60-year-old patient with heart failure (NYHA II) due to non-ischemic cardiomyopathy with a left ventricular end-diastolic diameter (LVEDD) of 73 mm and left ventricular ejection fraction (LVEF) 20% presented with ...